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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ARHGEF10L Gene

protein-coding   GIFtS: 56
GCID: GC01P017866

Rho guanine nucleotide exchange factor (GEF) 10-like

 Explore 4 diseases affiliated with
ARHGEF10L via our new
 Human Malady Compendium 
Biological research products
for ARHGEF10L
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Rho Guanine Nucleotide Exchange Factor (GEF) 10-Like1 2
KIAA16261 3 5
GrinchGEF2 3
GRINCHGEF3 5
FLJ105211
Rho Guanine Nucleotide Exchange Factor 10-Like Protein2

External Ids:    HGNC: 255401   Entrez Gene: 551602   Ensembl: ENSG000000749647   OMIM: 6124945   UniProtKB: Q9HCE63   

Export aliases for ARHGEF10L gene to outside databases

Previous GC identifers: GC01P017612 GC01P017738 GC01P016112


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ARHGEF10L:
ARHGEF10L is a member of the RhoGEF family of guanine nucleotide exchange factors (GEFs) that activate Rho GTPases
(Winkler et al., 2005 (PubMed 16112081)).(supplied by OMIM, Dec 2008)

UniProtKB/Swiss-Prot: ARGAL_HUMAN, Q9HCE6
Function: Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004610.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ARHGEF10L gene promoter:
         c-Fos   AP-1   RelA   Tal-1beta   HNF-1A   E47   GATA-1   HNF-1   SEF-1 (1)   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): ARHGEF10L promoter sequence
   Search SABiosciences Chromatin IP Primers for ARHGEF10L

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARHGEF10L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.13   Ensembl cytogenetic band:  1p36.13   HGNC cytogenetic band: 1p36.13

ARHGEF10L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARHGEF10L gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P017866:  view genomic region     (about GC identifiers)

Start:
17,866,330 bp from pter      End:
18,024,370 bp from pter
Size:
158,041 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ARGAL_HUMAN, Q9HCE6 (See protein sequence)
Recommended Name: Rho guanine nucleotide exchange factor 10-like protein  
Size: 1279 amino acids; 140409 Da
Subunit: Interacts with RHOA, RHOB and RHOC
Subcellular location: Cytoplasm
Sequence caution: Sequence=BAA91663.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=BAB13452.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=BAC03792.1;
Type=Erroneous termination; Positions=931; Note=Translated as Arg;
Secondary accessions: B7ZKS1 Q17RW1 Q3YFJ4 Q5VXI5 Q5VXI6 Q66K51 Q6P0L7 Q8NAV5 Q9NVT3
Alternative splicing: 5 isoforms:  Q9HCE6-1   Q9HCE6-2   Q9HCE6-3   Q9HCE6-4   Q9HCE6-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ARHGEF10L: NX_Q9HCE6

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9HCE6

  • ARHGEF10L Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001011722.2  NP_060595.3  

    ENSEMBL proteins: 
     ENSP00000355060   ENSP00000364564   ENSP00000364557   ENSP00000399401   ENSP00000394621  
     ENSP00000364569   ENSP00000167825  

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    Uscn Proteins for ARHGEF10L

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005737cytoplasm IEA--
    GO:0005829cytosol ----


    ARHGEF10L for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ARHGEF10L for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR000219 DH-domain
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q9HCE6

    ProtoNet protein and cluster: Q9HCE6

    1 Blocks protein family: IPB000219 DH domain

    UniProtKB/Swiss-Prot: ARGAL_HUMAN, Q9HCE6
    Similarity: Contains 1 DH (DBL-homology) domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: ARGAL_HUMAN, Q9HCE6
    Function: Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC

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    Inhib. RNA
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005089Rho guanyl-nucleotide exchange factor activity IEA--
    GO:0005100Rho GTPase activator activity ----


    ARHGEF10L for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1G-protein signaling_RhoA regulation pathway
    G-protein signaling RhoB regulation pathway0.16
    G-protein signaling_RhoB regulation pathway0.16
    2Regulation of RhoA activity
    Regulation of RhoA activity1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for ARHGEF10L
        G-protein signaling RhoB regulation pathway


    1 GeneGo (Thomson Reuters) Pathway for ARHGEF10L
        G-protein signaling RhoB regulation pathway

    1 BioSystems Pathway for ARHGEF10L 
        Regulation of RhoA activity



    ARHGEF10L for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ARHGEF10L

    STRING Interaction Network Preview (showing 5 interactants - click image to see 23)

