Aliases for ARHGEF5 Gene
External Ids for ARHGEF5 Gene
Previous GeneCards Identifiers for ARHGEF5 Gene
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. [provided by RefSeq, Jul 2008]
GeneCards Summary for ARHGEF5 Gene
ARHGEF5 (Rho Guanine Nucleotide Exchange Factor (GEF) 5) is a Protein Coding gene. Among its related pathways are RhoGDI Pathway and Apoptotic Pathways in Synovial Fibroblasts. GO annotations related to this gene include GTP binding and Rho guanyl-nucleotide exchange factor activity. An important paralog of this gene is ARHGEF19.