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ARID2 Gene

protein-coding   GIFtS: 50
GCID: GC12P046123

AT Rich Interactive Domain 2 (ARID, RFX-Like)

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
AT Rich Interactive Domain 2 (ARID, RFX-Like)1 2     p2002
Zinc Finger Protein With Activation Potential2 3     zipzap2
BAF2002 3     zipzap/p2002
ARID Domain-Containing Protein 22 3     KIAA15573
BRG1-Associated Factor 2002 3     Zipzap/p2003
AT-Rich Interactive Domain-Containing Protein 22     

External Ids:    HGNC: 180371   Entrez Gene: 1965282   Ensembl: ENSG000001890797   OMIM: 6095395   UniProtKB: Q68CP93   

Export aliases for ARID2 gene to outside databases

Previous GC identifers: GC12P044410 GC12P044411 GC12P044408 GC12P043152


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ARID2 Gene:
ARID2 is a subunit of the PBAF chromatin-remodeling complex (see BAF180; MIM 606083), which facilitates
ligand-dependent transcriptional activation by nuclear receptors (Yan et al., 2005 (PubMed 15985610)).(supplied
by OMIM, Mar 2008)

GeneCards Summary for ARID2 Gene:
ARID2 (AT rich interactive domain 2 (ARID, RFX-like)) is a protein-coding gene.

UniProtKB/Swiss-Prot: ARID2_HUMAN, Q68CP9
Function: Involved in transcriptional activation and repression of select genes by chromatin remodeling
(alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex
SWI/SNF-B (PBAF). May be involved in targeting the complex to different genes. May be involved in regulating
transcriptional activation of cardiac genes

Gene Wiki entry for ARID2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NT_029419.13  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ARID2 gene promoter:
         Nkx2-5   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidARID2 promoter sequence
   Search Chromatin IP Primers for ARID2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ARID2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q12   Ensembl cytogenetic band:  12q12   HGNC cytogenetic band: 12q13.11

ARID2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARID2 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P046123:  view genomic region     (about GC identifiers)

Start:
46,123,448 bp from pter      End:
46,301,823 bp from pter
Size:
178,376 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ARID2_HUMAN, Q68CP9 (See protein sequence)
Recommended Name: AT-rich interactive domain-containing protein 2  
Size: 1835 amino acids; 197391 Da
Subunit: Component of the SWI/SNF-B (PBAF) chromatin remodeling complex, at least composed of SMARCA4/BRG1,
SMARCB1/BAF47, ACTL6A/BAF53A or ACTL6B/BAF53B, SMARCE1/BAF57, SMARCD1/BAF60A, SMARCD2/BAF60B, perhaps
SMARCD3/BAF60C, SMARCC1/BAF155, SMARCC2/BAF170, PB1/BAF180, ARID2/BAF200, ARID1A/BAF250A or ARID1B/BAF250B and
actin. Interacts with SRF. Forms complexes with SRF and SRF cofactors MYOCD, NKX2-5 and SRFBP1
Developmental stage: Up-regulated in adult heart (at protein level)
Sequence caution: Sequence=AAU20329.2; Type=Miscellaneous discrepancy; Note=Differs from position 1094 onward for
unknown reason; Sequence=BAB55320.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAC87171.1; Type=Miscellaneous discrepancy; Note=Unlikely isoform. Cloning artifact;
Secondary accessions: Q15KG9 Q5EB51 Q645I3 Q6ZRY5 Q7Z3I5 Q86T28 Q96SJ6 Q9HCL5
Alternative splicing: 2 isoforms:  Q68CP9-1   Q68CP9-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ARID2: NX_Q68CP9

Explore proteomics data for ARID2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys7, Lys15, Lys62, Lys1731, Lys1777
  • Modification sites at PhosphoSitePlus

  • See ARID2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_689854.2  
    ENSEMBL proteins: 
     ENSP00000335044   ENSP00000415650   ENSP00000397307   ENSP00000388357  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    Selected InterPro protein domains (see all 6):
     IPR011991 WHTH_DNA-bd_dom
     IPR015880 Znf_C2H2-like
     IPR003150 DNA-bd_RFX
     IPR016024 ARM-type_fold
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q68CP9

    ProtoNet protein and cluster: Q68CP9

    1 Blocks protein domain: IPB001606 ARID (AT-rich interaction domain) protein

    UniProtKB/Swiss-Prot: ARID2_HUMAN, Q68CP9
    Similarity: Contains 1 ARID domain
    Similarity: Contains 1 C2H2-type zinc finger
    Similarity: Contains 1 RFX-type winged-helix DNA-binding domain


    Find genes that share domains with ARID2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ARID2_HUMAN, Q68CP9
    Function: Involved in transcriptional activation and repression of select genes by chromatin remodeling
    (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex
    SWI/SNF-B (PBAF). May be involved in targeting the complex to different genes. May be involved in regulating
    transcriptional activation of cardiac genes

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0005488binding ----
    GO:0005515protein binding IPI15985610
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with ARID2           About GenesLikeMe


