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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ARHGAP9 Gene

protein-coding GIFtS: 60
GCID: GC12M057866

Rho GTPase activating protein 9

Explore 2 diseases affiliated with
ARHGAP9 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Rho GTPase Activating Protein 9¹ ²
10C¹ ²
Rho-Type GTPase-Activating Protein 9² ³
MGC1295¹
RGL1²
Rho GTPase-Activating Protein 9²

External Ids:	HGNC: 14130¹	Entrez Gene: 64333²	Ensembl: ENSG00000123329⁷	OMIM: 610576⁵	UniProtKB: Q9BRR9³

Export aliases for ARHGAP9 gene to outside databases

Previous GC identifers: GC12M059326 GC12M058009 GC12M057582 GC12M056152 GC12M054903

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ARHGAP9:

This gene encodes a member of the Rho-GAP family of GTPase activating proteins. The protein has substantial GAP

activity towards several Rho-family GTPases in vitro, converting them to an inactive GDP-bound state. It is implicated

in regulating adhesion of hematopoietic cells to the extracellular matrix. Multiple transcript variants encoding

different isoforms have been found for this gene. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: RHG09_HUMAN, Q9BRR9

Function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has a

substantial GAP activity toward CDC42 and RAC1 and less toward RHOA. Has a role in regulating adhesion of

hematopoietic cells to the extracellular matrix

Gene Wiki entry for ARHGAP9

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000012.11 NC_018923.1 NT_029419.12

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ARHGAP9 gene promoter:
NF-1 HSF2 CUTL1 GATA-2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): ARHGAP9 promoter sequence

Search SABiosciences Chromatin IP Primers for ARHGAP9

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARHGAP9

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.3 Ensembl cytogenetic band: 12q13.3 HGNC cytogenetic band: 12q13.3

ARHGAP9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARHGAP9 gene location

GeneLoc information about chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12M057866: view genomic region (about GC identifiers)

Start:	57,866,038 bp from pter	End:	57,882,597 bp from pter
Size:	16,560 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RHG09_HUMAN, Q9BRR9 (See protein sequence)

Recommended Name: Rho GTPase-activating protein 9

Size: 750 amino acids; 83260 Da

Subunit: Interacts with FASLG

3 PDB 3D structures from and Proteopedia for ARHGAP9:

2P0D (3D)

2P0F (3D)

2P0H (3D)

Secondary accessions: B4DVI3 Q8TCJ3 Q8WYR0 Q96EZ2 Q96S74

Alternative splicing: 4 isoforms: Q9BRR9-1 Q9BRR9-2 Q9BRR9-3 Q9BRR9-4

Explore the universe of human proteins at neXtProt for ARHGAP9: NX_Q9BRR9

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9BRR9

ARHGAP9 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (3 alternative transcripts):

NP_001073625.1 NP_001073626.1 NP_115885.2

ENSEMBL proteins:

ENSP00000377380 ENSP00000394307 ENSP00000377386 ENSP00000448404 ENSP00000397950

ENSP00000448423 ENSP00000449829 ENSP00000450256 ENSP00000446932 ENSP00000448424

ENSP00000450223 ENSP00000448358 ENSP00000348782

Reactome Protein details: Q9BRR9
Human Recombinant Protein Products:

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	Uscn Proteins for ARHGAP9

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	--	--
GO:0005829	cytosol	TAS	--

ARHGAP9 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ARHGAP9 for domains About GeneDecksing

5/7 InterPro domains/families (see all 7):

IPR008936 Rho_GTPase_activation_prot

IPR001849 Pleckstrin_homology

IPR001452 SH3_domain

IPR001202 WW_Rsp5_WWP

IPR011993 PH_like_dom

Graphical View of Domain Structure for InterPro Entry Q9BRR9

ProtoNet protein and cluster: Q9BRR9

3 Blocks protein families:

IPB000198 RhoGAP domain

IPB001452 SH3 domain signature

IPB001849 Pleckstrin-like

UniProtKB/Swiss-Prot: RHG09_HUMAN, Q9BRR9

Similarity: Contains 1 PH domain

Similarity: Contains 1 Rho-GAP domain

Similarity: Contains 1 SH3 domain

Similarity: Contains 1 WW domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: RHG09_HUMAN, Q9BRR9

Function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has a

substantial GAP activity toward CDC42 and RAC1 and less toward RHOA. Has a role in regulating adhesion of

hematopoietic cells to the extracellular matrix

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		hsa-miR-30c-2* hsa-miR-30c-1*
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Products:

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGAP9

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005096	GTPase activator activity	IDA	11396949
GO:0005543	phospholipid binding	IEA	--

ARHGAP9 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for ARHGAP9:

