Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ARID1A Gene

protein-coding   GIFtS: 60
GCID: GC01P027022

AT Rich Interactive Domain 1A (SWI-Like)

(Previous names: SWI/SNF related, matrix associated, actin dependent regulator...)
(Previous symbols: C1orf4, SMARCF1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
AT Rich Interactive Domain 1A (SWI-Like)1 2     AT Rich Interactive Domain 1A (SWI- Like)1
C1orf41 2 3 5     SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of
Chromatin, Subfamily F, Member 11
SMARCF11 2 3     BAF250a2
B1202 3 5     BM0292
Osa Homolog 12 3     ELD2
BAF2502 3     MRD142
OSA12 3     P2702
ARID Domain-Containing Protein 1A2 3     AT-Rich Interactive Domain-Containing Protein 1A2
BRG1-Associated Factor 250a2 3     Brain Protein 1202
hELD2 3     Chromatin Remodeling Factor P2502
hOSA12 3     OSA1 Nuclear Protein2
SWI-Like Protein2 3     BAF250A3
SWI/SNF Complex Protein P2702 3     BRG1-Associated Factor 2503
SWI/SNF-Related, Matrix-Associated, Actin-Dependent Regulator Of Chromatin
Subfamily F Member 12 3
     

External Ids:    HGNC: 111101   Entrez Gene: 82892   Ensembl: ENSG000001177137   OMIM: 6030245   UniProtKB: O144973   

Export aliases for ARID1A gene to outside databases

Previous GC identifers: GC01P026627 GC01P026706 GC01P026895 GC01P025309


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ARID1A Gene:
This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are
thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The
encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for
transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains
that could be important for its function. First, it has a DNA-binding domain that can specifically bind an
AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus
of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the
protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its
targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different
isoforms have been found for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for ARID1A Gene: 
ARID1A (AT rich interactive domain 1A (SWI-like)) is a protein-coding gene. Diseases associated with ARID1A include arid1a-related coffin-siris syndrome, and coffin-siris syndrome, and among its related super-pathways are Development Ligand-dependent activation of the ESR1/AP-1 pathway and PGC1Alpha Pathway. GO annotations related to this gene include transcription coactivator activity and ligand-dependent nuclear receptor binding. An important paralog of this gene is ARID3C.

UniProtKB/Swiss-Prot: ARI1A_HUMAN, O14497
Function: Involved in transcriptional activation and repression of select genes by chromatin remodeling
(alteration of DNA-nucleosome topology). Binds DNA non-specifically. Also involved in vitamin D-coupled
transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by
vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1
gene. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the
neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a
stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become
committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic
neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit
mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are
exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific
complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent
neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for
dendrite growth (By similarity)

Gene Wiki entry for ARID1A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_004610.19  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ARID1A gene promoter:
         E2F-4   E2F-3a   AREB6   E2F-5   E2F   p53   E2F-1   E2F-2   Pax-4a   GATA-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): ARID1A promoter sequence
   Search SABiosciences Chromatin IP Primers for ARID1A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARID1A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p35.3   Ensembl cytogenetic band:  1p36.11   HGNC cytogenetic band: 1p36.1-p35

ARID1A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARID1A gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P027022:  view genomic region     (about GC identifiers)

