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ARFIP1 Gene

protein-coding   GIFtS: 54
GCID: GC04P153701

ADP-Ribosylation Factor Interacting Protein 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
ADP-Ribosylation Factor Interacting Protein 11 2
Arfaptin 11
HSU525212
arfaptin-12
ADP-Ribosylation Factor-Interacting Protein 13

External Ids:    HGNC: 214961   Entrez Gene: 272362   Ensembl: ENSG000001641447   OMIM: 6059285   UniProtKB: P533673   

Export aliases for ARFIP1 gene to outside databases

Previous GC identifers: GC04P154167 GC04P154278 GC04P154058 GC04P153920 GC04P149427


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ARFIP1 Gene:
ARFIP1 (ADP-ribosylation factor interacting protein 1) is a protein-coding gene. Diseases associated with ARFIP1 include fibrosarcoma, and cholera. GO annotations related to this gene include identical protein binding and protein domain specific binding. An important paralog of this gene is ARFIP2.

UniProtKB/Swiss-Prot: ARFP1_HUMAN, P53367
Function: Putative target protein of ADP-ribosylation factor

Gene Wiki entry for ARFIP1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000004.12  NC_018915.2  NT_016354.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the ARFIP1 gene promoter:
         STAT1   STAT1beta   FOXD3   XBP-1   STAT1alpha   MEF-2A   HFH-1   HSF2   Chx10   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidARFIP1 promoter sequence
   Search Chromatin IP Primers for ARFIP1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ARFIP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q31.3   Ensembl cytogenetic band:  4q31.3   HGNC cytogenetic band: 4q31.3

ARFIP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARFIP1 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P153701:  view genomic region     (about GC identifiers)

Start:
153,701,089 bp from pter      End:
153,839,615 bp from pter
Size:
138,527 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: ARFP1_HUMAN, P53367 (See protein sequence)
Recommended Name: Arfaptin-1  
Size: 373 amino acids; 41738 Da
Subunit: Interacts with non-myristoylated GTP-bound ARF3, but not to GDP-bound ARF3, and also to ARF1. Binds with
lower affinity to ARF5 and with very little affinity to ARF6
Secondary accessions: Q2M2X4 Q3SYL4 Q9Y2X6
Alternative splicing: 2 isoforms:  P53367-1   P53367-2   

Explore the universe of human proteins at neXtProt for ARFIP1: NX_P53367

Explore proteomics data for ARFIP1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys353
  • Modification sites at PhosphoSitePlus

  • See ARFIP1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (6 alternative transcripts): 
    NP_001020764.1  NP_001020766.1  NP_001274360.1  NP_001274361.1  NP_001274362.1  NP_055262.1  

    ENSEMBL proteins: 
     ENSP00000395083   ENSP00000396653   ENSP00000384189   ENSP00000348360   ENSP00000296557  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR027267 AH/BAR-dom
     IPR010504 AH_dom

    Graphical View of Domain Structure for InterPro Entry P53367

    ProtoNet protein and cluster: P53367

    1 Blocks protein domain: IPB010504 Arfaptin-like

    UniProtKB/Swiss-Prot: ARFP1_HUMAN, P53367
    Similarity: Contains 1 AH domain


    ARFIP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ARFP1_HUMAN, P53367
    Function: Putative target protein of ADP-ribosylation factor

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0019904protein domain specific binding IEA--
    GO:0042802identical protein binding IEA--
         
    ARFIP1 for ontologies           About GeneDecksing


    Animal Models:
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    miRNA
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    miRTarBase miRNAs that target ARFIP1:
    hsa-mir-155-5p (MIRT001571), hsa-mir-877-3p (MIRT037039), hsa-mir-23b-3p (MIRT023478), hsa-mir-124-3p (MIRT002668)

    Block miRNA regulation of human, mouse, rat ARFIP1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ARFIP1 (see all 28):
    hsa-miR-320a hsa-miR-148b hsa-miR-2110 hsa-miR-301a hsa-miR-373* hsa-miR-548l hsa-miR-223 hsa-miR-124
    SwitchGear 3'UTR luciferase reporter plasmidARFIP1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ARFIP1

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARFIP1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    golgi apparatus5
    nucleus2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IDA9038142
    GO:0005829cytosol IDA9038142

    ARFIP1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ARFIP1
    Interactions:

        GeneGlobe Interaction Network for ARFIP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    Selected Interacting proteins for ARFIP1 (P533672, 3 ENSP000002965574) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARF1P840773, ENSP000002721024I2D: score=2 STRING: ENSP00000272102
    ARF3P612043, ENSP000002566824I2D: score=2 STRING: ENSP00000256682
    ARF5P840853, ENSP000000002334I2D: score=1 STRING: ENSP00000000233
    EYA2O001673I2D: score=3 
    SLC2A4P146723I2D: score=3 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006886intracellular protein transport IDA12606037
    GO:0050708regulation of protein secretion IDA12606037

    ARFIP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ARFIP1 (ARFP1)

    1 HMDB Compound for ARFIP1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ARFIP1 gene (6 alternative transcripts): 
    NM_001025593.2  NM_001025595.2  NM_001287431.1  NM_001287432.1  NM_001287433.1  NM_014447.3  

    Unigene Cluster for ARFIP1:

    ADP-ribosylation factor interacting protein 1
    Hs.416089  [show with all ESTs]
    Unigene Representative Sequence: NM_001025595
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000451320(uc003inc.3) ENST00000429148 ENST00000405727 ENST00000356064
    ENST00000510831 ENST00000509413 ENST00000511289 ENST00000513361 ENST00000514499
    ENST00000510497 ENST00000353617(uc003imz.3 uc003inb.3 uc003ina.3 uc011cij.2)

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate ARFIP1 (see all 28):
    hsa-miR-320a hsa-miR-148b hsa-miR-2110 hsa-miR-301a hsa-miR-373* hsa-miR-548l hsa-miR-223 hsa-miR-124
    SwitchGear 3'UTR luciferase reporter plasmidARFIP1 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for ARFIP1
    Predesigned siRNA for gene silencing in human, mouse, rat ARFIP1
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    OriGene ORF clones in mouse, rat for ARFIP1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): ARFIP1 (NM_014447)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ARFIP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARFIP1
    Primer
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    OriGene qPCR primer pairs and template standards for ARFIP1
    OriGene qSTAR qPCR primer pairs in human, mouse for ARFIP1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ARFIP1
      QuantiTect SYBR Green Assays in human, mouse, rat ARFIP1
      QuantiFast Probe-based Assays in human, mouse, rat ARFIP1

    Additional mRNA sequence: 

    AF124489.1 AK096509.1 AK290472.1 AK299600.1 AK304141.1 AK316125.1 BC103759.1 BC105114.1 
    BC105116.1 BC143675.1 BC143676.1 U52521.1 

    11 DOTS entries:

    DT.95164065  DT.86853897  DT.315763  DT.91764443  DT.121269321  DT.121269305  DT.121269311  DT.121269329 
    DT.40131068  DT.99976018  DT.99988510 

    Selected AceView cDNA sequences (see all 155):

    NM_014447 AI498016 CR602975 AI869457 AU124900 BF224424 CB269796 BM769127 
    CD643329 AF124489 U52521 BM856182 BE350335 AW275028 BQ428470 AW131141 
    AI653822 R27400 AI097610 BU166318 AA376853 AI360802 AA971915 BM836677 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ARFIP1 (see all 14)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9 ^ 10 ^ 11 ^ 12a · 12b · 12c · 12d ^ 13a · 13b · 13c · 13d · 13e ^ 14 ^ 15 ^
    SP1:                    -     -     -     -     -     -                 -     -                                                                             -   
    SP2:                    -     -     -     -     -     -                 -     -           -                                                                 -   
    SP3:                          -     -     -     -     -                 -     -           -                 -     -     -                                   -   
    SP4:                          -     -     -     -     -                 -     -                                         -     -                                 
    SP5:                          -     -     -     -     -                 -     -                                                                                 

    ExUns: 16 ^ 17 ^ 18a · 18b · 18c · 18d
    SP1:  -                                 
    SP2:  -                                 
    SP3:  -                                 
    SP4:                                    
    SP5:                                    


    ECgene alternative splicing isoforms for ARFIP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ARFIP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AACTTTGTGG
    ARFIP1 Expression
    About this image


    ARFIP1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Blood (Hematopoietic System)
             Granulocytes Peripheral Blood
    ARFIP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ARFIP1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.416089

    UniProtKB/Swiss-Prot: ARFP1_HUMAN, P53367
    Tissue specificity: Ubiquitously expressed. Higher levels in liver, pancreas, placenta, skeletal muscle and heart

