ARHGAP35 Gene
protein-coding GIFtS: 54
GCID: GC19P047422
|
|
Rho GTPase activating protein 35(Previous name: glucocorticoid receptor DNA binding factor 1 )
(Previous symbol: GRLF1)
| |
Aliases
for ARHGAP35 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Rho GTPase Activating Protein 351 2 | | Glucocorticoid Receptor DNA-Binding Factor 12 3 | | GRLF11 2 3 5 | | Glucocorticoid Receptor Repression Factor 12 3 | | GRF-11 2 3 | | Rho GAP P190A2 3 | | P190A1 2 5 | | P190-A2 | | Glucocorticoid Receptor DNA Binding Factor 11 2 | | Rho GTPase-Activating Protein 352 | | P190ARhoGAP1 | | GRF13 | | P190RhoGAP1 | | P190-A2 | | KIAA17221 3 | | |
Export aliases for ARHGAP35 gene to outside databases |
Summaries
for ARHGAP35 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ARHGAP35:
The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoidreceptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deducedfrom the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motifsuggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologousdown-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequencespecific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif.The level of expression is regulated by glucocorticoids. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: RHG35_HUMAN, Q9NRY4Function: Represses transcription of the glucocorticoid receptor by binding to the cis-acting regulatory sequence5'-GAGAAAAGAAACTGGAGAAACTC-3'. May participate in the regulation of retinal development and degeneration. Maytransduce signals from p21-ras to the nucleus, acting via the ras GTPase-activating protein (GAP). May also act as atumor suppressor
Gene Wiki entry for ARHGAP35 (GRLF1)
|
Genomic Views
for ARHGAP35 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for ARHGAP35
Other transcription factors
Search SABiosciences Chromatin IP Primers for ARHGAP35
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARHGAP35 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.3 Ensembl cytogenetic band: 19q13.32 HGNC cytogenetic band: 19q13.32ARHGAP35 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P047422: view genomic region
(about GC identifiers)
Start:
|
47,421,933 bp from pter |
End:
|
47,508,334 bp from pter |
Size:
|
86,402 bases |
Orientation:
|
plus strand |
|
Proteins
for ARHGAP35 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RHG35_HUMAN, Q9NRY4 (See
protein sequence)Recommended Name: Rho GTPase-activating protein 35 Size: 1499 amino acids; 170514 Da
Subunit: Interacts with RASA1
Subcellular location: Cytoplasm (By similarity). Nucleus (By similarity)
Sequence caution: Sequence=AAA58618.1; Type=Frameshift; Positions=389, 533, 540, 607, 614, 1167, 1241, 1292, 1334,1446; Sequence=AAF80386.1; Type=Frameshift; Positions=533, 540, 607, 614; Sequence=AAF80386.1; Type=Miscellaneousdiscrepancy; Note=Unlikely isoform. Aberrant splice sites;
3 PDB 3D structures from  and Proteopedia  for ARHGAP35:2K85 (3D)
3C5H (3D)
3FK2 (3D)
Secondary accessions: A7E2A4 Q14452 Q9C0E1Explore the universe of human proteins at neXtProt for ARHGAP35: NX_Q9NRY4
Post-translational modifications:
Phosphorylation of Tyr-1105 by PTK6 promotes the association with RASA1, inactivating RHOA while activating RAS1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NRY4
ARHGAP35 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_004482.4
ENSEMBL proteins: ENSP00000385720 Reactome Protein details: Q9NRY4
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
ARHGAP35 for ontologies About GeneDecksing
ARHGAP35 Antibody Products:
Assay Products for ARHGAP35: |
Protein
Domains /
Families
for ARHGAP35 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ARHGAP35 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9NRY4ProtoNet protein and cluster: Q9NRY4 2 Blocks protein families: IPB000198 RhoGAP domain IPB002713 FF domain
UniProtKB/Swiss-Prot: RHG35_HUMAN, Q9NRY4Similarity: Contains 4 FF domainsSimilarity: Contains 1 Rho-GAP domain |
Function
for ARHGAP35 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: RHG35_HUMAN, Q9NRY4Function: Represses transcription of the glucocorticoid receptor by binding to the cis-acting regulatory sequence5'-GAGAAAAGAAACTGGAGAAACTC-3'. May participate in the regulation of retinal development and degeneration. Maytransduce signals from p21-ras to the nucleus, acting via the ras GTPase-activating protein (GAP). May also act as atumor suppressor
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGAP35
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGAP35 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
