ARHGEF5 Gene
protein-coding GIFtS: 59
GCID: GC07P144052
|
|
Rho guanine nucleotide exchange factor (GEF) 5
| |
Aliases
for ARHGEF5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Rho Guanine Nucleotide Exchange Factor (GEF) 51 2 | | Oncogene TIM2 3 | | TIM1 2 3 5 | | Transforming Immortalized Mammary Oncogene2 3 | | GEF51 2 | | P60 TIM2 3 | | P601 2 | | Ephexin-33 | | TIM11 2 | | Rho Guanine Nucleotide Exchange Factor 52 | | Guanine Nucleotide Regulatory Protein TIM2 3 | | Ephexin-33 |
Export aliases for ARHGEF5 gene to outside databasesPrevious GC identifers: GC07P142309 GC07P143376 GC07P143454 GC07P143453 GC07P143428 GC07P143500 GC07P143683 GC07P138140 |
Summaries
for ARHGEF5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ARHGEF5:
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work throughG protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependentsignals. This protein may be involved in the control of cytoskeletal organization. (provided by RefSeq, Jul 2008)
Gene Wiki entry for ARHGEF5
|
Genomic Views
for ARHGEF5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007914.15 NT_079596.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ARHGEF5 gene promoter:
AML1a p53 NRSF form 1 XBP-1 NF-kappaB NRSF form 2 c-Ets-1 FOXJ2 (long isoform) NF-kappaB2 NF-kappaB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ARHGEF5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARHGEF5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q35 Ensembl cytogenetic band: 7q35 HGNC cytogenetic band: 7q35ARHGEF5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P144052: view genomic region
(about GC identifiers)
Start:
|
144,052,381 bp from pter |
End:
|
144,077,725 bp from pter |
Size:
|
25,345 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 143,390,747-143,415,984 |
|
Proteins
for ARHGEF5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ARHG5_HUMAN, Q12774 (See
protein sequence)Recommended Name: Rho guanine nucleotide exchange factor 5 Size: 1597 amino acids; 176799 Da
Sequence caution: Sequence=BAD18708.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A6NNJ2 Q6ZML7Alternative splicing: 2 isoforms: Q12774-1 Q12774-2 Explore the universe of human proteins at neXtProt for ARHGEF5: NX_Q12774
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q12774
ARHGEF5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_005426.2
ENSEMBL proteins: ENSP00000417979 ENSP00000056217 ENSP00000418745 ENSP00000418227
Human Recombinant Protein Products for ARHGEF5:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
ARHGEF5 for ontologies About GeneDecksing
ARHGEF5 Antibody Products:
Assay Products for ARHGEF5: |
Protein
Domains /
Families
for ARHGEF5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ARHGEF5 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q12774ProtoNet protein and cluster: Q12774 4 Blocks protein families: IPB000219 DH domain IPB001452 SH3 domain signature IPB001849 Pleckstrin-like IPB011511 Variant SH3
UniProtKB/Swiss-Prot: ARHG5_HUMAN, Q12774Similarity: Contains 1 DH (DBL-homology) domainSimilarity: Contains 1 PH domainSimilarity: Contains 1 SH3 domain |
Function
for ARHGEF5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ARHGEF5 for ontologies About GeneDecksing
Phenotypes:
2 GenomeRNAi human phenotypes for ARHGEF5:
4 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Arhgef5):
ARHGEF5 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-outs for ARHGEF5: Arhgef5tm1.2Meg Arhgef5tm1.1Dwu
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGEF5 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGEF5
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ARHGEF5 (NM_005435) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ARHGEF5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARHGEF5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGEF5 |
|
Pathways & Interactions
for ARHGEF5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/15 super-pathways (see all 15) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | GPCR Pathway | | | 2 | G-AlphaQ Signaling | | | 3 | Rho Family GTPases | | | 4 | CCR3 Pathway in Eosinophils | | | 5 | Signaling by Slit | |
5/21 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for ARHGEF5 (see all 21)
1  BioSystems Pathway for ARHGEF5
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ARHGEF5
STRING Interaction
Network Preview (showing 5 interactants - click image to see 12)
5/15 Interacting proteins for ARHGEF5 (Q127742, 3 ENSP000000562174) via UniProtKB, MINT, STRING, and/or I2D (see all 15)About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0002408 | myeloid dendritic cell chemotaxis |
IEA | -- | | GO:0030036 | actin cytoskeleton organization |
IEA | -- | | GO:0032319 | regulation of Rho GTPase activity |
IDA | -- | | GO:0032321 | positive regulation of Rho GTPase activity |
IEA | -- | | GO:0035023 | regulation of Rho protein signal transduction |
-- | -- |
ARHGEF5 for ontologies About GeneDecksing
|
Drugs & Compounds
for ARHGEF5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ARHGEF5
Search CenterWatch for drugs/clinical trials and news about ARHGEF5 / ARHG5
|
Transcripts
for ARHGEF5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ARHGEF5 gene (2 alternative transcripts): NM_005435.3 NM_001002861.1 Unigene Cluster for ARHGEF5: Rho guanine nucleotide exchange factor (GEF) 5 Hs.334 [show with all ESTs]Unigene Representative Sequence: AK1603654 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000498580 ENST00000056217(uc003wek.3 uc003wel.3) ENST00000474817
ENST00000471847(uc003wem.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGEF5 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGEF5
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ARHGEF5 (NM_005435) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ARHGEF5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARHGEF5 |
Additional cDNA sequence: AK090570.1 AK123596.1 AK160365.1 BC010046.2 BC011839.2 BC014555.2 BC136661.1 BX649178.1 CR749203.1 U02082.1 12 DOTS entries: DT.453361 DT.95088786 DT.100751897 DT.102835723 DT.91816105 DT.95373267 DT.91743124 DT.121037323 DT.102769 DT.102845469 DT.111011 DT.91763563 24/176 AceView cDNA sequences (see all 176): BE501425 AA704519 BM712072 AA502595 AI079550 BI020419 BQ953504 CD517373 AI370486 AA595157 C21270 AW663444 AI650944 BG286254 CB216819 BM670360 AI521839 BV178746 BQ935989 BE383988 CD674013 BV199254 BV190709 BV168551
