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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ARFRP1 Gene

protein-coding   GIFtS: 56
GCID: GC20M062331

ADP-Ribosylation Factor Related Protein 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
ADP-Ribosylation Factor Related Protein 11 2     ADP-Ribosylation Factor-Related Protein 12
ARP2 3     Helicase-Like Protein NHL2
ARF-Related Protein 12 3     SCG10 Like-Protein2
ARL182     ARP13
Arp12     

External Ids:    HGNC: 6621   Entrez Gene: 101392   Ensembl: ENSG000001012467   OMIM: 6046995   UniProtKB: Q137953   

Export aliases for ARFRP1 gene to outside databases

Previous GC identifers: GC20M062208 GC20M063010 GC20M063056 GC20M063058 GC20M061800 GC20M059062


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ARFRP1 Gene:
The protein encoded by this gene is a membrane-associated GTP-ase which localizes to the plasma membrane and is
related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) proteins. This gene plays a role in membrane
trafficking between the trans-Golgi network and endosomes. Alternatively spliced transcript variants encoding
different isoforms have been identified. (provided by RefSeq, May 2012)

GeneCards Summary for ARFRP1 Gene: 
ARFRP1 (ADP-ribosylation factor related protein 1) is a protein-coding gene. Diseases associated with ARFRP1 include wiskott-aldrich syndrome, and otosclerosis. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is ARL13A.

UniProtKB/Swiss-Prot: ARFRP_HUMAN, Q13795
Function: Possibly involved in plasma membrane-related signaling events

Gene Wiki entry for ARFRP1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NC_018931.2  NT_011333.6  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ARFRP1 gene promoter:
         ATF-2   MEF-2   MEF-2A   CRE-BP1   HEN1   COMP1   HSF1short   aMEF-2   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidARFRP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for ARFRP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARFRP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.3   Ensembl cytogenetic band:  20q13.33   HGNC cytogenetic band: 20q13.3

ARFRP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARFRP1 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M062331:  view genomic region     (about GC identifiers)

Start:
62,329,995 bp from pter      End:
62,339,355 bp from pter
Size:
9,361 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ARFRP_HUMAN, Q13795 (See protein sequence)
Recommended Name: ADP-ribosylation factor-related protein 1  
Size: 201 amino acids; 22614 Da
Subunit: Interacts with SYS1
Subcellular location: Golgi apparatus
Secondary accessions: B7ZKX7 E1P5J9 Q6IBQ0
Alternative splicing: 2 isoforms:  Q13795-1   Q13795-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ARFRP1: NX_Q13795

Explore proteomics data for ARFRP1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q13795

  • ARFRP1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ARFRP1 Protein Expression
    REFSEQ proteins (8 alternative transcripts): 
    NP_001128230.1  NP_001254473.1  NP_001254474.1  NP_001254475.1  NP_001254476.1  NP_001254477.1  NP_001254478.1  NP_003215.1  

    ENSEMBL proteins: 
     ENSP00000217224   ENSP00000326884   ENSP00000352746   ENSP00000403942  

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    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus ----
    GO:0005737cytoplasm ----
    GO:0005794Golgi apparatus IDA19224922
    GO:0005802trans-Golgi network IDA16129887

    ARFRP1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5 InterPro protein domains:
     IPR027417 P-loop_NTPase
     IPR006689 Small_GTPase_ARF/SAR
     IPR024156 Small_GTPase_ARF
     IPR005225 Small_GTP-bd_dom
     IPR001806 Small_GTPase

    Graphical View of Domain Structure for InterPro Entry Q13795

    ProtoNet protein and cluster: Q13795

    1 Blocks protein domain: IPB006688 ADP-ribosylation factor

    UniProtKB/Swiss-Prot: ARFRP_HUMAN, Q13795
    Similarity: Belongs to the small GTPase superfamily. Arf family


    ARFRP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ARFRP_HUMAN, Q13795
    Function: Possibly involved in plasma membrane-related signaling events

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity TAS8530503
    GO:0004871signal transducer activity ----
    GO:0005515protein binding IPI11438518
    GO:0005525GTP binding IEA--
    GO:0019001guanyl nucleotide binding ----
         
    ARFRP1 for ontologies           About GeneDecksing


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Arfrp1):
     cellular  embryogenesis  mortality/aging 

    ARFRP1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Arfrp1tm1Asch for ARFRP1

       inGenious Targeting Laboratory - Custom generated mouse model solutions for ARFRP1 
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    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARFRP1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ARFRP1

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5/80 Interacting proteins for ARFRP1 (Q137953 ENSP000003268844) via UniProtKB, MINT, STRING, and/or I2D (see all 80)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CYTH1Q154383, ENSP000003543984I2D: score=3 STRING: ENSP00000354398
    SMAD4Q134853, ENSP000003415514I2D: score=4 STRING: ENSP00000341551
    GTF2BQ004033I2D: score=5 
    UNC50Q53HI13I2D: score=5 
    EEF1A1P681043I2D: score=3 
    About this table

    Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006184GTP catabolic process TAS8530503
    GO:0006886intracellular protein transport ----
    GO:0007165signal transduction TAS8530503
    GO:0007186G-protein coupled receptor signaling pathway ----
    GO:0007264small GTPase mediated signal transduction IEA--

    ARFRP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ARFRP1 (ARFRP)

    Search CenterWatch for drugs/clinical trials and news about ARFRP1 / ARFRP

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ARFRP1 gene (8 alternative transcripts): 
    NM_001134758.2  NM_001267544.1  NM_001267545.1  NM_001267546.1  NM_001267547.1  NM_001267548.1  NM_001267549.1  NM_003224.4  

    Unigene Cluster for ARFRP1:

    ADP-ribosylation factor related protein 1
    Hs.389277  [show with all ESTs]
    Unigene Representative Sequence: AK095962
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000485858 ENST00000217224 ENST00000324228 ENST00000424545 ENST00000359715(uc002yga.3)
    ENST00000440854(uc002ygc.3 uc011abg.2 uc011abh.2 uc002ygf.3 uc011abf.2 uc002ygh.4)

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    hsa-miR-511 hsa-miR-361-3p hsa-miR-561
    SwitchGear 3'UTR luciferase reporter plasmidARFRP1 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AK095962.1 BC021023.1 BC092480.1 BC093967.1 BC143447.1 BC143448.1 BC143467.1 BC143472.1 
    BC143477.1 BT019624.1 BT019663.1 CR456752.1 NR_051954.1 NR_051955.1 NR_051956.1 NR_051957.1 
    NR_051958.1 X91504.1 

    21 DOTS entries:

    DT.100809266  DT.100718428  DT.216485  DT.100746777  DT.92435431  DT.100809281  DT.95255133  DT.100809284 
    DT.100862137  DT.100809285  DT.109754  DT.97763700  DT.100809283  DT.100746778  DT.100809272  DT.40114701 
    DT.100836134  DT.100845109  DT.92435432  DT.95255114  DT.95255137 

    24/322 AceView cDNA sequences (see all 322):

    BX447173 BU737761 CR598656 CK902106 AI356594 CR590403 CR595028 CR591044 
    BX363231 CR613687 CR596379 CR606714 CR602845 AL533893 T32755 BM449604 
    BQ073457 BX404499 CR602635 BM920497 BF435047 BX363907 CR596566 CA489361 

    GeneLoc Exon Structure

    5/15 Alternative Splicing Database (ASD) splice patterns (SP) for ARFRP1 (see all 15)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b · 11c · 11d · 11e ·
    SP1:                                            -     -           -                       -     -                 -     -                                       
    SP2:                                            -     -           -                       -     -                 -     -                                       
    SP3:                                                  -           -                       -     -                 -     -                                       
    SP4:                                            -     -     -     -                       -     -                 -     -                                       
    SP5:                                            -     -           -                       -     -                 -     -                                       

    ExUns: 11f · 11g · 11h · 11i
    SP1:                        
    SP2:                        
    SP3:                        
    SP4:                        
    SP5:                        


    ECgene alternative splicing isoforms for ARFRP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ARFRP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTCCCAAAGG
    ARFRP1 Expression
    About this image


    See ARFRP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ARFRP1

    SOURCE GeneReport for Unigene cluster: Hs.389277

    UniProtKB/Swiss-Prot: ARFRP_HUMAN, Q13795
    Tissue specificity: Found in most tissues

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARFRP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ARFRP1 gene from 10/23 species (see all 23)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Arfrp11 , 5 ADP-ribosylation factor related protein 11, 5 88.56(n)1
    97.01(a)1
      2 (103.63 cM)5
    766881  NM_001165991.11  NP_001159463.11 
     1813578335 
    chicken
    (Gallus gallus)
    Aves ARFRP11 ADP-ribosylation factor related protein 1 78.11(n)
    91.04(a)
      419261  XM_417433.3  XP_417433.2 
    lizard
    (Anolis carolinensis)
    Reptilia ARFRP16
    Uncharacterized protein
    90(a)
    1 ↔ 1
    GL343401.1(902361-917580)
    African clawed frog
    (Xenopus laevis)
    Amphibia cg7039-prov2 hypothetical protein MGC64400 79.6(n)    BC054219.1 
    zebrafish
    (Danio rerio)
    Actinopterygii arfrp11 ADP-ribosylation factor related protein 1 78.23(n)
    87.86(a)
      503602  NM_001013289.1  NP_001013307.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG70391 , 3 ARF small monomeric GTPase3
    CG70391
    63(a)3
    66.67(n)1
    63.82(a)1
      8C93
    318411  NM_132298.41  NP_572526.11 
    worm
    (Caenorhabditis elegans)
    Secernentea Y54E10BR.23
    CELE_Y54E10BR.21
    Protein Y54E10BR.21 40(a)3
    50(n)1
    40.66(a)1
      I(3033007-3033825)3
    1718781  NM_058693.41  NP_491094.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ARL3(YPL051W)4
    ARL31
    GTPase of the Ras superfamily required to recruit Arl1p more4
    Arl3p1
    49.4(n)1
    49.22(a)1
      16(459963-460559)4
    8560561, 4  NP_015274.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons GB11 GTP-binding protein 1 50.28(n)
    46.41(a)
      835297  NM_124600.2  NP_200034.1 
    rice
    (Oryza sativa)
    Liliopsida Os03g03923001 hypothetical protein 51.16(n)
    42.78(a)
      4333026  NM_001056818.1  NP_001050283.1 


