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ARHGAP44 Gene

protein-coding   GIFtS: 53
GCID: GC17P012692

Rho GTPase Activating Protein 44

  Search for ARHGAP44
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Rho GTPase Activating Protein 441 2     RhoGAP Interacting With CIP4 Homologs Protein 22 3
NPC-A-102 3     Rho GTPase-Activating Protein 442
RICH-22 3     Rho GTPase-Activating Protein RICH22
RICH22 3     KIAA06723
Rho-Type GTPase-Activating Protein RICH22 3     

External Ids:    HGNC: 290961   Entrez Gene: 99122   Ensembl: ENSG000000067407   UniProtKB: Q17R893   

Export aliases for ARHGAP44 gene to outside databases

Previous GC identifer: GC17P012588


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ARHGAP44 Gene:
ARHGAP44 (Rho GTPase activating protein 44) is a protein-coding gene. GO annotations related to this gene include GTPase activator activity. An important paralog of this gene is ARHGAP5.

UniProtKB/Swiss-Prot: RHG44_HUMAN, Q17R89
Function: GTPase-activating protein (GAP) that stimulates the GTPase activity of Rho-type GTPases. Thereby,
controls Rho-type GTPases cycling between their active GTP-bound and inactive GDP-bound states. May act as a GAP
for CDC42 and RAC1. Endosomal recycling protein which, in association with SHANK3, is involved in synaptic
plasticity. Promotes GRIA1 exocytosis from recycling endosomes and spine morphological changes associated to
long-term potentiation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NT_010718.17  NC_018928.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for ARHGAP44
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidARHGAP44 promoter sequence
   Search Chromatin IP Primers for ARHGAP44

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ARHGAP44


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p12   Ensembl cytogenetic band:  17p12   HGNC cytogenetic band: 17p12

ARHGAP44 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARHGAP44 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P012692:  view genomic region     (about GC identifiers)

Start:
12,692,829 bp from pter      End:
12,894,960 bp from pter
Size:
202,132 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RHG44_HUMAN, Q17R89 (See protein sequence)
Recommended Name: Rho GTPase-activating protein 44  
Size: 818 amino acids; 89247 Da
Subunit: Interacts with BST2 (via cytoplasmic domain). Interacts (probably via PDZ-binding motif) with SHANK3 (via
PDZ domain); the interaction takes place in dendritic spines and promotes GRIA1 exocytosis
Sequence caution: Sequence=AAP73805.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAP73805.1; Type=Frameshift; Positions=385; Sequence=BAA31647.2; Type=Erroneous initiation;
Note=Translation N-terminally shortened;
Secondary accessions: A8MQB2 O75160 Q7Z5Z7 Q9Y4Q4
Alternative splicing: 2 isoforms:  Q17R89-1   Q17R89-2   (Contains a PDZ-binding motif at positions 764-767)

Explore the universe of human proteins at neXtProt for ARHGAP44: NX_Q17R89

Explore proteomics data for ARHGAP44 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ARHGAP44 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055674.4  
    ENSEMBL proteins: 
     ENSP00000368994   ENSP00000342566   ENSP00000462141   ENSP00000262444   ENSP00000437542  
     ENSP00000463905   ENSP00000465509  
    Reactome Protein details: Q17R89

    ARHGAP44 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for ARHGAP44

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ARHGAP: Rho GTPase activating proteins

    4 InterPro protein domains:
     IPR027267 AH/BAR-dom
     IPR008936 Rho_GTPase_activation_prot
     IPR004148 BAR_dom
     IPR000198 RhoGAP_dom

    Graphical View of Domain Structure for InterPro Entry Q17R89

    ProtoNet protein and cluster: Q17R89

    1 Blocks protein domain: IPB000198 RhoGAP domain

    UniProtKB/Swiss-Prot: RHG44_HUMAN, Q17R89
    Domain: Rho-GAP domain is required to promote GRIA1 exocytosis from recycling endosomes. Rho-GAP and BAR domains
    are necessary for the control of long-term potentiation in hippocampal neurons (By similarity)
    Similarity: Contains 1 BAR domain
    Similarity: Contains 1 Rho-GAP domain


