Aliases for ARID2 Gene
External Ids for ARID2 Gene
Previous GeneCards Identifiers for ARID2 Gene
ARID2 is a subunit of the PBAF chromatin-remodeling complex (see BAF180; MIM 606083), which facilitates ligand-dependent transcriptional activation by nuclear receptors (Yan et al., 2005 [PubMed 15985610]).[supplied by OMIM, Mar 2008]
GeneCards Summary for ARID2 Gene
ARID2 (AT Rich Interactive Domain 2 (ARID, RFX-Like)) is a Protein Coding gene. Diseases associated with ARID2 include urethra clear cell adenocarcinoma and urethra adenocarcinoma. Among its related pathways are Chromatin organization and RNA Polymerase I Promoter Opening. GO annotations related to this gene include binding.
UniProtKB/Swiss-Prot for ARID2 Gene
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). May be involved in targeting the complex to different genes. May be involved in regulating transcriptional activation of cardiac genes.