ARHGEF10 Gene
protein-coding GIFtS: 55
GCID: GC08P001778
|
|
Rho guanine nucleotide exchange factor (GEF) 10
| |
Aliases
for ARHGEF10 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Rho Guanine Nucleotide Exchange Factor (GEF) 101 2 | | KIAA02941 3 5 | | Gef101 | | GEF102 | | Rho Guanine Nucleotide Exchange Factor 102 |
Export aliases for ARHGEF10 gene to outside databasesPrevious GC identifers: GC08M001714 GC08M002273 GC08P001922 GC08P001759 GC08P001586 |
Summaries
for ARHGEF10 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ARHGEF10:
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli thatwork through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulateRho-dependent signals. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: ARHGA_HUMAN, O15013Function: May play a role in developmental myelination of peripheral nerves
Gene Wiki entry for ARHGEF10
|
Genomic Views
for ARHGEF10 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_023736.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ARHGEF10 gene promoter:
ISGF-3 Nkx2-2 MIF-1 XBP-1 Nkx5-1 Max N-Myc Pax-4a NF-Y CBF(2)
Other transcription factors
Search SABiosciences Chromatin IP Primers for ARHGEF10
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARHGEF10 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8p23 Ensembl cytogenetic band: 8p23.3 HGNC cytogenetic band: 8p23ARHGEF10 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08P001778: view genomic region
(about GC identifiers)
Start:
|
1,772,142 bp from pter |
End:
|
1,906,807 bp from pter |
Size:
|
134,666 bases |
Orientation:
|
plus strand |
|
Proteins
for ARHGEF10 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ARHGA_HUMAN, O15013 (See
protein sequence)Recommended Name: Rho guanine nucleotide exchange factor 10 Size: 1369 amino acids; 151612 Da
Sequence caution: Sequence=AAH36809.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact;Sequence=AAH40474.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact; Sequence=BAA20754.2;Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=CAH18365.1; Type=Erroneous termination;Positions=895; Note=Translated as Lys;
Secondary accessions: O14665 Q2KHR8 Q68D55 Q8IWD9 Q8IY77Alternative splicing: 5 isoforms: O15013-1 O15013-6 O15013-7 O15013-4 O15013-5 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ARHGEF10: NX_O15013
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O15013
ARHGEF10 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055444.2
ENSEMBL proteins: ENSP00000340297 ENSP00000427909 ENSP00000431012 ENSP00000427768 ENSP00000381571 ENSP00000262112 ENSP00000381568
Human Recombinant Protein Products for ARHGEF10:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
ARHGEF10 for ontologies About GeneDecksing
ARHGEF10 Antibody Products:
Assay Products for ARHGEF10: |
Protein
Domains /
Families
for ARHGEF10 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ARHGEF10 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O15013ProtoNet protein and cluster: O15013 1 Blocks protein family: IPB000219 DH domain
UniProtKB/Swiss-Prot: ARHGA_HUMAN, O15013Similarity: Contains 1 DH (DBL-homology) domain |
Function
for ARHGEF10 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ARHGA_HUMAN, O15013Function: May play a role in developmental myelination of peripheral nerves Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ARHGEF10 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGEF10 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGEF10 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ARHGEF10 (NM_014629) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ARHGEF10 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARHGEF10 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGEF10 |
|
Pathways & Interactions
for ARHGEF10 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/15 super-pathways (see all 15) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | GPCR Pathway | | | 2 | G-AlphaQ Signaling | | | 3 | Rho Family GTPases | | | 4 | CCR3 Pathway in Eosinophils | | | 5 | Signaling by Slit | |
5/21 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for ARHGEF10 (see all 21)
1  BioSystems Pathway for ARHGEF10
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ARHGEF10
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
