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ARID3A Gene

protein-coding   GIFtS: 56
GCID: GC19P000926

AT Rich Interactive Domain 3A (BRIGHT-Like)

(Previous names: dead ringer-like 1 (Drosophila), AT rich interactive domain...)
(Previous symbol: DRIL1)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
AT Rich Interactive Domain 3A (BRIGHT-Like)1 2     Dead Ringer-Like 1 (Drosophila)1
DRIL11 2 3 5     BRIGHT2
Dead Ringer-Like Protein 12 3     ARID Domain-Containing 3A2
DRIL32 3     AT Rich Interactive Domain 3A (BRIGHT- Like) Protein2
E2FBP12 3     AT-Rich Interactive Domain-Containing Protein 3A2
ARID Domain-Containing Protein 3A2 3     Dead Ringer-Like 12
B-Cell Regulator Of IgH Transcription2 3     Bright3
E2F-Binding Protein 12 3     DRX3
AT Rich Interactive Domain 3A (BRIGHT- Like)1     

External Ids:    HGNC: 30311   Entrez Gene: 18202   Ensembl: ENSG000001160177   OMIM: 6032655   UniProtKB: Q998563   

Export aliases for ARID3A gene to outside databases

Previous GC identifers: GC19P000880 GC19P000877 GC19P000699


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ARID3A Gene:
This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found
by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family
members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional
regulation, and possibly in chromatin structure modification. (provided by RefSeq, Jul 2008)

GeneCards Summary for ARID3A Gene:
ARID3A (AT rich interactive domain 3A (BRIGHT-like)) is a protein-coding gene. GO annotations related to this gene include chromatin binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ARID1B.

UniProtKB/Swiss-Prot: ARI3A_HUMAN, Q99856
Function: Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1
pathway and in B-cell differentiation

Gene Wiki entry for ARID3A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NT_011295.12  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ARID3A gene promoter:
         p53   AP-2beta   AP-2gamma   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidARID3A promoter sequence
   Search Chromatin IP Primers for ARID3A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ARID3A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.3   Ensembl cytogenetic band:  19p13.3   HGNC cytogenetic band: 19p13.3

ARID3A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARID3A gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P000926:  view genomic region     (about GC identifiers)

Start:
925,781 bp from pter      End:
975,939 bp from pter
Size:
50,159 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ARI3A_HUMAN, Q99856 (See protein sequence)
Recommended Name: AT-rich interactive domain-containing protein 3A  
Size: 593 amino acids; 62889 Da
Subunit: Homodimer. Heterodimer with ARID3B. Interacts with E2F1. Interacts with GTF2I and BTK
Sequence caution: Sequence=AAW30734.1; Type=Frameshift; Positions=498;
2 PDB 3D structures from and Proteopedia for ARID3A:
2KK0 (3D)        4LJX (3D)    
Secondary accessions: Q5I858 Q6P9C6 Q8IZA7 Q8N4Z3

Explore the universe of human proteins at neXtProt for ARID3A: NX_Q99856

Explore proteomics data for ARID3A at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ARID3A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_005215.1  
    ENSEMBL proteins: 
     ENSP00000263620   ENSP00000464969  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR023334 REKLES_domain
     IPR001606 ARID/BRIGHT_DNA-bd

    Graphical View of Domain Structure for InterPro Entry Q99856

    ProtoNet protein and cluster: Q99856

    1 Blocks protein domain: IPB001606 ARID (AT-rich interaction domain) protein

    UniProtKB/Swiss-Prot: ARI3A_HUMAN, Q99856
    Similarity: Contains 1 ARID domain
    Similarity: Contains 1 REKLES domain


    Find genes that share domains with ARID3A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ARI3A_HUMAN, Q99856
    Function: Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1
    pathway and in B-cell differentiation
    Induction: By p53/TP53 following DNA damage

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003682chromatin binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0005515protein binding IPI19214191
    GO:0042803protein homodimerization activity IEA--
         
    Find genes that share ontologies with ARID3A           About GenesLikeMe


    Phenotypes:
         10 MGI mutant phenotypes (inferred from 1 allele(MGI details for Arid3a):
     cardiovascular system  cellular  embryogenesis  growth/size/body  hematopoietic system 
     immune system  integument  liver/biliary system  mortality/aging  normal 

    Find genes that share phenotypes with ARID3A           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Arid3atm1Pwt for ARID3A

       genOway: Develop your customized and physiologically relevant rodent model for ARID3A

    miRNA
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    miRTarBase miRNAs that target ARID3A:
    hsa-let-7d-5p (MIRT032173), hsa-mir-484 (MIRT041956), hsa-mir-425-3p (MIRT042421), hsa-mir-98-5p (MIRT027857), hsa-mir-30b-5p (MIRT023439), hsa-let-7b-5p (MIRT005059)