    5/30 Interacting proteins for ARHGEF10L (Q9HCE62, 3 ENSP000003550604) via UniProtKB, MINT, STRING, and/or I2D (see all 30)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ANXA9O760272, 3, ENSP000003579434MINT-64952 I2D: score=4 STRING: ENSP00000357943
    DRAP1Q149192, 3MINT-64953 I2D: score=4 
    SCN2AQ992502, 3MINT-64955 I2D: score=3 
    NR4A1P227363, ENSP000002430504I2D: score=3 STRING: ENSP00000243050
    SCN1AP354983I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0032321positive regulation of Rho GTPase activity ----
    GO:0035023regulation of Rho protein signal transduction IEA--
    GO:0051496positive regulation of stress fiber assembly ----


    ARHGEF10L for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ARHGEF10L

    3 HMDB Compounds for ARHGEF10L    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine diphosphate5'-GDP (see all 10)146-91-8--
    Guanosine monophosphate5'-GMP (see all 14)85-32-5--
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--
    Search CenterWatch for drugs/clinical trials and news about ARHGEF10L / ARGAL 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ARHGEF10L gene (2 alternative transcripts): 
    NM_001011722.2  NM_018125.3  

    Unigene Cluster for ARHGEF10L:

    Rho guanine nucleotide exchange factor (GEF) 10-like
    Hs.443460  [show with all ESTs]
    Unigene Representative Sequence: BC111058
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000361221(uc001ban.3) ENST00000375415 ENST00000482892 ENST00000469726(uc001baq.3)
    ENST00000375408(uc010ocs.2 uc001bar.3) ENST00000475356(uc009vpf.3)
    ENST00000482359 ENST00000466782 ENST00000495593(uc001bas.3) ENST00000452522(uc009vpe.1 uc001bao.3 uc001bap.3)
    ENST00000434513 ENST00000375420(uc010ocr.1) ENST00000167825

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    hsa-miR-34b* hsa-miR-362-3p hsa-let-7a-2* hsa-miR-342-3p hsa-miR-329 hsa-let-7g* hsa-miR-129-5p hsa-miR-377
    SwitchGear 3'UTR luciferase reporter plasmidARHGEF10L 3' UTR sequence
    Inhib. RNA
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    Additional cDNA sequence: 

    AB046846.1 AK001383.1 AK092020.1 AK126877.1 AK300174.1 AK300264.1 AK311076.1 BC003073.2 
    BC065561.1 BC080596.1 BC111058.1 BC115368.1 BC117171.1 BC143347.1 DQ139833.1 

    14 DOTS entries:

    DT.100758544  DT.101973046  DT.205454  DT.100758546  DT.121409662  DT.40295251  DT.95149222  DT.121409680 
    DT.100758545  DT.40294200  DT.91949327  DT.95192915  DT.91699872  DT.95136595 

    24/134 AceView cDNA sequences (see all 134):

    BQ945883 BF447312 CO246708 AI697019 CA394245 AI698350 CB528729 Z44984 
    BC029928 CB068401 CD675442 F03939 AI950680 BU154066 CD679096 CA487411 
    BU608323 BE563281 CK818931 AI913628 AU127232 BM975509 CO248384 BM745839 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for ARHGEF10L (see all 12)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15a · 15b ^ 16a · 16b ^ 17 ^ 18 ^ 19a · 19b ^
    SP1:        -                                                     -           -                                                                 -               
    SP2:                                                        -     -           -                                                                 -               
    SP3:                                                                          -                                                                 -               
    SP4:                                                                                                  -     -     -     -                       -               
    SP5:                                                                                                                                            -               

    ExUns: 20 ^ 21 ^ 22 ^ 23 ^ 24a · 24b ^ 25 ^ 26a · 26b ^ 27a · 27b ^ 28 ^ 29 ^ 30 ^ 31 ^ 32a · 32b ^ 33
    SP1:              -     -     -                                                           -     -               
    SP2:              -     -     -                                                           -     -               
    SP3:              -     -     -                                                           -     -               
    SP4:              -     -     -                                                           -     -               
    SP5:              -     -     -                                                                 -               


    ECgene alternative splicing isoforms for ARHGEF10L

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ARHGEF10L expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CGGGAGCCGG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See ARHGEF10L Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ARHGEF10L

    SOURCE GeneReport for Unigene cluster: Hs.443460

    UniProtKB/Swiss-Prot: ARGAL_HUMAN, Q9HCE6
    Tissue specificity: Detected in heart, liver, skeletal muscle, kidney and pancreas