    ENSEMBL Gene Tree for ARFRP1 (if available)
    TreeFam Gene Tree for ARFRP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ARFRP1 gene
    ARL13A2  ARL13B2  
    18/25 SIMAP similar genes for ARFRP1 using alignment to 4 protein entries:     ARFRP_HUMAN (see all proteins) (see all similar genes):
    ARL5A    ARL2    ARL5B    ARF1    ARL14    ARF6
    TRIM23    ARL6    ARF4    ARF5    ARF3    ARL1
    ARL4A    ARL3    ARL5C    ARL13B    ARL4D    ARL8A

    ARFRP1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/197 SNPs in ARFRP1 are shown (see all 197)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0365594
    A breast cancer sample4--see VAR_0365592 L V mis40--------
    rs1875794211,2
    --59073834(+) TTTTTG/TGAGAT 1 -- us2k10--------
    rs48093251,2
    C,A,H--59073839(+) tgagaC/Tggagt 1 -- us2k18Minor allele frequency- T:0.00NA WA CSA 16
    rs1909359891,2
    --59073847(+) AGTCTC/TGTTCT 1 -- us2k10--------
    rs1833912271,2
    --59073849(+) TCTTGC/TTCTGT 1 -- us2k10--------
    rs1866359031,2
    --59073855(+) TCTGTA/TGCCCA 1 -- us2k10--------
    rs1926908281,2
    C--59073902(+) AGCTCC/TGCCTC 1 -- us2k10--------
    rs1845431541,2
    --59074007(+) GAGACA/GGGGTT 13 -- us2k10--------
    rs1881818691,2
    --59074170(+) AGTGGC/TGCAAT 13 -- us2k10--------
    rs778296601,2
    C--59074233(+) CCTCCC/TGAGTA 12 -- us2k11Minor allele frequency- T:0.00NA 2

    HapMap Linkage Disequilibrium report for ARFRP1 (62329995 - 62339355 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/17 variations for ARFRP1 (see all 17):    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv913250CNV Loss21882294
    dgv4647n71CNV Loss21882294
    dgv4644n71CNV Loss21882294
    dgv4645n71CNV Loss21882294
    nsv913213CNV Loss21882294
    dgv4618n71CNV Loss21882294
    nsv828801CNV Loss20364138
    dgv4646n71CNV Loss21882294
    nsv470563CNV Loss18288195
    nsv913190CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 604699    OMIM disorders: --

    3 diseases for ARFRP1:    About MalaCards
    wiskott-aldrich syndrome    otosclerosis    neuronitis

    1 disease from the University of Copenhagen DISEASES database for ARFRP1:
    Otosclerosis

    ARFRP1 for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for ARFRP1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    wiskott-aldrich syndrome 65 1 15834156 (1)

    Genetic Association Database (GAD): ARFRP1

    Export disorders for ARFRP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ARFRP1 gene, integrated from 9 sources (see all 30):
    (articles sorted by number of sources associating them with ARFRP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ARP is a plasma membrane-associated Ras-related GTPase with remote similarity to the family of ADP-ribosylation factors. (PubMed id 8530503)1, 2, 3 Schuermann A.... Joost H.-G. (1995)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Targeting of the Arf-like GTPase Arl3p to the Golgi requires N- terminal acetylation and the membrane protein Sys1p. (PubMed id 15077113)1, 2 Behnia R.... Munro S. (2004)
    4. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    5. Overexpression of M68/DcR3 in human gastrointestinal tract tumors independent of gene amplification and its location in a four-gene cluster. (PubMed id 10655513)1, 2 Bai C.... Caskey C.T. (2000)
    6. The Identification of Novel Proteins That Interact Wit h the GLP-1 Receptor and Restrain its Activity. (PubMed id 23864651)1 Huang X....Wheeler M.B. (2013)
    7. The GTPase ARFRP1 controls the lipidation of chylomicr ons in the Golgi of the intestinal epithelium. (PubMed id 22505585)1 Jaschke A....Schurmann A. (2012)
    8. Differential effects of depletion of ARL1 and ARFRP1 on membrane trafficking between the trans-Golgi network and endosomes. (PubMed id 19224922)1 Nishimoto-Morita K....Nakayama K. (2009)
    9. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
    10. Knockout of Arfrp1 leads to disruption of ARF-like1 (ARL1) targeting to the trans-Golgi in mouse embryos and HeLa cells. (PubMed id 17127620)1 Zahn C....Schurmann A. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10139 HGNC: 662 AceView: ARFRP1 Ensembl:ENSG00000101246 euGenes: HUgn10139
    ECgene: ARFRP1 H-InvDB: ARFRP1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ARFRP1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ARFRP1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ARFRP1 gene:
    Search GeneIP for patents involving ARFRP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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