Start:
27,022,522 bp from pter      End:
27,108,601 bp from pter
Size:
86,080 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ARI1A_HUMAN, O14497 (See protein sequence)
Recommended Name: AT-rich interactive domain-containing protein 1A  
Size: 2285 amino acids; 242045 Da
Subunit: Component of SWI/SNF chromatin remodeling complexes, in some of which it can be mutually exclusive with
ARID1B/BAF250B. Component of the BAF (SWI/SNF-A) complex, which includes at least actin (ACTB), ARID1A,
ARID1B/BAF250, SMARCA2, SMARCA4/BRG1/BAF190A, ACTL6A/BAF53, ACTL6B/BAF53B, SMARCE1/BAF57, SMARCC1/BAF155,
SMARCC2/BAF170, SMARCB1/SNF5/INI1, and one or more of SMARCD1/BAF60A, SMARCD2/BAF60B, or SMARCD3/BAF60C. In
muscle cells, the BAF complex also contains DPF3. Component of the SWI/SNF-B (PBAF) complex, at least composed of
SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, ACTL6A/BAF53A or ACTL6B/BAF53B, SMARCE1/BAF57, SMARCD1/BAF60A,
SMARCD2/BAF60B, perhaps SMARCD3/BAF60C, SMARCC1/BAF155, SMARCC2/BAF170, PB1/BAF180, ARID2/BAF200, ARID1A/BAF250A
or ARID1B/BAF250B and actin. Component of the SWI/SNF Brm complex, at least composed of SMARCA2/BRM/BAF190B,
SMARCB1/BAF47, ACTL6A/BAF53A or ACTL6B/BAF53B, SMARCE1/BAF57, BAF60 (one or more of SMARCD1/BAF60A,
SMARCD2/BAF60B, or SMARCD3/BAF60C), SMARCC1/BAF155, SMARCC2/BAF170, ARID1A/BAF250A, SIN3A, HDAC1, HDAC2, and
RBAP4. Component of the SWI/SNF complex Brg1(I), at least composed of SMARCA4/BRG1/BAF190A, SMARCB1/BAF47,
ACTL6A/BAF53A or ACTL6B/BAF53B, SMARCE1/BAF57, BAF60 (one or more of SMARCD1/BAF60A, SMARCD2/BAF60B, or
SMARCD3/BAF60C), SMARCC1/BAF155, SMARCC2/BAF170, ARID1A/BAF250A, SIN3A, and probably HDAC2 and RBAP4. Component
of the SWI/SNF Brg1(II), at least composed of SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, ACTL6A/BAF53A or
ACTL6B/BAF53B, SMARCE1/BAF57, SMARCC1/BAF155, SMARCC2/BAF170, ARID1A/BAF250A and probably HDAC2 and RBAP4.
Component of a SWI/SNF-like EPAFa complex, at least composed of SMARCA4/BRG1/BAF190A, SMARCB1/BAF47,
ACTL6A/BAF53A, SMARCE1/BAF57, SMARCD1/BAF60A, SMARCC1/BAF155, SMARCC2/BAF170, BAF250A and MLLT1/ENL. Component of
a SWI/SNF-like complex containing ARID1A/BAF250A and ARID1B/BAF250B. Interacts through its C-terminus with
SMARCA2/BRM/BAF190B and SMARCA4/BRG1/BAF190A. Component of the WINAC complex, at least composed of SMARCA2,
SMARCA4, SMARCB1, SMARCC1, SMARCC2, SMARCD1, SMARCE1, ACTL6A, BAZ1B/WSTF, ARID1A, SUPT16H, CHAF1A and TOP2B.
Interacts with SMARCC1/BAF155. Component of neural progenitors-specific chromatin remodeling complex (npBAF
complex) composed of at least, ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C,
SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170,
PHF10/BAF45A, ACTL6A/BAF53A and actin. Component of neuron-specific chromatin remodeling complex (nBAF complex)
composed of at least, ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B,
SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, DPF1/BAF45B, DPF3/BAF45C,
ACTL6B/BAF53B and actin (By similarity)
Subcellular location: Nucleus
Sequence caution: Sequence=AAF75765.1; Type=Frameshift; Positions=374; Sequence=AAG33967.1; Type=Frameshift;
Positions=872, 885; Sequence=BAA23269.1; Type=Frameshift; Positions=Several; Sequence=BAA83073.1; Type=Erroneous
gene model prediction; Sequence=BAA83073.1; Type=Frameshift; Positions=Several;
1 PDB 3D structure from and Proteopedia for ARID1A:
1RYU (3D)    
Secondary accessions: D3DPL1 Q53FK9 Q5T0W1 Q5T0W2 Q5T0W3 Q8NFD6 Q96T89 Q9BY33 Q9HBJ5 Q9UPZ1
Alternative splicing: 3 isoforms:  O14497-1   O14497-2   O14497-3   

