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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ARHGAP20 Gene

protein-coding GIFtS: 56
GCID: GC11M110447

Rho GTPase activating protein 20

Explore 3 diseases affiliated with
ARHGAP20 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Rho GTPase Activating Protein 20¹ ²		RA And RhoGAP Domain Containing Protein²
KIAA1391¹ ³		Rho GTPase Activating Protein 20 Variant 2²
Rho-Type GTPase-Activating Protein 20² ³		Rho GTPase-Activating Protein 20²
RARHOGAP²

External Ids:	HGNC: 18357¹	Entrez Gene: 57569²	Ensembl: ENSG00000137727⁷	OMIM: 609568⁵	UniProtKB: Q9P2F6³

Export aliases for ARHGAP20 gene to outside databases

Previous GC identifers: GC11M109985 GC11M109952 GC11M106372

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: RHG20_HUMAN, Q9P2F6

Function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000011.9 NC_018922.1 NT_033899.8

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ARHGAP20 gene promoter:
NF-1 RP58 FOXD3 Nkx2-5 Meis-1b C/EBPalpha Egr-2 AREB6 Meis-1a Meis-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ARHGAP20 promoter sequence

Search SABiosciences Chromatin IP Primers for ARHGAP20

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARHGAP20

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q23.1 Ensembl cytogenetic band: 11q23.1 HGNC cytogenetic band: 11q23.2

ARHGAP20 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARHGAP20 gene location

GeneLoc information about chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11M110447: view genomic region (about GC identifiers)

Start:	110,447,766 bp from pter	End:	110,583,912 bp from pter
Size:	136,147 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RHG20_HUMAN, Q9P2F6 (See protein sequence)

Recommended Name: Rho GTPase-activating protein 20

Size: 1191 amino acids; 132608 Da

Developmental stage: Low expression is found in fetal liver

Caution: The translocation involving this gene was originally published as t(X;11)(q13;23) (PubMed:15543602), but BRWD3

is localized to Xq21 and not to Xq13

Sequence caution: Sequence=AAH39340.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;

Sequence=AAH39340.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact; Sequence=BAA92629.1;

Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=BAF84979.1; Type=Erroneous initiation;

Note=Translation N-terminally shortened; Sequence=BAF84979.1; Type=Miscellaneous discrepancy; Note=Probable cloning

artifact;

1 PDB 3D structure from and Proteopedia for ARHGAP20:

3MSX (3D)

Secondary accessions: A8K8C5 B0YIW7 B0YIW8 Q6RJU1 Q6RJU2 Q6RJU3 Q6RJU5 Q8IXS1

Alternative splicing: 4 isoforms: Q9P2F6-1 Q9P2F6-2 Q9P2F6-3 Q9P2F6-4

Explore the universe of human proteins at neXtProt for ARHGAP20: NX_Q9P2F6

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9P2F6

ARHGAP20 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (5 alternative transcripts):

NP_001245344.1 NP_001245345.1 NP_001245346.1 NP_001245347.1 NP_065860.2

ENSEMBL proteins:

ENSP00000260283 ENSP00000437905 ENSP00000432076 ENSP00000436319 ENSP00000436522

ENSP00000431399 ENSP00000349660

Reactome Protein details: Q9P2F6
Human Recombinant Protein Products:

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	Browse ProSpec Recombinant Proteins
	Uscn Proteins for ARHGAP20

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005829	cytosol	TAS	--

ARHGAP20 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for ARHGAP20

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ARHGAP20 for domains About GeneDecksing

5 InterPro domains/families:

IPR008936 Rho_GTPase_activation_prot

IPR001849 Pleckstrin_homology

IPR011993 PH_like_dom

IPR000198 RhoGAP_dom

IPR000159 Ras-assoc

Graphical View of Domain Structure for InterPro Entry Q9P2F6

ProtoNet protein and cluster: Q9P2F6

3 Blocks protein families:

IPB000159 RA domain

IPB000198 RhoGAP domain

IPB001849 Pleckstrin-like

UniProtKB/Swiss-Prot: RHG20_HUMAN, Q9P2F6

Similarity: Contains 1 PH domain

Similarity: Contains 1 Ras-associating domain

Similarity: Contains 1 Rho-GAP domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: RHG20_HUMAN, Q9P2F6

Function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By similarity)

miRNA Products:		OriGene 3'-UTR Clone: ARHGAP20 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ARHGAP20
		8/87 QIAGEN miScript miRNA Assays for microRNAs that regulate ARHGAP20 (see all 87):
		hsa-miR-607 hsa-miR-300 hsa-miR-15a hsa-miR-199a-3p hsa-miR-485-3p hsa-miR-374a hsa-miR-10b* hsa-miR-556-3p

		SwitchGear 3'UTR luciferase reporter plasmid: ARHGAP20 3' UTR sequence

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		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ARHGAP20 (see all 7) OriGene shRNA RFP: ARHGAP20 OriGene siRNA: ARHGAP20
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Gene Editing
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DNA2.0 Custom Protein Engineering Service for ARHGAP20

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARHGAP20

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005096	GTPase activator activity	IEA	--
GO:0005543	phospholipid binding	IEA	--

