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ARID3B Gene

protein-coding   GIFtS: 52
GCID: GC15P074833

AT Rich Interactive Domain 3B (BRIGHT-Like)

(Previous name: AT rich interactive domain 3B (BRIGHT- like))
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
AT Rich Interactive Domain 3B (BRIGHT-Like)1 2     Bright And Dead Ringer Protein2 3
BDP2 3 5     Bright-Like Protein2 3
DRIL22 3 5     ARID Domain-Containing Protein 3B2 3
AT Rich Interactive Domain 3B (BRIGHT- Like)1 2     AT-Rich Interactive Domain-Containing Protein 3B2

External Ids:    HGNC: 143501   Entrez Gene: 106202   Ensembl: ENSG000001793617   OMIM: 6124575   UniProtKB: Q8IVW63   

Export aliases for ARID3B gene to outside databases

Previous GC identifers: GC15P072549 GC15P072620 GC15P051630


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ARID3B Gene:
This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA-binding proteins. The encoded
protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse
Bright and Drosophila dead ringer proteins. A pseudogene on chromosome 1p31 exists for this gene. Members of the
ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional
regulation and possibly in chromatin structure modification. (provided by RefSeq, Jul 2008)

GeneCards Summary for ARID3B Gene:
ARID3B (AT rich interactive domain 3B (BRIGHT-like)) is a protein-coding gene. Diseases associated with ARID3B include intestinal atresia, and imperforate anus. An important paralog of this gene is ARID1B.

UniProtKB/Swiss-Prot: ARI3B_HUMAN, Q8IVW6
Function: Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors
nuclear targeting of ARID3A

Gene Wiki entry for ARID3B Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000015.10  NT_010194.18  NC_018926.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ARID3B gene promoter:
         AhR   STAT1   NF-1   STAT4   STAT1beta   STAT5A   STAT1alpha   AREB6   STAT2   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidARID3B promoter sequence
   Search Chromatin IP Primers for ARID3B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ARID3B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q24   Ensembl cytogenetic band:  15q24.1   HGNC cytogenetic band: 15q24

ARID3B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARID3B gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P074833:  view genomic region     (about GC identifiers)

Start:
74,833,518 bp from pter      End:
74,890,472 bp from pter
Size:
56,955 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: ARI3B_HUMAN, Q8IVW6 (See protein sequence)
Recommended Name: AT-rich interactive domain-containing protein 3B  
Size: 561 amino acids; 60637 Da
Subunit: Heterodimer with ARID3A. Interacts with unphosphorylated RB1
Sequence caution: Sequence=BAD92067.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: O95443 Q59HC9 Q6P9C9
Alternative splicing: 3 isoforms:  Q8IVW6-1   Q8IVW6-3   Q8IVW6-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ARID3B: NX_Q8IVW6

Explore proteomics data for ARID3B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ARID3B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_006456.1  
    ENSEMBL proteins: 
     ENSP00000343126   ENSP00000455668  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR023334 REKLES_domain
     IPR001606 ARID/BRIGHT_DNA-bd

    Graphical View of Domain Structure for InterPro Entry Q8IVW6

    ProtoNet protein and cluster: Q8IVW6

    1 Blocks protein domain: IPB001606 ARID (AT-rich interaction domain) protein

    UniProtKB/Swiss-Prot: ARI3B_HUMAN, Q8IVW6
    Similarity: Contains 1 ARID domain
    Similarity: Contains 1 REKLES domain


    ARID3B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ARI3B_HUMAN, Q8IVW6
    Function: Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors
    nuclear targeting of ARID3A

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding NAS10446990
         
    ARID3B for ontologies           About GeneDecksing


    Phenotypes:
         8 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Arid3b):
     cardiovascular system  cellular  craniofacial  embryogenesis  growth/size/body 
     mortality/aging  nervous system  normal 

    ARID3B for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Arid3btm1Take for ARID3B

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ARID3B
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ARID3B
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ARID3B

    miRNA
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    miRTarBase miRNAs that target ARID3B:
    hsa-mir-125a-5p (MIRT005419), hsa-let-7a-5p (MIRT052506), hsa-mir-181d-5p (MIRT041182), hsa-mir-26b-5p (MIRT029972), hsa-mir-335-5p (MIRT018595), hsa-mir-125b-5p (MIRT006719), hsa-let-7f-5p (MIRT051363), hsa-let-7b-5p (MIRT052058)

    Block miRNA regulation of human, mouse, rat ARID3B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ARID3B (see all 65):
    hsa-miR-193a-3p hsa-miR-330-5p hsa-let-7d hsa-miR-128 hsa-miR-219-5p hsa-miR-4275 hsa-let-7g hsa-miR-9
    SwitchGear 3'UTR luciferase reporter plasmidARID3B 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ARID3B

