Aliases for ARHGAP29 Gene
External Ids for ARHGAP29 Gene
Previous GeneCards Identifiers for ARHGAP29 Gene
GeneCards Summary for ARHGAP29 Gene
ARHGAP29 (Rho GTPase Activating Protein 29) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by Rho GTPases. GO annotations related to this gene include GTPase activator activity and PDZ domain binding. An important paralog of this gene is HMHA1.
UniProtKB/Swiss-Prot for ARHGAP29 Gene
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42. May act as a specific effector of RAP2A to regulate Rho. In concert with RASIP1, suppresses RhoA signaling and dampens ROCK and MYH9 activities in endothelial cells and plays an essential role in blood vessel tubulogenesis.