ARFGAP3 Gene
protein-coding GIFtS: 54
GCID: GC22M043192
|
|
ADP-ribosylation factor GTPase activating protein 3(Previous name: ADP-ribosylation factor GTPase activating protein 1 )
(Previous symbol: ARFGAP1)
| |
Aliases
for ARFGAP3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| ADP-Ribosylation Factor GTPase Activating Protein 31 2 | | ARFGAP11 2 3 | | ADP-Ribosylation Factor GTPase Activating Protein 11 2 | | ARF GAP 32 3 | | ADP-Ribosylation Factor GTPase-Activating Protein 32 |
Export aliases for ARFGAP3 gene to outside databasesPrevious GC identifers: GC22M039795 GC22M041423 GC22M041517 GC22M026151 |
Summaries
for ARFGAP3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ARFGAP3:
The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus andregulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles.Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. Theactivity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms havebeen found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related butdifferent gene. (provided by RefSeq, Nov 2008)
UniProtKB/Swiss-Prot: ARFG3_HUMAN, Q9NP61Function: GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may leadto dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes
 summary
for ARFGAP3: Small G proteins (small GTPases) are homologous to G? proteins and are often referred to as the Ras
proto-oncogene superfamily. The Ras superfamily contains over 100 small GTPases grouped into eight families;
Ras, Rho, Rab, Rap, Arf, Ran, Rheb and Rad. Small GTPases regulate a wide variety of processes in the cell,
including growth, differentiation, movement and lipid vesicle transport. Like G? proteins, small GTPases
alternate between an 'on' state (bound to GTP) and an 'off' state (bound to GDP). This cyclic process
requires guanine nucleotide exchange factor (GEF) and GTPase-activating protein (GAP). Small GTPases are the
downstream effectors of most receptor tyrosine kinases (RTKs) and are linked via two proteins, GRB2 and SOS.
They are coupled to intracellular signaling cascades including the MAPK pathway, through interactions with
Raf kinase. Normally, activation of small GTPases is induced by ligand binding to a RTK. In many transformed
cells activating mutations of GTPases, often Ras, produce a cellular response in the absence of a ligand,
thus promoting malignant progression.
Gene Wiki entry for ARFGAP3
|
Genomic Views
for ARFGAP3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000022.10 NC_018933.1 NT_011520.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ARFGAP3 gene promoter:
Nkx3-1 Sp1 Nkx3-1 v1 CUTL1 LCR-F1 Nkx3-1 v2 PPAR-gamma1 FOXO4 PPAR-gamma2
Other transcription factors
Search SABiosciences Chromatin IP Primers for ARFGAP3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARFGAP3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q13.2 Ensembl cytogenetic band: 22q13.2 HGNC cytogenetic band: 22q13.2ARFGAP3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22M043192: view genomic region
(about GC identifiers)
Start:
|
43,192,508 bp from pter |
End:
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43,267,429 bp from pter |
Size:
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74,922 bases |
Orientation:
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minus strand |
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Proteins
for ARFGAP3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ARFG3_HUMAN, Q9NP61 (See
protein sequence)Recommended Name: ADP-ribosylation factor GTPase-activating protein 3 Size: 516 amino acids; 56928 Da
Subcellular location: Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Alsofound on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment
Developmental stage: Expressed at higher level in adult thymus, brain and lung, than in corresponding fetal tissues.Expressed at lower level in spleen, heart, kidney and liver during development
Caution: Was originally (PubMed:10704287) termed ARFGAP1
Sequence caution: Sequence=BAA92076.1; Type=Erroneous initiation; Sequence=BAB14236.1; Type=Erroneous initiation;
1 PDB 3D structure from  and Proteopedia  for ARFGAP3:2CRW (3D)
Secondary accessions: Q9BSC6 Q9H9J0 Q9NT10 Q9NUP5 Q9Y4V3 Q9Y4V4Explore the universe of human proteins at neXtProt for ARFGAP3: NX_Q9NP61
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NP61
ARFGAP3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001135765.1 NP_055385.3
ENSEMBL proteins: ENSP00000263245 ENSP00000388791 ENSP00000412510 ENSP00000413888 ENSP00000393079 ENSP00000412347 ENSP00000403995 ENSP00000403520 ENSP00000407734 ENSP00000393959
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
ARFGAP3 for ontologies About GeneDecksing
ARFGAP3 Antibody Products:
Assay Products for ARFGAP3: |
Protein
Domains /
Families
for ARFGAP3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ARFGAP3 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9NP61ProtoNet protein and cluster: Q9NP61 1 Blocks protein family: IPB001164 HIV Rev interacting protein signature
