Aliases for ARHGEF16 Gene
External Ids for ARHGEF16 Gene
Although the specific function of this protein is not known yet, it is thought to be involved in protein-protein and protein-lipid interactions. [provided by RefSeq, Jul 2008]
GeneCards Summary for ARHGEF16 Gene
ARHGEF16 (Rho Guanine Nucleotide Exchange Factor (GEF) 16) is a Protein Coding gene. Diseases associated with ARHGEF16 include neuroblastoma. Among its related pathways are Signaling by FGFR and RhoGDI Pathway. GO annotations related to this gene include phospholipid binding and Rho guanyl-nucleotide exchange factor activity. An important paralog of this gene is ARHGEF19.
UniProtKB/Swiss-Prot for ARHGEF16 Gene
Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP. May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2. May also activate CDC42 and mediate activation of CDC42 by the viral protein HPV16 E6.