Aliases for ARHGAP10 Gene
External Ids for ARHGAP10 Gene
Previous GeneCards Identifiers for ARHGAP10 Gene
GeneCards Summary for ARHGAP10 Gene
ARHGAP10 (Rho GTPase Activating Protein 10) is a Protein Coding gene. Among its related pathways are Bacterial invasion of epithelial cells and Apoptotic cleavage of cellular proteins. GO annotations related to this gene include GTPase activator activity. An important paralog of this gene is ARHGAP9.
UniProtKB/Swiss-Prot for ARHGAP10 Gene
GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).