GeneLoc Exon Structure
5/11 Alternative Splicing Database (ASD) splice patterns (SP) for ARHGEF5 (see all 11) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10a | · | 10b | ^ | 11 | ^ | 12a | · | 12b | · | 12c | ^ | 13 | ^ | 14 | ^ | 15a | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | - | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 15b | ^ | 16a | · | 16b | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20a | · | 20b | ^ | 21 | ^ | 22 | ^ | 23 |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ARHGEF5
|
Expression
for ARHGEF5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ARHGEF5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCAAGGGCTG
About this image
See ARHGEF5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ARHGEF5
SOURCE GeneReport for Unigene cluster: Hs.334
UniProtKB/Swiss-Prot: ARHG5_HUMAN, Q12774Tissue specificity: Mainly expressed in kidney, liver, pancreas, lung and placenta
SABiosciences Custom PCR Arrays for ARHGEF5
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ARHGEF5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ARHGEF5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARHGEF5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARHGEF5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGEF5 |
Orthologs
for ARHGEF5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ARHGEF5 gene from 6/19 species (see all 19) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ARHGEF56 |
Uncharacterized protein |
71(a) |
1 ↔ 1 |
1(76788630-76799747) |
lizard
(Anolis carolinensis) |
Reptilia |
ARHGEF56 |
-- |
68(a) |
1 ↔ 1 |
5(82116963-82139906) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.320052 |
Xenopus laevis transcribed sequence with weak similarity to protein refNP_005426.1 (H.sapiens) Rho guanine nucleotide exchange factor 5; oncogene TIM; transforming immortalized mammary oncogene; guanine nucleotide regulatory protein TIM [Homo sapiens] less |
77.85(n) |
|
CA793729.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wu:fd16d016CABZ01012862.16 |
-- |
42(a)21(a) |
possible ortholog1 ↔ 1 |
6(40497429-40503239) 16(19677195-19699399) |
fruit fly
(Drosophila melanogaster) |
Insecta |
BcDNA:GH036933 |
-- |
32(a) |
|
-- |
worm
(Caenorhabditis elegans) |
Secernentea |
K07D4.7a3 |
-- |
34(a)
(best of 2) |
|
II(4004982-4015768) -- |
ENSEMBL Gene Tree for ARHGEF5 (if available)
TreeFam Gene Tree for ARHGEF5 (if available) |
Paralogs
for ARHGEF5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ARHGEF5 gene
- ARHGEF192 ARHGEF152 ARHGEF162 NGEF2 ARHGEF262
7 SIMAP similar genes for ARHGEF5 using alignment to 5 protein entries: ARHG5_HUMAN (see all proteins):ARHGEF35 LOC728377 DKFZp686N1969 SH3GL1 ARHGEF19 ARHGEF16
NGEF
ARHGEF5 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for ARHGEF5
PGOHUM00000233061 PGOHUM00000250918
|
Genomic Variants
for ARHGEF5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ARHGEF5 (144052381 - 144077725 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 14 variations for ARHGEF5
13 CNVs: 64974 2110 0726 32962 59622 4571 70058 3708 94944 70059 82244 4573 31398
1 Inversion: 37284 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ARHGEF5 |
|
Disorders
/ Diseases
for ARHGEF5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ARHGEF5 for disorders About GeneDecksing
OMIM gene information: 600888
OMIM disorders: --
5  diseases for ARHGEF5: About MalaCardshepatocellular carcinoma carcinoma breast cancer adenocarcinoma
pancreatitis
Human Genome Epidemiology (HuGE) Navigator: ARHGEF5 (3 documents)
Export disorders for ARHGEF5 gene to outside databases
|
Publications
for ARHGEF5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ARHGEF5 gene, integrated from 9 sources (see all 27):
(articles sorted by number of sources associating them with ARHGEF5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Expression cDNA cloning of a novel oncogene with sequence similarity to regulators of small GTP-binding proteins. (PubMed id 8134109)1, 2, 3, 9 Chan A.M.-L.... Miki T. (1994)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
- Assignment of the human TIM proto-oncogene to 7q33-->q35. (PubMed id 7656213)1, 3 Takai S....Miki T. (1995)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- The guanine nucleotide exchange factor Arhgef5 plays crucial roles in Src-induced podosome formation. (PubMed id 21525037)1 Kuroiwa M....Okada M. (2011)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
|
External Searches for ARHGEF5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ARHGEF5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ARHGEF5 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ARHGEF5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for ARHGEF5 gene:
Search GeneIP for patents involving ARHGEF5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ARHGEF5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
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| | |  | OriGene Antibodies for ARHGEF5 | | OriGene shRNA RFP for ARHGEF5 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ARHGEF5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ARHGEF5 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ARHGEF5 | | OriGene 3'-UTR Clone for ARHGEF5 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGEF5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGEF5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ARHGEF5 | | OriGene Custom Protein Services for ARHGEF5 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ARHGEF5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ARHGEF5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARHGEF5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ARHGEF5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARHGEF5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARHGEF5 |
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| | | | Search Tocris compounds for ARHGEF5 |
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 | | | ARHGEF5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGEF5 |
|  |  |  |  | | | | ThermoFisher Antibodies for ARHGEF5 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARHGEF5 |
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