ARHGAP35 for ontologies About GeneDecksing
Animal Models:
Mouse knock-outs for ARHGAP35: Grlf1tm2Jset Grlf1tm1Jset
7 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Grlf1):
ARHGAP35 for phenotypes About GeneDecksing
|
Pathways & Interactions
for ARHGAP35 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/14 super-pathways (see all 14) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cell adhesion_Integrin-mediated cell adhesion and migration | | | 2 | Axon guidance | | | 3 | Regulation of Actin Cytoskeleton | | | 4 | Sema4D in semaphorin signaling | | | 5 | Development_Endothelin-1/EDNRA transactivation of EGFR | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 EMD Millipore Pathways for ARHGAP35
1 
Cell Signaling Technology (CST) Pathway for ARHGAP35
3  GeneGo (Thomson Reuters) Pathways for ARHGAP35
4  BioSystems Pathways for ARHGAP35
5/8 
Reactome Pathways for ARHGAP35 (see all 8)
3 
Kegg Pathways (Kegg details for ARHGAP35):
ARHGAP35 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ARHGAP35
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/58 Interacting proteins for ARHGAP35 (Q9NRY43 ENSP000003857204) via UniProtKB, MINT, STRING, and/or I2D (see all 58)About this table
Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11): About this table
ARHGAP35 for ontologies About GeneDecksing
|
Drugs & Compounds
for ARHGAP35 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ARHGAP35 for compounds About GeneDecksing
 Browse Tocris compounds for ARHGAP35
1 Novoseek chemical compound relationship for ARHGAP35 gene About this table
Search CenterWatch for drugs/clinical trials and news about ARHGAP35 / RHG35
|
Transcripts
for ARHGAP35 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ARHGAP35 gene (2 alternative transcripts): NM_004491.4 NM_024342.1 Unigene Cluster for ARHGAP35: Rho GTPase activating protein 35 Hs.509447 [show with all ESTs]Unigene Representative Sequence: NM_0044911 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000404338(uc010ekv.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGAP35 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGAP35
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for ARHGAP35 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ARHGAP35 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARHGAP35 |
Additional cDNA sequence: AB051509.2 AF159851.1 AK097314.1 AK298356.1 AL831914.1 BC003514.1 BC065491.1 BC131565.1 BC150257.1 M73077.1 16 DOTS entries: DT.95093068 DT.114872 DT.95082732 DT.100030124 DT.99943524 DT.100813182 DT.100813179 DT.95093048 DT.95093069 DT.100813180 DT.102830952 DT.121504799 DT.95093082 DT.95312478 DT.121504741 DT.121504840 24/389 AceView cDNA sequences (see all 389): CA398198 CB131818 AW502056 BE041426 BE675998 BC003514 BQ425036 CA423691 AI432337 AB051509 BQ574330 BF477587 CA417886 CD299997 CF143487 BM843990 AI366708 BM973868 CF143345 AW873536 BI827118 BM545645 BX283112 BM843995
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for ARHGAP35 About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | ^ | 7a | · | 7b |
|---|
|
| SP1: | | | | | | | | | | | - | | - | | - | | | | - | | | | | | |
| SP2: | | | | | | | | | | | - | | - | | - | | | | - | | | | | | |
| SP3: | | | | | | | | | | | | | | | - | | | | - | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ARHGAP35
|
Expression
for ARHGAP35 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ARHGAP35 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TATTTGCTAC
About this image
See ARHGAP35 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ARHGAP35
SOURCE GeneReport for Unigene cluster: Hs.509447
SABiosciences Custom PCR Arrays for ARHGAP35
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ARHGAP35
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGAP35 |
Orthologs
for ARHGAP35 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ARHGAP35 gene from 5/18 species (see all 18) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ARHGAP351 |
Rho GTPase activating protein 35 |
73.1(n)
82.94(a) |
|
425730 XM_003643760.1 XP_003643808.1 |
lizard
(Anolis carolinensis) |
Reptilia |
ARHGAP356 |
-- |
92(a) |
1 ↔ 1 |
GL343566.1(191675-237789) |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
AL774029.22 |
-- |
75.2(n) |
|
AL774029.2 |
zebrafish
(Danio rerio) |
Actinopterygii |
BM184827.12 |
-- |
74.48(n) |
|
BM184827.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
RhoGAPp1901 |
CG32555-PA |
47.94(n)
36.57(a) |
|
32743 NM_133003.2 NP_573231.2 |