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    OriGene clones in human, mouse for ARID3B (see all 6)
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    GenScript: all cDNA clones in your preferred vector: ARID3B (NM_006465)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ARID3B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARID3B

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARID3B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ARI3B_HUMAN, Q8IVW6: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus NAS10446990
    GO:0005730NOT nucleolus IDA--

    ARID3B for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ARID3B
    Interactions:

        GeneGlobe Interaction Network for ARID3B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ARID3B (Q8IVW63 ENSP000003431264) via UniProtKB, MINT, STRING, and/or I2D (see all 38)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000206454Q018603, ENSP000003730164I2D: score=3 STRING: ENSP00000373016
    ENSG00000229094Q018603, ENSP000003888424I2D: score=3 STRING: ENSP00000388842
    ENSG00000230336Q018603, ENSP000004000474I2D: score=3 STRING: ENSP00000400047
    ENSG00000233911Q018603, ENSP000003928774I2D: score=3 STRING: ENSP00000392877
    ENSG00000235068Q018603, ENSP000004050414I2D: score=3 STRING: ENSP00000405041
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--
    GO:0008150biological_process ND--

    ARID3B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ARID3B (ARI3B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ARID3B gene: 
    NM_006465.2  

    Unigene Cluster for ARID3B:

    AT rich interactive domain 3B (BRIGHT-like)
    Hs.655532  [show with all ESTs]
    Unigene Representative Sequence: AB208830
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000346246(uc002ayd.3 uc002aye.3 uc010bjs.1) ENST00000569680(uc002ayc.3)
    ENST00000566147 ENST00000566468 ENST00000563567
    miRNA
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    Block miRNA regulation of human, mouse, rat ARID3B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ARID3B (see all 65):
    hsa-miR-193a-3p hsa-miR-330-5p hsa-let-7d hsa-miR-128 hsa-miR-219-5p hsa-miR-4275 hsa-let-7g hsa-miR-9
    SwitchGear 3'UTR luciferase reporter plasmidARID3B 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for ARID3B
    Predesigned siRNA for gene silencing in human, mouse, rat ARID3B
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    OriGene clones in human, mouse for ARID3B (see all 6)
    OriGene ORF clones in mouse, rat for ARID3B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ARID3B (NM_006465)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ARID3B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARID3B
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for ARID3B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ARID3B
      QuantiTect SYBR Green Assays in human, mouse, rat ARID3B
      QuantiFast Probe-based Assays in human, mouse, rat ARID3B

    Additional mRNA sequence: 

    AB208830.1 AF116846.1 AK298716.1 AK302034.1 AL137417.1 BC041792.1 BC045545.1 

    6 DOTS entries:

    DT.411085  DT.97763441  DT.101976390  DT.121015166  DT.91978191  DT.102829206 

    Selected AceView cDNA sequences (see all 86):

    BF509827 AW168390 CA449351 AA515479 AA306227 CR621500 AW674283 BM703620 
    BF592776 AJ713835 BX327319 AI056203 BI766046 BC041792 AI221989 BP430638 
    BX283109 BQ069452 BU632760 AI911119 CA502983 AA464091 AI671552 AF116846 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ARID3B (see all 6)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12
    SP1:                                                                                                
    SP2:                                                                                                
    SP3:                          -     -                                                               
    SP4:                                                                                                
    SP5:                                                                                                


    ECgene alternative splicing isoforms for ARID3B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ARID3B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTCTCGAATG
    ARID3B Expression
    About this image


    ARID3B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 7 entries
             C2a
             ESI-051   
     
     NULL (Uncategorized)
             Mesenchymal Progenitor Cells - Passage 2
    ARID3B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ARID3B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.655532

    UniProtKB/Swiss-Prot: ARI3B_HUMAN, Q8IVW6
    Tissue specificity: Expressed in placenta, testis and leukocytes. Expressed in neuroblastoma. Present in K-562
    erythrocytic leukemia cell line (at protein level)

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARID3B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ARID3B gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Arid3b1 , 5 AT rich interactive domain 3B (BRIGHT-like)1, 5 87.54(n)1
    87.1(a)1
      9 (31.56 cM)5
    563801  NM_019689.21  NP_062663.11 
     577903535 
    chicken
    (Gallus gallus)
    Aves ARID3B1 AT rich interactive domain 3B (BRIGHT-like) 76.38(n)
    74.48(a)
      100859297  NM_001256157.1  NP_001243086.1 
    lizard
    (Anolis carolinensis)
    Reptilia ARID3B6
    AT rich interactive domain 3B (BRIGHT-like)
    71(a)
    1 ↔ 1
    GL343721.1(211265-241671)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC1004964841 AT-rich interactive domain-containing protein 3B-like 61.64(n)
    61.22(a)
      100496484  XM_004916003.1  XP_004916060.1 
    zebrafish
    (Danio rerio)
    Actinopterygii arid3b6
    AT rich interactive domain 3B (Bright like)
    45(a)
    1 ↔ 1
    25(29854664-30046114) ENSDARG00000070474
    fruit fly
    (Drosophila melanogaster)
    Insecta retn6
    retained
    20(a)
    1 → many
    2R(19520135-19542343)
    worm
    (Caenorhabditis elegans)
    Secernentea cfi-16
    Protein CFI-1 (cfi-1) mRNA, complete cds
    34(a)
    1 → many
    I(9994731-9999928) WBGene00000476


