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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ARHGAP5 Gene

protein-coding GIFtS: 61
GCID: GC14P032546

Rho GTPase activating protein 5

(Previous name: growth factor independent 2 )
(Previous symbol: GFI2)

Explore 5 diseases affiliated with
ARHGAP5 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Rho GTPase Activating Protein 5¹ ²		Rho-Type GTPase-Activating Protein 5² ³
P190-B¹		RHOGAP5³ ⁵
GFI2¹ ²		P100 RasGAP-Associated P105 Protein²
RhoGAP5¹ ²		P105 RhoGAP²
Growth Factor Independent 2¹ ²		Rho GTPase-Activating Protein 5²
P190BRhoGAP¹

External Ids:	HGNC: 675¹	Entrez Gene: 394²	Ensembl: ENSG00000100852⁷	OMIM: 602680⁵	UniProtKB: Q13017³

Export aliases for ARHGAP5 gene to outside databases

Previous GC identifers: GC14P030000 GC14P026333 GC14P030536 GC14P031615 GC14P012663

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ARHGAP5:

Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by

stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this

gene. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: RHG05_HUMAN, Q13017

Function: GTPase-activating protein for Rho family members. May play a role in the reduction of the

p21rasGTPase-activating potential of RASA1/p120GAP

Gene Wiki entry for ARHGAP5

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000014.8 NC_018925.1 NT_026437.12

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ARHGAP5 gene promoter:
CREB LHX3b/Lhx3b STAT1 Nkx2-2 deltaCREB Pax-4a Evi-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ARHGAP5 promoter sequence

Search SABiosciences Chromatin IP Primers for ARHGAP5

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARHGAP5

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q12 Ensembl cytogenetic band: 14q12 HGNC cytogenetic band: 14q12

ARHGAP5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARHGAP5 gene location

GeneLoc information about chromosome 14 GeneLoc Exon Structure

GeneLoc location for GC14P032546: view genomic region (about GC identifiers)

Start:	32,545,320 bp from pter	End:	32,628,934 bp from pter
Size:	83,615 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RHG05_HUMAN, Q13017 (See protein sequence)

Recommended Name: Rho GTPase-activating protein 5

Size: 1502 amino acids; 172460 Da

Subcellular location: Cytoplasm. Membrane; Peripheral membrane protein. Note=Also membrane-associated when found in

fibrillar patterns that colocalize with the alpha5-beta1 integrin receptor (ITGA5/ITGB1) for fibronectin

Sequence caution: Sequence=AAA95963.1; Type=Frameshift; Positions=Several; Sequence=AAH32723.1; Type=Miscellaneous

discrepancy; Note=Contaminating sequence. Potential poly-A sequence;

2 PDB 3D structures from and Proteopedia for ARHGAP5:

2EE4 (3D)

2EE5 (3D)

Secondary accessions: A1L375 A1L376 A8KAA1 D3DS89 D3DS90 Q05BE8 Q05BU8 Q59ER0 Q6DHZ3

Alternative splicing: 4 isoforms: Q13017-1 Q13017-2 Q13017-3 Q13017-4 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ARHGAP5: NX_Q13017

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q13017

ARHGAP5 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001025226.1 NP_001164.2

ENSEMBL proteins:

ENSP00000452372 ENSP00000452222 ENSP00000441692 ENSP00000379827 ENSP00000407395

ENSP00000451579 ENSP00000451061 ENSP00000452606 ENSP00000371897 ENSP00000393307

Reactome Protein details: Q13017
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	Uscn Proteins for ARHGAP5

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	--	--
GO:0005737	cytoplasm	TAS	8537347
GO:0005829	cytosol	TAS	--
GO:0016020	membrane	IEA	--

ARHGAP5 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ARHGAP5 for domains About GeneDecksing

