Aliases for ARHGEF40 Gene
External Ids for ARHGEF40 Gene
Previous GeneCards Identifiers for ARHGEF40 Gene
This gene encodes a protein similar to guanosine nucleotide exchange factors for Rho GTPases. The encoded protein contains in its C-terminus a GEF domain involved in exchange activity and a pleckstrin homology domain. Alternatively spliced transcripts that encode different proteins have been described. [provided by RefSeq, Mar 2014]
GeneCards Summary for ARHGEF40 Gene
ARHGEF40 (Rho Guanine Nucleotide Exchange Factor 40) is a Protein Coding gene. Among its related pathways are p75 NTR receptor-mediated signalling and Signaling by GPCR. GO annotations related to this gene include Rho guanyl-nucleotide exchange factor activity. An important paralog of this gene is PLEKHG4.
UniProtKB/Swiss-Prot for ARHGEF40 Gene
May act as a guanine nucleotide exchange factor (GEF).