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Aliases for ARL14EPL Gene

Aliases for ARL14EPL Gene

  • ADP Ribosylation Factor Like GTPase 14 Effector Protein Like 2 3 5
  • ADP-Ribosylation Factor Like GTPase 14 Effector Protein Like 2

External Ids for ARL14EPL Gene

Previous GeneCards Identifiers for ARL14EPL Gene

  • GC05U901645
  • GC05P115388

Summaries for ARL14EPL Gene

GeneCards Summary for ARL14EPL Gene

ARL14EPL (ADP Ribosylation Factor Like GTPase 14 Effector Protein Like) is a Protein Coding gene. An important paralog of this gene is ENSG00000268714.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARL14EPL Gene

Genomics for ARL14EPL Gene

Regulatory Elements for ARL14EPL Gene

Enhancers for ARL14EPL Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05F116031 1 Ensembl ENCODE 0.8 -0.1 -117 0.8 CTCF IRF2 ATF1 JUN RAD21 ZNF101 RARA RFX5 FOXK2 SCRT2 ENSG00000250015 CCT5P1 SEMA6A-AS1 ARL14EPL ENSG00000268714
GH05F116038 1 FANTOM5 Ensembl ENCODE 0.4 +6.4 6382 1.4 CTCF MTA2 RNF2 EBF1 RAD21 SPI1 LVRN ARL14EPL GC05M116052
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ARL14EPL on UCSC Golden Path with GeneCards custom track

Genomic Location for ARL14EPL Gene

116,032,324 bp from pter
116,060,118 bp from pter
27,795 bases
Plus strand

Genomic View for ARL14EPL Gene

Genes around ARL14EPL on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ARL14EPL Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ARL14EPL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARL14EPL Gene

Proteins for ARL14EPL Gene

  • Protein details for ARL14EPL Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    ARL14 effector protein-like
    Protein Accession:

    Protein attributes for ARL14EPL Gene

    152 amino acids
    Molecular mass:
    17712 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ARL14EPL Gene

Post-translational modifications for ARL14EPL Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ARL14EPL Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ARL14EPL Gene

Domains & Families for ARL14EPL Gene

Protein Domains for ARL14EPL Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ARL14EPL: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ARL14EPL Gene

Function for ARL14EPL Gene

Phenotypes for ARL14EPL Gene

GenomeRNAi human phenotypes for ARL14EPL:
genes like me logo Genes that share phenotypes with ARL14EPL: view

Animal Model Products

miRNA for ARL14EPL Gene

miRTarBase miRNAs that target ARL14EPL

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ARL14EPL Gene

Localization for ARL14EPL Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ARL14EPL Gene

Pathways & Interactions for ARL14EPL Gene

SuperPathways for ARL14EPL Gene

No Data Available

Interacting Proteins for ARL14EPL Gene

Gene Ontology (GO) - Biological Process for ARL14EPL Gene


No data available for Pathways by source and SIGNOR curated interactions for ARL14EPL Gene

Transcripts for ARL14EPL Gene

mRNA/cDNA for ARL14EPL Gene

(2) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ARL14EPL Gene

ADP-ribosylation factor-like 14 effector protein-like:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ARL14EPL Gene

No ASD Table

Relevant External Links for ARL14EPL Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ARL14EPL Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ARL14EPL Gene

NURSA nuclear receptor signaling pathways regulating expression of ARL14EPL Gene:


SOURCE GeneReport for Unigene cluster for ARL14EPL Gene:

genes like me logo Genes that share expression patterns with ARL14EPL: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ARL14EPL Gene

Orthologs for ARL14EPL Gene

This gene was present in the common ancestor of animals.

Orthologs for ARL14EPL Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ARL14EPL 34
  • 98.9 (n)
(Canis familiaris)
Mammalia ARL14EPL 34
  • 87.5 (n)
-- 35
  • 86 (a)
(Bos Taurus)
Mammalia ARL14EPL 34
  • 85.43 (n)
C10H11ORF46 35
  • 83 (a)
-- 35
  • 60 (a)
MGC134232 35
  • 60 (a)
(Mus musculus)
Mammalia Arl14epl 34 16 35
  • 84.21 (n)
(Rattus norvegicus)
Mammalia Arl14epl 34
  • 82.68 (n)
(Monodelphis domestica)
Mammalia -- 35
  • 77 (a)
-- 35
  • 63 (a)
-- 35
  • 35 (a)
-- 35
  • 16 (a)
-- 35
  • 6 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 52 (a)
(Gallus gallus)
Aves ARL14EPL 34
  • 65.53 (n)
-- 35
  • 53 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia arl14epl 34
  • 68.23 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG14464 35
  • 26 (a)
Species where no ortholog for ARL14EPL was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ARL14EPL Gene

Gene Tree for ARL14EPL (if available)
Gene Tree for ARL14EPL (if available)

Paralogs for ARL14EPL Gene

Paralogs for ARL14EPL Gene

(1) SIMAP similar genes for ARL14EPL Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ARL14EPL: view

Variants for ARL14EPL Gene

Sequence variations from dbSNP and Humsavar for ARL14EPL Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs10055082 -- 116,059,345(+) TAGTT(A/G)TCCTT downstream-variant-500B, utr-variant-3-prime
rs10060276 -- 116,049,719(+) CCATA(A/G)AAGAG upstream-variant-2KB
rs10064684 -- 116,059,184(+) ATCAG(A/C)ATTTC downstream-variant-500B, utr-variant-3-prime
rs10064742 -- 116,059,211(+) CTCTA(A/C)TCTGC downstream-variant-500B, utr-variant-3-prime
rs10077428 -- 116,058,287(+) CATTC(A/G)GCATA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ARL14EPL Gene

Variant ID Type Subtype PubMed ID
dgv10028n54 CNV gain 21841781
dgv5789n100 CNV gain 25217958
dgv5790n100 CNV loss 25217958
esv2763487 CNV gain 21179565
esv34146 CNV loss 18971310
nsv515611 CNV gain+loss 19592680
nsv527320 CNV loss 19592680
nsv968236 CNV duplication 23825009

Variation tolerance for ARL14EPL Gene

Gene Damage Index Score: 1.18; 23.71% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ARL14EPL Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ARL14EPL Gene

Disorders for ARL14EPL Gene

Relevant External Links for ARL14EPL

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ARL14EPL Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ARL14EPL Gene

Publications for ARL14EPL Gene

  1. The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J. … Rubin E.M. (Nature 2004) 4 64
  2. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PMID: 10737800) Dias Neto E. … Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3 64

Products for ARL14EPL Gene

Sources for ARL14EPL Gene

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