Increased gamma-H2AX phosphory

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

G-protein signaling Regulation of RAC1 activity

G-protein signaling Regulation of RAC1 activity

1.00

G-protein signaling_Regulation of RAC1 activity

0.88

Cell death signalling via NRAGE, NRIF and NADE

Rho GTPase cycle

0.25

Signaling by Rho GTPases

0.25

Regulation of RhoA activity

Regulation of RhoA activity

1.00

Regulation of RAC1 activity

Regulation of RAC1 activity

1.00

Signaling by GPCR

Signal Transduction

0.56

Pathway sources
See GeneCards unified pathways
Show all pathways

1 EMD Millipore Pathway for ARHGAP9

G-protein signaling Regulation of RAC1 activity

1 GeneGo (Thomson Reuters) Pathway for ARHGAP9

G-protein signaling Regulation of RAC1 activity

2 BioSystems Pathways for ARHGAP9

	Regulation of RhoA activity
	Regulation of RAC1 activity

3 Reactome Pathways for ARHGAP9

	Signaling by Rho GTPases
	Signal Transduction
	Rho GTPase cycle

ARHGAP9 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for ARHGAP9

STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

5/6 Interacting proteins for ARHGAP9 (Q9BRR9^{2, 3} ENSP00000377380⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 6)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
RBPMS	Q93062²^,³, ENSP00000340176⁴	MINT-67740 I2D: score=5 STRING: ENSP00000340176
SMAD9	O15198²^,³	MINT-62091 I2D: score=3
MAPK1	P28482³, ENSP00000215832⁴	I2D: score=1 STRING: ENSP00000215832
MAPK14	Q16539³, ENSP00000229794⁴	I2D: score=1 STRING: ENSP00000229794
FASLG	P48023³, ENSP00000356694⁴	I2D: score=1 STRING: ENSP00000356694

About this table

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007165	signal transduction	--	--
GO:0007264	small GTPase mediated signal transduction	TAS	--
GO:0043547	positive regulation of GTPase activity	IDA	11396949
GO:0051056	regulation of small GTPase mediated signal transduction	TAS	--

ARHGAP9 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ARHGAP9
Search CenterWatch for drugs/clinical trials and news about ARHGAP9 / RHG09

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ARHGAP9 gene (3 alternative transcripts):

NM_001080156.1 NM_001080157.1 NM_032496.2

Unigene Cluster for ARHGAP9:

Rho GTPase activating protein 9

Hs.437126 [show with all ESTs]

Unigene Representative Sequence: BC006107

18/25 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 25):

ENST00000393791(uc001sny.3 uc001soc.3) ENST00000552953 ENST00000424809(uc001sob.3)

ENST00000393797(uc001sod.3 uc001soe.1) ENST00000550399 ENST00000546200(uc001soa.3)

ENST00000550288 ENST00000430041(uc001snz.3) ENST00000550440 ENST00000550130

ENST00000546704 ENST00000548139 ENST00000548148 ENST00000550454 ENST00000547200

ENST00000552604 ENST00000552420(uc010sro.1) ENST00000551574

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Additional cDNA sequence:

AB030239.1 AB051853.1 AK092763.1 AK131415.1 AK300910.1 AK301095.1 AK304107.1 BC006107.1

BC011820.1

18 DOTS entries:

DT.121187579 DT.100778195 DT.100756375 DT.121187383 DT.121187411 DT.206685 DT.40106320 DT.95168316

DT.100022468 DT.121187562 DT.40109252 DT.102841105 DT.95197306 DT.95089157 DT.100778193 DT.91671832

DT.100768213 DT.95168317

24/97 AceView cDNA sequences (see all 97):

BC011820 BC006107 NM_032496 BQ574628 CR618863 BI830251 CR610490 AA446809

AB051853 BQ072642 AK092763 AX747713 AI708450 AL548053 AL713803 BX119308

CA446019 CB528354 AA768356 AW170239 AI954871 AK131415 BM925075 AW411108

GeneLoc Exon Structure

5/21 Alternative Splicing Database (ASD) splice patterns (SP) for ARHGAP9 (see all 21) About this scheme

ExUns:	1	^	2a	·	2b	^	3a	·	3b	·	3c	^	4	^	5a	·	5b	^	6a	·	6b	·	6c	·	6d	·	6e	^	7a	·	7b	^	8a	·	8b	·	8c	^	9a	·	9b	·	9c	^	10a	·	10b	·	10c	^	11a	·
SP1:			-								-		-		-		-		-		-		-		-		-										-						-		-
SP2:											-		-		-		-		-		-		-		-		-										-						-		-
SP3:																																					-						-		-
SP4:
SP5:																			-		-		-		-		-										-						-		-

ExUns:	11b	^	12	^	13a	·	13b	^	14	^	15	^	16a	·	16b	·	16c	^	17	^	18a	·	18b	^	19	^	20	^	21
SP1:													-										-
SP2:													-										-				-
SP3:													-										-
SP4:													-										-
SP5:

ECgene alternative splicing isoforms for ARHGAP9

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ARHGAP9 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTATTTTTAA

About this image

ARHGAP9 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Skeletal Muscle

Extraocular Muscles

Skeletal Muscle

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See ARHGAP9 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ARHGAP9

SOURCE GeneReport for Unigene cluster: Hs.437126

UniProtKB/Swiss-Prot: RHG09_HUMAN, Q9BRR9

Tissue specificity: Predominantly expressed in peripheral blood leukocytes, spleen, and thymus

