Aliases for ARHGAP5 Gene
External Ids for ARHGAP5 Gene
Previous HGNC Symbols for ARHGAP5 Gene
Previous GeneCards Identifiers for ARHGAP5 Gene
Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for ARHGAP5 Gene
ARHGAP5 (Rho GTPase Activating Protein 5) is a Protein Coding gene. Among its related pathways are G-protein signaling_Regulation of CDC42 activity and Regulation of RhoA activity. GO annotations related to this gene include GTP binding and GTPase activator activity. An important paralog of this gene is ARHGAP35.
UniProtKB/Swiss-Prot for ARHGAP5 Gene
GTPase-activating protein for Rho family members. May play a role in the reduction of the p21rasGTPase-activating potential of RASA1/p120GAP.