    Block miRNA regulation of human, mouse, rat ARID3A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ARID3A (see all 36):
    hsa-let-7d hsa-miR-1224-3p hsa-miR-30d hsa-let-7g hsa-miR-30a hsa-let-7a hsa-miR-4326 hsa-miR-3163
    SwitchGear 3'UTR luciferase reporter plasmidARID3A 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ARI3A_HUMAN, Q99856: Nucleus. Cytoplasm. Note=Shuttles between nucleus and cytoplasm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2
    golgi apparatus1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005794Golgi apparatus IDA--

    Find genes that share ontologies with ARID3A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ARID3A About    
    See pathways by source

    SuperPathContained pathways About
    1Direct p53 effectors
    Direct p53 effectors


    1 BioSystems Pathway for ARID3A
        Direct p53 effectors


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ARID3A
    Interactions:

        GeneGlobe Interaction Network for ARID3A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ARID3A (Q998561, 2, 3 ENSP000002636204) via UniProtKB, MINT, STRING, and/or I2D (see all 46)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BTKQ061871, 2, 3, ENSP000003081764EBI-5458244,EBI-624835 MINT-7230949 MINT-7230913 MINT-7230932 MINT-7230971 I2D: score=4 STRING: ENSP00000308176
    CD19P153912, ENSP000003134194MINT-7230949 MINT-7230932 MINT-7230971 STRING: ENSP00000313419
    IGHMP018712MINT-7230949 MINT-7230932 MINT-7230971
    E2F1Q010943, ENSP000003455714I2D: score=3 STRING: ENSP00000345571
    TP53P046373, ENSP000002693054I2D: score=2 STRING: ENSP00000269305
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated ----
    GO:0045944positive regulation of transcription from RNA polymerase II promoter IEA--

    Find genes that share ontologies with ARID3A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ARID3A (ARI3A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ARID3A gene: 
    NM_005224.2  

    Unigene Cluster for ARID3A:

    AT rich interactive domain 3A (BRIGHT-like)
    Hs.501296  [show with all ESTs]
    Unigene Representative Sequence: BC060828
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000585895 ENST00000263620(uc002lql.3) ENST00000592916 ENST00000592216
    ENST00000587532 ENST00000585733 ENST00000590251 ENST00000590749
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate ARID3A (see all 36):
    hsa-let-7d hsa-miR-1224-3p hsa-miR-30d hsa-let-7g hsa-miR-30a hsa-let-7a hsa-miR-4326 hsa-miR-3163
    SwitchGear 3'UTR luciferase reporter plasmidARID3A 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AY152547.1 AY845638.1 BC007077.1 BC033163.1 BC060828.1 U88047.1 

    7 DOTS entries:

    DT.207762  DT.75117523  DT.101981944  DT.102830987  DT.40127347  DT.95089286  DT.95262915 

    Selected AceView cDNA sequences (see all 56):

    AI343403 AW293801 BM915483 AW292247 U88047 BM560075 BG336181 NM_005224 
    R36384 BG481613 BE350191 CR598405 AI394608 BC007077 BP345080 AY152547 
    AA232770 BM728646 BX344903 BX349962 BG480658 AW604456 CF551949 AA371391 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ARID3A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TACACAGGAG
    ARID3A Expression
    About this image


    ARID3A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Ovary (Reproductive System)    fully expand to see all 3 entries
             Secondary Follicle
     
     Peripheral Nervous System (Nervous System)
             Schwann Precursor Cells Peripheral Nerve Domain
     
     Limb (Muscoskeletal System)
             Limb Bud Mesenchyme Cells Limb Bud
     
     Blood (Hematopoietic System)
             Granulocytes Peripheral Blood
     
     Mesoderm (Gastrulation Derivatives)
             Limb Bud Mesenchyme Cells Limb Bud
    ARID3A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ARID3A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.501296

    UniProtKB/Swiss-Prot: ARI3A_HUMAN, Q99856
    Tissue specificity: Widely expressed, with highest expression in skeletal muscle, thalamus, and colon

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ARID3A gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Arid3a1 , 5 AT rich interactive domain 3A (BRIGHT-like)1, 5 78.89(n)1
    81.49(a)1
      10 (39.72 cM)5
    134961  NM_007880.31  NP_031906.11 
     799270435 
    chicken
    (Gallus gallus)
    Aves ARID3A1 AT rich interactive domain 3A (BRIGHT-like) 73.54(n)
    69.41(a)
      100858440  XM_003642870.2  XP_003642918.2 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.266942 Xenopus laevis transcribed sequence with moderate similarity more 79.5(n)    BJ065941.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5627991 AT-rich interactive domain-containing protein 3A-like 71(n)
    74.28(a)
      562799  XM_686173.6  XP_691265.5 
    fruit fly
    (Drosophila melanogaster)
    Insecta retn6
    retained
    20(a)
    1 → many
    2R(19520135-19542343)
    worm
    (Caenorhabditis elegans)
    Secernentea cfi-16
    Protein CFI-1 (cfi-1) mRNA, complete cds
    35(a)
    1 → many
    I(9994731-9999928) WBGene00000476


