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Aliases for ARL10 Gene

Aliases for ARL10 Gene

  • ADP-Ribosylation Factor-Like 10 2 3
  • ADP-Ribosylation Factor-Like 10A 2 3
  • ARL10A 3 4
  • ADP-Ribosylation Factor-Like Membrane-Associated Protein 3
  • ADP-Ribosylation Factor-Like Protein 10 3

External Ids for ARL10 Gene

Previous Symbols for ARL10 Gene

  • ARL10A

Summaries for ARL10 Gene

GeneCards Summary for ARL10 Gene

ARL10 (ADP-Ribosylation Factor-Like 10) is a Protein Coding gene. GO annotations related to this gene include GTP binding. An important paralog of this gene is ARL1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARL10 Gene

Genomics for ARL10 Gene

Genomic Location for ARL10 Gene

Start:
176,365,468 bp from pter
End:
176,401,865 bp from pter
Size:
36,398 bases
Orientation:
Plus strand

Genomic View for ARL10 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ARL10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARL10 Gene

Regulatory Elements for ARL10 Gene

Proteins for ARL10 Gene

  • Protein details for ARL10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N8L6-ARL10_HUMAN
    Recommended name:
    ADP-ribosylation factor-like protein 10
    Protein Accession:
    Q8N8L6
    Secondary Accessions:

    Protein attributes for ARL10 Gene

    Size:
    244 amino acids
    Molecular mass:
    27459 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ARL10 Gene

Proteomics data for ARL10 Gene at MOPED

Post-translational modifications for ARL10 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys100

Other Protein References for ARL10 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ARL10 Gene

Domains for ARL10 Gene

Gene Families for ARL10 Gene

HGNC:
  • ARL :ADP-ribosylation factors-like
  • ARF :ADP-ribosylation factors

Protein Domains for ARL10 Gene

UniProtKB/Swiss-Prot:

ARL10_HUMAN
Family:
  • Belongs to the small GTPase superfamily. Arf family.:
    • Q8N8L6
genes like me logo Genes that share domains with ARL10: view

Function for ARL10 Gene

Gene Ontology (GO) - Molecular Function for ARL10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005525 GTP binding IEA --
genes like me logo Genes that share ontologies with ARL10: view

Phenotypes for ARL10 Gene

GenomeRNAi human phenotypes for ARL10:
genes like me logo Genes that share phenotypes with ARL10: view

miRNA for ARL10 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ARL10 Gene

Localization for ARL10 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ARL10 Gene COMPARTMENTS Subcellular localization image for ARL10 gene
Compartment Confidence
extracellular 2
endoplasmic reticulum 1
lysosome 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for ARL10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with ARL10: view

Pathways for ARL10 Gene

SuperPathways for ARL10 Gene

No Data Available

Interacting Proteins for ARL10 Gene

Gene Ontology (GO) - Biological Process for ARL10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006886 intracellular protein transport --
GO:0007264 small GTPase mediated signal transduction IEA --
genes like me logo Genes that share ontologies with ARL10: view

No data available for Pathways by source for ARL10 Gene

Transcripts for ARL10 Gene

Unigene Clusters for ARL10 Gene

ADP-ribosylation factor-like 10:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ARL10 Gene

No ASD Table

Relevant External Links for ARL10 Gene

GeneLoc Exon Structure for
ARL10
ECgene alternative splicing isoforms for
ARL10

Expression for ARL10 Gene

mRNA expression in normal human tissues for ARL10 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ARL10 Gene

SOURCE GeneReport for Unigene cluster for ARL10 Gene Hs.424552

genes like me logo Genes that share expressions with ARL10: view

Orthologs for ARL10 Gene

This gene was present in the common ancestor of animals.

Orthologs for ARL10 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ARL10 36
  • 98.36 (n)
  • 97.95 (a)
ARL10 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ARL10 37
  • 83 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ARL10 36
  • 91.27 (n)
  • 94.05 (a)
ARL10 37
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Arl10 36
  • 85.73 (n)
  • 86.01 (a)
Arl10 16
Arl10 37
  • 88 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ARL10 37
  • 60 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 28 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Arl10 36
  • 86.51 (n)
  • 88.69 (a)
chicken
(Gallus gallus)
Aves ARL10 36
  • 64.18 (n)
  • 51.32 (a)
ARL10 37
  • 48 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ARL10 37
  • 44 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia arl10 36
  • 51.91 (n)
  • 47.4 (a)
zebrafish
(Danio rerio)
Actinopterygii arl10 36
  • 55.02 (n)
  • 48.19 (a)
arl10 37
  • 43 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta Gie 37
  • 32 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea arl-8 37
  • 33 (a)
OneToMany
Species with no ortholog for ARL10:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ARL10 Gene

ENSEMBL:
Gene Tree for ARL10 (if available)
TreeFam:
Gene Tree for ARL10 (if available)

Paralogs for ARL10 Gene

Paralogs for ARL10 Gene

Selected SIMAP similar genes for ARL10 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ARL10: view

Variants for ARL10 Gene

Sequence variations from dbSNP and Humsavar for ARL10 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs1978602 -- 176,370,486(-) AGACA(A/T)ACAGT intron-variant
rs2303667 -- 176,365,602(-) CCGCC(C/G)AGCGC synonymous-codon, reference
rs4348234 -- 176,371,218(-) tttgt(A/C)ttttt intron-variant
rs7716378 -- 176,373,585(+) CGCAA(A/G)GAGGG downstream-variant-500B, utr-variant-3-prime
rs10214381 -- 176,371,942(+) GTTGT(A/C)CTGCT utr-variant-3-prime, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for ARL10 Gene

Variant ID Type Subtype PubMed ID
nsv462549 CNV Gain 19166990
esv2731167 CNV Deletion 23290073
esv2731168 CNV Deletion 23290073

Relevant External Links for ARL10 Gene

HapMap Linkage Disequilibrium report
ARL10

Disorders for ARL10 Gene

No disorders were found for ARL10 Gene.

No data available for UniProtKB/Swiss-Prot for ARL10 Gene

Publications for ARL10 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Rasl11a, member of a novel small monomeric GTPase gene family, is differentially expressed in prostate tumors. (PMID: 15033445) Louro R. … Reis E.M. (Biochem. Biophys. Res. Commun. 2004) 3 4
  3. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ARL10 Gene

Sources for ARL10 Gene

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