    Find genes that share domains with ARHGAP44           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RHG44_HUMAN, Q17R89
    Function: GTPase-activating protein (GAP) that stimulates the GTPase activity of Rho-type GTPases. Thereby,
    controls Rho-type GTPases cycling between their active GTP-bound and inactive GDP-bound states. May act as a GAP
    for CDC42 and RAC1. Endosomal recycling protein which, in association with SHANK3, is involved in synaptic
    plasticity. Promotes GRIA1 exocytosis from recycling endosomes and spine morphological changes associated to
    long-term potentiation

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005096GTPase activator activity IEA--
    GO:0005515protein binding IPI19273615
    GO:0005543phospholipid binding IDA--
         
    Find genes that share ontologies with ARHGAP44           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for ARHGAP44:
     Increased cell number in G2M,  

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ARHGAP44
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    miRNA
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    miRTarBase miRNAs that target ARHGAP44:
    hsa-mir-30c-5p (MIRT048008), hsa-mir-26b-5p (MIRT029211)

    Block miRNA regulation of human, mouse, rat ARHGAP44 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ARHGAP44 (see all 35):
    hsa-miR-300 hsa-let-7a-2* hsa-miR-138-2* hsa-miR-449a hsa-miR-376a* hsa-miR-3148 hsa-miR-34c-5p hsa-miR-4289
    SwitchGear 3'UTR luciferase reporter plasmidARHGAP44 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ARHGAP44

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGAP44


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RHG44_HUMAN, Q17R89: Cell projection, dendritic spine (By similarity). Recycling endosome (By similarity). Cell
    junction, synapse (By similarity). Note=In CA1 hippocampal synapses, detected at both presynaptic and
    postsynaptic sites (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol4
    mitochondrion2
    nucleus2
    cytoskeleton1
    plasma membrane1

    Gene Ontology (GO): Selected cellular component terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005737cytoplasm ----
    GO:0005829cytosol TAS--
    GO:0030054cell junction IEA--
    GO:0031256leading edge membrane IDA--

    Find genes that share ontologies with ARHGAP44           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ARHGAP44 About    
    See pathways by source

    SuperPathContained pathways About
    1Rho GTPase cycle
    Rho GTPase cycle1.00
    Signaling by Rho GTPases1.00
    2Signaling by GPCR
    Signal Transduction0.58


    Find genes that share SuperPaths with ARHGAP44           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for ARHGAP44
        Rho GTPase cycle


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ARHGAP44
    Interactions:

        Search GeneGlobe Interaction Network for ARHGAP44

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ARHGAP44 (Q17R892, 3 ENSP000003689944) via UniProtKB, MINT, STRING, and/or I2D (see all 37)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HN1Q9UK762, 3, ENSP000003483164MINT-64756 I2D: score=5 STRING: ENSP00000348316
    CDC42P609533, ENSP000003144584I2D: score=1 STRING: ENSP00000314458
    RAC1P630003, ENSP000003484614I2D: score=1 STRING: ENSP00000348461
    ARHGDIAENSP000002693214STRING: ENSP00000269321
    ARHGDIBENSP000002289454STRING: ENSP00000228945
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006887exocytosis IEA--
    GO:0007165signal transduction ----
    GO:0007264small GTPase mediated signal transduction TAS--
    GO:0051056regulation of small GTPase mediated signal transduction TAS--

    Find genes that share ontologies with ARHGAP44           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ARHGAP44 (RHG44)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ARHGAP44 gene: 
    NM_014859.4  

    Unigene Cluster for ARHGAP44:

    Rho GTPase activating protein 44
    Hs.499758  [show with all ESTs]
    Unigene Representative Sequence: NM_014859
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000379672(uc002gnr.4 uc010vvk.2) ENST00000340825(uc010vvl.2 uc010vvm.2 uc010vvn.2)
    ENST00000580768(uc002gns.4) ENST00000262444 ENST00000544416(uc002gnt.1)
    ENST00000578442 ENST00000538915 ENST00000583608 ENST00000578087 ENST00000581437
    ENST00000584974
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate ARHGAP44 (see all 35):
    hsa-miR-300 hsa-let-7a-2* hsa-miR-138-2* hsa-miR-449a hsa-miR-376a* hsa-miR-3148 hsa-miR-34c-5p hsa-miR-4289
    SwitchGear 3'UTR luciferase reporter plasmidARHGAP44 3' UTR sequence
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat ARHGAP44
      QuantiFast Probe-based Assays in human, mouse, rat ARHGAP44

    Additional mRNA sequence: 

    AB014572.1 AK024589.1 AK294538.1 AL080100.1 AL096728.1 AY320403.1 BC022452.1 BC070074.1 
    BC094754.1 BC117412.1 BC117416.1 BC131511.1 BC143852.1 BC143853.1 BC143855.1 BC143856.1 

    9 DOTS entries:

    DT.100754138  DT.311625  DT.120963943  DT.439929  DT.99982564  DT.91746978  DT.95162027  DT.109715 
    DT.120963896 

    Selected AceView cDNA sequences (see all 79):

    AA150724 Z40573 BQ900999 BU731157 NM_014859 BM993036 AL080100 BM856495 
    AI565116 AL118875 AI380830 BM931651 BU788177 AB014572 AA708431 BF476635 
    CK000285 BM694551 R53230 AK023797 CA440189 F06994 BF941624 AL120363 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ARHGAP44 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TACAAATCGT
    ARHGAP44 Expression
    About this image


    ARHGAP44 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 3 entries
             HyStem+TGFbeta3+GDF5-induced MEL2 cells
     
     Cartilage (Muscoskeletal System)    fully expand to see all 2 entries
             HyStem+TGFbeta3+GDF5-induced MEL2 cells
     
     Lung (Respiratory System)
             Alveolar type II cells
     
     Neural Crest (Gastrulation Derivatives)
             PureStem 4D20.8, NCr-fac Progenitor
    ARHGAP44 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ARHGAP44 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.499758

    UniProtKB/Swiss-Prot: RHG44_HUMAN, Q17R89
    Tissue specificity: Highly expressed in brain. Expressed at weak level in other tissues

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGAP44

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ARHGAP44 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Arhgap441 , 5 Rho GTPase activating protein 441, 5 87.97(n)1
    94.54(a)1
      11 (40.42 cM)5
    2168311  NM_001099288.11  NP_001092758.11 
     650020395 
    chicken
    (Gallus gallus)
    Aves ARHGAP441 Rho GTPase activating protein 44 78.28(n)
    83.58(a)
      427797  XM_004946078.1  XP_004946135.1 
    lizard
    (Anolis carolinensis)
    Reptilia ARHGAP446
    Rho GTPase activating protein 44
    81(a)
    1 ↔ 1
    2(105955241-105992727)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC1004972721 rho GTPase-activating protein 44-like 70.1(n)
    77.9(a)
      100497272  XM_002937019.2  XP_002937065.2 
    zebrafish
    (Danio rerio)
    Actinopterygii si:ch211-114m9.11 si:ch211-114m9.1 71.51(n)
    76.09(a)
      567298  XM_005163785.1  XP_005163842.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RhoGAP92B6
    RhoGAP92B
    27(a)
    1 → many
    3R(15730861-15739452)
    worm
    (Caenorhabditis elegans)
    Secernentea Y34B4A.86
    Protein Y34B4A.8, isoform b
    25(a)
    1 → many
    X(5271843-5275282) WBGene00021324