2 Interacting proteins for ARHGEF10 (O150133 ENSP000003402974) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
ARHGEF10 for ontologies About GeneDecksing
|
Drugs & Compounds
for ARHGEF10 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ARHGEF10
Search CenterWatch for drugs/clinical trials and news about ARHGEF10 / ARHGA
|
Transcripts
for ARHGEF10 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ARHGEF10 gene: NM_014629.2 Unigene Cluster for ARHGEF10: Rho guanine nucleotide exchange factor (GEF) 10 Hs.98594 [show with all ESTs]Unigene Representative Sequence: CR74957016 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000349830(uc003wpr.3) ENST00000520359(uc003wps.3 uc010lre.3)
ENST00000518288(uc003wpq.1) ENST00000382795 ENST00000520972(uc003wpt.3)
ENST00000522969(uc010lrd.2 uc003wpu.3) ENST00000523711(uc003wpv.3)
ENST00000522435 ENST00000524212 ENST00000519641 ENST00000523596 ENST00000523980
ENST00000521927 ENST00000398564 ENST00000262112 ENST00000398560
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGEF10 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGEF10 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ARHGEF10 (NM_014629) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ARHGEF10 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARHGEF10 |
Additional cDNA sequence: AB002292.2 AF009205.1 AK309799.1 AL137508.1 BC026965.1 BC036809.1 BC040474.1 BC047307.1 BC112926.1 CR749570.1 11 DOTS entries: DT.114361 DT.100816211 DT.95164764 DT.65287948 DT.75113013 DT.95164761 DT.97811311 DT.97820408 DT.114362 DT.121489516 DT.99964675 24/179 AceView cDNA sequences (see all 179): AW137967 AB002292 BQ882509 CR622006 BU754567 AL042034 AA400480 BU178611 AU134444 AI367567 AI348138 BU153547 BC040474 CD514846 BQ670124 CA439504 N53385 BU630774 AW873746 AW594315 BQ719438 BQ002527 NM_014629 AI023253
GeneLoc Exon Structure
5/18 Alternative Splicing Database (ASD) splice patterns (SP) for ARHGEF10 (see all 18) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b | · | 13c | · | 13d | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 18a | · | 18b | ^ | 19 | ^ | 20a | · | 20b | · | 20c | ^ | 21a | · | 21b | ^ | 22a | · | 22b | ^ | 23a | · | 23b | ^ | 24a | · | 24b | ^ | 25a | · | 25b | ^ | 26 | ^ | 27a | · | 27b | ^ | 28 | ^ | 29 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ARHGEF10
|
Expression
for ARHGEF10 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ARHGEF10 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGAAAGTGAT
About this image
See ARHGEF10 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ARHGEF10
SOURCE GeneReport for Unigene cluster: Hs.98594
SABiosciences Custom PCR Arrays for ARHGEF10
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ARHGEF10
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ARHGEF10 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARHGEF10 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARHGEF10 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGEF10 |
Orthologs
for ARHGEF10 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ARHGEF10 gene from 6/13 species (see all 13) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Arhgef101 , 5 |
Rho guanine nucleotide exchange factor (GEF) 101, 5 |
79.26(n)1
81.03(a)1 |
|
8 (7.59 cM)5
2340941 NM_172751.21 NP_766339.21
149116635 |
chicken
(Gallus gallus) |
Aves |
ARHGEF101 |
Rho guanine nucleotide exchange factor (GEF) 10 |
72.94(n)
77.29(a) |
|
421900 XM_001235642.2 XP_001235643.2 |
lizard
(Anolis carolinensis) |
Reptilia |
ARHGEF106 |
-- |
72(a) |
1 ↔ 1 |
1(158595480-158708000) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.83772 |
Xenopus laevis transcribed sequence with weak similarity more |
74.09(n) |
|
48013129 |
zebrafish
(Danio rerio) |
Actinopterygii |
570444962 |
-- |
72.39(n) |
|
57044496 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG85573 |
-- |
28(a) |
|
-- |
ENSEMBL Gene Tree for ARHGEF10 (if available)
TreeFam Gene Tree for ARHGEF10 (if available) |
Paralogs
for ARHGEF10 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ARHGEF10 gene
- ECT22 SPAG92 ARHGEF172 ARHGEF10L2 MAPK8IP32
2 SIMAP similar genes for ARHGEF10 using alignment to 3 protein entries: ARHGA_HUMAN (see all proteins):DKFZp761P221 ARHGEF10L
ARHGEF10 for paralogs About GeneDecksing
|
Genomic Variants
for ARHGEF10 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ARHGEF10 (1772142 - 1906807 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 45 variations for ARHGEF10