Explore the universe of human proteins at neXtProt for ARID1A: NX_O14497

Explore proteomics data for ARID1A at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O14497

  • ARID1A Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ARID1A Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_006006.3  NP_624361.1  

    ENSEMBL proteins: 
     ENSP00000320485   ENSP00000387636   ENSP00000432473   ENSP00000363267   ENSP00000390317  
     ENSP00000432368   ENSP00000436692   ENSP00000442437  

    Human Recombinant Protein Products for ARID1A: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for ARID1A
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for ARID1A
    GenScript Custom Purified and Recombinant Proteins Services for ARID1A
    Novus Biologicals ARID1A Protein
    Novus Biologicals ARID1A Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ARID1A 

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000790nuclear chromatin IDA17363140
    GO:0005622intracellular ----
    GO:0005634nucleus TAS12200431
    GO:0005730NOT nucleolus IDA--
    GO:0016514SWI/SNF complex IDA11078522

    ARID1A for ontologies           About GeneDecksing



    ARID1A Antibody Products: 
    EMD Millipore Mono- and Polyclonal Antibodies for the study of ARID1A
    Browse R&D Systems for Antibodies
    Cell Signaling Technology (CST) Antibodies for ARID1A 
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ARID1A
    GenScript Custom Superior Antibodies Services for ARID1A
    Novus Biologicals ARID1A Antibodies
    Abcam antibodies for ARID1A
    Cloud-Clone Corp. Antibodies for ARID1A 
    Search ThermoFisher Antibodies for ARID1A
    LSBio Antibodies in human, mouse, rat for ARID1A 

    Assay Products for ARID1A: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ARID1A
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ARID1A
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ARID1A 
    Cloud-Clone Corp. CLIAs for ARID1A


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR021906 DUF3518
     IPR001606 ARID/BRIGHT_DNA-bd

    Graphical View of Domain Structure for InterPro Entry O14497

    ProtoNet protein and cluster: O14497

    1 Blocks protein domain: IPB001606 ARID (AT-rich interaction domain) protein

    UniProtKB/Swiss-Prot: ARI1A_HUMAN, O14497
    Similarity: Contains 1 ARID domain


    ARID1A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ARI1A_HUMAN, O14497
    Function: Involved in transcriptional activation and repression of select genes by chromatin remodeling
    (alteration of DNA-nucleosome topology). Binds DNA non-specifically. Also involved in vitamin D-coupled
    transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by
    vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1
    gene. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the
    neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a
    stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become
    committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic
    neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit
    mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are
    exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific
    complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent
    neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for
    dendrite growth (By similarity)

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding NAS10757798
    GO:0003713transcription coactivator activity NAS8804307
    GO:0005488binding ----
    GO:0005515protein binding IPI11780067
    GO:0016922ligand-dependent nuclear receptor binding IPI17363140
         
    ARID1A for ontologies           About GeneDecksing


    Phenotypes:
         11 MGI mutant phenotypes (inferred from 7 alleles(MGI details for Arid1a):
     cardiovascular system  embryogenesis  growth/size  hematopoietic system  homeostasis/metabolism 
     mortality/aging  muscle  nervous system  no phenotypic analysis  normal 
     vision/eye 

    ARID1A for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for ARID1A: Arid1atm2Zhwa Arid1atm1Zhwa Arid1atm1.2Zhwa

       inGenious Targeting Laboratory - Custom generated mouse model solutions for ARID1A 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ARID1A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ARID1A 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ARID1A 

    miRNA
    Products:
        
    miRTarBase miRNAs that target ARID1A:
    hsa-mir-1 (MIRT001385), hsa-mir-101 (MIRT004027)

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ARID1A
    8/74 QIAGEN miScript miRNA Assays for microRNAs that regulate ARID1A (see all 74):
    hsa-miR-3607-3p hsa-miR-485-3p hsa-miR-30d hsa-miR-30a hsa-miR-4274 hsa-miR-3613-3p hsa-miR-3148 hsa-miR-509-3-5p
    SwitchGear 3'UTR luciferase reporter plasmidARID1A 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ARID1A
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ARID1A

