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Aliases for ARL16 Gene

Aliases for ARL16 Gene

  • ADP-Ribosylation Factor-Like 16 2 3

External Ids for ARL16 Gene

Summaries for ARL16 Gene

GeneCards Summary for ARL16 Gene

ARL16 (ADP-Ribosylation Factor-Like 16) is a Protein Coding gene. GO annotations related to this gene include GTP binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARL16 Gene

Genomics for ARL16 Gene

Genomic Location for ARL16 Gene

Start:
81,681,174 bp from pter
End:
81,683,924 bp from pter
Size:
2,751 bases
Orientation:
Minus strand

Genomic View for ARL16 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ARL16 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARL16 Gene

Regulatory Elements for ARL16 Gene

Proteins for ARL16 Gene

  • Protein details for ARL16 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q0P5N6-ARL16_HUMAN
    Recommended name:
    ADP-ribosylation factor-like protein 16
    Protein Accession:
    Q0P5N6
    Secondary Accessions:

    Protein attributes for ARL16 Gene

    Size:
    197 amino acids
    Molecular mass:
    20936 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ARL16 Gene

Proteomics data for ARL16 Gene at MOPED

Post-translational modifications for ARL16 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ARL16 Gene

Domains for ARL16 Gene

Gene Families for ARL16 Gene

HGNC:
  • ARL :ADP-ribosylation factors-like
  • ARF :ADP-ribosylation factors

Protein Domains for ARL16 Gene

UniProtKB/Swiss-Prot:

ARL16_HUMAN
Family:
  • Belongs to the small GTPase superfamily. Arf family.:
    • Q0P5N6
genes like me logo Genes that share domains with ARL16: view

Function for ARL16 Gene

Gene Ontology (GO) - Molecular Function for ARL16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0005525 GTP binding IEA --
genes like me logo Genes that share ontologies with ARL16: view

miRNA for ARL16 Gene

miRTarBase miRNAs that target ARL16

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ARL16 Gene

Localization for ARL16 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ARL16 Gene COMPARTMENTS Subcellular localization image for ARL16 gene
Compartment Confidence
cytosol 2
mitochondrion 2
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for ARL16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with ARL16: view

Pathways for ARL16 Gene

SuperPathways for ARL16 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ARL16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006886 intracellular protein transport --
GO:0007264 small GTPase mediated signal transduction IEA --
genes like me logo Genes that share ontologies with ARL16: view

No data available for Pathways by source for ARL16 Gene

Transcripts for ARL16 Gene

Unigene Clusters for ARL16 Gene

ADP-ribosylation factor-like 16:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ARL16 Gene

No ASD Table

Relevant External Links for ARL16 Gene

GeneLoc Exon Structure for
ARL16
ECgene alternative splicing isoforms for
ARL16

Expression for ARL16 Gene

mRNA expression in normal human tissues for ARL16 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ARL16 Gene

SOURCE GeneReport for Unigene cluster for ARL16 Gene Hs.658789

genes like me logo Genes that share expressions with ARL16: view

Orthologs for ARL16 Gene

This gene was present in the common ancestor of animals.

Orthologs for ARL16 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ARL16 36
  • 99.32 (n)
  • 99.49 (a)
ARL16 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ARL16 36
  • 86.55 (n)
  • 86.14 (a)
ARL16 37
  • 79 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ARL16 36
  • 85.08 (n)
  • 84.3 (a)
ARL16 37
  • 81 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Arl16 36
  • 84.71 (n)
  • 86.47 (a)
Arl16 16
Arl16 37
  • 85 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ARL16 37
  • 83 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Arl16 36
  • 83.33 (n)
  • 85.88 (a)
chicken
(Gallus gallus)
Aves ARL16 36
  • 70.27 (n)
  • 69.89 (a)
ARL16 37
  • 62 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ARL16 37
  • 68 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia arl16 36
  • 62.36 (n)
  • 59.18 (a)
Str.10245 36
zebrafish
(Danio rerio)
Actinopterygii arl16 36
  • 59.13 (n)
  • 60.71 (a)
arl16 37
  • 59 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG13692 37
  • 21 (a)
OneToOne
Species with no ortholog for ARL16:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ARL16 Gene

ENSEMBL:
Gene Tree for ARL16 (if available)
TreeFam:
Gene Tree for ARL16 (if available)

Paralogs for ARL16 Gene

Pseudogenes.org Pseudogenes for ARL16 Gene

genes like me logo Genes that share paralogs with ARL16: view

No data available for Paralogs for ARL16 Gene

Variants for ARL16 Gene

Sequence variations from dbSNP and Humsavar for ARL16 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs1134381 -- 81,681,336(-) TAATC(C/T)CAGCT utr-variant-3-prime
rs7359609 -- 81,680,832(+) GTCTC(A/G)AACTC downstream-variant-500B
rs8076090 -- 81,681,497(+) TGCCT(A/G)GCCCC utr-variant-3-prime
rs9907803 -- 81,681,005(+) ACCAG(C/T)GGCTC downstream-variant-500B
rs11548422 -- 81,681,231(-) GAGTG(A/T)AACTC utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ARL16 Gene

Variant ID Type Subtype PubMed ID
esv26223 CNV Gain+Loss 19812545
nsv828128 CNV Loss 20364138
nsv909052 CNV Loss 21882294
nsv428351 CNV Gain 18775914
dgv3330n71 CNV Loss 21882294
dgv3332n71 CNV Loss 21882294
nsv470620 CNV Loss 18288195
nsv909109 CNV Loss 21882294
dgv3333n71 CNV Loss 21882294
nsv909116 CNV Loss 21882294

Relevant External Links for ARL16 Gene

HapMap Linkage Disequilibrium report
ARL16

Disorders for ARL16 Gene

No disorders were found for ARL16 Gene.

No data available for UniProtKB/Swiss-Prot for ARL16 Gene

Publications for ARL16 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. ARF-like protein 16 (ARL16) inhibits RIG-I by binding with its C-terminal domain in a GTP-dependent manner. (PMID: 21233210) Yang Y.K. … Chen D.Y. (J. Biol. Chem. 2011) 3
  5. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3

Products for ARL16 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ARL16
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ARL16
    • Block miRNA regulation of ARL16 using miScript Target Protectors

    Sources for ARL16 Gene

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