Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ARHGAP23 Gene

protein-coding   GIFtS: 45
GCID: GC17P036584

Rho GTPase activating protein 23

 Explore 1 disease affiliated with
ARHGAP23 via our new
 Human Malady Compendium 
Biological research products
for ARHGAP23
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Rho GTPase Activating Protein 231 2
KIAA15011 3 5
Rho-Type GTPase-Activating Protein 232 3
Rho GTPase-Activating Protein 232

External Ids:    HGNC: 292931   Entrez Gene: 576362   Ensembl: ENSG000002254857   OMIM: 6105905   UniProtKB: Q9P2273   

Export aliases for ARHGAP23 gene to outside databases

Previous GC identifers: GC17P036984 GC17P033825 GC17P032409


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ARHGAP23:
The RHO (see ARHA; MIM 165390) family of small GTPases are involved in signal transduction through transmembrane
receptors, and they are inactive in the GDP-bound form and active in the GTP-bound form. GTPase-activating proteins,
such as ARHGAP23, inactivate RHO family proteins by stimulating their hydrolysis of GTP (Katoh and Katoh, 2004 (PubMed
15254754)).(supplied by OMIM, Mar 2008)

UniProtKB/Swiss-Prot: RHG23_HUMAN, Q9P227
Function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010783.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ARHGAP23 gene promoter:
         c-Fos   AP-1   Fra-1   FosB   GATA-1   Arnt   PPAR-alpha   ARP-1   c-Jun   ZIC2/Zic2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for ARHGAP23

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARHGAP23


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q12   Ensembl cytogenetic band:  17q12   HGNC cytogenetic band: 17q12

ARHGAP23 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARHGAP23 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P036584:  view genomic region     (about GC identifiers)

Start:
36,584,662 bp from pter      End:
36,668,628 bp from pter
Size:
83,967 bases      Orientation:
plus strand

1 alternative location:
Chr17+,PATCHES 36,613,644-36,668,628     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RHG23_HUMAN, Q9P227 (See protein sequence)
Recommended Name: Rho GTPase-activating protein 23  
Size: 1491 amino acids; 162192 Da
Alternative splicing: 2 isoforms:  Q9P227-1   Q9P227-2   (No experimental confirmation available. Gene prediction based on EST data)

Explore the universe of human proteins at neXtProt for ARHGAP23: NX_Q9P227

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9P227

  • ARHGAP23 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001186346.1  
    ENSEMBL proteins: 
     ENSP00000393539   ENSP00000394153   ENSP00000447644   ENSP00000446960   ENSP00000463603  
     ENSP00000468573   ENSP00000447601   ENSP00000462066   ENSP00000407333  
    Reactome Protein details: Q9P227
    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom Protein Services for ARHGAP23 
    GenScript Custom Purified and Recombinant Proteins Services for ARHGAP23
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for ARHGAP23

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular IEA--


    ARHGAP23 for ontologies           About GeneDecksing



    ARHGAP23 Antibody Products: 
    EMD Millipore Mono- and Polyclonal Antibodies for the study of ARHGAP23
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ARHGAP23 
    GenScript Custom Superior Antibodies Services for ARHGAP23
    Novus Biologicals ARHGAP23 Antibody
    Search for Antibodies for ARHGAP23 at Abcam  
    Uscn Antibodies for ARHGAP23
    Search ThermoFisher Antibodies for ARHGAP23

    Assay Products for ARHGAP23: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ARHGAP23
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for ARHGAP23


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ARHGAP23 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR001478 PDZ
     IPR008936 Rho_GTPase_activation_prot
     IPR001849 Pleckstrin_homology
     IPR011993 PH_like_dom
     IPR000198 RhoGAP_dom

    Graphical View of Domain Structure for InterPro Entry Q9P227

    ProtoNet protein and cluster: Q9P227

    2 Blocks protein families:
    IPB000198 RhoGAP domain
    IPB001849 Pleckstrin-like


    UniProtKB/Swiss-Prot: RHG23_HUMAN, Q9P227
    Similarity: Contains 1 PDZ (DHR) domain
    Similarity: Contains 1 PH domain
    Similarity: Contains 1 Rho-GAP domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: RHG23_HUMAN, Q9P227
    Function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By similarity)

    miRNA
    Products:
        
    OriGene 3'-UTR Clone: ARHGAP23
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ARHGAP23
    8/43 QIAGEN miScript miRNA Assays for microRNAs that regulate ARHGAP23 (see all 43):
    hsa-miR-1197 hsa-miR-128 hsa-miR-200a hsa-miR-374a hsa-miR-138-2* hsa-miR-500a hsa-miR-141 hsa-miR-3658
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ARHGAP23 (see all 4)
    OriGene shRNA RFP: ARHGAP23
    OriGene siRNA: ARHGAP23
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ARHGAP23

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ARHGAP23

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGAP23
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGAP23
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: ARHGAP23 (NM_001199417)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ARHGAP23
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ARHGAP23 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ARHGAP23
    Search LifeMap BioReagents cell lines for ARHGAP23

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGAP23

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005096GTPase activator activity IEA--
    GO:0005543phospholipid binding IEA--


