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Aliases for ARL10 Gene

Aliases for ARL10 Gene

  • ADP-Ribosylation Factor-Like 10 2 3
  • ADP-Ribosylation Factor-Like 10A 2 3
  • ARL10A 3 4
  • ADP-Ribosylation Factor-Like Membrane-Associated Protein 3

External Ids for ARL10 Gene

Previous HGNC Symbols for ARL10 Gene

  • ARL10A

Previous GeneCards Identifiers for ARL10 Gene

  • GC05P175726
  • GC05P175792
  • GC05P170718

Summaries for ARL10 Gene

GeneCards Summary for ARL10 Gene

ARL10 (ADP-Ribosylation Factor-Like 10) is a Protein Coding gene. GO annotations related to this gene include GTP binding. An important paralog of this gene is ARL1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARL10 Gene

Genomics for ARL10 Gene

Regulatory Elements for ARL10 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ARL10 Gene

Chromosome:
5
Start:
176,365,468 bp from pter
End:
176,415,463 bp from pter
Size:
49,996 bases
Orientation:
Plus strand

Genomic View for ARL10 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for ARL10 Gene

Proteins for ARL10 Gene

  • Protein details for ARL10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N8L6-ARL10_HUMAN
    Recommended name:
    ADP-ribosylation factor-like protein 10
    Protein Accession:
    Q8N8L6

    Protein attributes for ARL10 Gene

    Size:
    244 amino acids
    Molecular mass:
    27459 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ARL10 Gene

Proteomics data for ARL10 Gene at MOPED

Post-translational modifications for ARL10 Gene

  • Ubiquitination at Lys 100
  • Modification sites at PhosphoSitePlus

Other Protein References for ARL10 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ARL10 Gene

Domains & Families for ARL10 Gene

Gene Families for ARL10 Gene

Protein Domains for ARL10 Gene

Suggested Antigen Peptide Sequences for ARL10 Gene

Graphical View of Domain Structure for InterPro Entry

Q8N8L6

UniProtKB/Swiss-Prot:

ARL10_HUMAN :
  • Belongs to the small GTPase superfamily. Arf family.
Family:
  • Belongs to the small GTPase superfamily. Arf family.
genes like me logo Genes that share domains with ARL10: view

Function for ARL10 Gene

Gene Ontology (GO) - Molecular Function for ARL10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005525 GTP binding IEA --
genes like me logo Genes that share ontologies with ARL10: view
genes like me logo Genes that share phenotypes with ARL10: view

Animal Model Products

miRNA for ARL10 Gene

miRTarBase miRNAs that target ARL10

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ARL10

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for ARL10 Gene

Localization for ARL10 Gene

Gene Ontology (GO) - Cellular Components for ARL10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with ARL10: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for ARL10 Gene

Pathways & Interactions for ARL10 Gene

SuperPathways for ARL10 Gene

No Data Available

Interacting Proteins for ARL10 Gene

Gene Ontology (GO) - Biological Process for ARL10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006886 intracellular protein transport --
GO:0007264 small GTPase mediated signal transduction IEA --
genes like me logo Genes that share ontologies with ARL10: view

No data available for Pathways by source and SIGNOR curated interactions for ARL10 Gene

Drugs & Compounds for ARL10 Gene

No Compound Related Data Available

Transcripts for ARL10 Gene

Unigene Clusters for ARL10 Gene

ADP-ribosylation factor-like 10:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ARL10

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ARL10 Gene

No ASD Table

Relevant External Links for ARL10 Gene

GeneLoc Exon Structure for
ARL10
ECgene alternative splicing isoforms for
ARL10

Expression for ARL10 Gene

mRNA expression in normal human tissues for ARL10 Gene

Protein differential expression in normal tissues from HIPED for ARL10 Gene

This gene is overexpressed in Fetal Brain (45.7), Islet of Langerhans (13.9), and Frontal cortex (9.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ARL10 Gene



SOURCE GeneReport for Unigene cluster for ARL10 Gene Hs.424552

genes like me logo Genes that share expression patterns with ARL10: view

Protein tissue co-expression partners for ARL10 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ARL10 Gene

Orthologs for ARL10 Gene

This gene was present in the common ancestor of animals.

Orthologs for ARL10 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia ARL10 35
  • 91.27 (n)
  • 94.05 (a)
ARL10 36
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Arl10 35
  • 85.73 (n)
  • 86.01 (a)
Arl10 16
Arl10 36
  • 88 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ARL10 35
  • 98.36 (n)
  • 97.95 (a)
ARL10 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Arl10 35
  • 86.51 (n)
  • 88.69 (a)
cow
(Bos Taurus)
Mammalia ARL10 36
  • 83 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ARL10 36
  • 60 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 28 (a)
ManyToMany
chicken
(Gallus gallus)
Aves ARL10 35
  • 64.18 (n)
  • 51.32 (a)
ARL10 36
  • 48 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ARL10 36
  • 44 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia arl10 35
  • 51.91 (n)
  • 47.4 (a)
zebrafish
(Danio rerio)
Actinopterygii arl10 35
  • 55.02 (n)
  • 48.19 (a)
arl10 36
  • 43 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta Gie 36
  • 32 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea arl-8 36
  • 33 (a)
OneToMany
Species with no ortholog for ARL10:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ARL10 Gene

ENSEMBL:
Gene Tree for ARL10 (if available)
TreeFam:
Gene Tree for ARL10 (if available)

Paralogs for ARL10 Gene

Paralogs for ARL10 Gene

(19) SIMAP similar genes for ARL10 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ARL10: view

Variants for ARL10 Gene

Structural Variations from Database of Genomic Variants (DGV) for ARL10 Gene

Variant ID Type Subtype PubMed ID
nsv462549 CNV Gain 19166990
esv2731167 CNV Deletion 23290073
esv2731168 CNV Deletion 23290073

Variation tolerance for ARL10 Gene

Residual Variation Intolerance Score: 37.21% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.80; 16.91% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ARL10 Gene

HapMap Linkage Disequilibrium report
ARL10

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for ARL10 Gene

Disorders for ARL10 Gene

Relevant External Links for ARL10

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ARL10
genes like me logo Genes that share disorders with ARL10: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ARL10 Gene

Publications for ARL10 Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  3. Rasl11a, member of a novel small monomeric GTPase gene family, is differentially expressed in prostate tumors. (PMID: 15033445) Louro R. … Reis E.M. (Biochem. Biophys. Res. Commun. 2004) 67
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for ARL10 Gene

Sources for ARL10 Gene

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