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    QuantiFast Probe-based Assays in human, mouse, rat ARFIP1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARFIP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ARFIP1 gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Arfip11 , 5 ADP-ribosylation factor interacting protein 11, 5 89.81(n)1
    92.49(a)1
      3 (37.70 cM)5
    998891  NM_001081093.11  NP_001074562.11 
     844960935 
    chicken
    (Gallus gallus)
    Aves ARFIP11 ADP-ribosylation factor interacting protein 1 84.19(n)
    90.03(a)
      770884  NM_001252398.1  NP_001239327.1 
    lizard
    (Anolis carolinensis)
    Reptilia ARFIP16
    ADP-ribosylation factor interacting protein 1
    83(a)
    1 ↔ 1
    5(131436020-131491813)
    African clawed frog
    (Xenopus laevis)
    Amphibia loc60382-prov2 arfaptin 1 78.07(n)    BC045010.1 
    zebrafish
    (Danio rerio)
    Actinopterygii idibd20772 Danio rerio cDNA clone MGC66341 IMAGE5603861, complete more 77.43(n)    BC054687.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG171846
    --
    44(a)
    1 → many
    3R(7058151-7060907)
    worm
    (Caenorhabditis elegans)
    Secernentea F54C8.76
    Protein F54C8.7, isoform b
    29(a)
    1 → many
    III(9451591-9454062) WBGene00010040


    ENSEMBL Gene Tree for ARFIP1 (if available)
    TreeFam Gene Tree for ARFIP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ARFIP1 gene
    ARFIP22  
    1 SIMAP similar gene for ARFIP1 using alignment to 3 protein entries:     ARFP1_HUMAN (see all proteins):
    ARFIP2

    ARFIP1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ARFIP1 (see all 2487)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1872143971,2
    --153702919(+) TACTTC/TAGTTT 3 -- int10--------
    rs766043381,2
    C,F--153703080(+) TTTTTT/CCCCCC 3 -- int11Minor allele frequency- C:0.07WA 118
    rs1929491821,2
    C--153703104(+) CCATTA/GTTTTT 3 -- int10--------
    rs1831375121,2
    --153703126(+) AAAGGA/CGATAT 3 -- int10--------
    rs764649631,2
    C--153703203(+) TGTGT-/GGTGTA 3 -- int10--------
    rs110998531,2
    C,F,H--153703306(+) AGATAT/CATAGC 3 -- int120Minor allele frequency- C:0.33NS EA NA CSA WA 2346
    rs715982141,2
    C--153703376(+) TAGGG-/GTGTGT
    /GTGTGTGT
    GTGTG
    3 -- int11NA 2
    rs1399701871,2
    C--153703376(+) TAGGG-/GTGTGTG
    TGTGTGTGT
    GTGTG
    3 -- int10--------
    rs738652401,2
    C--153703377(+) AGGGGG/TGTGTG 3 -- int11Minor allele frequency- T:0.50WA 2
    rs1125444701,2
    C--153703465(+) CAGGGT/ATTCTT 3 -- int11Minor allele frequency- A:0.50CSA 2

    HapMap Linkage Disequilibrium report for ARFIP1 (153701089 - 153839615 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for ARFIP1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv522511CNV Loss19592680
    nsv516652CNV Loss19592680
    nsv520249CNV Loss19592680
    nsv830117CNV Gain17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605928    OMIM disorders: --

    5 diseases for ARFIP1:    
    About MalaCards
    fibrosarcoma    cholera    intrahepatic cholangiocarcinoma    cholangiocarcinoma
    neuroblastoma


    ARFIP1 for disorders           About GeneDecksing


    Export disorders for ARFIP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ARFIP1 gene, integrated from 10 sources (see all 26):
    (articles sorted by number of sources associating them with ARFIP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Arfaptin 1 forms a complex with ADP-ribosylation factor and inhibits phospholipase D. (PubMed id 10413101)1, 2, 3, 9 Williger B.-T.... Exton J.H. (FEBS Lett. 1999)
    2. Arfaptin 1, a putative cytosolic target protein of ADP-ribosylation factor, is recruited to Golgi membranes. (PubMed id 9038142)1, 2, 3 Kanoh H.... Exton J.H. (J. Biol. Chem. 1997)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Arfaptin 1 inhibits ADP-ribosylation factor-dependent matrix metalloproteinase-9 secretion induced by phorbol ester in HT 1080 fibrosarcoma cells. (PubMed id 12606037)1, 9 Ho W.T....Williger B.T. (FEBS Lett. 2003)
    6. Recruitment of arfaptins to the trans-Golgi network by PI(4)P and their involvement in cargo export. (PubMed id 23695357)1 Cruz-Garcia D....Malhotra V. (EMBO J. 2013)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    8. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    9. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 27236 HGNC: 21496 AceView: ARFIP1 Ensembl:ENSG00000164144 euGenes: HUgn27236
    ECgene: ARFIP1 H-InvDB: ARFIP1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for ARFIP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for ARFIP1 gene:
    Search GeneIP for patents involving ARFIP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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