4 InterPro domains/families:

IPR002713 FF_domain

IPR008936 Rho_GTPase_activation_prot

IPR001806 Small_GTPase

IPR000198 RhoGAP_dom

Graphical View of Domain Structure for InterPro Entry Q13017

ProtoNet protein and cluster: Q13017

2 Blocks protein families:

IPB000198 RhoGAP domain

IPB002713 FF domain

UniProtKB/Swiss-Prot: RHG05_HUMAN, Q13017

Similarity: Contains 4 FF domains

Similarity: Contains 1 Rho-GAP domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: RHG05_HUMAN, Q13017

Function: GTPase-activating protein for Rho family members. May play a role in the reduction of the

p21rasGTPase-activating potential of RASA1/p120GAP

Genatlas biochemistry entry for ARHGAP5:

Rho/GTPase activating protein 5,expressed in a variety of cells,located diffusely in the cytoplasm

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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGAP5

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003924	GTPase activity	TAS	8537347
GO:0005100	Rho GTPase activator activity	TAS	8537347
GO:0005525	GTP binding	IEA	--
GO:0042169	SH2 domain binding	IPI	1689011

ARHGAP5 for ontologies About GeneDecksing

2 GenomeRNAi human phenotypes for ARHGAP5:

Decreased focal adhesion (FA)

Decreased viability of wild-ty

Animal Models:
Mouse knock-out Arhgap5^tm1Jset for ARHGAP5
9 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Arhgap5):

adipose tissue	endocrine/exocrine gland	growth/size	hematopoietic system	immune system
integument	mortality/aging	nervous system	respiratory system

ARHGAP5 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/14 super-pathways (see all 14) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Focal Adhesion

Focal Adhesion

1.00

Focal adhesion

0.66

G-protein signaling Regulation of RAC1 activity

G-protein signaling Regulation of CDC42 activity

0.25

G-protein signaling_Regulation of CDC42 activity

0.25

Cell death signalling via NRAGE, NRIF and NADE

Rho GTPase cycle

0.25

Signaling by Rho GTPases

0.25

IL-9 Signaling Pathways

G-protein signaling Cross-talk between Ras-family GTPases

0.14

G-protein signaling_Cross-talk between Ras-family GTPases

0.14

Cytoskeletal Signaling

Cytoskeletal Signaling

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

2 EMD Millipore Pathways for ARHGAP5

	G-protein signaling Regulation of CDC42 activity
	G-protein signaling Cross-talk between Ras-family GTPases

5 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for ARHGAP5

	RhoA Pathway
	G12-G13 in Cellular Signaling
	RhoGDI Pathway
	Transendothelial Migration of Leukocytes
	Ras Pathway

1 Cell Signaling Technology (CST) Pathway for ARHGAP5

Cytoskeletal Signaling

2 GeneGo (Thomson Reuters) Pathways for ARHGAP5

	G-protein signaling Cross-talk between Ras-family GTPases
	G-protein signaling Regulation of CDC42 activity

3 BioSystems Pathways for ARHGAP5

	Focal Adhesion
	RAC1 signaling pathway
	Regulation of RhoA activity

3 Reactome Pathways for ARHGAP5

	Signaling by Rho GTPases
	Signal Transduction
	Rho GTPase cycle

2 Kegg Pathways (Kegg details for ARHGAP5):

	Focal adhesion
	Leukocyte transendothelial migration

ARHGAP5 for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for ARHGAP5

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/50 Interacting proteins for ARHGAP5 (Q13017^{2, 3} ENSP00000371897⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 50)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SMURF2	Q9HAU4²^,³	MINT-61793 I2D: score=4
RASA1	P20936³, ENSP00000274376⁴	I2D: score=3 STRING: ENSP00000274376
PTK2B	Q14289³, ENSP00000332816⁴	I2D: score=2 STRING: ENSP00000332816
RHOA	P61586³, ENSP00000400175⁴	I2D: score=2 STRING: ENSP00000400175
RND1	Q92730³, ENSP00000308461⁴	I2D: score=1 STRING: ENSP00000308461

About this table

Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0002053	positive regulation of mesenchymal cell proliferation	IEA	--
GO:0006184	GTP catabolic process	TAS	8537347
GO:0007155	cell adhesion	TAS	8537347
GO:0007165	signal transduction	--	--
GO:0007264	small GTPase mediated signal transduction	TAS	--

