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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ARHGAP20 Gene

protein-coding   GIFtS: 58
GCID: GC11M110447

Rho GTPase Activating Protein 20

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Rho GTPase Activating Protein 201 2     Rho GTPase Activating Protein 20 Variant 22
Rho-Type GTPase-Activating Protein 202 3     Rho GTPase-Activating Protein 202
RARHOGAP2     KIAA13913
RA And RhoGAP Domain Containing Protein2     

External Ids:    HGNC: 183571   Entrez Gene: 575692   Ensembl: ENSG000001377277   OMIM: 6095685   UniProtKB: Q9P2F63   

Export aliases for ARHGAP20 gene to outside databases

Previous GC identifers: GC11M109985 GC11M109952 GC11M106372


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ARHGAP20 Gene: 
ARHGAP20 (Rho GTPase activating protein 20) is a protein-coding gene. Diseases associated with ARHGAP20 include b-cell chronic lymphocytic leukemia, and sinusitis, and among its related super-pathways are Signaling by Rho GTPases and Signaling by GPCR. GO annotations related to this gene include phospholipid binding and GTPase activator activity. An important paralog of this gene is TAGAP.

UniProtKB/Swiss-Prot: RHG20_HUMAN, Q9P2F6
Function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NT_033899.8  NC_018922.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ARHGAP20 gene promoter:
         NF-1   RP58   FOXD3   Nkx2-5   Meis-1b   C/EBPalpha   Egr-2   AREB6   Meis-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidARHGAP20 promoter sequence
   Search SABiosciences Chromatin IP Primers for ARHGAP20

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARHGAP20


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q23.1   Ensembl cytogenetic band:  11q23.1   HGNC cytogenetic band: 11q23.2

ARHGAP20 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARHGAP20 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M110447:  view genomic region     (about GC identifiers)

Start:
110,447,766 bp from pter      End:
110,583,912 bp from pter
Size:
136,147 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RHG20_HUMAN, Q9P2F6 (See protein sequence)
Recommended Name: Rho GTPase-activating protein 20  
Size: 1191 amino acids; 132608 Da
Developmental stage: Low expression is found in fetal liver
Caution: The translocation involving this gene was originally published as t(X;11)(q13;23) (PubMed:15543602), but
BRWD3 is localized to Xq21 and not to Xq13
Sequence caution: Sequence=AAH39340.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=AAH39340.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact; Sequence=BAA92629.1;
Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=BAF84979.1; Type=Erroneous
initiation; Note=Translation N-terminally shortened; Sequence=BAF84979.1; Type=Miscellaneous discrepancy;
Note=Probable cloning artifact;
1 PDB 3D structure from and Proteopedia for ARHGAP20:
3MSX (3D)    
Secondary accessions: A8K8C5 B0YIW7 B0YIW8 Q6RJU1 Q6RJU2 Q6RJU3 Q6RJU5 Q8IXS1
Alternative splicing: 4 isoforms:  Q9P2F6-1   Q9P2F6-2   Q9P2F6-3   Q9P2F6-4   

Explore the universe of human proteins at neXtProt for ARHGAP20: NX_Q9P2F6

Explore proteomics data for ARHGAP20 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9P2F6

  • ARHGAP20 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ARHGAP20 Protein Expression
    REFSEQ proteins (5 alternative transcripts): 
    NP_001245344.1  NP_001245345.1  NP_001245346.1  NP_001245347.1  NP_065860.2  

    ENSEMBL proteins: 
     ENSP00000260283   ENSP00000437905   ENSP00000432076   ENSP00000436319   ENSP00000436522  
     ENSP00000431399   ENSP00000349660  
    Reactome Protein details: Q9P2F6
    Human Recombinant Protein Products for ARHGAP20: 
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    Novus Biologicals ARHGAP20 Lysates
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ARHGAP20 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005829cytosol TAS--

    ARHGAP20 for ontologies           About GeneDecksing



    ARHGAP20 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ARHGAP: Rho GTPase activating proteins

    5 InterPro protein domains:
     IPR008936 Rho_GTPase_activation_prot
     IPR001849 Pleckstrin_homology
     IPR011993 PH_like_dom
     IPR000198 RhoGAP_dom
     IPR000159 Ras-assoc

    Graphical View of Domain Structure for InterPro Entry Q9P2F6

    ProtoNet protein and cluster: Q9P2F6

    3 Blocks protein domains:
    IPB000159 RA domain
    IPB000198 RhoGAP domain
    IPB001849 Pleckstrin-like


    UniProtKB/Swiss-Prot: RHG20_HUMAN, Q9P2F6
    Similarity: Contains 1 PH domain
    Similarity: Contains 1 Ras-associating domain
    Similarity: Contains 1 Rho-GAP domain


    ARHGAP20 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RHG20_HUMAN, Q9P2F6
    Function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By
    similarity)

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005096GTPase activator activity IEA--
    GO:0005515protein binding ----
    GO:0005543phospholipid binding IEA--
         