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ARID1A
    Sirion Biotech Customized adenovirus for overexpression of ARID1A

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for ARID1A (see all 10)
    OriGene ORF clones in mouse, rat for ARID1A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): ARID1A (NM_139135)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ARID1A
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ARID1A

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ARID1A
    Search LifeMap BioReagents cell lines for ARID1A
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARID1A


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ARID1A About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Development Ligand-dependent activation of the ESR1/AP-1 pathway
    Development Ligand-dependent activation of the ESR1/AP-1 pathway0.37
    Transcription Ligand-dependent activation of the ESR1/SP pathway0.37
    2PEDF Induced Signaling
    Glucocorticoid Receptor Signaling0.43
    3Prostate Cancer
    Prostate Cancer0.32
    4Chromatin Regulation / Acetylation
    Chromatin Regulation / Acetylation
    5AMPK Enzyme Complex Pathway
    AMPK Enzyme Complex Pathway

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    2 EMD Millipore Pathways for ARID1A
        Development Ligand-dependent activation of the ESR1/AP-1 pathway
    Transcription Ligand-dependent activation of the ESR1/SP pathway

    2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for ARID1A
        AMPK Enzyme Complex Pathway
    Glucocorticoid Receptor Signaling

    1 Cell Signaling Technology (CST) Pathway for ARID1A
        Chromatin Regulation / Acetylation

    2 GeneGo (Thomson Reuters) Pathways for ARID1A
        Transcription Ligand-dependent activation of the ESR1/SP pathway
    Development Ligand-dependent activation of the ESR1/AP-1 pathway

    1 BioSystems Pathway for ARID1A
        Prostate Cancer



    ARID1A for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ARID1A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/819 Interacting proteins for ARID1A (O144971, 2, 3 ENSP000003204854) via UniProtKB, MINT, STRING, and/or I2D (see all 819)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMARCA2P515311, 2, 3, ENSP000002657734EBI-637887,EBI-679562 MINT-7945693 I2D: score=4 STRING: ENSP00000265773
    SMARCD1Q96GM52, 3, ENSP000003784144MINT-7945693 MINT-7947479 I2D: score=3 STRING: ENSP00000378414
    HDAC1Q135472, 3, ENSP000003626494MINT-7945693 MINT-7947479 I2D: score=2 STRING: ENSP00000362649
    ADNPQ9H2P02, 3, ENSP000003429054MINT-7945693 MINT-7947479 I2D: score=1 STRING: ENSP00000342905
    SMARCB1Q128242, 3, ENSP000002631214MINT-7945693 MINT-7947479 I2D: score=1 STRING: ENSP00000263121
    About this table

    Gene Ontology (GO): 5/12 biological process terms (GO ID links to tree view) (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006325chromatin organization ----
    GO:0006337nucleosome disassembly IDA8895581
    GO:0006338chromatin remodeling IDA11726552
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006357regulation of transcription from RNA polymerase II promoter NAS8804307

    ARID1A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ARID1A (ARI1A)

    Search CenterWatch for drugs/clinical trials and news about ARID1A / ARI1A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ARID1A gene (3 alternative transcripts): 
    NM_006015.4  NM_139135.2  NM_018450.4  

    Unigene Cluster for ARID1A:

    AT rich interactive domain 1A (SWI-like)
    Hs.468972  [show with all ESTs]
    Unigene Representative Sequence: NM_006015
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000324856(uc001bmt.1 uc001bmu.1 uc001bmv.1 uc001bmx.1 uc009vsm.1 uc009vsn.1)
    ENST00000457599 ENST00000524572 ENST00000374152(uc001bmw.1) ENST00000430291
    ENST00000430799 ENST00000466382 ENST00000532781 ENST00000540690
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ARID1A
    8/74 QIAGEN miScript miRNA Assays for microRNAs that regulate ARID1A (see all 74):
    hsa-miR-3607-3p hsa-miR-485-3p hsa-miR-30d hsa-miR-30a hsa-miR-4274 hsa-miR-3613-3p hsa-miR-3148 hsa-miR-509-3-5p
    SwitchGear 3'UTR luciferase reporter plasmidARID1A 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ARID1A
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ARID1A
    Clone
    Products:
         
