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Aliases for ARL17B Gene

Aliases for ARL17B Gene

  • ADP-Ribosylation Factor-Like 17B 2 3
  • ARL17A 3 4
  • ADP-Ribosylation Factor-Like Protein 17 3
  • ADP-Ribosylation Factor 7 Variant 4
  • ADP-Ribosylation Factor-Like 17 2
  • ADP-Ribosylation Factor 7 3
  • ARL17A ARL17B 4
  • ARL17P1 4
  • ARF1P2 4
  • ARL17 3

External Ids for ARL17B Gene

Previous HGNC Symbols for ARL17B Gene

  • ARL17

Previous GeneCards Identifiers for ARL17B Gene

  • GC17M041732
  • GC17M044596
  • GC17Pp43777
  • GC17M044377
  • GC17M044352

Summaries for ARL17B Gene

GeneCards Summary for ARL17B Gene

ARL17B (ADP-Ribosylation Factor-Like 17B) is a Protein Coding gene. GO annotations related to this gene include GTP binding. An important paralog of this gene is ARL17A.

UniProtKB/Swiss-Prot for ARL17B Gene

  • GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity).

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARL17B Gene

Genomics for ARL17B Gene

Genomic Location for ARL17B Gene

46,274,184 bp from pter
46,362,046 bp from pter
87,863 bases
Minus strand

Genomic View for ARL17B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ARL17B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARL17B Gene

No data available for Regulatory Elements for ARL17B Gene

Proteins for ARL17B Gene

  • Protein details for ARL17B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    ADP-ribosylation factor-like protein 17
    Protein Accession:
    Secondary Accessions:
    • B0AZR6
    • Q59FW5
    • Q8N6E2
    • Q8TD73
    • Q8WW54
    • Q9NZD5
    • Q9P158

    Protein attributes for ARL17B Gene

    177 amino acids
    Molecular mass:
    19388 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAF64278.1; Type=Frameshift; Positions=114; Evidence={ECO:0000305}; Sequence=AAF69643.1; Type=Frameshift; Positions=17; Evidence={ECO:0000305}; Sequence=AAH30570.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAD92581.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ARL17B Gene


neXtProt entry for ARL17B Gene

Proteomics data for ARL17B Gene at MOPED

Post-translational modifications for ARL17B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ARL17B Gene

Domains for ARL17B Gene

Gene Families for ARL17B Gene

  • ARF :ADP-ribosylation factors
  • ARL :ADP-ribosylation factors-like

Protein Domains for ARL17B Gene

Suggested Antigen Peptide Sequences for ARL17B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q8IVW1
  • Belongs to the small GTPase superfamily. Arf family.
genes like me logo Genes that share domains with ARL17B: view

Function for ARL17B Gene

Molecular function for ARL17B Gene

UniProtKB/Swiss-Prot Function:
GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity).

Gene Ontology (GO) - Molecular Function for ARL17B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005525 GTP binding IEA --
genes like me logo Genes that share ontologies with ARL17B: view

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ARL17B

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ARL17B Gene

Localization for ARL17B Gene

Subcellular locations from UniProtKB/Swiss-Prot for ARL17B Gene

Golgi apparatus.

Subcellular locations from

Jensen Localization Image for ARL17B Gene COMPARTMENTS Subcellular localization image for ARL17B gene
Compartment Confidence
cytosol 3
extracellular 2
golgi apparatus 2
endoplasmic reticulum 1
mitochondrion 1
nucleus 1

Gene Ontology (GO) - Cellular Components for ARL17B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005794 Golgi apparatus IEA --
genes like me logo Genes that share ontologies with ARL17B: view

Pathways for ARL17B Gene

SuperPathways for ARL17B Gene

No Data Available

Interacting Proteins for ARL17B Gene

Gene Ontology (GO) - Biological Process for ARL17B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007264 small GTPase mediated signal transduction IEA --
GO:0015031 protein transport IEA --
GO:0016192 vesicle-mediated transport IEA --
genes like me logo Genes that share ontologies with ARL17B: view

No data available for Pathways by source for ARL17B Gene

Transcripts for ARL17B Gene

mRNA/cDNA for ARL17B Gene

(10) Additional mRNA sequences :
(11) REFSEQ mRNAs :
(8) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ARL17B Gene

ADP-ribosylation factor-like 17B:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ARL17B