13 CNVs: 82402 43362 70199 70201 70202 70203 70200 95135 95134 95132 70204 53176 100245
15/32 Indels (see all 32): 95141 82406 82404 60688 13000 95133 95128 95136 82405 28880 95130 82403 28876 42069 42946
Human Gene Mutation Database (HGMD): ARHGEF10
Locus Specific Mutation Databases (LSDB): ARHGEF10
| SABiosciences Cancer Mutation PCR Assays |
| 1 SABiosciences qBiomarker Copy Number PCR Array containing ARHGEF10: |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ARHGEF10 |
|
Disorders
/ Diseases
for ARHGEF10 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ARHGEF10 for disorders About GeneDecksing
OMIM gene information: 608136
OMIM disorders: 608236
UniProtKB/Swiss-Prot: ARHGA_HUMAN, O15013
Defects in ARHGEF10 are the cause of slowed nerve conduction velocity (SNCV) [MIM:608236]. Affectedindividuals present a reduction in nerve conduction velocities without any clinical signs of peripheral or centralnervous system dysfunction. SNCV inheritance is autosomal dominant
6  diseases for ARHGEF10: About MalaCardsslowed nerve conduction velocity, ad slowed nerve conduction velocity schizophrenia breast cancer
adenocarcinoma pancreatitis
Human Genome Epidemiology (HuGE) Navigator: ARHGEF10 (4 documents)
Export disorders for ARHGEF10 gene to outside databases
|
Publications
for ARHGEF10 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ARHGEF10 gene, integrated from 9 sources (see all 20):
(articles sorted by number of sources associating them with ARHGEF10) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)1, 2, 3 Nagase T.... Ohara O. (1997)
- Gef10--the third member of a Rho-specific guanine nuc leotide exchange factor subfamily with unusual protein architecture. (PubMed id 16896804)1, 3 Mohl M....Lutz S. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Slowed conduction and thin myelination of peripheral nerves associated with mutant rho Guanine-nucleotide exchange factor 10. (PubMed id 14508709)1, 2 Verhoeven K.... Timmerman V. (2003)
- Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
- High-resolution mapping and transcript identification at the progressive epilepsy with mental retardation locus on chromosome 8p. (PubMed id 9314494)1, 2 Ranta S....Gilliam T.C. (1997)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
- The functional SNP rs4376531 in the ARHGEF gene is a risk factor for the atherothrombotic stroke in Han Chinese. (PubMed id 21743172)1 Yin Y.Y....He L. (2011)
- Identification of a negative regulatory region for th e exchange activity and characterization of T332I mutant of Rho guanine nucleot ide exchange factor 10 (ARHGEF10). (PubMed id 21719701)1 Chaya T....Inagaki S. (2011)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
|
External Searches for ARHGEF10 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ARHGEF10 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ARHGEF10 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ARHGEF10 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ARHGEF10 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ARHGEF10 gene:
Search GeneIP for patents involving ARHGEF10
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ARHGEF10 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ARHGEF10 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ARHGEF10 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ARHGEF10 | | OriGene 3'-UTR Clone for ARHGEF10 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGEF10 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGEF10 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ARHGEF10 | | OriGene Custom Protein Services for ARHGEF10 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ARHGEF10 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ARHGEF10 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARHGEF10 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ARHGEF10 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARHGEF10 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARHGEF10 |
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 | | | ARHGEF10 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGEF10 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for ARHGEF10 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARHGEF10 |
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