SABiosciences Custom PCR Arrays for ARHGAP9

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		Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARHGAP9

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGAP9

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for ARHGAP9 gene from 3/14 species (see all 14) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
lizard (Anolis carolinensis)	Reptilia	ARHGAP9⁶	--	44(a)	1 ↔ 1	GL343212.1(628646-658117)
zebrafish (Danio rerio)	Actinopterygii	CABZ01088365.1⁶	--	42(a)	1 ↔ 1	6(58911056-58962125)
worm (Caenorhabditis elegans)	Secernentea	C38D4.5³	chimaerin	30(a)		III(4868704-4874366) --

ENSEMBL Gene Tree for ARHGAP9 (if available)
TreeFam Gene Tree for ARHGAP9 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for ARHGAP9 gene

HMHA1² ARHGAP21² ARHGAP27² CHN2² ARHGAP10² ARHGAP23² ARHGAP29² ARHGAP26²

CHN1² ARHGAP15² ARHGAP12² OPHN1² GMIP² ARHGAP42²

18/41 SIMAP similar genes for ARHGAP9 using alignment to 11 protein entries: RHG09_HUMAN (see all proteins) (see all similar genes):

ARHGAP15 ARHGAP12 ARHGAP32 DKFZp451F1115 RICS ARHGAP5

ARAP3 ARHGAP18 ARHGAP30 CHN1 ARHGAP27 ARHGAP1

ARHGAP40 ARHGAP8 BPGAP1 ARHGAP33 FKSG42 MYO9A

ARHGAP9 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 12 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs11544238^1,2	C,F,H,	other	57870155(-)	`CCTCCT/GCAGGC`	6	/A /S	mis¹		20		NS EA NA EU	7455
rs35945970^1,2	C,F,	--	54904802(+)	`TTTGAC/TGGGCA`	3	--	int¹		3		WA NA	124
rs34937298^1,2		--	54904994(+)	`GAACCC/TGGGAG`	3	--	int¹		0	--	--	--	--
rs2280140^1,2	H	--	54905663(+)	`TCCCCC/TACATC`	3	--	int¹		4		NS EA	406
rs113759971^1,2		--	54905988(+)	`GGACAA/GCCCTC`	3	--	int¹		0	--	--	--	--
rs2277316^1,2	C,F,A,H,	--	54907360(-)	`CGGGAC/TGTGGG`	3	--	int¹		24		NS EA NA WA CSA	2355
rs3216740^1,2	C,F,	--	54907405(-)	`GCAGT-/TGGGGG`	3	--	int¹		3		NA CSA	6
rs509941^1,2	C,F	--	54908251(+)	`CCTGAG/CCTTGC`	6	/L /V	mis¹		6		EA NA MN	244
rs509962^1,2	C	--	54908252(+)	`CTGAGC/GTTGCG`	6	N K	mis¹		1		MN	184
rs35090815^1,2	C,F	--	54908599(+)	`GTGCGT/CTGGCT`	6	/Q	syn¹		2		NA	4602

HapMap Linkage Disequilibrium report for ARHGAP9 (57866038 - 57882597 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for ARHGAP9
3 CNVs: 58585 58584 3891
Human Gene Mutation Database (HGMD): ARHGAP9

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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ARHGAP9 for disorders           About GeneDecksing

OMIM gene information: 610576    OMIM disorders: --

2 diseases for ARHGAP9:    About MalaCards

coronary artery spasm 3 spasticity

Human Genome Epidemiology (HuGE) Navigator: ARHGAP9 (2 documents)

Export disorders for ARHGAP9 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for ARHGAP9 gene, integrated from 9 sources (see all 17):
(articles sorted by number of sources associating them with ARHGAP9)

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Isolation of a novel human gene, ARHGAP9, encoding a rho-GTPase activating protein. (PubMed id 11396949)^{1, 2, 3, 9} Furukawa Y.... Nakamura Y. (2001)
Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening. (PubMed id 19807924)^{1, 2} Voss M....Janssen O. (2009)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)¹ Udeshi N.D....Carr S.A. (2012)
A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (2011)
Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)¹ OlA!h J....OvA!di J. (2011)
Mutation of ARHGAP9 in patients with coronary spastic angina. (PubMed id 19911011)¹ Takefuji M....Kaibuchi K. (2010)
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)² Mayya V.... Han D.K. (2009)
ArhGAP9, a novel MAP kinase docking protein, inhibits Erk and p38 activation through WW domain binding. (PubMed id 17284314)¹ Ang B.K....Ong S.H. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 64333	HGNC: 14130	AceView: ARHGAP9	Ensembl:ENSG00000123329	euGenes: HUgn64333
ECgene: ARHGAP9	H-InvDB: ARHGAP9

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for ARHGAP9	Pharmacogenomics, SNPs, Pathways

Intellectual Property for ARHGAP9 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for ARHGAP9 gene:
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ARHGAP9 Gene

Rho GTPase activating protein 9

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Rho GTPase activating protein 9

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