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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ARHGAP33 Gene

protein-coding   GIFtS: 50
GCID: GC19P036266

Rho GTPase activating protein 33

(Previous name: sorting nexin 26 )
(Previous symbol: SNX26)
 Explore 3 diseases affiliated with
ARHGAP33 via our new
 Human Malady Compendium 
Biological research products
for ARHGAP33
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Rho GTPase Activating Protein 331 2     Tc10/CDC42 GTPase-Activating Protein2 3
SNX261 2 3     FLJ390191
TCGAP1 2 3     NOMA-GAP2
Sorting Nexin 261 2     Neurite Outgrowth Multiadaptor RhoGAP Protein2
Rho-Type GTPase-Activating Protein 332 3     Rho GTPase-Activating Protein 332
Sorting Nexin-262 3     

External Ids:    HGNC: 230851   Entrez Gene: 1157032   Ensembl: ENSG000000047777   OMIM: 6149025   UniProtKB: O145593   

Export aliases for ARHGAP33 gene to outside databases

Previous GC identifer: GC19P032771


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ARHGAP33:
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a
phosphoinositide binding domain, and are involved in intracellular trafficking. Alternative splice variants encoding
different isoforms have been identified in this gene. (provided by RefSeq, Feb 2010)

UniProtKB/Swiss-Prot: RHG33_HUMAN, O14559
Function: May be involved in several stages of intracellular trafficking. Could play an important role in the
regulation of glucose transport by insulin. May act as a downstream effector of RHOQ/TC10 in the regulation of
insulin-stimulated glucose transport (By similarity)

Gene Wiki entry for ARHGAP33 (SNX26)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011109.16  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for ARHGAP33
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidARHGAP33 promoter sequence
   Search SABiosciences Chromatin IP Primers for ARHGAP33

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARHGAP33


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.12   Ensembl cytogenetic band:  19q13.12   HGNC cytogenetic band: 19q13.13

ARHGAP33 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARHGAP33 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P036266:  view genomic region     (about GC identifiers)

Start:
36,265,434 bp from pter      End:
36,279,724 bp from pter
Size:
14,291 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RHG33_HUMAN, O14559 (See protein sequence)
Recommended Name: Rho GTPase-activating protein 33  
Size: 1287 amino acids; 137213 Da
Subunit: Specifically interacts with CDC42 and RHOQ/TC10 through its Rho-GAP domain (By similarity). Interacts with
NEK6
Sequence caution: Sequence=AAB81198.1; Type=Erroneous gene model prediction;
Secondary accessions: O14552 O14560 Q6ZSP6 Q96CP3 Q9NT23
Alternative splicing: 4 isoforms:  O14559-1   O14559-10   O14559-11   O14559-12   (Ref.2 (BAC86902) sequence differs from that shown due to several frameshifts)

Explore the universe of human proteins at neXtProt for ARHGAP33: NX_O14559

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O14559

  • ARHGAP33 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001166101.1  NP_443180.2  

    ENSEMBL proteins: 
     ENSP00000368227   ENSP00000465411   ENSP00000320038   ENSP00000467887   ENSP00000221905  
     ENSP00000468061   ENSP00000467844   ENSP00000466443   ENSP00000007510  

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    Uscn Proteins for ARHGAP33

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005737cytoplasm IEA--
    GO:0005886plasma membrane IEA--


    ARHGAP33 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ARHGAP33 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR011511 SH3_2
     IPR001683 Phox
     IPR008936 Rho_GTPase_activation_prot
     IPR001452 SH3_domain
     IPR000198 RhoGAP_dom

    Graphical View of Domain Structure for InterPro Entry O14559

    ProtoNet protein and cluster: O14559

    1 Blocks protein family: IPB000198 RhoGAP domain

    UniProtKB/Swiss-Prot: RHG33_HUMAN, O14559
    Similarity: Belongs to the PX domain-containing GAP family
    Similarity: Contains 1 PX (phox homology) domain
    Similarity: Contains 1 Rho-GAP domain
    Similarity: Contains 1 SH3 domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: RHG33_HUMAN, O14559
    Function: May be involved in several stages of intracellular trafficking. Could play an important role in the
    regulation of glucose transport by insulin. May act as a downstream effector of RHOQ/TC10 in the regulation of
    insulin-stimulated glucose transport (By similarity)

