Aliases for ARF4 Gene
Aliases for ARF4 Gene
External Ids for ARF4 Gene
- HGNC: 655
- Entrez Gene: 378
- Ensembl: ENSG00000168374
- OMIM: 601177
- UniProtKB: P18085
Previous HGNC Symbols for ARF4 Gene
- ARF2
Previous GeneCards Identifiers for ARF4 Gene
- GC03M056428
- GC03M056911
- GC03M057411
- GC03M057514
- GC03M057507
- GC03M057532
Summaries for ARF4 Gene
-
This gene is a member of the human ARF gene family whose members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 5 ARF proteins and 11 ARF-like proteins and constitute one family of the RAS superfamily. The ARF proteins are categorized as class I, class II and class III; this gene is a class II member. The members of each class share a common gene organization. The ARF4 gene spans approximately 12kb and contains six exons and five introns. This gene is the most divergent member of the human ARFs. Conflicting map positions at 3p14 or 3p21 have been reported for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for ARF4 Gene
ARF4 (ADP Ribosylation Factor 4) is a Protein Coding gene. Diseases associated with ARF4 include Cholera. Among its related pathways are Cargo trafficking to the periciliary membrane and Vesicle-mediated transport. GO annotations related to this gene include GTP binding and signal transducer activity. An important paralog of this gene is ARF5.
UniProtKB/Swiss-Prot for ARF4 Gene
-
GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARF4 Gene
Genomics for ARF4 Gene
Regulatory Elements for ARF4 Gene
Regulatory Element Products
Genomic Location for ARF4 Gene
- Chromosome:
- 3
- Start:
- 57,571,363 bp from pter
- End:
- 57,598,220 bp from pter
- Size:
- 26,858 bases
- Orientation:
- Minus strand
Genomic View for ARF4 Gene
- Cytogenetic band:
-
- 3p14.3 by Ensembl
- 3p14.3 by Entrez Gene
- 3p14.3 by HGNC
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ARF4 Gene
Proteins for ARF4 Gene
-
Protein details for ARF4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P18085-ARF4_HUMAN
- Recommended name:
- ADP-ribosylation factor 4
- Protein Accession:
- P18085
- B2R7J7
- P21371
Protein attributes for ARF4 Gene
- Size:
- 180 amino acids
- Molecular mass:
- 20511 Da
- Quaternary structure:
- No Data Available
Protein Expression for ARF4 Gene
Post-translational modifications for ARF4 Gene
Other Protein References for ARF4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for ARF4
- Invitrogen Antibodies for ARF4
- antibodies-online Antibodies for ARF4: See all 65
- GeneTex ARF4 antibody for ARF4
-
Santa Cruz Biotechnology (SCBT) Antibodies for ARF4
Protein Products
-
OriGene Purified Proteins for ARF4
- Search Origene for MassSpec and Protein Over-expression Lysates for ARF4
- Origene Custom Protein Services for ARF4
- ProSpec Recombinant Proteins for ARF4
- antibodies-online Proteins for ARF4: See all 21
- Search antibodies-online for peptides
- Search GeneTex for Proteins for ARF4
Assay Products
- antibodies-online Kits for ARF4: See all 18
No data available for DME Specific Peptides for ARF4 Gene
Domains & Families for ARF4 Gene
Gene Families for ARF4 Gene
- HGNC:
Protein Domains for ARF4 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ARF4 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P18085- Family:
-
- Belongs to the small GTPase superfamily. Arf family.