ARHGAP20 for ontologies About GeneDecksing

4 GenomeRNAi human phenotypes for ARHGAP20:

Abundance of large cells with

Decreased viability of wild-ty

Increased G1 DNA content

Increased gamma-H2AX phosphory

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Cell death signalling via NRAGE, NRIF and NADE

Signaling by Rho GTPases

0.25

Rho GTPase cycle

0.25

Signaling by GPCR

Signal Transduction

0.56

Pathway sources
See GeneCards unified pathways
Show all pathways

3 Reactome Pathways for ARHGAP20

	Signaling by Rho GTPases
	Signal Transduction
	Rho GTPase cycle

ARHGAP20 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for ARHGAP20

STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

5 Interacting proteins for ARHGAP20 (Q9P2F6³ ENSP00000260283⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TERF2	Q15554³, ENSP00000254942⁴	I2D: score=1 STRING: ENSP00000254942
BMPR1B	O00238³	I2D: score=1
RHOA	ENSP00000400175⁴	STRING: ENSP00000400175
GRB2	ENSP00000339007⁴	STRING: ENSP00000339007
SIRT5	ENSP00000368552⁴	STRING: ENSP00000368552

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007264	small GTPase mediated signal transduction	TAS	--
GO:0051056	regulation of small GTPase mediated signal transduction	TAS	--

ARHGAP20 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ARHGAP20
Search CenterWatch for drugs/clinical trials and news about ARHGAP20 / RHG20

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ARHGAP20 gene (5 alternative transcripts):

NM_001258415.1 NM_001258416.1 NM_001258417.1 NM_001258418.1 NM_020809.3

Unigene Cluster for ARHGAP20:

Rho GTPase activating protein 20

Hs.6136 [show with all ESTs]

Unigene Representative Sequence: NM_001258415

7 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000260283(uc001pkz.1 uc009yyb.1) ENST00000529591(uc001plb.2)

ENST00000524756(uc001pky.1) ENST00000528829 ENST00000533353(uc001pla.1)

ENST00000527598 ENST00000357139

miRNA Products:		OriGene 3'-UTR Clone: ARHGAP20 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ARHGAP20
		8/87 QIAGEN miScript miRNA Assays for microRNAs that regulate ARHGAP20 (see all 87):
		hsa-miR-607 hsa-miR-300 hsa-miR-15a hsa-miR-199a-3p hsa-miR-485-3p hsa-miR-374a hsa-miR-10b* hsa-miR-556-3p

		SwitchGear 3'UTR luciferase reporter plasmid: ARHGAP20 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Additional cDNA sequence:

AB037812.1 AK292290.1 AK307602.1 AY496263.1 AY496264.1 AY496265.1 AY496266.1 AY496267.1

BC039340.1

5 DOTS entries:

DT.312981 DT.102823760 DT.95139488 DT.102823761 DT.102823762

24/46 AceView cDNA sequences (see all 46):

BC039340 BX095222 Z39921 AY496263 BX508298 AY496267 AY496264 AY496265

AY496266 AB037812 NM_020809 AI222036 AI300211 AA846778 CF552743 AI936560

AA884003 BX119603 BQ003257 AW205620 AI698688 BI464112 Z43854 AW892501

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ARHGAP20 (see all 6) About this scheme

ExUns:	1	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12	^	13	^	14	^	15	^	16	^	17	^	18	^	19	^	20a	·	20b	^	21
SP1:			-		-		-																								-
SP2:							-		-																						-
SP3:			-		-		-		-																						-
SP4:					-		-		-																						-
SP5:									-																						-

ECgene alternative splicing isoforms for ARHGAP20

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ARHGAP20 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGTCTGTTA

About this image

ARHGAP20 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Testis

Seminiferous Tubules

Secondary Spermatocyte

Germ Cells, Male Gametocytes

Kidney

Interstitial Stroma

Kidney

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

Sclerotome cells (Primary Cell)

Bone, Cartilage, Somite

Cartilage-like cells (Differentiation of s...)

Cartilage

See ARHGAP20 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ARHGAP20

SOURCE GeneReport for Unigene cluster: Hs.6136

UniProtKB/Swiss-Prot: RHG20_HUMAN, Q9P2F6

Tissue specificity: Expressed predominantly in the brain. Lower expression is found in lymph nodes

SABiosciences Custom PCR Arrays for ARHGAP20

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for ARHGAP20 gene from 6/18 species (see all 18) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	ARHGAP20¹	Rho GTPase activating protein 20	64.29(n) 58(a)		418962 XM_417154.3 XP_417154.2
lizard (Anolis carolinensis)	Reptilia	ARHGAP20⁶ --	--	60(a) 56(a)	1 ↔ 1 possible ortholog	3(186531263-186571074) GL343465.1(561800-565391)
tropical clawed frog (Xenopus tropicalis)	Amphibia	Str.4409²	Transcribed sequence with weak similarity to protein more	73.12(n)		AL850639.2
zebrafish (Danio rerio)	Actinopterygii	arhgap20¹	Rho GTPase activating protein 20	56.94(n) 49.74(a)		796434 XM_001336727.4 XP_001336763.2
honey bee (Apis mellifera)	Insecta	--	--	24(a)	1 → many	Group3.17(91335-95057)
worm (Caenorhabditis elegans)	Secernentea	rga-2⁶	Rho GTPase Activating protein family member (rga-2...	18(a)	1 → many	I(11979431-11985646)