ENSEMBL Gene Tree for ARHGAP35 (if available)
TreeFam Gene Tree for ARHGAP35 (if available) |
Paralogs
for ARHGAP35 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ARHGAP35 gene
- ARHGAP52 SRGAP12 ARHGAP172 ARHGAP242 ARHGAP222 SRGAP32 ARHGAP442 SH3BP12
- ARHGAP42 SRGAP22 ARHGAP252
5 SIMAP similar genes for ARHGAP35 using alignment to 1 protein entry: RHG35_HUMAN:GRLF1 ARHGAP5 CHN1 ARHGAP12 ARHGAP9
ARHGAP35 for paralogs About GeneDecksing
|
Genomic Variants
for ARHGAP35 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ARHGAP35 (47421933 - 47508334 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ARHGAP35: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ARHGAP35 |
|
Disorders
/ Diseases
for ARHGAP35 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ARHGAP35 for disorders About GeneDecksing
OMIM gene information: 605277
OMIM disorders: --
6  diseases for ARHGAP35: About MalaCardscolon cancer breast carcinoma retinitis arthritis
melanoma carcinoma
2 Novoseek disease relationships for ARHGAP35 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| glioma |
14.4 |
3 |
12600941 (2), 11054565 (1) |
| tumors |
0 |
5 |
11054565 (3), 12600941 (1) |
Export disorders for ARHGAP35 gene to outside databases
|
Publications
for ARHGAP35 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ARHGAP35 gene, integrated from 9 sources (see all 80):
(articles sorted by number of sources associating them with ARHGAP35) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning and characterization of a factor that binds the human glucocorticoid receptor gene and represses its expression. (PubMed id 1894621)1, 2, 3, 9 LeClerc S.... Govindan M.V. (1991)
- p190-A, a human tumor suppressor gene, maps to the chromosomal region 19q13.3 that is reportedly deleted in some gliomas. (PubMed id 11054565)1, 2, 9 Tikoo A....Maruta H. (2000)
- Neutrophil functions and autoimmune arthritis in the absence of p190RhoGAP: generation and analysis of a novel null mutation in mice . (PubMed id 20675588)1, 3 NAcmeth T....MA^csai A. (2010)
- Breast tumor kinase phosphorylates p190RhoGAP to regulate rho and ras and promote breast carcinoma growth, migration, and invasion. (PubMed id 18829532)1, 2 Shen C.H....Chen R.H. (2008)
- Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (2005)
- Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
- Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2 Nagase T.... Ohara O. (2000)
- A FAK-p120RasGAP-p190RhoGAP complex regulates polarity in migrating cells. (PubMed id 19435801)1, 9 Tomar A....Schlaepfer D.D. (2009)
- Opposing roles of p190RhoGAP and Ect2 RhoGEF in regulating cytokinesis. (PubMed id 18642445)1, 9 Mikawa M....Parsons S.J. (2008)
- Activated G(alpha)13 impairs cell invasiveness through p190RhoGAP-mediated inhibition of RhoA activity. (PubMed id 18922893)1, 9 Bartolome R.A....Teixido J. (2008)
|
External Searches for ARHGAP35 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ARHGAP35 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ARHGAP35 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ARHGAP35 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ARHGAP35 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ARHGAP35 gene:
Search GeneIP for patents involving ARHGAP35
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ARHGAP35 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ARHGAP35 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ARHGAP35 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ARHGAP35 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ARHGAP35 | | OriGene 3'-UTR Clone for ARHGAP35 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGAP35 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGAP35 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ARHGAP35 | | OriGene Custom Protein Services for ARHGAP35 | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ARHGAP35 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ARHGAP35 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARHGAP35 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ARHGAP35 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARHGAP35 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARHGAP35 |
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| | Antibodies & Assays for ARHGAP35 (GRF-1) |
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 | | | ARHGAP35 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGAP35 |
|  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARHGAP35 |
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