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    SwitchGear 3'UTR luciferase reporter plasmidARHGAP33 3' UTR sequence
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    Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005096GTPase activator activity ----
    GO:0005100Rho GTPase activator activity ----
    GO:0005515protein binding IPI16777849
    GO:0030675Rac GTPase activator activity IEA--
    GO:0035091phosphatidylinositol binding IEA--


    ARHGAP33 for ontologies           About GeneDecksing


    Animal Models:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Arhgap33):
     nervous system 

    ARHGAP33 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Insulin Signaling
    Insulin Signaling1.00


    1 BioSystems Pathway for ARHGAP33 
        Insulin Signaling


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ARHGAP33

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/39 Interacting proteins for ARHGAP33 (O145591, 3 ENSP000003200384) via UniProtKB, MINT, STRING, and/or I2D (see all 39)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FYNP062411, 3, ENSP000003576564EBI-1210010,EBI-2561531 I2D: score=4 STRING: ENSP00000357656
    RAC1P630003, ENSP000003484614I2D: score=3 STRING: ENSP00000348461
    CDC42P609533I2D: score=1 
    RHOJQ9H4E53I2D: score=1 
    YWHAEP622583I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction IEA--
    GO:0015031protein transport IEA--
    GO:0032321positive regulation of Rho GTPase activity ----
    GO:0032855positive regulation of Rac GTPase activity ----


    ARHGAP33 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ARHGAP33
    Search CenterWatch for drugs/clinical trials and news about ARHGAP33 / RHG33 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ARHGAP33 gene (2 alternative transcripts): 
    NM_001172630.1  NM_052948.3  

    Unigene Cluster for ARHGAP33:

    Rho GTPase activating protein 33
    Hs.515364  [show with all ESTs]
    Unigene Representative Sequence: NM_001172630
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000589133 ENST00000378944(uc002obt.2) ENST00000590893 ENST00000314737(uc002obs.2)
    ENST00000592958 ENST00000221905(uc010eek.2) ENST00000587433 ENST00000588248
    ENST00000591438 ENST00000586918 ENST00000587447 ENST00000593034 ENST00000587984
    ENST00000007510(uc002obr.2 uc002obv.1)

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    Additional cDNA sequence: 

    AK096338.1 AK127255.1 AL137579.1 AY044864.1 BC014084.2 BC128586.1 

    8 DOTS entries:

    DT.436066  DT.406020  DT.100751306  DT.75190586  DT.121409149  DT.40109448  DT.406018  DT.91888560 

    24/40 AceView cDNA sequences (see all 40):

    CD557424 CR625873 BC014084 Z38468 AY044864 AL137579 AK127255 NM_052948 
    AK096338 AA299345 BI524193 AI823348 AL536431 BX431652 BG913058 BX281283 
    BX431046 Z42222 AI823347 BI523815 AI369841 BG912541 BI915639 AW166303 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for ARHGAP33 (see all 9)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b ^ 15 ^ 16 ^ 17a · 17b ^ 18a · 18b · 18c ^ 19 ^ 20 ^
    SP1:                                                                                                                                                            
    SP2:                                -                                                                                                                           
    SP3:                                                                                                                                -                           
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 21 ^ 22 ^ 23
    SP1:                  
    SP2:                  
    SP3:                  
    SP4:                  
    SP5:                  


    ECgene alternative splicing isoforms for ARHGAP33

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ARHGAP33 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CCCCACTAAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See ARHGAP33 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ARHGAP33

    SOURCE GeneReport for Unigene cluster: Hs.515364
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ARHGAP33 gene from 3/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    --
    70(a)
    20(a)
    1 ↔ many
    1 ↔ many
    GL343276.1(1400934-1415441)
    GL343276.1(1378296-1399273)
    fruit fly
    (Drosophila melanogaster)
    Insecta CdGAPr6
    CdGAPr
    15(a)
    1 → many
    2L(19774873-19791882)
    worm
    (Caenorhabditis elegans)
    Secernentea rga-56
    rrc-16
    GTPase-activating protein rrc-1
    4(a)
    12(a)
    possible ortholog
    1 ↔ many
    IV(13827861-13844953)
    X(9823702-9831191)