ENSEMBL Gene Tree for ARHGAP20 (if available)
TreeFam Gene Tree for ARHGAP20 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for ARHGAP20 gene

TAGAP²

1 SIMAP similar gene for ARHGAP20 using alignment to 1 protein entry: RHG20_HUMAN:

FAM13A

ARHGAP20 for paralogs About GeneDecksing

5/6 Pseudogenes.org Pseudogenes for ARHGAP20 (see all 6)
PGOHUM00000248880 PGOHUM00000245679 PGOHUM00000246060 PGOHUM00000232601 PGOHUM00000249637

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 11 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs112079262^1,2		--	110447272(+)	`GCCAAC/TTTTCA`	5	--	ds500¹		2		CSA WA	119
rs182776394^1,2		--	110447404(+)	`AAACTC/TAGATA`	5	--	ds500¹		0	--	--	--	--
rs76651699^1,2	C,F,	--	110447458(+)	`TAAGAA/GTACTG`	5	--	ds500¹		1		WA	118
rs188690252^1,2		--	110447507(+)	`CTAAGA/CAAATG`	5	--	ds500¹		0	--	--	--	--
rs200376498^1,2		--	110447647(+)	`CAACA-/TTGTTAAT`	5	--	ds500¹		0	--	--	--	--
rs201486084^1,2		--	110447650(+)	`CATTA-/GATTAT`	5	--	ds500¹		0	--	--	--	--
rs192899829^1,2		--	110447655(+)	`AATTAA/TACTCT`	5	--	ds500¹		0	--	--	--	--
rs185032146^1,2		--	110447680(+)	`GTTAGA/CTTATA`	5	--	ds500¹		0	--	--	--	--
rs146274824^1,2		--	110447740(+)	`CAATTA/CTACAA`	5	--	ds500¹		0	--	--	--	--
rs187842352^1,2		--	110447955(+)	`CAAAGA/CATTTT`	5	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for ARHGAP20 (110447766 - 110583912 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for ARHGAP20
2 CNVs: 71378 71377
1 Indel: 24624

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ARHGAP20

DNA2.0 Custom Variant and Variant Library Synthesis for ARHGAP20

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ARHGAP20 for disorders About GeneDecksing

OMIM gene information: 609568 OMIM disorders: --

UniProtKB/Swiss-Prot: RHG20_HUMAN, Q9P2F6

Note=A chromosomal aberration involving ARHGAP20 may be a cause of B-cell chronic lymphocytic leukemia

(B-CLL). Translocation t(X;11)(q21;q23) with BRWD3 does not result in fusion transcripts but disrupts both genes

3 diseases for ARHGAP20: About MalaCards

chronic lymphocytic leukemia lymphocytic leukemia leukemia

Human Genome Epidemiology (HuGE) Navigator: ARHGAP20 (1 document)

Export disorders for ARHGAP20 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for ARHGAP20 gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with ARHGAP20)

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Identification and characterization of human KIAA1391 and mouse Kiaa1391 genes encoding novel RhoGAP family proteins with RA domain and ANXL repeats. (PubMed id 14532992)^{1, 2, 3, 9} Katoh M. and Katoh M. (2003)
Translocation t(X;11)(q13;q23) in B-cell chronic lymphocytic leukemia disrupts two novel genes. (PubMed id 15543602)^{1, 2} Kalla C.... Lichter P. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)^{1, 2} Nagase T.... Ohara O. (2000)
Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)¹ Lin Y.Y....Boeke J.D. (2012)
Expression analysis of genes located in the minimally deleted regions of 13q14 and 11q22-23 in chronic lymphocytic leukemia-unexpect ed expression pattern of the RHO GTPase activator ARHGAP20. (PubMed id 21500311)¹ Herold T....Bohlander S.K. (2011)
Heritability and genome-wide association analysis of r enal sinus fat accumulation in the Framingham Heart Study. (PubMed id 22044751)¹ Foster M.C....Fox C.S. (2011)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
The protein network surrounding the human telomere re peat binding factors TRF1, TRF2, and POT1. (PubMed id 20811636)¹ Giannone R.J....Liu Y. (2010)
RA-RhoGAP, Rap-activated Rho GTPase-activating protein implicated in neurite outgrowth through Rho. (PubMed id 16014623)¹ Yamada T....Takai Y. (2005)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 57569	HGNC: 18357	AceView: ARHGAP20	Ensembl:ENSG00000137727	euGenes: HUgn57569
ECgene: ARHGAP20	H-InvDB: ARHGAP20

(According to HUGE)
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HUGE: KIAA1391

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for ARHGAP20	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for ARHGAP20	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for ARHGAP20 gene
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Patent Information for ARHGAP20 gene:
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ARHGAP20 Gene

Rho GTPase activating protein 20

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ARHGAP20 Gene

Rho GTPase activating protein 20

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