    OriGene clones in human, mouse for ARID1A (see all 10)
    OriGene ORF clones in mouse, rat for ARID1A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): ARID1A (NM_139135)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ARID1A
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ARID1A
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for ARID1A
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ARID1A
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARID1A
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARID1A

    Additional mRNA sequence: 

    AB001895.1 AB210022.1 AF219114.1 AF231056.1 AF265208.1 AF268913.1 AF521670.1 AK027442.1 
    AK027655.1 AK074940.1 AK223275.1 AK308363.1 BC112895.1 

    20 DOTS entries:

    DT.80101892  DT.100820491  DT.95099951  DT.100820498  DT.95374384  DT.95306771  DT.92002745  DT.121415986 
    DT.91909049  DT.95125016  DT.75100076  DT.91762934  DT.92424902  DT.95125881  DT.95137717  DT.95153174 
    DT.95251905  DT.95316675  DT.100872497  DT.121415980 

    24/408 AceView cDNA sequences (see all 408):

    CD679468 BF982213 AA365243 BQ676377 BQ020715 T89199 AA630543 BM990490 
    AI951352 AI457364 BU153701 W57548 AF521670 BM725341 BQ001162 AI693846 
    AA385744 AW008106 AW592462 BM713733 AK027467 AK074940 H16963 BM449662 

    GeneLoc Exon Structure

    5/13 Alternative Splicing Database (ASD) splice patterns (SP) for ARID1A (see all 13)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15a · 15b · 15c ^ 16 ^ 17a · 17b ^ 18 ^ 19a ·
    SP1:                                                                                                                                                            
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 19b · 19c · 19d ^ 20 ^ 21 ^ 22a · 22b ^ 23 ^ 24
    SP1:                                                      
    SP2:                                                      
    SP3:                                                      
    SP4:                                                      
    SP5:                                                      


    ECgene alternative splicing isoforms for ARID1A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ARID1A expression in normal human tissues (normalized intensities)      ARID1A embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTGAACCTA
    ARID1A Expression
    About this image


    ARID1A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/9 selected tissues (see all 9) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
             brain/midbrain   
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Metencephalon
     
     Eye (Sensory Organs)
             Retina
     
     Thymus (Hematopoietic System)
             Thymus
     
     Kidney (Urinary System)
             Metanephros

    See ARID1A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ARID1A

    SOURCE GeneReport for Unigene cluster: Hs.468972

    UniProtKB/Swiss-Prot: ARI1A_HUMAN, O14497
    Tissue specificity: Highly expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, and PBL,
    and at a much lower level in heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas

        SABiosciences Expression via Pathway-Focused PCR Arrays including ARID1A: 
              Polycomb & Trithorax Complexes in human mouse rat
              Epigenetic Chromatin Remodeling Factors in human mouse rat

    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for ARID1A
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ARID1A
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARID1A
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARID1A
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARID1A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ARID1A gene from 7/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Arid1a1 , 5 AT rich interactive domain 1A (SWI-like)1, 5 93.24(n)1
    96.67(a)1
      4 (66.25 cM)5
    937601  NM_001080819.11  NP_001074288.11 
     1336790085 
    chicken
    (Gallus gallus)
    Aves ARID1A1 AT rich interactive domain 1A (SWI-like) 72.2(n)
    76.93(a)
      419542  XM_417693.3  XP_417693.3 
    lizard
    (Anolis carolinensis)
    Reptilia ARID1A6
    AT rich interactive domain 1A (SWI-like)
    84(a)
    1 ↔ 1
    GL343488.1(48289-103487)
    African clawed frog
    (Xenopus laevis)
    Amphibia BX843931.12   -- 78.58(n)    BX843931.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.269312 Transcribed sequence with weak similarity to protein more 84.69(n)    CB357397.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta osa1 CG7467-PA 44.84(n)
    35.25(a)
      42130  NM_206506.1  NP_996228.1 
    worm
    (Caenorhabditis elegans)
    Secernentea let-5266
    Protein LET-526, isoform a
    19(a)
    1 → many
    I(5301518-5313926)