    ARHGAP20 for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for ARHGAP20:
     Abundance of large cells with   Decreased viability of wild-ty  Increased G1 DNA content  Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ARHGAP20 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ARHGAP20 
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    SwitchGear 3'UTR luciferase reporter plasmidARHGAP20 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ARHGAP20 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Rho GTPase cycle
    Rho GTPase cycle1.00
    Signaling by Rho GTPases1.00
    2Signaling by GPCR
    Signal Transduction0.55

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3        Reactome Pathways for ARHGAP20
        Signaling by Rho GTPases
    Signal Transduction
    Rho GTPase cycle



    ARHGAP20 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ARHGAP20

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5 Interacting proteins for ARHGAP20 (Q9P2F63 ENSP000002602834) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TERF2Q155543, ENSP000002549424I2D: score=1 STRING: ENSP00000254942
    BMPR1BO002383I2D: score=1 
    RHOAENSP000004001754STRING: ENSP00000400175
    GRB2ENSP000003390074STRING: ENSP00000339007
    SIRT5ENSP000003685524STRING: ENSP00000368552
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction ----
    GO:0007264small GTPase mediated signal transduction TAS--
    GO:0051056regulation of small GTPase mediated signal transduction TAS--

    ARHGAP20 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ARHGAP20 (RHG20)

    Search CenterWatch for drugs/clinical trials and news about ARHGAP20 / RHG20

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ARHGAP20 gene (5 alternative transcripts): 
    NM_001258415.1  NM_001258416.1  NM_001258417.1  NM_001258418.1  NM_020809.3  

    Unigene Cluster for ARHGAP20:

    Rho GTPase activating protein 20
    Hs.6136  [show with all ESTs]
    Unigene Representative Sequence: NM_001258415
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000260283(uc001pkz.1 uc009yyb.1) ENST00000529591(uc001plb.2)
    ENST00000524756(uc001pky.1) ENST00000528829 ENST00000533353(uc001pla.1)
    ENST00000527598 ENST00000357139
    miRNA
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    8/87 QIAGEN miScript miRNA Assays for microRNAs that regulate ARHGAP20 (see all 87):
    hsa-miR-607 hsa-miR-300 hsa-miR-15a hsa-miR-199a-3p hsa-miR-485-3p hsa-miR-374a hsa-miR-10b* hsa-miR-556-3p
    SwitchGear 3'UTR luciferase reporter plasmidARHGAP20 3' UTR sequence
    Inhib. RNA
    Products:
         
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    Additional mRNA sequence: 

    AB037812.1 AK292290.1 AK307602.1 AY496263.1 AY496264.1 AY496265.1 AY496266.1 AY496267.1 
    BC039340.1 

    5 DOTS entries:

    DT.312981  DT.102823760  DT.95139488  DT.102823761  DT.102823762 

    24/46 AceView cDNA sequences (see all 46):

    NM_020809 AY496265 BC039340 AY496263 AB037812 BX095222 BX508298 AY496267 
    Z39921 AY496264 AY496266 BI464112 Z43854 AI222036 AI698688 AI936560 
    AW205620 BQ003257 AA846778 AI300211 AW892501 CF552743 AA884003 BX119603 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ARHGAP20 (see all 6)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20a · 20b ^ 21
    SP1:        -     -     -                                                                       -                                       
    SP2:                    -     -                                                                 -                                       
    SP3:        -     -     -     -                                                                 -                                       
    SP4:              -     -     -                                                                 -                                       
    SP5:                          -                                                                 -                                       


    ECgene alternative splicing isoforms for ARHGAP20

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ARHGAP20 expression in normal human tissues (normalized intensities)      ARHGAP20 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGTCTGTTA
    ARHGAP20 Expression
    About this image


    ARHGAP20 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/1 selected tissues (see all 1) fully expand
     
     Testis (Reproductive System)
             Testicular Interstitial Cells Testis Interstitium

    See ARHGAP20 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ARHGAP20

    SOURCE GeneReport for Unigene cluster: Hs.6136

    UniProtKB/Swiss-Prot: RHG20_HUMAN, Q9P2F6
    Tissue specificity: Expressed predominantly in the brain. Lower expression is found in lymph nodes

        SABiosciences Custom PCR Arrays for ARHGAP20
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGAP20

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ARHGAP20 gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Arhgap201 , 5 Rho GTPase activating protein 201, 5 82.27(n)1
    80.1(a)1
      9 (28.62 cM)5
    2448671  NM_175535.31  NP_780744.21 
     517653375 
    chicken
    (Gallus gallus)
    Aves ARHGAP201 Rho GTPase activating protein 20 64.29(n)
    58(a)
      418962  XM_417154.3  XP_417154.2 
    lizard
    (Anolis carolinensis)
    Reptilia --
    ARHGAP206
    Rho GTPase activating protein 20
    57(a)
    47(a)
    possible ortholog
    1 ↔ 1
    GL343465.1(559025-595381)
    3(186529916-186641525)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.44092 Transcribed sequence with weak similarity to protein more 73.12(n)    AL850639.2 
    zebrafish
    (Danio rerio)
    Actinopterygii arhgap201 Rho GTPase activating protein 20 56.94(n)
    49.74(a)
      796434  XM_001336727.4  XP_001336763.2 
    worm
    (Caenorhabditis elegans)
    Secernentea rga-26
    Protein RGA-2
    18(a)
    1 → many
    I(11979440-11985655)


