Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ARL13A Gene

Aliases for ARL13A Gene

  • ADP Ribosylation Factor Like GTPase 13A 2 3 5
  • ADP-Ribosylation Factor Like GTPase 13A 2 3
  • ADP-Ribosylation Factor-Like 13 2 3
  • ADP-Ribosylation Factor-Like 13A 3
  • DJ341D10.2 3
  • ARL13 3

External Ids for ARL13A Gene

Previous HGNC Symbols for ARL13A Gene

  • ARL13

Previous GeneCards Identifiers for ARL13A Gene

  • GC0XP100035
  • GC0XP100111
  • GC0XP100224
  • GC0XP090022

Summaries for ARL13A Gene

GeneCards Summary for ARL13A Gene

ARL13A (ADP Ribosylation Factor Like GTPase 13A) is a Protein Coding gene. Diseases associated with ARL13A include Joubert Syndrome With Orofaciodigital Defect and Joubert Syndrome 1. GO annotations related to this gene include GTP binding. An important paralog of this gene is ARL13B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARL13A Gene

Genomics for ARL13A Gene

Regulatory Elements for ARL13A Gene

Enhancers for ARL13A Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ARL13A on UCSC Golden Path with GeneCards custom track

Genomic Location for ARL13A Gene

100,969,040 bp from pter
100,990,831 bp from pter
21,792 bases
Plus strand

Genomic View for ARL13A Gene

Genes around ARL13A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ARL13A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ARL13A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARL13A Gene

Proteins for ARL13A Gene

  • Protein details for ARL13A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    ADP-ribosylation factor-like protein 13A
    Protein Accession:
    Secondary Accessions:
    • B2RTT6
    • B4DX50

    Protein attributes for ARL13A Gene

    290 amino acids
    Molecular mass:
    33003 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAI42661.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for ARL13A Gene


neXtProt entry for ARL13A Gene

Proteomics data for ARL13A Gene at MOPED

Post-translational modifications for ARL13A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ARL13A Gene

No data available for DME Specific Peptides for ARL13A Gene

Domains & Families for ARL13A Gene

Gene Families for ARL13A Gene

Protein Domains for ARL13A Gene

Suggested Antigen Peptide Sequences for ARL13A Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the small GTPase superfamily. Arf family.
  • Belongs to the small GTPase superfamily. Arf family.
genes like me logo Genes that share domains with ARL13A: view

Function for ARL13A Gene

Phenotypes for ARL13A Gene

genes like me logo Genes that share phenotypes with ARL13A: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ARL13A Gene

Localization for ARL13A Gene

Subcellular locations from

Jensen Localization Image for ARL13A Gene COMPARTMENTS Subcellular localization image for ARL13A gene
Compartment Confidence
extracellular 2
mitochondrion 2
cytosol 1
nucleus 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ARL13A Gene

Pathways & Interactions for ARL13A Gene

SuperPathways for ARL13A Gene

No Data Available

Interacting Proteins for ARL13A Gene

Gene Ontology (GO) - Biological Process for ARL13A Gene


No data available for Pathways by source and SIGNOR curated interactions for ARL13A Gene

Drugs & Compounds for ARL13A Gene

No Compound Related Data Available

Transcripts for ARL13A Gene

mRNA/cDNA for ARL13A Gene

(3) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ARL13A Gene

ADP-ribosylation factor-like 13A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ARL13A Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6
SP2: - - -

Relevant External Links for ARL13A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ARL13A Gene

mRNA expression in normal human tissues for ARL13A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ARL13A Gene

This gene is overexpressed in Testis (x31.9).

Protein differential expression in normal tissues from HIPED for ARL13A Gene

This gene is overexpressed in Liver, secretome (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ARL13A Gene

SOURCE GeneReport for Unigene cluster for ARL13A Gene Hs.147237

genes like me logo Genes that share expression patterns with ARL13A: view

Protein tissue co-expression partners for ARL13A Gene

- Elite partner

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for ARL13A Gene

Orthologs for ARL13A Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ARL13A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ARL13A 35
  • 74.66 (n)
  • 65.04 (a)
ARL13A 36
  • 42 (a)
(Canis familiaris)
Mammalia ARL13A 35
  • 82.2 (n)
  • 74.04 (a)
(Mus musculus)
Mammalia Arl13a 35
  • 75.4 (n)
  • 64.92 (a)
Arl13a 16
Arl13a 36
  • 42 (a)
(Pan troglodytes)
Mammalia ARL13A 35
  • 99.46 (n)
  • 99.6 (a)
ARL13A 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Arl13a 35
  • 77.42 (n)
  • 68.95 (a)
(Gallus gallus)
Aves ARL13A 36
  • 42 (a)
(Anolis carolinensis)
Reptilia ARL13A 36
  • 34 (a)
(Danio rerio)
Actinopterygii arl13a 36
  • 20 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG17819 36
  • 25 (a)
(Caenorhabditis elegans)
Secernentea Y54E10BR.2 36
  • 21 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ARL3 36
  • 26 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 29 (a)
Species with no ortholog for ARL13A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ARL13A Gene

Gene Tree for ARL13A (if available)
Gene Tree for ARL13A (if available)

Paralogs for ARL13A Gene

Paralogs for ARL13A Gene

(4) SIMAP similar genes for ARL13A Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ARL13A: view

Variants for ARL13A Gene

Sequence variations from dbSNP and Humsavar for ARL13A Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs748226583 -- 100,968,561(+) AACAC(A/G)TAACT upstream-variant-2KB
rs748316562 -- 100,970,468(+) AGCAA(A/C)GCCCA intron-variant
rs749843567 -- 100,970,071(+) AGGCT(C/T)TGCCA intron-variant
rs749921711 -- 100,967,491(+) AGCTA(C/T)TCAGA upstream-variant-2KB
rs2097516 -- 100,967,299(+) ACACC(A/G)TAAGA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ARL13A Gene

Variant ID Type Subtype PubMed ID
nsv7012 CNV Insertion 18451855
nsv517937 CNV Gain 19592680
nsv515758 CNV Gain 19592680

Variation tolerance for ARL13A Gene

Residual Variation Intolerance Score: 40.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.49; 55.24% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ARL13A Gene

Disorders for ARL13A Gene

MalaCards: The human disease database

(3) MalaCards diseases for ARL13A Gene - From: DISEASES

Disorder Aliases PubMed IDs
joubert syndrome with orofaciodigital defect
  • orofaciodigital syndrome vi
joubert syndrome 1
  • joubert syndrome
meckel syndrome 1
  • meckel syndrome
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for ARL13A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with ARL13A: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ARL13A Gene

Publications for ARL13A Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ARL13A Gene

Sources for ARL13A Gene