    ENSEMBL Gene Tree for ARID1A (if available)
    TreeFam Gene Tree for ARID1A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ARID1A gene
    ARID3C2  ARID1B2  ARID3A2  ARID3B2  
    2 SIMAP similar genes for ARID1A using alignment to 8 protein entries:     ARI1A_HUMAN (see all proteins):
    ARID1A variant protein    ARID1B

    ARID1A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1511 SNPs in ARID1A are shown (see all 1511)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0680234
    ----see VAR_0680232 G R mis40--------
    VAR_0646954
    ----see VAR_0646952 R K mis40--------
    VAR_0680214
    ----see VAR_0680212 R W mis40--------
    VAR_0646964
    ----see VAR_0646962 L P mis40--------
    rs612423101,2
    C--27031943(+) TTTTT-/CCCCCC 2 -- int10--------
    rs710078871,2
    C--27040892(+) TGTTT-/GTTT/GTTT
    GTTTGTTTGTTT
    TTGAG
    2 -- int11NA 2
    rs668842051,2
    C--27060835(+) GCTTC-/TTTTTT 2 -- int10--------
    rs351107871,2
    C--27065368(+) TTTTT-/TGAGAC 2 -- int11Minor allele frequency- T:0.00NA 2
    rs360875881,2
    C--27075119(+) TTTTT-/T/TT  
            
    GTCAG
    2 -- int11NA 2
    rs591355561,2
    C--27083055(+) AAAAA-/ACAAAA 2 -- int10--------

    HapMap Linkage Disequilibrium report for ARID1A (27022522 - 27108601 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for ARID1A:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv275548CNV Loss21479260
    nsv7523CNV Loss18451855


    Human Gene Mutation Database (HGMD): ARID1A

    Locus Specific Mutation Databases (LSDB): ARID1A
    5/10 SABiosciences Cancer Mutation PCR Assays for ARID1A (see all 10):
    Cosmic IdAA Change
    51453p.Q524*
    13835p.G945fs*23
    51425p.R1989*
    51223p.W1545*
    51222p.S1338fs*106
    1 SABiosciences qBiomarker Copy Number PCR Array containing ARID1A:
    Pancreatic Cancer
    SeqTarget long-range PCR primers for resequencing ARID1A
    DNA2.0 Custom Variant and Variant Library Synthesis for ARID1A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 603024    OMIM disorders: --

    UniProtKB/Swiss-Prot: ARI1A_HUMAN, O14497
  • Mental retardation, autosomal dominant 14 (MRD14) [MIM:614607]: A disease characterized by multiple
    congenital anomalies and mental retardation. Mental retardation is defined by significantly below average general
    intellectual functioning associated with impairments in adaptative behavior and manifested during the
    developmental period. MRD14 patients manifest developmental delay, abnormal corpus callosum, absent/hypoplastic
    fifth finger/toenails, sparse scalp hair, long eyelashes, and a coarse facial appearance with wide mouth, thick
    lips, and abnormal ears. Note=The disease is caused by mutations affecting the gene represented in this entry

  • 20/24 diseases for ARID1A (see all 24):    About MalaCards
    arid1a-related coffin-siris syndrome    coffin-siris syndrome    adenofibroma    glucocorticoid resistance
    adenosquamous carcinoma    cystadenoma    williams syndrome    endocervicitis
    fanconi's anemia    endometriosis    gastric adenocarcinoma    acute lymphoblastic leukemia
    mental retardation    lymphoblastic leukemia    anemia    neuroblastoma
    gastric cancer    ovarian cancer    leukemia    adenocarcinoma

    3 diseases from the University of Copenhagen DISEASES database for ARID1A:
    Endometriosis     Adenofibroma     Coffin-Siris syndrome