    ARHGAP23 for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Cell death signalling via NRAGE, NRIF and NADE
    Signaling by Rho GTPases0.25
    Rho GTPase cycle0.25
    2Signaling by GPCR
    Signal Transduction0.56

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    3        Reactome Pathways for ARHGAP23
        Signaling by Rho GTPases
    Signal Transduction
    Rho GTPase cycle



    ARHGAP23 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ARHGAP23

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for ARHGAP23 (Q9P2273 ENSP000004073334) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MEPCEQ7L2J03, ENSP000003085464I2D: score=1 STRING: ENSP00000308546
    RPAP1Q9BWH63, ENSP000003061234I2D: score=1 STRING: ENSP00000306123
    HNRNPA1P096513, ENSP000003418264I2D: score=1 STRING: ENSP00000341826
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction IEA--


    ARHGAP23 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ARHGAP23
    Search CenterWatch for drugs/clinical trials and news about ARHGAP23 / RHG23 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ARHGAP23 gene (2 alternative transcripts): 
    NM_020876.1  NM_001199417.1  

    Unigene Cluster for ARHGAP23:

    Rho GTPase activating protein 23
    Hs.374446  [show with all ESTs]
    Unigene Representative Sequence: NM_001199417
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000431231(uc021twd.1 uc002hqc.3) ENST00000437668(uc021twe.1)
    ENST00000582409 ENST00000549246 ENST00000548333 ENST00000581782 ENST00000578665
    ENST00000548703 ENST00000581023 ENST00000547158 ENST00000583703 ENST00000443378


    miRNA
    Products:
         
    OriGene 3'-UTR Clone: ARHGAP23
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ARHGAP23
    8/43 QIAGEN miScript miRNA Assays for microRNAs that regulate ARHGAP23 (see all 43):
    hsa-miR-1197 hsa-miR-128 hsa-miR-200a hsa-miR-374a hsa-miR-138-2* hsa-miR-500a hsa-miR-141 hsa-miR-3658
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ARHGAP23 (see all 4)
    OriGene shRNA RFP: ARHGAP23
    OriGene siRNA: ARHGAP23
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ARHGAP23
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGAP23
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGAP23
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: ARHGAP23 (NM_001199417)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ARHGAP23
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ARHGAP23 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ARHGAP23
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ARHGAP23
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARHGAP23
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARHGAP23

    Additional cDNA sequence: BC039190.1 

    10 DOTS entries:

    DT.92429796  DT.454892  DT.92429795  DT.92429793  DT.92429798  DT.92029612  DT.97786214  DT.120923277 
    DT.91721354  DT.91815448 

    24/184 AceView cDNA sequences (see all 184):

    N98984 AI436239 R56748 AA374460 CA488127 AW297528 BQ027932 AA351347 
    AI123323 AI971411 AA478252 AB076968 AI924604 AB040934 AA478253 F10078 
    BM548592 CA943274 AI336895 BU180944 AI924149 CN484023 BM804823 BF514614 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ARHGAP23 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See ARHGAP23 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ARHGAP23

    SOURCE GeneReport for Unigene cluster: Hs.374446

    UniProtKB/Swiss-Prot: RHG23_HUMAN, Q9P227
    Tissue specificity: Expressed in placenta, prostate, hippocampus and brain medulla. Also expressed in brain tumor,
    salivary gland tumor, head and neck tumor

        SABiosciences Custom PCR Arrays for ARHGAP23
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ARHGAP23
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ARHGAP23
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARHGAP23
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARHGAP23
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGAP23

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ARHGAP23 gene from 4/19 species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    lizard
    (Anolis carolinensis)
    Reptilia ARHGAP236
    --
    64(a)
    1 ↔ 1
    6(73716023-73762282)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1000062331 rho GTPase-activating protein 23-like 58.76(n)
    57.36(a)
      100006233  XM_003198148.1  XP_003198196.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RhoGAP19D6
    RhoGAP19D
    12(a)
    1 → many
    X(20340982-20381721)
    worm
    (Caenorhabditis elegans)
    Secernentea rga-56
    pac-16
    GTPase-activating protein pac-1
    5(a)
    14(a)
    possible ortholog
    1 ↔ many
    IV(13827861-13844953)
    III(8493801-8518803)


    ENSEMBL Gene Tree for ARHGAP23 (if available)
    TreeFam Gene Tree for ARHGAP23 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ARHGAP23 gene
    HMHA12  ARHGAP212  ARHGAP272  CHN22  ARHGAP102  ARHGAP92  ARHGAP292  ARHGAP262  
    CHN12  ARHGAP152  ARHGAP122  OPHN12  GMIP2  ARHGAP422  
    18/38 SIMAP similar genes for ARHGAP23 using alignment to 8 protein entries:     RHG23_HUMAN (see all proteins) (see all similar genes):
    ARHGAP21    CYTIP    SHANK3    ARHGAP29    MAGI1    MAST4
    SLC9A3R1    ARHGAP44    DKFZp434B034    MAGI2    OPHN1    SHANK2
    ARHGEF12    MAST2    MAST3    PDZD2    ARHGAP24    SCRIB