    ENSEMBL Gene Tree for ARHGAP20 (if available)
    TreeFam Gene Tree for ARHGAP20 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ARHGAP20 gene
    TAGAP2  
    1 SIMAP similar gene for ARHGAP20 using alignment to 1 protein entry:     RHG20_HUMAN:
    FAM13A

    ARHGAP20 for paralogs           About GeneDecksing


    5/6 Pseudogenes.org Pseudogenes for ARHGAP20 (see all 6)
    PGOHUM00000248880 PGOHUM00000245679 PGOHUM00000246060 PGOHUM00000232601 PGOHUM00000249637


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2792 SNPs in ARHGAP20 are shown (see all 2792)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
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    ----------
    rs1120792621,2
    C,F--110447272(+) GCCAAC/TTTTCA 5 -- ds50012Minor allele frequency- T:0.06CSA WA 119
    rs1827763941,2
    --110447404(+) AAACTC/TAGATA 5 -- ds50010--------
    rs766516991,2
    C,F--110447458(+) TAAGAA/GTACTG 5 -- ds50011Minor allele frequency- G:0.08WA 118
    rs1886902521,2
    --110447507(+) CTAAGA/CAAATG 5 -- ds50010--------
    rs2003764981,2
    --110447647(+) CAACA-/TTGTTAAT 5 -- cds10--------
    rs2014860841,2
    --110447650(+) CATTA-/GATTAT 5 -- ds50010--------
    rs1928998291,2
    --110447655(+) AATTAA/TACTCT 5 -- ds50010--------
    rs1850321461,2
    --110447680(+) GTTAGA/CTTATA 5 -- ds50010--------
    rs1462748241,2
    --110447740(+) CAATTA/CTACAA 5 -- ds50010--------
    rs1878423521,2
    C--110447955(+) CAAAGA/CATTTT 5 -- ut310--------

    HapMap Linkage Disequilibrium report for ARHGAP20 (110447766 - 110583912 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/11 variations for ARHGAP20 (see all 11):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2745065CNV Deletion23290073
    esv2745066CNV Deletion23290073
    esv1311954CNV Deletion17803354
    esv2745067CNV Deletion23290073
    nsv898392CNV Loss21882294
    nsv468868CNV Loss19166990
    dgv242n67CNV Loss20364138
    esv21558CNV Loss19812545
    nsv898393CNV Loss21882294
    nsv832266CNV Gain17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609568    OMIM disorders: --

    UniProtKB/Swiss-Prot: RHG20_HUMAN, Q9P2F6
  • Note=A chromosomal aberration involving ARHGAP20 may be a cause of B-cell chronic lymphocytic leukemia
    (B-CLL). Translocation t(X;11)(q21;q23) with BRWD3 does not result in fusion transcripts but disrupts both genes

  • 4 diseases for ARHGAP20:    About MalaCards
    b-cell chronic lymphocytic leukemia    sinusitis    chronic lymphocytic leukemia    leukemia


    ARHGAP20 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ARHGAP20
    Human Genome Epidemiology (HuGE) Navigator: ARHGAP20 (1 document)

    Export disorders for ARHGAP20 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ARHGAP20 gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with ARHGAP20)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of human KIAA1391 and mouse Kiaa1391 genes encoding novel RhoGAP family proteins with RA domain and ANXL repeats. (PubMed id 14532992)1, 2, 3, 9 Katoh M. and Katoh M. (2003)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. Translocation t(X;11)(q13;q23) in B-cell chronic lymphocytic leukemia disrupts two novel genes. (PubMed id 15543602)1, 2 Kalla C.... Lichter P. (2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)1, 2 Nagase T.... Ohara O. (2000)
    6. Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. (PubMed id 23535033)1 Sherva R....Green R.C. (2013)
    7. Genome-wide association analyses identify multiple loc i associated with central corneal thickness and keratoconus. (PubMed id 23291589)1 Lu Y....Wong T.Y. (2013)
    8. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
    9. Heritability and genome-wide association analysis of r enal sinus fat accumulation in the Framingham Heart Study. (PubMed id 22044751)1 Foster M.C....Fox C.S. (2011)
    10. Expression analysis of genes located in the minimally deleted regions of 13q14 and 11q22-23 in chronic lymphocytic leukemia-unexpect ed expression pattern of the RHO GTPase activator ARHGAP20. (PubMed id 21500311)1 Herold T....Bohlander S.K. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57569 HGNC: 18357 AceView: ARHGAP20 Ensembl:ENSG00000137727 euGenes: HUgn57569
    ECgene: ARHGAP20 H-InvDB: ARHGAP20

    (According to HUGE)
    About This Section
    HUGE: KIAA1391

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ARHGAP20 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ARHGAP20 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ARHGAP20 gene:
    Search GeneIP for patents involving ARHGAP20

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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