    ENSEMBL Gene Tree for ARHGAP33 (if available)
    TreeFam Gene Tree for ARHGAP33 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ARHGAP33 gene
    ARHGAP302  RALBP12  ARHGAP322  ARHGAP312  
    11 SIMAP similar genes for ARHGAP33 using alignment to 5 protein entries:     RHG33_HUMAN (see all proteins):
    SNX26    ARHGAP31    RICS    ARHGAP32    DKFZp451F1115    ARHGAP12
    CHN1    FAM13A    ARHGAP9    ARHGAP21    ARHGAP23

    ARHGAP33 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for ARHGAP33
    PGOHUM00000256835


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/312 NCBI SNPs in ARHGAP33 are shown (see all 312    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1404453231,2
    C,probable-non-pathogenic36275163(+) GCTCAC/TCCATG 4 T I mis11Minor allele frequency- T:0.00NA 4548
    rs1502116451,2
    --36264426(+) AGAAGC/GAATAT 2 -- us2k10--------
    rs39334211,2
    C,F,A,H,--36264642(+) TGACTG/ACAACC 2 -- us2k13Minor allele frequency- A:0.33NA WA 6
    rs666385131,2
    C,--36264651(+) CCTCCA/GCCTCC 2 -- us2k12Minor allele frequency- G:0.25NA 4
    rs8074821,2
    C,F,A,--36264722(+) ACCACG/ACCTGG 2 -- us2k17Minor allele frequency- A:0.46NA WA CSA 13
    rs8074831,2
    C,F,A,--36264860(+) CACTGC/TCCCCA 2 -- us2k15Minor allele frequency- T:0.44NA WA CSA 9
    rs8074841,2
    C,F,A,H,--36264986(+) CCATTG/CTCTTG 2 -- us2k17Minor allele frequency- C:0.48NA WA CSA 133
    rs1814041361,2
    --36265064(+) TTAGTA/GGAGAC 2 -- us2k10--------
    rs1862703121,2
    --36265119(+) CAAGTA/GATCTG 2 -- us2k10--------
    rs116719851,2
    C,F,H,--36265132(+) CGCCTC/TGGCCT 2 -- us2k11Minor allele frequency- T:0.50NA 4

    HapMap Linkage Disequilibrium report for ARHGAP33 (36265434 - 36279724 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for ARHGAP33: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ARHGAP33 for disorders           About GeneDecksing

    OMIM gene information: 614902    OMIM disorders: --

    3 diseases for ARHGAP33:    About MalaCards
    noma    endometriosis    cholesterol

    Human Genome Epidemiology (HuGE) Navigator: ARHGAP33 (0 documents)

    Export disorders for ARHGAP33 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ARHGAP33 gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with ARHGAP33)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
    4. Human RhoGAP domain-containing proteins: structure, function and evolutionary relationships. (PubMed id 12297274)1, 3 Peck J....Burbelo P.D. (2002)
    5. Sorting out the cellular functions of sorting nexins. (PubMed id 12461558)1, 3 Worby C.A. and Dixon J.E. (2002)
    6. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    7. A human MAP kinase interactome. (PubMed id 20936779)1 Bandyopadhyay S....Ideker T. (2010)
    8. Characterization of hNek6 interactome reveals an impo rtant role for its short N-terminal domain and colocalization with proteins at the centrosome. (PubMed id 20873783)2 Vaz Meirelles G....Kobarg J. (2010)
    9. Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. (PubMed id 18660489)1 Lu Y....Boer J.M. (2008)
    10. The neurite outgrowth multiadaptor RhoGAP, NOMA-GAP, regulates neurite extension through SHP2 and Cdc42. (PubMed id 17664338)1 Rosario M....Birchmeier W. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 115703 HGNC: 23085 AceView: SNX26 Ensembl:ENSG00000004777 euGenes: HUgn115703
    ECgene: ARHGAP33 H-InvDB: ARHGAP33

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ARHGAP33 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ARHGAP33 gene:
    Search GeneIP for patents involving ARHGAP33

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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