    ARHGAP23 for paralogs           About GeneDecksing


    3 Pseudogenes.org Pseudogenes for ARHGAP23
    PGOHUM00000259060 PGOHUM00000259120 PGOHUM00000259124


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1334 NCBI SNPs in ARHGAP23 are shown (see all 1334    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs80768991,2
    C,F,A,--36582793(+) ACTCCG/ATCTCA 1 -- us2k15Minor allele frequency- A:0.33NA WA CSA 9
    rs1473450371,2
    --36583003(+) TACATA/TAAATA 1 -- us2k10--------
    rs1397813991,2
    --36583087(+) CTGGGG/TCACCC 1 -- us2k10--------
    rs1911582341,2
    --36583317(+) AACTGA/TAAAAG 1 -- us2k10--------
    rs782926681,2
    F,--36583320(+) TGAAAA/CAGTCA 1 -- us2k11Minor allele frequency- C:0.18WA 118
    rs1123194801,2
    --36583384(+) TTAGAT/CAGTAG 1 -- us2k12Minor allele frequency- C:0.07CSA WA 120
    rs1414480821,2
    C,--36583395(+) AAGAA-/TTTT  
            
    TTTTC
    1 -- us2k10--------
    rs1453140581,2
    --36583571(+) GTGGGC/TGGTGT 1 -- us2k10--------
    rs1162537981,2
    F,--36583604(+) TACCTG/CGGGAG 1 -- us2k11Minor allele frequency- C:0.03WA 118
    rs114083021,2
    C--36583710(+) AAAAA-/AGGAAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ARHGAP23 (36584662 - 36668628 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 7 variations for ARHGAP23
         7 CNVs: 88452 88453 67187 4034 30828 2224 77589

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ARHGAP23
    DNA2.0 Custom Variant and Variant Library Synthesis for ARHGAP23

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ARHGAP23 for disorders           About GeneDecksing

    OMIM gene information: 610590    OMIM disorders: --

    1 disease for ARHGAP23:    About MalaCards
    prostatitis


    Export disorders for ARHGAP23 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ARHGAP23 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with ARHGAP23)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of human ARHGAP23 gene in silico. (PubMed id 15254754)1, 2, 3, 9 Katoh M. and Katoh M. (2004)
    2. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)1, 2, 3 Nagase T.... Ohara O. (2000)
    3. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)1, 2 Zody M.C.... Nusbaum C. (2006)
    4. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    5. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    6. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
    7. Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. (PubMed id 17643375)1 Jeronimo C.... Coulombe B. (2007)
    8. Genomic annotation of 15,809 ESTs identified from pooled early gestation human eyes. (PubMed id 16368877)1 Choy K.W....Pang C.P. (2006)
    9. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57636 HGNC: 29293 AceView: ARHGAP23.1 Ensembl:ENSG00000225485 euGenes: HUgn57636
    ECgene: ARHGAP23 H-InvDB: ARHGAP23

    (According to HUGE)
    About This Section
    HUGE: KIAA1501

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ARHGAP23 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ARHGAP23 gene:
    Search GeneIP for patents involving ARHGAP23

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     Browse Small Molecules at EMD Millipore
     Browse Kits and Assays available from EMD Millipore
     EMD Millipore Mono- and Polyclonal Antibodies for the study of ARHGAP23
     Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
     Browse for Gene Knock-down Tools from EMD Millipore
     Browse Purified and Recombinant Proteins at EMD Millipore
     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for ARHGAP23  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ARHGAP23   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ARHGAP23  
     Browse OriGene Protein Over-expression Lysates   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for ARHGAP23   OriGene 3'-UTR Clone for ARHGAP23  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGAP23   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARHGAP23  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ARHGAP23   OriGene Custom Protein Services for ARHGAP23  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ARHGAP23
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ARHGAP23
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARHGAP23
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ARHGAP23
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARHGAP23
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARHGAP23
     GenScript Custom Purified and Recombinant Proteins Services for ARHGAP23 GenScript cDNA clones with any tag delivered in your preferred vector for ARHGAP23
     GenScript Custom Assay Services for ARHGAP23 GenScript Custom Superior Antibodies Services for ARHGAP23
     GenScript Custom overexpressing Cell Line Services for ARHGAP23 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in ARHGAP23 promoter
     Search Chromatin IP Primers for ARHGAP23
     RT2 qPCR Primer Assay in human, mouse / rat ARHGAP23
     Search GNC Networks for ARHGAP23
     SABiosciences Custom PCR Arrays for ARHGAP23
     Search Tocris compounds for ARHGAP23
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ARHGAP23 antibodies
     Search for Antibodies for ARHGAP23 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for ARHGAP23
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     ARHGAP23 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for ARHGAP23
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGAP23
     Browse SwitchGear 3'UTR luciferase reporter plasmids for ARHGAP23
     Browse SwitchGear Promoter luciferase reporter plasmids for ARHGAP23
     Search ThermoFisher Antibodies for ARHGAP23
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ARHGAP23
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ARHGAP23 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4