UniProtKB/Swiss-Prot: ARFG3_HUMAN, Q9NP61Similarity: Contains 1 Arf-GAP domain |
Function
for ARFGAP3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ARFG3_HUMAN, Q9NP61Function: GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may leadto dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranesEnzyme regulation: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARFGAP3 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARFGAP3 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ARFGAP3 (NM_014570) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ARFGAP3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARFGAP3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARFGAP3 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ARFGAP3 for ontologies About GeneDecksing
|
Pathways & Interactions
for ARFGAP3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | PAK Pathway | | | 2 | Endocytosis | | | 3 | GPCR Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for ARFGAP3
1 
Kegg Pathway (Kegg details for ARFGAP3):
ARFGAP3 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ARFGAP3
STRING Interaction
Network Preview (showing 5 interactants - click image to see 9)
5/10 Interacting proteins for ARFGAP3 (Q9NP613 ENSP000002632454) via UniProtKB, MINT, STRING, and/or I2D (see all 10)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
ARFGAP3 for ontologies About GeneDecksing
|
Drugs & Compounds
for ARFGAP3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ARFGAP3 for compounds About GeneDecksing
Compounds for ARFGAP3 available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| QS 11 | ARFGAP1 inhibitor; modulates Wnt/beta-catenin signaling | [944328-88-5] |
1 HMDB Compound for ARFGAP3 About this table
2 Novoseek chemical compound relationships for ARFGAP3 gene About this table
Search CenterWatch for drugs/clinical trials and news about ARFGAP3 / ARFG3
|
Transcripts
for ARFGAP3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ARFGAP3 gene (2 alternative transcripts): NM_001142293.1 NM_014570.4 Unigene Cluster for ARFGAP3: ADP-ribosylation factor GTPase activating protein 3 Hs.685225 [show with all ESTs]Unigene Representative Sequence: NM_01457011 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000263245(uc003bdd.2 uc010gzf.2 uc011apu.1) ENST00000437119
ENST00000452960 ENST00000453941 ENST00000456251 ENST00000440262 ENST00000453516
ENST00000454099 ENST00000435208 ENST00000493606 ENST00000429508
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARFGAP3 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARFGAP3 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ARFGAP3 (NM_014570) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ARFGAP3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARFGAP3 |
Additional cDNA sequence: AF111847.1 AK002083.1 AK022768.1 AK297635.1 AK300531.1 AK307967.1 AK315720.1 AL137598.1 AL159143.1 BC005122.2 CR456382.1 24 DOTS entries: DT.100845119 DT.416668 DT.100695965 DT.120646981 DT.120646873 DT.100753465 DT.100880812 DT.75103371 DT.91696140 DT.95205193 DT.120646988 DT.40254755 DT.92449515 DT.100680711 DT.100728446 DT.100772111 DT.100833676 DT.100880801 DT.100880820 DT.120646995 DT.120647121 DT.91864971 DT.95205198 DT.102838646 24/512 AceView cDNA sequences (see all 512): BM757646 BE047127 BM747236 AA397450 BQ921162 CA430748 CB158614 BM741184 AL389984 AI564351 CK430211 CR456536 BM758288 BM758980 AA911743 AI445097 AI401634 BM749809 BM748870 BQ921618 BM982147 AI023209 BM758473 BQ184379
GeneLoc Exon Structure
|
Expression
for ARFGAP3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ARFGAP3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGCTCAGGGC
About this image
See ARFGAP3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ARFGAP3
SOURCE GeneReport for Unigene cluster: Hs.685225
UniProtKB/Swiss-Prot: ARFG3_HUMAN, Q9NP61Tissue specificity: Widely expressed. Highest expression in endocrine glands (pancreas, pituitary gland, salivarygland, and prostate) and testis with a much higher expression in the testis than in the ovary
SABiosciences Custom PCR Arrays for ARFGAP3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ARFGAP3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ARFGAP3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARFGAP3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARFGAP3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARFGAP3 |
Orthologs
for ARFGAP3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ARFGAP3 gene from 9/29 species (see all 29) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ARFGAP31 |
ADP-ribosylation factor GTPase activating protein 3 |
71.11(n)
69.89(a) |
|
418224 NM_001012539.1 NP_001012557.1 |
lizard
(Anolis carolinensis) |
Reptilia |
ARFGAP36 |
-- |
72(a) |
1 ↔ 1 |
5(86931948-86976919) |
African clawed frog
(Xenopus laevis) |
Amphibia |
arfgap3-prov2 |
ADP-ribosylation factor GTPase activating protein 1 |
72.62(n) |
|
