Aliases for ARHGAP25 Gene
External Ids for ARHGAP25 Gene
ARHGAPs, such as ARHGAP25, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]).[supplied by OMIM, Mar 2008]
GeneCards Summary for ARHGAP25 Gene
ARHGAP25 (Rho GTPase Activating Protein 25) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Rho GTPase cycle. GO annotations related to this gene include phospholipid binding and GTPase activator activity. An important paralog of this gene is SRGAP3.
UniProtKB/Swiss-Prot for ARHGAP25 Gene
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.