ARHGAP5 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ARHGAP5
Search CenterWatch for drugs/clinical trials and news about ARHGAP5 / RHG05

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ARHGAP5 gene (2 alternative transcripts):

NM_001030055.1 NM_001173.2

Unigene Cluster for ARHGAP5:

Rho GTPase activating protein 5

Hs.592313 [show with all ESTs]

Unigene Representative Sequence: NM_001030055

11 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000555814 ENST00000556611 ENST00000539826 ENST00000396582 ENST00000433497

ENST00000556191 ENST00000554090 ENST00000557643 ENST00000216743 ENST00000345122(uc001wrl.3 uc001wrn.3)

ENST00000432921(uc001wrm.3 uc001wro.3 uc001wrp.3)

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Additional cDNA sequence:

AB209751.1 AK023014.1 AK023468.1 AK292966.1 AK307454.1 AY316523.1 BC032723.2 BC050059.1

BC075799.1 BC129928.1 BC129929.1 U17032.1

11 DOTS entries:

DT.443531 DT.95138928 DT.97799782 DT.91915557 DT.101971713 DT.40120106 DT.100725656 DT.120787789

DT.92434681 DT.95330255 DT.91743594

24/136 AceView cDNA sequences (see all 136):

CB134399 AL708500 AI570955 CR596496 R79286 BM676162 BC050059 BC075799

AW088534 BU153875 AI650272 AL045112 CB068360 CB133879 N41589 AL041694

CA394541 BP349859 BF438091 AW295718 AI587378 BM712978 BX486747 BE018303

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ARHGAP5 (see all 6) About this scheme

ExUns:	1	^	2	^	3	^	4a	·	4b	^	5a	·	5b	·	5c	^	6a	·	6b	^	7	^	8	^	9	^	10a	·	10b	·	10c
SP1:
SP2:																	-		-
SP3:					-		-		-		-		-		-		-		-
SP4:
SP5:			-		-

ECgene alternative splicing isoforms for ARHGAP5

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ARHGAP5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCTGGCAAAG

About this image

ARHGAP5 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Lung

Lung Bud

Lung

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See ARHGAP5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ARHGAP5

SOURCE GeneReport for Unigene cluster: Hs.592313

UniProtKB/Swiss-Prot: RHG05_HUMAN, Q13017

Tissue specificity: Expressed in kidney, brain, liver and lung

SABiosciences Expression via Pathway-Focused PCR Arrays including ARHGAP5:

Cytoskeleton Regulators in human mouse rat

Focal Adhesions in human mouse rat

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for ARHGAP5 gene from 6/19 species (see all 19) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	ARHGAP5¹	Rho GTPase activating protein 5	83.98(n) 91.41(a)		428883 XM_426439.3 XP_426439.1
lizard (Anolis carolinensis)	Reptilia	ARHGAP5⁶	--	89(a)	1 ↔ 1	2(56415063-56441582)
African clawed frog (Xenopus laevis)	Amphibia	BX851201.1²	--	72.92(n)		BX851201.1
zebrafish (Danio rerio)	Actinopterygii	arhgap5¹	Rho GTPase activating protein 5	68.52(n) 74.36(a)		795752 XM_001335980.1 XP_001336016.1
fruit fly (Drosophila melanogaster)	Insecta	RhoGAPp190³	mushroom body development Rho GTPase activator	33(a)		16B10 --
worm (Caenorhabditis elegans)	Secernentea	rga-5¹	Protein RGA-5	44.06(n) 30.7(a)		178348 NM_001028086.2 NP_001023257.1

ENSEMBL Gene Tree for ARHGAP5 (if available)
TreeFam Gene Tree for ARHGAP5 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for ARHGAP5 gene

SRGAP1² ARHGAP17² ARHGAP24² ARHGAP22² SRGAP3² ARHGAP35² ARHGAP44² SH3BP1²

ARHGAP4² SRGAP2² ARHGAP25²

18/19 SIMAP similar genes for ARHGAP5 using alignment to 6 protein entries: RHG05_HUMAN (see all proteins) (see all similar genes):

