Aliases for ARHGAP10 Gene
External Ids for ARHGAP10 Gene
Previous GeneCards Identifiers for ARHGAP10 Gene
GeneCards Summary for ARHGAP10 Gene
ARHGAP10 (Rho GTPase Activating Protein 10) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by Rho GTPases. GO annotations related to this gene include GTPase activator activity. An important paralog of this gene is ARHGAP21.
UniProtKB/Swiss-Prot for ARHGAP10 Gene
GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).