Aliases for ARHGAP44 Gene
External Ids for ARHGAP44 Gene
Previous GeneCards Identifiers for ARHGAP44 Gene
GeneCards Summary for ARHGAP44 Gene
ARHGAP44 (Rho GTPase Activating Protein 44) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by Rho GTPases. GO annotations related to this gene include GTPase activator activity and phospholipid binding. An important paralog of this gene is SRGAP3.
UniProtKB/Swiss-Prot for ARHGAP44 Gene
GTPase-activating protein (GAP) that stimulates the GTPase activity of Rho-type GTPases. Thereby, controls Rho-type GTPases cycling between their active GTP-bound and inactive GDP-bound states. May act as a GAP for CDC42 and RAC1. Endosomal recycling protein which, in association with SHANK3, is involved in synaptic plasticity. Promotes GRIA1 exocytosis from recycling endosomes and spine morphological changes associated to long-term potentiation.