GRLF1 ARHGAP35 ARHGAP27 FAM13B CHN1 CHN2

MYO9A ABR ARHGAP21 ARHGAP4 ARHGAP1 SH3BP1

ARHGAP12 ARHGAP44 ARHGAP24 ARHGAP42 ARHGAP9 OPHN1

ARHGAP5 for paralogs About GeneDecksing

2 Pseudogenes.org Pseudogenes for ARHGAP5
PGOHUM00000235374 PGOHUM00000233237

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 14 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs57278628^1,2	C,	--	32544664(+)	`TCTAAT/CAGATT`	3	--	nc-transcript-variantus2k¹		4		CSA WA NA	241
rs139716108^1,2	C,	--	32544890(+)	`GGAAT-/CCCCCC`	3	--	nc-transcript-variantus2k¹		0	--	--	--	--
rs141724607^1,2		--	32544978(+)	`TTAAGC/TCTCCT`	3	--	nc-transcript-variantus2k¹		0	--	--	--	--
rs114290727^1,2	C,F,	--	32545118(+)	`CACACC/TCAAAG`	3	--	nc-transcript-variantus2k¹		1		WA	118
rs143842231^1,2		--	32545259(+)	`GTCTTC/TTGGGC`	3	--	nc-transcript-variantus2k¹		0	--	--	--	--
rs61730940^1,2	C,F,	--	32545302(+)	`TCCACG/CTCTTG`	3	--	us2k¹ nc-transcript-variant		2		NS EU	655
rs61730944^1,2	C,F,	--	32545316(+)	`TCTCGC/ATCCAC`	3	--	nc-transcript-variantus2k¹		2		NS EU	651
rs150285266^1,2		--	32545635(+)	`GGAACC/TGCGAG`	3	--	nc-transcript-variantus2k¹		0	--	--	--	--
rs186994889^1,2		--	32545736(+)	`TCGGGC/GACGAC`	3	--	nc-transcript-variantus2k¹		0	--	--	--	--
rs192399387^1,2		--	32545762(+)	`AAGGCA/TGTAGC`	3	--	nc-transcript-variantus2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for ARHGAP5 (32545320 - 32628934 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ARHGAP5: --

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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ARHGAP5 for disorders           About GeneDecksing

OMIM gene information: 602680    OMIM disorders: --

5 diseases for ARHGAP5:    About MalaCards

pituitary adenoma adenoma hepatocellular carcinoma breast cancer

carcinoma

Export disorders for ARHGAP5 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for ARHGAP5 gene, integrated from 9 sources (see all 36):
(articles sorted by number of sources associating them with ARHGAP5)

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p190-B, a new member of the Rho GAP family, and Rho are induced to cluster after integrin cross-linking. (PubMed id 8537347)^{1, 2, 3, 9} Burbelo P.D....Yamada Y. (1995)
Nitroproteins from a human pituitary adenoma tissue discovered with a nitrotyrosine affinity column and tandem mass spectrometry. (PubMed id 16777052)^{1, 2} Zhan X. and Desiderio D.M. (2006)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
P190-B, a Rho-GTPase-activating protein, is differentially expressed in terminal end buds and breast cancer. (PubMed id 10939588)^{1, 9} Chakravarty G....Rosen J.M. (2000)
A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (2012)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)² Rigbolt K.T....Blagoev B. (2011)
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)² Olsen J.V....Mann M. (2010)
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)² Mayya V.... Han D.K. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 394	HGNC: 675	AceView: ARHGAP5	Ensembl:ENSG00000100852	euGenes: HUgn394
ECgene: ARHGAP5	Kegg: 394	H-InvDB: ARHGAP5

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for ARHGAP5	Pharmacogenomics, SNPs, Pathways

Intellectual Property for ARHGAP5 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for ARHGAP5 gene:
Search GeneIP for patents involving ARHGAP5

GeneCards and IP:
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Rho GTPase activating protein 5

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Rho GTPase activating protein 5

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