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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ARHGEF26 Gene

protein-coding   GIFtS: 49
GCID: GC03P153839

Rho Guanine Nucleotide Exchange Factor (GEF) 26

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Rho Guanine Nucleotide Exchange Factor (GEF) 261 2     CSGEF2
Src Homology 3 Domain-Containing Guanine Nucleotide Exchange Factor1 2     HMFN18642
SGEF2 3     Rho Guanine Nucleotide Exchange Factor 262
SH3 Domain-Containing Guanine Exchange Factor2 3     

External Ids:    HGNC: 244901   Entrez Gene: 260842   Ensembl: ENSG000001147907   UniProtKB: Q96DR73   

Export aliases for ARHGEF26 gene to outside databases

Previous GC identifer: GC03P151230


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ARHGEF26 Gene:
This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate
Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays
a role in the promotion of macropinocytosis. Underexpression of the encoded protein may be a predictive marker of
chemoresistant disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed
for this gene. (provided by RefSeq, Oct 2011)

GeneCards Summary for ARHGEF26 Gene: 
ARHGEF26 (Rho guanine nucleotide exchange factor (GEF) 26) is a protein-coding gene. Diseases associated with ARHGEF26 include typhoid fever, and hepatoblastoma. GO annotations related to this gene include phospholipid binding and Rho guanyl-nucleotide exchange factor activity. An important paralog of this gene is ARHGEF19.

UniProtKB/Swiss-Prot: ARHGQ_HUMAN, Q96DR7
Function: Activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane
ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial
migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton
rearrangements and promotes bacterial entry




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NT_005612.16  NC_018914.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for ARHGEF26
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidARHGEF26 promoter sequence
   Search SABiosciences Chromatin IP Primers for ARHGEF26

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARHGEF26


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q25.2   Ensembl cytogenetic band:  3q25.2   HGNC cytogenetic band: 3q25.2

ARHGEF26 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARHGEF26 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P153839:  view genomic region     (about GC identifiers)

Start:
153,838,792 bp from pter      End:
153,975,616 bp from pter
Size:
136,825 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ARHGQ_HUMAN, Q96DR7 (See protein sequence)
Recommended Name: Rho guanine nucleotide exchange factor 26  
Size: 871 amino acids; 97346 Da
Subunit: Interacts with ICAM1 and RHOG
Subcellular location: Cell projection, ruffle
Sequence caution: Sequence=AAH16628.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAL27002.1; Type=Miscellaneous discrepancy; Note=Intron retention; Sequence=BAB14159.1; Type=Erroneous
initiation; Note=Translation N-terminally extended; Sequence=BAB14292.1; Type=Erroneous initiation;
Note=Translation N-terminally extended;
Secondary accessions: B3KVP8 E9PBD0 Q68CL1 Q6AZ96 Q6Q8Q8 Q96AW8 Q96DR6 Q9H9D7 Q9H9R2 Q9UFW5
Alternative splicing: 3 isoforms:  Q96DR7-1   Q96DR7-3   Q96DR7-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ARHGEF26: NX_Q96DR7

Explore proteomics data for ARHGEF26 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96DR7

  • ARHGEF26 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ARHGEF26 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001238891.1  NP_001238892.1  NP_056410.3  

    ENSEMBL proteins: 
     ENSP00000348828   ENSP00000423418   ENSP00000424446   ENSP00000423295  

    Human Recombinant Protein Products for ARHGEF26: 
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    Cloud-Clone Corp. Proteins for ARHGEF26 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001726ruffle IEA--
    GO:0005622intracellular ----

    ARHGEF26 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    PLEKH: Pleckstrin homology (PH) domain containing
    ARHGEF: Rho guanine nucleotide exchange factors

    4 InterPro protein domains:
     IPR000219 DH-domain
     IPR001849 Pleckstrin_homology
     IPR001452 SH3_domain
     IPR011993 PH_like_dom

    Graphical View of Domain Structure for InterPro Entry Q96DR7

    ProtoNet protein and cluster: Q96DR7

    3 Blocks protein domains:
    IPB000219 DH domain
    IPB001452 SH3 domain signature
    IPB001849 Pleckstrin-like


    UniProtKB/Swiss-Prot: ARHGQ_HUMAN, Q96DR7
    Similarity: Contains 1 DH (DBL-homology) domain
    Similarity: Contains 1 PH domain
    Similarity: Contains 1 SH3 domain


    ARHGEF26 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ARHGQ_HUMAN, Q96DR7
    Function: Activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane
    ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial
    migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton
    rearrangements and promotes bacterial entry
    Induction: Certain mRNA species appear to be up-regulated by androgens in prostate cancer cells

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005089Rho guanyl-nucleotide exchange factor activity IEA--
    GO:0005515protein binding ----
    GO:0005543phospholipid binding IEA--
         
    ARHGEF26 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ARHGEF26:
     Increased gamma-H2AX phosphory 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Arhgef26):
     cardiovascular system 

    ARHGEF26 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Arhgef26tm1.1Kbur for ARHGEF26

       inGenious Targeting Laboratory - Custom generated mouse model solutions for ARHGEF26 
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    SwitchGear 3'UTR luciferase reporter plasmidARHGEF26 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ARHGEF26 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Bacterial invasion of epithelial cells
    Bacterial invasion of epithelial cells

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for ARHGEF26):
        Bacterial invasion of epithelial cells


    ARHGEF26 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ARHGEF26

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for ARHGEF26 (ENSP000003488284) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RHOGENSP000003394674STRING: ENSP00000339467
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0035023regulation of Rho protein signal transduction IEA--

    ARHGEF26 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ARHGEF26 (ARHGQ)

    Search CenterWatch for drugs/clinical trials and news about ARHGEF26 / ARHGQ

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ARHGEF26 gene (3 alternative transcripts): 
    NM_001251962.1  NM_001251963.1  NM_015595.3  

    Unigene Cluster for ARHGEF26:

    Rho guanine nucleotide exchange factor (GEF) 26
    Hs.240845  [show with all ESTs]
    Unigene Representative Sequence: NM_001251962
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000356448(uc021xgc.1 uc011bog.1 uc011boh.1) ENST00000465093
    ENST00000496710 ENST00000465817 ENST00000483068(uc011boi.1)
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    SwitchGear 3'UTR luciferase reporter plasmidARHGEF26 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARHGEF26
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    Additional mRNA sequence: 

    AB073386.1 AF415175.1 AF415176.1 AK022655.1 AK022884.1 AK123040.1 AK127282.1 AL117429.1 
    AY552599.1 BC016628.1 BC078655.1 

    8 DOTS entries:

    DT.407924  DT.100748311  DT.95322803  DT.101981041  DT.97800976  DT.120912783  DT.97780247  DT.102824403 

    24/113 AceView cDNA sequences (see all 113):

    BX503267 AU125271 CB122093 BM729068 W96189 AA425141 AA364836 BM987736 
    BM793807 AW663096 BQ446856 AA860087 AK127282 AI017789 BU754524 AI050702 
    AU150420 BE879255 AB073386 AI740900 AI042352 CB047698 BE708807 NM_015595 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ARHGEF26 expression in normal human tissues (normalized intensities)      ARHGEF26 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CATCTTATGA
    ARHGEF26 Expression
    About this image


    ARHGEF26 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Blood (Hematopoietic System)
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
     
     Prostate (Endocrine System)

    See ARHGEF26 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ARHGEF26

    SOURCE GeneReport for Unigene cluster: Hs.240845

    UniProtKB/Swiss-Prot: ARHGQ_HUMAN, Q96DR7
    Tissue specificity: Isoform 1 is broadly expressed, with highest levels in liver (at protein level). Certain mRNA
    species appear to be specifically expressed in prostate and liver

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ARHGEF26 gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Arhgef261 , 5 Rho guanine nucleotide exchange factor (GEF) 261, 5 84.64(n)1
    87.18(a)1
      3 (29.97 cM)5
    6224341  NM_001081295.11  NP_001074764.11 
     623383445 
    chicken
    (Gallus gallus)
    Aves ARHGEF261 Rho guanine nucleotide exchange factor (GEF) 26 76.38(n)
    82.71(a)
      429163  XM_426718.3  XP_426718.3 
    lizard
    (Anolis carolinensis)
    Reptilia ARHGEF266
    Uncharacterized protein
    72(a)
    1 ↔ 1
    3(16704689-16787484)
    fruit fly
    (Drosophila melanogaster)
    Insecta Exn6
    Ephexin
    9(a)
    1 → many
    3L(16963113-16987488)
    worm
    (Caenorhabditis elegans)
    Secernentea tag-2186
    Protein TAG-218, isoform a
    20(a)
    1 → many
    II(4004889-4016077)


    ENSEMBL Gene Tree for ARHGEF26 (if available)
    TreeFam Gene Tree for ARHGEF26 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ARHGEF26 gene
    ARHGEF192  ARHGEF152  ARHGEF162  NGEF2  ARHGEF52  
    3 SIMAP similar genes for ARHGEF26 using alignment to 1 protein entry:     ARHGQ_HUMAN:
    ARHGEF16    LOC728377    NGEF

    ARHGEF26 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2859 SNPs in ARHGEF26 are shown (see all 2859)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0582054
    ----see VAR_0582052 L P mis40--------
    rs1113813721,2
    C--151255847(+) GTGTCTAA/-TAATT 3 -- cds11Minor allele frequency- -:0.50CSA 2
    rs105414561,2
    C--151258671(+) TAATA-/AATT  
            
    AATAT
    3 -- int11Minor allele frequency- AATT:0.00CSA 2
    rs114155971,2
    C--151259558(+) TTTTTT/-GGTTG 3 -- int1 trp32Minor allele frequency- -:0.00NA CSA 4
    rs40666241,2
    C--151265167(+) ATAAC-/AAAAG 
            
    TATAA
    3 -- int11Minor allele frequency- AAAAG:0.50NA 2
    rs105222831,2
    C--151266585(+) CTTTT-/AAAACA
            
    TTTCT
    3 -- int10--------
    rs677056191,2
    C--151288954(+) TCTCT-/AT/TA 
            
    GAGAA
    3 -- int10--------
    rs105760981,2
    C--151298969(+) CATAT-/ATAATGAT 3 -- int10--------
    rs1495145921,2
    C--151306424(+) TTGGG-/TGTTTT 3 -- int10--------
    rs601583331,2
    C--151325779(+) GAGAG-/AG    
       
    /AGTG
    TGTGT
    3 -- int10--------

    HapMap Linkage Disequilibrium report for ARHGEF26 (153838792 - 153975616 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for ARHGEF26:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv1003556CNV Insertion20482838
    nsv508962CNV Insertion20534489
    nsv4072CNV Insertion18451855
    esv1286199CNV Insertion17803354

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    5 diseases for ARHGEF26:    About MalaCards
    typhoid fever    hepatoblastoma    endotheliitis    prostate cancer
    prostatitis


    ARHGEF26 for disorders           About GeneDecksing


    Export disorders for ARHGEF26 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ARHGEF26 gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with ARHGEF26)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation of the novel human guanine nucleotide exchange factor Src homology 3 domain-containing guanine nucleotide exchange factor (SGEF) and of C-terminal SGEF, an N-terminally truncated form of SGEF, the expression of which is regulated by androgen in prostate cancer cells. (PubMed id 12697679)1, 2, 3, 9 Qi H.... Labrie C. (2003)
    2. SGEF, a RhoG guanine nucleotide exchange factor that stimulates macropinocytosis. (PubMed id 15133129)1, 2, 3 Ellerbroek S.M.... Burridge K. (2004)
    3. Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas. (PubMed id 15221005)1, 2 Yamada S....Nakagawara A. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Differential activation and function of Rho GTPases during Salmonella-host cell interactions. (PubMed id 17074883)2, 9 Patel J.C. and Galan J.E. (2006)
    6. The invasive capacity of HPV transformed cells require s the hDlg-dependent enhancement of SGEF/RhoG activity. (PubMed id 22383878)1 Krishna Subbaiah V....Banks L. (2012)
    7. SGEF is overexpressed in prostate cancer and contribut es to prostate cancer progression. (PubMed id 22824926)1 Wang H....Zhou J. (2012)
    8. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    9. Comparative proteomic analysis of advanced serous epi thelial ovarian carcinoma: possible predictors of chemoresistant disease. (PubMed id 21332407)1 Kim S.W....Kim Y.T. (2011)
    10. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26084 HGNC: 24490 AceView: SGEF Ensembl:ENSG00000114790 euGenes: HUgn26084
    ECgene: ARHGEF26 Kegg: 26084 H-InvDB: ARHGEF26

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ARHGEF26 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ARHGEF26 gene:
    Search GeneIP for patents involving ARHGEF26

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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