BC041750.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
arfgap36 |
ADP-ribosylation factor GTPase activating protein ... |
51(a) |
1 ↔ 1 |
4(62041878-62059140) |
fruit fly
(Drosophila melanogaster) |
Insecta |
ArfGAP36 |
ADP-ribosylation factor GTPase activating protein ... |
36(a) |
1 → many |
3L(22707413-22710677) |
worm
(Caenorhabditis elegans) |
Secernentea |
F07F6.46 |
Uncharacterized protein F07F6.4 |
33(a) |
1 → many |
II(5427432-5429557) |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
GLO31 |
Glo3p |
41.6(n)
32.01(a) |
|
856859 NP_011048.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AGD81 |
putative ADP-ribosylation factor GTPase-activating more |
46.23(n)
41.56(a) |
|
827512 NM_117898.4 NP_567543.1 |
rice
(Oryza sativa) |
Liliopsida |
Os10g05748001 |
hypothetical protein |
43.04(n)
32.85(a) |
|
4349482 NM_001072009.1 NP_001065477.1 |
ENSEMBL Gene Tree for ARFGAP3 (if available)
TreeFam Gene Tree for ARFGAP3 (if available) |
Paralogs
for ARFGAP3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ARFGAP3 gene
- ARFGAP22
18/25 SIMAP similar genes for ARFGAP3 using alignment to 6 protein entries: ARFG3_HUMAN (see all proteins)
(see all similar genes):ARFGAP2 ARFGAP1 SMAP1 DDEF2 ADAP1 ARAP3
ASAP1 CENTG2 AGAP1 AGAP2 CENTG3 DKFZp761E2216
AGAP3 FLJ00312 GIT1 AGAP11 AGAP8 ADAP2
ARFGAP3 for paralogs About GeneDecksing
|
Genomic Variants
for ARFGAP3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 22 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ARFGAP3 (43192508 - 43267429 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ARFGAP3
1 Indel: 103184 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ARFGAP3 |
|
Disorders
/ Diseases
for ARFGAP3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ARFGAP3 for disorders About GeneDecksing
OMIM gene information: 612439
OMIM disorders: --
2  diseases for ARFGAP3: About MalaCardsmalaria prostatitis
Human Genome Epidemiology (HuGE) Navigator: ARFGAP3 (1 document)
Export disorders for ARFGAP3 gene to outside databases
|
Publications
for ARFGAP3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ARFGAP3 gene, integrated from 9 sources (see all 34):
(articles sorted by number of sources associating them with ARFGAP3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Functional characterization of novel human ARFGAP3. (PubMed id 11172815)1, 2, 3, 9 Liu X.... He F. (2001)
- Characterization, chromosomal assignment, and tissue expression of a novel human gene belonging to the ARF GAP family. (PubMed id 10704287)1, 2, 3, 9 Zhang C.... He F. (2000)
- Two human ARFGAPs associated with COP-I-coated vesicles. (PubMed id 17760859)1, 2 Frigerio G.... Duden R. (2007)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (2004)
- Reevaluating human gene annotation: a second-generation analysis of chromosome 22. (PubMed id 12529303)1, 2 Collins J.E.... Dunham I. (2003)
- The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I....O'Brien K.P. (1999)
- Differential roles of ArfGAP1, ArfGAP2, and ArfGAP3 in COPI trafficking. (PubMed id 19015319)1, 9 Weimer C....Wieland F. (2008)
- ARFGAP3, an androgen target gene, promotes prostate ca ncer cell proliferation and migration. (PubMed id 21647875)1 Obinata D....Inoue S. (2012)
|
External Searches for ARFGAP3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ARFGAP3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ARFGAP3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ARFGAP3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ARFGAP3 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ARFGAP3 gene:
Search GeneIP for patents involving ARFGAP3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ARFGAP3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for ARFGAP3 | | OriGene shRNA RFP for ARFGAP3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ARFGAP3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ARFGAP3 | | | OriGene Protein Over-expression Lysate for ARFGAP3 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ARFGAP3 | | OriGene 3'-UTR Clone for ARFGAP3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARFGAP3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARFGAP3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ARFGAP3 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ARFGAP3 | | OriGene Custom Protein Services for ARFGAP3 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ARFGAP3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ARFGAP3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARFGAP3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ARFGAP3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARFGAP3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARFGAP3 |
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 | | | ARFGAP3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARFGAP3 |
|  |  |  | | | | ThermoFisher Antibodies for ARFGAP3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARFGAP3 |
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