    ARID1A for disorders           About GeneDecksing


    Export disorders for ARID1A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ARID1A gene, integrated from 9 sources (see all 108):
    (articles sorted by number of sources associating them with ARID1A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and expression of a novel human cDNA containing CAG repeats. (PubMed id 9434167)1, 2, 3 Takeuchi T.... Ohtsuki Y. (1997)
    2. Characterization of mammalian orthologues of the Drosophila osa gene: cDNA cloning, expression, chromosomal localization, and direct physical interaction with Brahma chromatin-remodeling complex. (PubMed id 11318604)1, 2, 9 Kozmik Z.... Vlcek C. (2001)
    3. The human SWI-SNF complex protein p270 is an ARID family member with non-sequence-specific DNA binding activity. (PubMed id 10757798)1, 2, 9 Dallas P.B....Moran E. (2000)
    4. Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types. (PubMed id 22009941)1, 2 Jones S....Papadopoulos N. (2012)
    5. Mutations affecting components of the SWI/SNF complex cause Coffin- Siris syndrome. (PubMed id 22426308)1, 2 Tsurusaki Y....Matsumoto N. (2012)
    6. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    7. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    8. Two related ARID family proteins are alternative subunits of human SWI/SNF complexes. (PubMed id 15170388)1, 2 Wang X.... Moran E. (2004)
    9. Structure and DNA-binding sites of the SWI1 AT-rich interaction domain (ARID) suggest determinants for sequence-specific DNA recognition. (PubMed id 14722072)1, 2 Kim S.... Chen Y. (2004)
    10. Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner. (PubMed id 12665591)1, 2 Nie Z.... Wang W. (2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8289 HGNC: 11110 AceView: ARID1A Ensembl:ENSG00000117713 euGenes: HUgn8289
    ECgene: ARID1A H-InvDB: ARID1A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ARID1A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ARID1A gene:
    Search GeneIP for patents involving ARID1A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     Browse for Gene Knock-down Tools from EMD Millipore
     Browse Small Molecules at EMD Millipore
     Browse Purified and Recombinant Proteins at EMD Millipore
     Browse Kits and Assays available from EMD Millipore
     EMD Millipore Mono- and Polyclonal Antibodies for the study of ARID1A
     Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ARID1A  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for ARID1A  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for ARID1A  
     OriGene qSTAR qPCR primer pairs in human, mouse for ARID1A   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for ARID1A   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ARID1A   OriGene Custom Protein Services for ARID1A  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ARID1A
     QIAGEN SeqTarget long-range PCR primers for resequencing ARID1A
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARID1A
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ARID1A
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARID1A
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARID1A
     GenScript Custom Purified and Recombinant Proteins Services for ARID1A GenScript cDNA clones with any tag delivered in your preferred vector for ARID1A
     GenScript Custom Assay Services for ARID1A GenScript Custom Superior Antibodies Services for ARID1A
     GenScript Custom overexpressing Cell Line Services for ARID1A CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Antibodies & Assays for ARID1A 

     Regulatory tfbs in ARID1A promoter
     Search Chromatin IP Primers for ARID1A
     RT2 qPCR Primer Assay in human, mouse, rat ARID1A
     Search GNC Networks for ARID1A
     SABiosciences PCR Arrays including human, mouse, rat ARID1A
     Search Tocris compounds for ARID1A (ARI1A)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ARID1A antibodies
     ARID1A proteins
     ARID1A lysates
     Antibodies for ARID1A
     See all of Abcam's Antibodies, Kits and Proteins for ARID1A
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for ARID1A
     Antibodies for ARID1A
     ELISAs for ARID1A
     CLIAs for ARID1A
     Search LifeMap BioReagents cell lines for ARID1A
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARID1A
     SwitchGear 3'UTR luciferase reporter plasmids for ARID1A
     SwitchGear Promoter luciferase reporter plasmids for ARID1A
     Search ThermoFisher Antibodies for ARID1A
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ARID1A
     inGenious Targeting Laboratory - Custom generated mouse model solutions for ARID1A
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ARID1A
    Customized:
     lentivirus for stable overexpression
     lentivirus expression plasmids for stable overexpression
     adenovirus for overexpression of ARID1A
     LSBio Antibodies in human, mouse, rat for ARID1A
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ARID1A gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4