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Arid2):
     homeostasis/metabolism  mortality/aging 

    Find genes that share phenotypes with ARID2           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ARID2
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    miRTarBase miRNAs that target ARID2:
    hsa-mir-424-3p (MIRT038009), hsa-mir-1 (MIRT001384), hsa-mir-15b-5p (MIRT046521), hsa-mir-155-5p (MIRT001569)

    Block miRNA regulation of human, mouse, rat ARID2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ARID2 (see all 146):
    hsa-miR-26a-2* hsa-miR-128 hsa-miR-3653 hsa-miR-3074-3p hsa-miR-138-2* hsa-miR-3921 hsa-miR-298 hsa-miR-208b
    SwitchGear 3'UTR luciferase reporter plasmidARID2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ARID2

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARID2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ARID2_HUMAN, Q68CP9: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IEA--

    Find genes that share ontologies with ARID2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ARID2
    Interactions:

        Search GeneGlobe Interaction Network for ARID2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ARID2 (Q68CP91, 3 ENSP000003350444) via UniProtKB, MINT, STRING, and/or I2D (see all 41)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMARCA4P515321, 3, ENSP000003507204EBI-637818,EBI-302489 I2D: score=2 STRING: ENSP00000350720
    SMARCB1Q128241, 3, ENSP000002631214EBI-637818,EBI-358419 I2D: score=2 STRING: ENSP00000263121
    SMARCE1Q969G31, 3, ENSP000003239674EBI-637818,EBI-455078 I2D: score=3 STRING: ENSP00000323967
    PBRM1Q86U861, 3, ENSP000003492134EBI-637818,EBI-637807 I2D: score=2 STRING: ENSP00000349213
    NFYCQ139523, ENSP000003966204I2D: score=3 STRING: ENSP00000396620
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006337nucleosome disassembly IDA8895581
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--
    GO:0016568chromatin modification IEA--

    Find genes that share ontologies with ARID2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ARID2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ARID2 gene: 
    NM_152641.2  

    Unigene Cluster for ARID2:

    AT rich interactive domain 2 (ARID, RFX-like)
    Hs.317304  [show with all ESTs]
    Unigene Representative Sequence: NM_152641
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000334344(uc001ros.1) ENST00000427628 ENST00000426776 ENST00000422737(uc001ror.3)
    ENST00000479608(uc009zkg.1 uc009zkh.1) ENST00000480128(uc001rot.1)
    ENST00000444670(uc001rou.1) ENST00000457135 ENST00000477947
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate ARID2 (see all 146):
    hsa-miR-26a-2* hsa-miR-128 hsa-miR-3653 hsa-miR-3074-3p hsa-miR-138-2* hsa-miR-3921 hsa-miR-298 hsa-miR-208b
    SwitchGear 3'UTR luciferase reporter plasmidARID2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ARID2
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    GenScript: all cDNA clones in your preferred vector: ARID2 (NM_004973)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARID2
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    OriGene qSTAR qPCR primer pairs in human, mouse for ARID2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ARID2
      QuantiTect SYBR Green Assays in human, mouse, rat ARID2
      QuantiFast Probe-based Assays in human, mouse, rat ARID2

    Additional mRNA sequence: 

    AB046777.1 AK027617.1 AK027718.1 AK055181.1 AK075385.1 AK127872.1 AL832200.1 AY727870.2 
    BC018661.1 BC038726.1 BC064625.1 BC090062.1 BX537879.1 BX648152.1 BX649133.1 CR749833.1 
    DQ096628.1 

    10 DOTS entries:

    DT.410547  DT.97821016  DT.95161710  DT.95161711  DT.101982215  DT.121174763  DT.100751751  DT.75177991 
    DT.40315927  DT.121174760 

    Selected AceView cDNA sequences (see all 130):

    BQ023782 BF511848 AI480273 AI699913 BI460021 BM453234 AI589867 AA428565 
    AK027718 AA564462 AI149846 AI916262 AB046777 BM683434 AK075385 AY727870 
    AW104509 T25744 AI698477 CA430884 BC064625 BC038726 AI357926 BM727324 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ARID2 (see all 7)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10a · 10b · 10c ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16 ^ 17 ^ 18 ^ 19 ^
    SP1:                                                                                            -     -                                                         
    SP2:                                                                                            -                                                               
    SP3:                                                                                            -     -                                                         
    SP4:                                                                                -           -     -                                                         
    SP5:                                -     -     -     -     -     -     -     -     -     -     -     -     -     -     -     -                                 

    ExUns: 20 ^ 21 ^ 22 ^ 23
    SP1:              -         
    SP2:              -         
    SP3:                        
    SP4:              -         
    SP5:              -         


    ECgene alternative splicing isoforms for ARID2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ARID2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ARID2 Expression
    About this image


    ARID2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Eye (Sensory Organs)
             Retina
     
     Testis (Reproductive System)
    ARID2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ARID2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.317304

