Aliases for ARHGAP10 Gene
External Ids for ARHGAP10 Gene
Previous GeneCards Identifiers for ARHGAP10 Gene
GeneCards Summary for ARHGAP10 Gene
ARHGAP10 (Rho GTPase Activating Protein 10) is a Protein Coding gene. Among its related pathways are Bacterial invasion of epithelial cells and CDK-mediated phosphorylation and removal of Cdc6. GO annotations related to this gene include GTPase activator activity. An important paralog of this gene is ARHGAP26.
UniProtKB/Swiss-Prot for ARHGAP10 Gene
GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).