    ENSEMBL Gene Tree for ARID3B (if available)
    TreeFam Gene Tree for ARID3B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ARID3B gene
    ARID1B2  ARID3C2  ARID1A2  ARID3A2  
    2 SIMAP similar genes for ARID3B using alignment to 2 protein entries:     ARI3B_HUMAN (see all proteins):
    ARID3A    ARID3C

    ARID3B for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for ARID3B
    PGOHUM00000244775


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ARID3B (see all 1030)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1425896031,2
    --54882502(+) TTTTGG/TTTTTG 1 -- us2k10--------
    rs1928587321,2
    --54882525(+) GCTCTC/GTCACC 1 -- us2k10--------
    rs561940261,2
    --54882557(+) GATCTC/TGGCTA 1 -- us2k10--------
    rs124390541,2
    C,H--74831552(+) cctccA/Gccgtc 1 -- us2k11Minor allele frequency- G:0.00NA 2
    rs1497372951,2
    --74831677(+) GCCAGA/GCTGGT 1 -- us2k10--------
    rs1848403731,2
    C--74831699(+) GACCTC/GGTGAT 1 -- us2k10--------
    rs1879946021,2
    --74832058(+) AGGCCA/GAGGCG 1 -- us2k10--------
    rs1808222231,2
    --74832241(+) GCTGAA/GGTTGC 1 -- us2k10--------
    rs558240911,2
    C--74832246(+) GGTTGT/CGCCAC 1 -- us2k11Minor allele frequency- C:0.00NA 2
    rs1443847281,2
    C--74832337(+) TTTTT-/TGGGGG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ARID3B (74833518 - 74890472 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for ARID3B:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1046755CNV Insertion17803354
    nsv513433CNV Insertion21212237
    nsv1611CNV Insertion18451855
    nsv904380CNV Loss21882294
    nsv904379CNV Loss21882294
    nsv457204CNV Loss19166990
    nsv817698CNV Gain17921354

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612457    OMIM disorders: --

    9 diseases for ARID3B:    
    About MalaCards
    intestinal atresia    imperforate anus    gastroschisis    retinoblastoma
    brain cancer    neuroblastoma    ovarian cancer    breast cancer
    leukemia

    2 diseases from the University of Copenhagen DISEASES database for ARID3B:
    Intestinal atresia     Imperforate anus

    ARID3B for disorders           About GeneDecksing

    Genetic Association Database (GAD): ARID3B
    Human Genome Epidemiology (HuGE) Navigator: ARID3B (1 document)

    Export disorders for ARID3B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ARID3B gene, integrated from 10 sources (see all 24):
    (articles sorted by number of sources associating them with ARID3B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. Genome-wide association study identifies eight loci associated with blood pressure. (PubMed id 19430483)1, 4 Newton-Cheh C....Munroe P.B. (Nat. Genet. 2009)
    3. Bdp, a new member of a family of DNA-binding proteins, associates with the retinoblastoma gene product. (PubMed id 10446990)1, 2 Numata S.... Croce C.M. (Cancer Res. 1999)
    4. Epigenetic regulation of the neuroblastoma genes, Arid3b and Mycn. (PubMed id 22751132)1 Kobayashi K....Nishikawa S.I. (Oncogene 2013)
    5. The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. (PubMed id 23667531)1 Cox J.L....Rizzino A. (PLoS ONE 2013)
    6. miR-125b targets ARID3B in breast cancer cells. (PubMed id 22307404)1 Akhavantabasi S....Erson-Bensan A.E. (Cell Struct. Funct. 2012)
    7. ARID3B induces tumor necrosis factor alpha mediated apoptosis while a novel ARID3B splice form does not induce cell death. (PubMed id 22860069)1 Joseph S....Cowden Dahl K.D. (PLoS ONE 2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    9. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    10. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10620 HGNC: 14350 AceView: ARID3B Ensembl:ENSG00000179361 euGenes: HUgn10620
    ECgene: ARID3B H-InvDB: ARID3B

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ARID3B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ARID3B gene:
    Search GeneIP for patents involving ARID3B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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