    ENSEMBL Gene Tree for ARID3A (if available)
    TreeFam Gene Tree for ARID3A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ARID3A gene
    ARID1B2  ARID3C2  ARID1A2  ARID3B2  
    3 SIMAP similar genes for ARID3A using alignment to 2 protein entries:     ARI3A_HUMAN (see all proteins):
    ARID3B    ARID3C    ARID1B

    Find genes that share paralogs with ARID3A           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ARID3A (see all 1360)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs97892911,2
    C--902738(+) AAAAAA/CAAAAA 1 -- ut310--------
    rs118816411,2
    C,F,H--924065(+) CCTTTC/TGGGTC 1 -- us2k13Minor allele frequency- T:0.11NA CSA WA 124
    rs1434892081,2
    --924074(+) TCTGCC/TGGCCT 1 -- us2k10--------
    rs3501361,2
    C,F,A--924131(+) CTGAGT/CTGGGT 1 -- us2k113Minor allele frequency- C:0.30MN NA WA CSA EA 559
    rs1833537181,2
    --924165(+) CCACAA/CCCCTT 1 -- us2k10--------
    rs1125413781,2
    F--924183(+) CTGCAG/CGGAGC 1 -- us2k11Minor allele frequency- C:0.50CSA 2
    rs1483576131,2
    --924229(+) CTCAGC/GCCTCT 1 -- us2k10--------
    rs1415312741,2
    C--924240(+) CCATCA/GGAGAT 1 -- us2k10--------
    rs129854851,2
    C,F--924245(+) GGAGAT/CAGGGG 1 -- us2k1 tfbs39Minor allele frequency- C:0.35NA WA EA 370
    rs3501371,2
    C,F,A,H--924362(+) CTTGTG/TGTCGG 1 -- us2k122Minor allele frequency- T:0.23NS EA NA WA CSA 2347

    HapMap Linkage Disequilibrium report for ARID3A (925781 - 975939 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for ARID3A (see all 35):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2665746CNV Deletion23128226
    esv3453CNV Deletion18987735
    esv2717813CNV Deletion23290073
    esv1501734CNV Deletion17803354
    esv2717811CNV Deletion23290073
    esv2717812CNV Deletion23290073
    esv2673891CNV Deletion23128226
    dgv3561n71CNV Loss21882294
    dgv3550n71CNV Loss21882294
    dgv3565n71CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603265    OMIM disorders: --


    Find genes that share disorders with ARID3A           About GenesLikeMe

    Genetic Association Database (GAD): ARID3A
    Human Genome Epidemiology (HuGE) Navigator: ARID3A (1 document)

    Export disorders for ARID3A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ARID3A gene, integrated from 10 sources (see all 41):
    (articles sorted by number of sources associating them with ARID3A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The human dead ringer/bright homolog, DRIL1: cDNA cloning, gene structure, and mapping to D19S886, a marker on 19p13.3 that is strictly linked to the Peutz-Jeghers syndrome. (PubMed id 9722953)1, 2, 3 Kortschak R.D....Jenne D.E. (Genomics 1998)
    2. A genome-wide association study of optic disc parameters. (PubMed id 20548946)1, 4 Ramdas W.D....van Duijn C.M. (PLoS Genet. 2010)
    3. Solution NMR structure of the ARID domain of human AT-rich interactive domain-containing protein 3A: a human cancer protein interaction network target. (PubMed id 20455271)1, 2 Liu G.... Montelione G.T. (Proteins 2010)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    6. Induction of immunoglobulin heavy-chain transcription through the transcription factor Bright requires TFII-I. (PubMed id 16738337)1, 2 Rajaiya J....Webb C.F. (Mol. Cell. Biol. 2006)
    7. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (Nature 2004)
    8. E2FBP1/DRIL1, an AT-rich interaction domain-family transcription factor, is regulated by p53. (PubMed id 12692263)1, 2 Ma K....Ikeda M.-A. (Mol. Cancer Res. 2003)
    9. A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence. (PubMed id 11812999)1, 2 Peeper D.S.... Bernards R. (Nat. Cell Biol. 2002)
    10. A novel E2F binding protein with Myc-type HLH motif stimulates E2F- dependent transcription by forming a heterodimer. (PubMed id 9780002)1, 2 Suzuki M.... Oda K. (Oncogene 1998)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 1820 HGNC: 3031 AceView: ARID3A Ensembl:ENSG00000116017 euGenes: HUgn1820
    ECgene: ARID3A H-InvDB: ARID3A

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ARID3A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ARID3A gene:
    Search GeneIP for patents involving ARID3A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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