Aliases for ARFRP1 Gene
External Ids for ARFRP1 Gene
Previous GeneCards Identifiers for ARFRP1 Gene
The protein encoded by this gene is a membrane-associated GTP-ase which localizes to the plasma membrane and is related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) proteins. This gene plays a role in membrane trafficking between the trans-Golgi network and endosomes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, May 2012]
GeneCards Summary for ARFRP1 Gene
ARFRP1 (ADP Ribosylation Factor Related Protein 1) is a Protein Coding gene. Among its related pathways are Vesicle-mediated transport and Retrograde transport at the Trans-Golgi-Network. GO annotations related to this gene include GTP binding and signal transducer activity. An important paralog of this gene is ARL13B.
UniProtKB/Swiss-Prot for ARFRP1 Gene
Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver.