ARHGEF25 Gene
protein-coding GIFtS: 49
GCID: GC12P058004
|
|
Rho guanine nucleotide exchange factor (GEF) 25
| |
Aliases
for ARHGEF25 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Rho Guanine Nucleotide Exchange Factor (GEF) 251 2 | | RhoA/Rac/Cdc42 Guanine Nucleotide Exchange Factor GEFT2 3 | | GEFT1 2 3 | | RAC/CDC42 Exchange Factor2 | | P63RhoGEF1 | | Rho Guanine Nucleotide Exchange Factor 252 | | Guanine Nucleotide Exchange Factor GEFT2 3 | | RhoA/RAC/CDC42 Exchange Factor2 | | Rac/Cdc42/Rho Exchange Factor GEFT2 3 | | |
Export aliases for ARHGEF25 gene to outside databasesPrevious GC identifer: GC12P055041 |
Summaries
for ARHGEF25 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ARHGEF25:
Rho GTPases alternate between an inactive GDP-bound state and an active GTP-bound state, and GEFs facilitate GDP/GTPexchange. This gene encodes a guanine nucleotide exchange factor (GEF) which interacts with Rho GTPases involved incontraction of vascular smooth muscles, regulation of responses to angiotensin II and lens cell differentiation.Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Jan 2012)
UniProtKB/Swiss-Prot: ARHGP_HUMAN, Q86VW2Function: May play a role in actin cytoskeleton reorganization in different tissues since its activation inducesformation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases.Links specifically G alpha q/11-coupled receptors to RHOA activation. May be an important regulator of processesinvolved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. Involved inskeletal myogenesis (By similarity)
Gene Wiki entry for ARHGEF25 (GEFT)
|
Genomic Views
for ARHGEF25 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_029419.12
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for ARHGEF25
Other transcription factors
Search SABiosciences Chromatin IP Primers for ARHGEF25
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARHGEF25 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q13.3 Ensembl cytogenetic band: 12q13.3 HGNC cytogenetic band: 12q13.3ARHGEF25 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12P058004: view genomic region
(about GC identifiers)
Start:
|
58,003,963 bp from pter |
End:
|
58,013,162 bp from pter |
Size:
|
9,200 bases |
Orientation:
|
plus strand |
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Proteins
for ARHGEF25 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ARHGP_HUMAN, Q86VW2 (See
protein sequence)Recommended Name: Rho guanine nucleotide exchange factor 25 Size: 580 amino acids; 63843 Da
Subunit: Interacts (via the DH domain) with BVES (via the C-terminus cytoplasmic tail) (By similarity). Interacts withactivated GNAQ and GNA11. Interacts with RHOA, CDC42 and RAC1
Subcellular location: Cell membrane (By similarity). Cytoplasm, myofibril, sarcomere. Note=Highly colocalizes withactin regions
1 PDB 3D structure from  and Proteopedia  for ARHGEF25:2RGN (3D)
Secondary accessions: A6NJH5 Q8WV84 Q96E63Alternative splicing: 2 isoforms: Q86VW2-1 Q86VW2-2 Explore the universe of human proteins at neXtProt for ARHGEF25: NX_Q86VW2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q86VW2
ARHGEF25 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001104740.1 NP_891992.2
ENSEMBL proteins: ENSP00000335560 ENSP00000286494 Reactome Protein details: Q86VW2
Human Recombinant Protein Products for ARHGEF25:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
ARHGEF25 for ontologies About GeneDecksing
ARHGEF25 Antibody Products:
Assay Products for ARHGEF25: |
Protein
Domains /
Families
for ARHGEF25 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ARHGEF25 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q86VW2ProtoNet protein and cluster: Q86VW2 2 Blocks protein families: IPB000219 DH domain IPB001849 Pleckstrin-like
UniProtKB/Swiss-Prot: ARHGP_HUMAN, Q86VW2Domain: The guanine nucleotide exchange activity is autoinhibited by the PH domainSimilarity: Contains 1 DH (DBL-homology) domainSimilarity: Contains 1 PH domain |
Function
for ARHGEF25 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ARHGP_HUMAN, Q86VW2Function: May play a role in actin cytoskeleton reorganization in different tissues since its activation inducesformation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases.Links specifically G alpha q/11-coupled receptors to RHOA activation. May be an important regulator of processesinvolved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. Involved inskeletal myogenesis (By similarity) Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005089 | Rho guanyl-nucleotide exchange factor activity |
IEA | -- | | GO:0005543 | phospholipid binding |
IEA | -- |
ARHGEF25 for ontologies About GeneDecksing
Phenotypes:
2 GenomeRNAi human phenotypes for ARHGEF25:
3 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Arhgef25):
ARHGEF25 for phenotypes About GeneDecksing
Animal Models:
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGEF25 (see all 4)
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGEF25 |
|
Pathways & Interactions
for ARHGEF25 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Signaling by GPCR | | | 2 | G alpha (q) signalling events | | | 3 | Regulation of RAC1 activity | | | 4 | Regulation of RhoA activity | | | 5 | Regulation of CDC42 activity | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3  BioSystems Pathways for ARHGEF25
5 
Reactome Pathways for ARHGEF25
ARHGEF25 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ARHGEF25
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/121 Interacting proteins for ARHGEF25 (Q86VW23 ENSP000003355604) via UniProtKB, MINT, STRING, and/or I2D (see all 121)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0035023 | regulation of Rho protein signal transduction |
IEA | -- |
ARHGEF25 for ontologies About GeneDecksing
|
Drugs & Compounds
for ARHGEF25 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ARHGEF25
Search CenterWatch for drugs/clinical trials and news about ARHGEF25 / ARHGP
|
Transcripts
for ARHGEF25 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ARHGEF25 gene (3 alternative transcripts): NM_133483.2 NM_001111270.2 NM_182947.3 Unigene Cluster for ARHGEF25: Rho guanine nucleotide exchange factor (GEF) 25 Hs.61581 [show with all ESTs]Unigene Representative Sequence: NR_0462237 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000333972(uc009zpy.3 uc001soz.1) ENST00000286494(uc001spb.3 uc001spa.3)
ENST00000471370 ENST00000469072 ENST00000466399 ENST00000484357 ENST00000477314
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGEF25 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGEF25 (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ARHGEF25 (NM_182947) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ARHGEF25 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARHGEF25 |
Additional cDNA sequence: AB370196.1 AF487514.2 BC012860.1 BC018536.1 BC047559.1 NR_046223.1 6 DOTS entries: DT.454962 DT.100748921 DT.121109105 DT.95160261 DT.100733656 DT.121109103 24/122 AceView cDNA sequences (see all 122): BM783095 CR599416 BX451871 BM748075 BM740405 BX112080 AA463846 AI018809 BM750262 BM783700 AW161485 AI654427 AW264299 AA325176 AI677902 AK057416 BM759898 BM783729 BM783082 CD722079 CR624415 AL536956 AA031486 AI089627
GeneLoc Exon Structure
|
Expression
for ARHGEF25 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ARHGEF25 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTCCCCCCAA
About this image
See ARHGEF25 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ARHGEF25
SOURCE GeneReport for Unigene cluster: Hs.61581
UniProtKB/Swiss-Prot: ARHGP_HUMAN, Q86VW2Tissue specificity: Isoform 1 and isoform 2 are highly expressed in excitable tissues, such as brain, heart and muscle.Also detected in kidney and liver
SABiosciences Custom PCR Arrays for ARHGEF25
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ARHGEF25
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGEF25 |
Orthologs
for ARHGEF25 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ARHGEF25 gene from 4/16 species (see all 16) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
--ARHGEF256 |
-- |
7(a)50(a) |
possible ortholog1 ↔ 1 |
1(78246630-78466631) AAWZ02040341(1348-5714) |
zebrafish
(Danio rerio) |
Actinopterygii |
arhgef25b1 |
Rho guanine nucleotide exchange factor (GEF) 25b |
59.25(n)
58.94(a) |
|
569561 XM_692957.4 XP_698049.4 |
fruit fly
(Drosophila melanogaster) |
Insecta |
trio6 |
trio |
6(a) |
possible ortholog |
3L(995982-1034875) |
worm
(Caenorhabditis elegans) |
Secernentea |
unc-736 |
UNCoordinated family member (unc-73) |
3(a) |
possible ortholog |
I(3999345-4031629) |
ENSEMBL Gene Tree for ARHGEF25 (if available)
TreeFam Gene Tree for ARHGEF25 (if available) |
Paralogs
for ARHGEF25 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ARHGEF25 gene
- KALRN2 PLEKHG4B2 MCF2L22 TRIO2 MCF2L2 KIAA17552 PLEKHG42 MCF22
- ARHGEF402
4 SIMAP similar genes for ARHGEF25 using alignment to 2 protein entries: ARHGP_HUMAN (see all proteins):GEFT tgat KALRN TRIO
ARHGEF25 for paralogs About GeneDecksing
|
Genomic Variants
for ARHGEF25 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ARHGEF25 (58003963 - 58013162 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ARHGEF25: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ARHGEF25 |
|
Disorders
/ Diseases
for ARHGEF25 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ARHGEF25 for disorders About GeneDecksing
OMIM gene information: 610215
OMIM disorders: --
2  diseases for ARHGEF25: About MalaCardsgout neuronitis
Export disorders for ARHGEF25 gene to outside databases
|
Publications
for ARHGEF25 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ARHGEF25 gene, integrated from 9 sources (see all 19):
(articles sorted by number of sources associating them with ARHGEF25) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A Rac/Cdc42-specific exchange factor, GEFT, induces cell proliferation, transformation, and migration. (PubMed id 12547822)1, 2, 3, 9 Guo X.... Liu M. (2003)
- p63RhoGEF and GEFT are Rho-specific guanine nucleotide exchange factors encoded by the same gene. (PubMed id 15069594)1, 2, 9 Lutz S....Wieland T. (2004)
- Structure of Galphaq-p63RhoGEF-RhoA complex reveals a pathway for the activation of RhoA by GPCRs. (PubMed id 18096806)1, 2 Lutz S....Tesmer J.J. (2007)
- The guanine nucleotide exchange factor p63RhoGEF, a specific link between Gq/11-coupled receptor signaling and RhoA. (PubMed id 15632174)1, 2 Lutz S.... Wieland T. (2005)
- Modulation of muscle regeneration, myogenesis, and adipogenesis by the Rho family guanine nucleotide exchange factor GEFT. (PubMed id 16314529)1, 2 Bryan B.A....Liu M. (2005)
- Human p63RhoGEF, a novel RhoA-specific guanine nucleotide exchange factor, is localized in cardiac sarcomere. (PubMed id 11861769)1, 2 Souchet M.... Calmels T.P. (2002)
- p63RhoGEF couples GI+(q/11)-mediated signaling to Ca2+ sensitization of vascular smooth muscle contractility. (PubMed id 21885830)1 Momotani K....Somlyo A.V. (2011)
- Plasma membrane association of p63 Rho guanine nucleo tide exchange factor (p63RhoGEF) is mediated by palmitoylation and is required for basal activity in cells. (PubMed id 21832057)1 Aittaleb M....Tesmer J.J. (2011)
- GEFT, A Rho family guanine nucleotide exchange factor , regulates lens differentiation through a Rac1-mediated mechanism. (PubMed id 21663592)1 Mitchell D.C....Li D.W. (2011)
- Does p63RhoGEF, a new key mediator of angiotensin II signalling, play a role in blood pressure regulation and cardiovascular remodel ling in humans? (PubMed id 22147804)1 CalA^ L.A....Pessina A.C. (2011)
|
External Searches for ARHGEF25 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ARHGEF25 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ARHGEF25 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ARHGEF25 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for ARHGEF25 gene:
Search GeneIP for patents involving ARHGEF25
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ARHGEF25 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
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