    ENSEMBL Gene Tree for ARHGAP44 (if available)
    TreeFam Gene Tree for ARHGAP44 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ARHGAP44 gene
    ARHGAP52  ARHGAP172  SRGAP12  ARHGAP242  ARHGAP222  SRGAP32  ARHGAP352  SH3BP12  
    ARHGAP252  SRGAP22  ARHGAP42  
    12 SIMAP similar genes for ARHGAP44 using alignment to 7 protein entries:     RHG44_HUMAN (see all proteins):
    RICH2    ARHGAP17    CHN2    ARHGAP12    ARHGAP23    ABR
    ARHGAP31    SH3BP1    ARHGAP21    ARHGAP24    ARHGAP5    ARHGAP9

    Find genes that share paralogs with ARHGAP44           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ARHGAP44 (see all 4651)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs80642821,2
    C,F,A--12690902(+) tttacA/Gatccc 1 -- us2k16Minor allele frequency- G:0.26NA WA EA 364
    rs1472051671,2
    --12691409(+) TATAAA/GATTAG 1 -- us2k10--------
    rs744103181,2
    --12691478(+) TAAATA/GAATAC 1 -- us2k10--------
    rs1911549961,2
    --12691712(+) TTTTAC/GTTGAT 1 -- us2k10--------
    rs780206481,2
    C,F--12691753(+) TAAAAC/TCTAAC 1 -- us2k11Minor allele frequency- T:0.03NA 120
    rs113703981,2
    C--12691792(+) TTTTTT/-GTTTT 1 -- us2k1 trp31Minor allele frequency- -:0.00CSA 2
    rs1837095691,2
    --12691854(+) TGGCGC/TGATCT 1 -- us2k10--------
    rs1443677421,2
    --12692026(+) ACCTCA/GTGATC 1 -- us2k10--------
    rs1894898581,2
    --12692034(+) ATCCAC/TCCTCC 1 -- us2k10--------
    rs1929886861,2
    --12692069(+) ACAAGC/TGTGAG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ARHGAP44 (12692829 - 12894960 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for ARHGAP44:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2715665CNV Deletion23290073
    esv2715664CNV Deletion23290073
    esv2715666CNV Deletion23290073
    esv271684CNV Insertion20981092
    esv270747CNV Insertion20981092
    nsv833372CNV Loss17160897
    nsv112059CNV Loss16902084
    esv34095CNV Loss18971310

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ARHGAP44
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with ARHGAP44           About GenesLikeMe

    Genetic Association Database (GAD): ARHGAP44

    Export disorders for ARHGAP44 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ARHGAP44 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with ARHGAP44)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A CD317/tetherin-RICH2 complex plays a critical role in the organization of the subapical actin cytoskeleton in polarized epithelial cells. (PubMed id 19273615)1, 2, 3 Rollason R.... Banting G. (J. Cell Biol. 2009)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Rich, a rho GTPase-activating protein domain-containing protein involved in signaling by Cdc42 and Rac1. (PubMed id 11431473)1, 2 Richnau N. and Aspenstroem P. (J. Biol. Chem. 2001)
    4. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)1, 2 Ishikawa K.... Ohara O. (DNA Res. 1998)
    5. Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. (PubMed id 23648065)1 Low S.K....Nakamura Y. (Cancer Sci. 2013)
    6. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    7. The genetic architecture of economic and political preferences. (PubMed id 22566634)1 Benjamin D.J....Visscher P.M. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    8. Screening low-frequency SNPS from genome-wide association study reveals a new risk allele for progression to AIDS. (PubMed id 21107268)1 Le Clerc S....Zagury J.F. (J. Acquir. Immune Defic. Syndr. 2011)
    9. Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness. (PubMed id 17903302)4 Levy D....Mitchell G.F. (BMC Med. Genet. 2007)
    10. Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study. (PubMed id 17903301)4 Vasan R.S....Benjamin E.J. (BMC Med. Genet. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9912 HGNC: 29096 AceView: KIAA0672 Ensembl:ENSG00000006740 euGenes: HUgn9912
    ECgene: ARHGAP44 H-InvDB: ARHGAP44

    (According to HUGE)
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    HUGE: KIAA0672

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ARHGAP44 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ARHGAP44 gene:
    Search GeneIP for patents involving ARHGAP44

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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