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ARL17B Gene

No ASD Table

Relevant External Links for ARL17B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ARL17B Gene

mRNA expression in normal human tissues for ARL17B Gene

Protein differential expression in normal tissues for ARL17B Gene

This gene is overexpressed in Cerebrospinal fluid (67.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ARL17B Gene

SOURCE GeneReport for Unigene cluster for ARL17B Gene Hs.720602

genes like me logo Genes that share expressions with ARL17B: view

Expression partners for ARL17B Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ARL17B Gene

Orthologs for ARL17B Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ARL17B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 36
  • 99 (a)
-- 36
  • 81 (a)
-- 36
  • 76 (a)
Species with no ortholog for ARL17B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ARL17B Gene

Gene Tree for ARL17B (if available)
Gene Tree for ARL17B (if available)

Paralogs for ARL17B Gene

Paralogs for ARL17B Gene

Selected SIMAP similar genes for ARL17B Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ARL17B: view

Variants for ARL17B Gene

Sequence variations from dbSNP and Humsavar for ARL17B Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs62073913 -- 46,355,525(+) GTAAC(A/G)AAGAA intron-variant
rs146306618 -- 46,355,525(+) GTAAC(-/AAA)GAAGG intron-variant
rs201886329 -- 46,352,283(+) ACAGT(-/A)AAAAA intron-variant
rs371122498 -- 46,354,941(+) CATCC(-/AAGAAAGAA)AAGAA intron-variant
rs372087314 -- 46,358,060(+) GATAT(-/ATA)ATATA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ARL17B Gene

Variant ID Type Subtype PubMed ID
dgv127e55 CNV Gain 17911159
nsv471698 CNV Gain+Loss 15918152
dgv972e1 CNV Complex 17122850
dgv973e1 CNV Complex 17122850
dgv974e1 CNV Complex 17122850
dgv975e1 CNV Complex 17122850
dgv976e1 CNV Complex 17122850
nsv516807 CNV Gain+Loss 19592680
dgv3183n71 CNV Gain 21882294
nsv908315 CNV Gain 21882294
nsv821687 CNV Gain 15273396
dgv977e1 CNV Complex 17122850
esv33048 CNV Gain+Loss 17666407
nsv9564 CNV Gain+Loss 18304495
esv21783 CNV Gain+Loss 19812545
dgv978e1 CNV Complex 17122850
nsv469697 CNV Complex 16826518
dgv982e1 CNV Complex 17122850
esv2656635 CNV Deletion 23128226
nsv908326 CNV Gain 21882294
nsv908327 CNV Loss 21882294
dgv3185n71 CNV Gain 21882294
nsv908329 CNV Gain 21882294
dgv13n31 CNV Duplication 19718026
nsv2070 CNV Loss 18451855
nsv511057 CNV Complex 20534489
dgv3186n71 CNV Loss 21882294
nsv163 CNV Loss 15895083
dgv3187n71 CNV Gain 21882294
nsv821581 CNV Deletion 20802225
nsv908334 CNV Gain+Loss 21882294
dgv3188n71 CNV Gain 21882294
dgv983e1 CNV Complex 17122850
dgv984e1 CNV Complex 17122850
dgv985e1 CNV Complex 17122850
nsv428343 CNV Gain+Loss 18775914
nsv442749 CNV CNV 18776908
dgv3189n71 CNV Loss 21882294
dgv3190n71 CNV Gain+Loss 21882294
dgv3191n71 CNV Loss 21882294
dgv3192n71 CNV Gain+Loss 21882294
dgv3193n71 CNV Gain 21882294
dgv3194n71 CNV Loss 21882294
dgv3195n71 CNV Gain+Loss 21882294
dgv3196n71 CNV Gain 21882294
esv1003686 CNV Gain 20482838
dgv3197n71 CNV Gain 21882294
dgv3198n71 CNV Gain 21882294
esv2421412 OTHER Complex 20811451
dgv15n14 CNV Loss 18776910
nsv819319 CNV Loss 19587683
dgv3199n71 CNV Gain+Loss 21882294
dgv3200n71 CNV Loss 21882294
dgv3201n71 CNV Loss 21882294

Relevant External Links for ARL17B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ARL17B Gene

Disorders for ARL17B Gene

No disorders were found for ARL17B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for ARL17B Gene

Publications for ARL17B Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PMID: 19608861) Choudhary C. … Mann M. (Science 2009) 3
  4. Global identification of modular cullin-RING ligase substrates. (PMID: 21963094) Emanuele M.J. … Elledge S.J. (Cell 2011) 3
  5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3

Products for ARL17B Gene

Sources for ARL17B Gene

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