Aliases for ARHGEF10 Gene
External Ids for ARHGEF10 Gene
Previous GeneCards Identifiers for ARHGEF10 Gene
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. [provided by RefSeq, Jul 2008]
GeneCards Summary for ARHGEF10 Gene
ARHGEF10 (Rho Guanine Nucleotide Exchange Factor (GEF) 10) is a Protein Coding gene. Diseases associated with ARHGEF10 include slowed nerve conduction velocity, ad. Among its related pathways are RhoGDI Pathway and ERK Signaling. GO annotations related to this gene include Rho guanyl-nucleotide exchange factor activity and kinesin binding. An important paralog of this gene is ARHGEF10L.
UniProtKB/Swiss-Prot for ARHGEF10 Gene
May play a role in developmental myelination of peripheral nerves.