Aliases for ARHGAP33 Gene
External Ids for ARHGAP33 Gene
Previous HGNC Symbols for ARHGAP33 Gene
Previous GeneCards Identifiers for ARHGAP33 Gene
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Alternative splice variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]
GeneCards Summary for ARHGAP33 Gene
ARHGAP33 (Rho GTPase Activating Protein 33) is a Protein Coding gene. Diseases associated with ARHGAP33 include Noma. Among its related pathways are Signaling by GPCR and Insulin Signaling. GO annotations related to this gene include GTPase activator activity and phosphatidylinositol binding. An important paralog of this gene is ARHGAP32.
UniProtKB/Swiss-Prot for ARHGAP33 Gene
May be involved in several stages of intracellular trafficking. Could play an important role in the regulation of glucose transport by insulin. May act as a downstream effector of RHOQ/TC10 in the regulation of insulin-stimulated glucose transport (By similarity).