    UniProtKB/Swiss-Prot: ARID2_HUMAN, Q68CP9
    Tissue specificity: Highly expressed in heart and testis

        Custom PCR Arrays for ARID2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARID2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ARID2 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Arid21 , 5 AT rich interactive domain 2 (ARID, RFX-like)1, 5 88.98(n)1
    92.45(a)1
      15 (52.37 cM)5
    770441  NM_175251.41  NP_780460.31 
     962875185 
    chicken
    (Gallus gallus)
    Aves ARID21 AT rich interactive domain 2 (ARID, RFX-like) 84.65(n)
    85.52(a)
      417804  XM_004937552.1  XP_004937609.1 
    lizard
    (Anolis carolinensis)
    Reptilia ARID26
    AT rich interactive domain 2 (ARID, RFX-like)
    84(a)
    1 ↔ 1
    5(53631039-53726913)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.65072 Xenopus laevis transcribed sequence with weak similarity more 84.44(n)    BX855483.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufi45a012 Transcribed sequences 87.04(n)    BI842038.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Bap1706
    Brahma associated protein 170kD
    24(a)
    1 ↔ 1
    2R(2524021-2529863)
    worm
    (Caenorhabditis elegans)
    Secernentea swsn-76
    Protein SWSN-7 (swsn-7) mRNA, complete cds
    26(a)
    1 ↔ 1
    II(8022650-8027756) WBGene00007433


    ENSEMBL Gene Tree for ARID2 (if available)
    TreeFam Gene Tree for ARID2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ARID2 gene

    Find genes that share paralogs with ARID2           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for ARID2
    PGOHUM00000239757


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ARID2 (see all 3057)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2014152291,2
    --46123723(+) GCAGAA/CCCGGG 1 -- int10--------
    rs2009139741,2
    C--46123799(+) GCTGAC/TAAGTG 1 -- int10--------
    rs1999086741,2
    --46123808(+) TGCGGC/GGCTTT 1 -- int10--------
    rs2015963541,2
    --46123854(+) GCGGTG/TGGTGG 2 V syn10--------
    rs2007753261,2
    C--46123914(+) GGATTC/TGCGAA 2 F syn10--------
    rs671332301,2
    C,F--46124413(+) GAAATG/AATCCC 1 -- int19Minor allele frequency- A:0.40WA NA CSA EA 368
    rs1881877521,2
    --46124734(+) CGATTA/GGTTAT 1 -- int10--------
    rs1931646251,2
    --46124835(+) ACACAC/GTGATT 1 -- int10--------
    rs1836054561,2
    --46124836(+) CACAGC/TGATTC 1 -- int10--------
    rs1890478561,2
    C--46124975(+) GTTCAA/GACAAC 1 -- int10--------

    HapMap Linkage Disequilibrium report for ARID2 (46123448 - 46301823 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for ARID2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2516965CNV Insertion19546169
    esv273302CNV Insertion20981092
    esv268062CNV Insertion20981092
    nsv832396CNV Loss17160897
    nsv832397CNV Loss17160897
    nsv899053CNV Loss21882294
    nsv899052CNV Loss21882294
    dgv508e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ARID2
    DNA2.0 Custom Variant and Variant Library Synthesis for ARID2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609539    OMIM disorders: --


    Find genes that share disorders with ARID2           About GenesLikeMe

    Genetic Association Database (GAD): ARID2

    Export disorders for ARID2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ARID2 gene, integrated from 10 sources (see all 37):
    (articles sorted by number of sources associating them with ARID2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease. (PubMed id 19668339)1, 4 Potkin S.G....Macciardi F. (PLoS ONE 2009)
    2. Zipzap/p200 is a novel zinc finger protein contributing to cardiac gene regulation. (PubMed id 16782067)1, 2 Zhang X.... Wei J.Y. (Biochem. Biophys. Res. Commun. 2006)
    3. DNA-binding properties of ARID family proteins. (PubMed id 15640446)1, 2 Patsialou A.... Moran E. (Nucleic Acids Res. 2005)
    4. PBAF chromatin-remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon- responsive genes. (PubMed id 15985610)1, 2 Yan Z.... Wang W. (Genes Dev. 2005)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Recent advances in understanding chromatin remodeling by SWI/SNF complexes. (PubMed id 12672490)1, 2 Martens J.A. and Winston F. (Curr. Opin. Genet. Dev. 2003)
    8. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10997877)1, 2 Nagase T.... Ohara O. (DNA Res. 2000)
    9. Recurrent inactivating mutations of ARID2 in non-small cell lung carcinoma. (PubMed id 23047306)1 Manceau G....Blons H. (Int. J. Cancer 2013)
    10. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 196528 HGNC: 18037 AceView: ARID2 Ensembl:ENSG00000189079 euGenes: HUgn196528
    ECgene: ARID2 H-InvDB: ARID2

    (According to HUGE)
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    HUGE: KIAA1557

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ARID2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ARID2 gene:
    Search GeneIP for patents involving ARID2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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