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ARHGEF10L gene from 5/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves ARHGEF10L1 Rho guanine nucleotide exchange factor (GEF) 10-like 76.4(n)
    79.24(a)
      419360  XM_003642508.1  XP_003642556.1 
    lizard
    (Anolis carolinensis)
    Reptilia ARHGEF10L6
    --
    91(a)
    1 ↔ 1
    AAWZ02040076(914-6841)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.126152 Xenopus laevis transcribed sequence with weak similarity more 77.36(n)    BJ071182.1 
    zebrafish
    (Danio rerio)
    Actinopterygii arhgef10lb6
    BX548000.26
    --
    53(a)
    52(a)
    1 ↔ many
    1 ↔ many
    23(21835130-21928792)
    11(30211398-30428820)
    fruit fly
    (Drosophila melanogaster)
    Insecta CG436586
    --
    13(a)
    1 → many
    X(17350590-17455214)


    ENSEMBL Gene Tree for ARHGEF10L (if available)
    TreeFam Gene Tree for ARHGEF10L (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ARHGEF10L gene
    ECT22  ARHGEF102  SPAG92  ARHGEF172  MAPK8IP32  
    1 SIMAP similar gene for ARHGEF10L using alignment to 3 protein entries:     ARGAL_HUMAN (see all proteins):
    ARHGEF10

    ARHGEF10L for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2953 NCBI SNPs in ARHGEF10L are shown (see all 2953    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs22451481,2
    C,F,A,H,--17864514(-) AGCTCG/ACCGTA 1 -- us2k122Minor allele frequency- A:0.35NS EA NA CSA WA 2055
    rs2002533671,2
    --17864560(+) CTCTT-/AAAAAA 1 -- us2k10--------
    rs2014293071,2
    --17864571(+) AAAAC-/AAAG  
            
    AAAGA
    1 -- us2k10--------
    rs1813739141,2
    --17864574(+) ACAAAC/GAAAGA 1 -- us2k10--------
    rs1995234421,2
    --17864579(+) GAAAG-/AAAAAA 1 -- us2k10--------
    rs1856342031,2
    --17864590(+) AACATA/TGCCAA 1 -- us2k10--------
    rs757047151,2
    --17864614(+) GTACAC/TTGTGA 1 -- us2k12Minor allele frequency- T:0.12CSA WA 119
    rs1405756641,2
    --17864730(+) TCAATA/GGACAT 1 -- us2k10--------
    rs1401966481,2
    C,--17864778(+) CTCTC-/CT    
       GTCTG
    CTGTC
    1 -- us2k10--------
    rs788597101,2
    --17864842(+) CACTGG/TTGTCT 1 -- us2k12Minor allele frequency- T:0.11CSA WA 120

    HapMap Linkage Disequilibrium report for ARHGEF10L (17866330 - 18024370 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for ARHGEF10L
         1 CNV: 9876

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ARHGEF10L for disorders           About GeneDecksing

    OMIM gene information: 612494    OMIM disorders: --

    4 diseases for ARHGEF10L:    About MalaCards
    basal cell carcinoma    spasticity    melanoma    carcinoma

    Human Genome Epidemiology (HuGE) Navigator: ARHGEF10L (4 documents)

    Export disorders for ARHGEF10L gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ARHGEF10L gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with ARHGEF10L)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. GrinchGEF--a novel Rho-specific guanine nucleotide exchange factor. (PubMed id 16112081)1, 2, 3 Winkler S....Lutz S. (2005)
    2. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10997877)1, 2, 3 Nagase T.... Ohara O. (2000)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Serum ferritin levels are associated with a distinct p henotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy. (PubMed id 22095909)1 Lange C.M....Bochud P.Y. (2012)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    6. Mutation of ARHGAP9 in patients with coronary spastic angina. (PubMed id 19911011)1 Takefuji M....Kaibuchi K. (2010)
    7. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    8. Common variants on 1p36 and 1q42 are associated with cutaneous basal cell carcinoma but not with melanoma or pigmentation traits. (PubMed id 18849993)1 Stacey S.N....Stefansson K. (2008)
    9. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
    10. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55160 HGNC: 25540 AceView: FLJ10521 Ensembl:ENSG00000074964 euGenes: HUgn55160
    ECgene: ARHGEF10L H-InvDB: ARHGEF10L

    (According to HUGE)
    About This Section
    HUGE: KIAA1626

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ARHGEF10L Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ARHGEF10L Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ARHGEF10L gene:
    Search GeneIP for patents involving ARHGEF10L

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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