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Aliases for ARL15 Gene

Aliases for ARL15 Gene

  • ADP-Ribosylation Factor-Like 15 2 3
  • ADP-Ribosylation Factor Related Protein 2 2 3
  • ADP-Ribosylation Factor-Related Protein 2 3 4
  • ARF-Related Protein 2 3 4
  • ARFRP2 3 4
  • ADP-Ribosylation Factor-Like Protein 15 3

External Ids for ARL15 Gene

Previous Symbols for ARL15 Gene

  • ARFRP2

Summaries for ARL15 Gene

GeneCards Summary for ARL15 Gene

ARL15 (ADP-Ribosylation Factor-Like 15) is a Protein Coding gene. GO annotations related to this gene include GTP binding. An important paralog of this gene is ARL1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARL15 Gene

Genomics for ARL15 Gene

Genomic Location for ARL15 Gene

Start:
53,883,945 bp from pter
End:
54,310,582 bp from pter
Size:
426,638 bases
Orientation:
Minus strand

Genomic View for ARL15 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ARL15 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARL15 Gene

Regulatory Elements for ARL15 Gene

Proteins for ARL15 Gene

  • Protein details for ARL15 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NXU5-ARL15_HUMAN
    Recommended name:
    ADP-ribosylation factor-like protein 15
    Protein Accession:
    Q9NXU5
    Secondary Accessions:
    • Q6IAD0

    Protein attributes for ARL15 Gene

    Size:
    204 amino acids
    Molecular mass:
    22876 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ARL15 Gene

Proteomics data for ARL15 Gene at MOPED

Post-translational modifications for ARL15 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys157

Other Protein References for ARL15 Gene

No data available for DME Specific Peptides for ARL15 Gene

Domains for ARL15 Gene

Gene Families for ARL15 Gene

HGNC:
  • ARL :ADP-ribosylation factors-like
  • ARF :ADP-ribosylation factors

Protein Domains for ARL15 Gene

UniProtKB/Swiss-Prot:

ARL15_HUMAN
Family:
  • Belongs to the small GTPase superfamily. Arf family.:
    • Q9NXU5
genes like me logo Genes that share domains with ARL15: view

Function for ARL15 Gene

Gene Ontology (GO) - Molecular Function for ARL15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0005525 GTP binding IEA --
genes like me logo Genes that share ontologies with ARL15: view

miRNA for ARL15 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ARL15 Gene

Localization for ARL15 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ARL15 Gene COMPARTMENTS Subcellular localization image for ARL15 gene
Compartment Confidence
cytosol 3
nucleus 2
extracellular 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for ARL15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus --
GO:0005737 cytoplasm --
GO:0070062 extracellular exosome IDA 19056867
genes like me logo Genes that share ontologies with ARL15: view

Pathways for ARL15 Gene

SuperPathways for ARL15 Gene

No Data Available

Interacting Proteins for ARL15 Gene

Gene Ontology (GO) - Biological Process for ARL15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006886 intracellular protein transport --
GO:0007264 small GTPase mediated signal transduction IEA --
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with ARL15: view

No data available for Pathways by source for ARL15 Gene

Transcripts for ARL15 Gene

Unigene Clusters for ARL15 Gene

ADP-ribosylation factor-like 15:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ARL15 Gene

No ASD Table

Relevant External Links for ARL15 Gene

GeneLoc Exon Structure for
ARL15
ECgene alternative splicing isoforms for
ARL15

Expression for ARL15 Gene

mRNA expression in normal human tissues for ARL15 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ARL15 Gene

SOURCE GeneReport for Unigene cluster for ARL15 Gene Hs.659125

genes like me logo Genes that share expressions with ARL15: view

Orthologs for ARL15 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ARL15 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ARL15 36
  • 99.51 (n)
  • 100 (a)
ARL15 37
  • 96 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ARL15 36
  • 93.73 (n)
  • 97.52 (a)
ARL15 37
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ARL15 36
  • 95.26 (n)
  • 98.04 (a)
ARL15 37
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Arl15 36
  • 90.36 (n)
  • 97.06 (a)
Arl15 16
Arl15 37
  • 97 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ARL15 37
  • 84 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ARL15 37
  • 85 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Arl15 36
  • 88.83 (n)
  • 97.34 (a)
chicken
(Gallus gallus)
Aves ARL15 36
  • 85.79 (n)
  • 92.63 (a)
ARL15 37
  • 87 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ARL15 37
  • 87 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.15654 36
tropical clawed frog
(Silurana tropicalis)
Amphibia arl15 36
  • 79.51 (n)
  • 86.46 (a)
Str.3925 36
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.3759 36
zebrafish
(Danio rerio)
Actinopterygii arl15a 37
  • 67 (a)
OneToMany
arl15b 36
  • 73.12 (n)
  • 83.77 (a)
arl15b 37
  • 65 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea arl-13 37
  • 13 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ARL1 37
  • 32 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.3634 37
  • 13 (a)
ManyToMany
Species with no ortholog for ARL15:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ARL15 Gene

ENSEMBL:
Gene Tree for ARL15 (if available)
TreeFam:
Gene Tree for ARL15 (if available)

Paralogs for ARL15 Gene

Paralogs for ARL15 Gene

Selected SIMAP similar genes for ARL15 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ARL15: view

Variants for ARL15 Gene

Sequence variations from dbSNP and Humsavar for ARL15 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs2448 -- 54,006,524(+) AATCA(C/T)GCTGC intron-variant
rs2783 -- 54,194,044(+) TATGG(C/T)AGTGA intron-variant
rs25853 -- 54,188,388(-) CTTGT(A/G)TAGAA intron-variant
rs25854 -- 54,187,350(-) TGGAG(A/T)CAGGG intron-variant
rs25857 -- 54,046,905(+) GGGAA(G/T)GCCTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ARL15 Gene

Variant ID Type Subtype PubMed ID
nsv830298 CNV Gain 17160897
nsv880713 CNV Gain 21882294
nsv830299 CNV Gain 17160897
nsv880272 CNV Gain 21882294
dgv6066n71 CNV Gain 21882294
nsv881616 CNV Gain 21882294
dgv6067n71 CNV Gain 21882294
nsv328114 CNV Loss 16902084
nsv4829 CNV Insertion 18451855
esv2542415 CNV Deletion 19546169
esv997418 CNV Insertion 20482838
esv1766790 CNV Insertion 17803354
nsv329076 CNV Insertion 16902084
nsv823074 CNV Loss 20364138
esv7542 CNV Loss 19470904
esv2730185 CNV Deletion 23290073
esv2663755 CNV Deletion 23128226
nsv4830 CNV Loss 18451855
nsv524694 CNV Gain 19592680
dgv6068n71 CNV Gain 21882294
nsv329660 CNV Loss 16902084

Relevant External Links for ARL15 Gene

HapMap Linkage Disequilibrium report
ARL15

Disorders for ARL15 Gene

Relevant External Links for ARL15

Genetic Association Database (GAD)
ARL15
Human Genome Epidemiology (HuGE) Navigator
ARL15
genes like me logo Genes that share disorders with ARL15: view

No data available for UniProtKB/Swiss-Prot for ARL15 Gene

Publications for ARL15 Gene

  1. A genome-wide association study reveals variants in ARL15 that influence adiponectin levels. (PMID: 20011104) Richards J.B. … Spector T.D. (PLoS Genet. 2009) 3 23 49
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49

Products for ARL15 Gene

Sources for ARL15 Gene

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