Function for ARF4 Gene
Molecular function for ARF4 Gene
- GENATLAS Biochemistry:
- ADP ribosylation factor 4,class II,20kDa,low molecular weight GTP binding protein,a guanine nucleotide dependent protein activator of cholera toxin,widely expressed,except in brain,involved in vesicular trafficking and activation of phospholipase D
- UniProtKB/Swiss-Prot Function:
- GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003924 | GTPase activity | TAS | -- |
| GO:0005086 | ARF guanyl-nucleotide exchange factor activity | TAS | -- |
| GO:0005154 | epidermal growth factor receptor binding | IDA | 12446727 |
| GO:0005515 | protein binding | IPI | 17956946 |
| GO:0005525 | GTP binding | IEA,IDA | 12446727 |
Phenotypes for ARF4 Gene
- MGI mutant phenotypes for ARF4:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for ARF4:
-
- Increased vaccinia virus (VACV) infection
- shRNA abundance <= 50%
- Synthetic lethal with Ras
- Mildly decreased CFP-tsO45G cell surface transport
- Lamellipodia cells
- Increased shRNA abundance (Z-score > 2)
- Decreased shRNA abundance (Z-score < -2)
- Increased G1 DNA content
- G0/1 arrest
- Increased cilium length after serum starvation
- Decreased viability
- Decreased viability with SS1P at EC30
Animal Models for ARF4 Gene
- MGI Knock Outs for ARF4:
-
- Arf4 tm1b(KOMP)Wtsi
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ARF4
-
-
ViGene Biosciences lentiviral particle packaged cDNA for ARF4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ARF4 gene
- Search ViGene Biosciences for ARF4
CRISPR Products
-
OriGene CRISPR knockouts for ARF4
-
Santa Cruz Biotechnology (SCBT) CRISPR for ARF4
- GenScript: Design CRISPR guide RNA sequences for ARF4
miRNA for ARF4 Gene
- miRTarBase miRNAs that target ARF4
miRNA Products
- Search ViGene Biosciences for ARF4
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ARF4
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-
ViGene Biosciences ready-to-package AAV shRNAs for ARF4 gene
Clone Products
- Sino Biological Human cDNA Clone for ARF4
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- Addgene plasmids for ARF4
- VectorBuilder custom plasmid, inducible vectors for ARF4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ARF4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for ARF4
-
ViGene Biosciences adenoviral particle packaged cDNA for ARF4 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ARF4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ARF4 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ARF4 Gene
Localization for ARF4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ARF4 Gene
- Golgi apparatus. Membrane; Lipid-anchor.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005622 | intracellular | IEA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005794 | Golgi apparatus | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0005886 | plasma membrane | IEA | -- |
Pathways & Interactions for ARF4 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Transport to the Golgi and subsequent modification | ||
| 2 | Golgi-to-ER retrograde transport | ||
| 3 | Cargo trafficking to the periciliary membrane | ||
| 4 | Organelle biogenesis and maintenance |
.56
|
|
| 5 | Vesicle-mediated transport | ||
Pathways by source for ARF4 Gene
1 BioSystems pathway for ARF4 Gene
2 Qiagen pathways for ARF4 Gene
Interacting Proteins for ARF4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006471 | protein ADP-ribosylation | IDA | 1899243 |
| GO:0006810 | transport | IEA | -- |
| GO:0006888 | ER to Golgi vesicle-mediated transport | TAS | -- |
| GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER | TAS | -- |
| GO:0007173 | epidermal growth factor receptor signaling pathway | IEA | -- |
No data available for SIGNOR curated interactions for ARF4 Gene
Transcripts for ARF4 Gene
mRNA/cDNA for ARF4 Gene
- (1234) Selected AceView cDNA sequences:
- (7) Additional mRNA sequences :
- (1) REFSEQ mRNAs :
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ARF4 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ARF4
-
Santa Cruz Biotechnology (SCBT) CRISPR for ARF4
- GenScript: Design CRISPR guide RNA sequences for ARF4
miRNA Products
- Search ViGene Biosciences for ARF4
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ARF4
- Browse OriGene Inhibitory RNA Products For ARF4
-
ViGene Biosciences ready-to-package AAV shRNAs for ARF4 gene
Clone Products
- Sino Biological Human cDNA Clone for ARF4
- Sino Biological Human cDNA Clone for ARF4
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for ARF4
- VectorBuilder custom plasmid, inducible vectors for ARF4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ARF4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | · | 5d | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | · | 8d |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||
| SP6: | - | ||||||||||||||||||||||||||||||||||||||
| SP7: |
Expression for ARF4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Neural Tube (Nervous System)
- Floor Plate Cells Spinal Floor Plate
- Spinal Ventral Columns
- Spinal Floor Plate
- Metencephalon
-
Skeletal Muscle (Muscoskeletal System)
- Mononuclear Myocytes Hyoid Arch Muscles
- Mononuclear Myocytes Mandibular Arch Muscles
- Bone (Muscoskeletal System)
- Cartilage (Muscoskeletal System)
- Brain (Nervous System)
- Gut Tube (Gastrointestinal Tract)
- Limb (Muscoskeletal System)
-
Larynx (Respiratory System)
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ARF4 Gene
NURSA nuclear receptor signaling pathways regulating expression of ARF4 Gene:
ARF4SOURCE GeneReport for Unigene cluster for ARF4 Gene:
Hs.652183Evidence on tissue expression from TISSUES for ARF4 Gene
- Nervous system(4.9)
- Skin(4.8)
- Liver(4.4)
- Bone marrow(4.3)
- Lung(4.1)
- Intestine(3.4)
- Kidney(3.3)
- Pancreas(3.3)
- Stomach(2.7)
- Blood(2.4)
- Gall bladder(2.1)
- Adrenal gland(2)
- Heart(2)
- Spleen(2)
- Thyroid gland(2)
Primer Products
-
OriGene qPCR primer pairs for ARF4
-
OriGene qPCR primer pairs and template standards for ARF4
No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ARF4 Gene
Orthologs for ARF4 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ARF4 35 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | ARF4 35 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | ARF4 35 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | ARF4 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Arf4 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Arf4 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | ARF4 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ARF4 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | ARF4 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | arf4 34 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | LOC398551 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | arf4a 34 35 |
|
||
| ARF4 (3 of 3) 35 |
|
OneToMany | |||
| ARF4 (2 of 3) 35 |
|
OneToMany | |||
| fruit fly (Drosophila melanogaster) |
Insecta | Arf79F 36 |
|
|
|
| Arf102F 36 34 35 |
|
||||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP002931 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | arf-3 36 35 |
|
||
| arf-1 36 |
|
|
|||
| arl-6 36 |
|
|
|||
| arl-5 36 |
|
|
|||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | ARF1 35 |
|
ManyToMany | |
| ARF2 35 |
|
ManyToMany | |||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToMany |
- Species where no ortholog for ARF4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for ARF4 Gene
Paralogs for ARF4 Gene
(31) SIMAP similar genes for ARF4 Gene using alignment to 6 proteins:
Pseudogenes.org Pseudogenes for ARF4 Gene
Variants for ARF4 Gene
| SNP ID | Clin | Chr 03 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000012709 | -- | 57,590,290(+) | GACCA(A/G)CCTGG | intron-variant | |
| rs1000042127 | -- | 57,578,636(+) | CACCA(C/T)ACCTA | intron-variant | |
| rs1000101374 | -- | 57,572,123(+) | ATACT(A/G)TTTAA | intron-variant, utr-variant-3-prime | |
| rs1000132113 | -- | 57,591,927(+) | CTAAT(G/T)GGTAT | intron-variant | |
| rs1000178729 | -- | 57,596,438(+) | GTTTT(C/T)GGAGA | intron-variant, upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1008684 | CNV | gain | 25217958 |
| nsv590368 | CNV | gain | 21841781 |
Relevant External Links for ARF4 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ARF4 Gene
Disorders for ARF4 Gene
Relevant External Links for ARF4
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- ARF4
No data available for UniProtKB/Swiss-Prot and Genatlas for ARF4 Gene
Publications for ARF4 Gene
- Cloning and characterization of the human ADP-ribosylation factor 4 gene. (PMID: 10524252) Lebeda R.A. … Haun R.S. (Gene 1999) 3 4 22 64
- Selective amplification of an mRNA and related pseudogene for a human ADP-ribosylation factor, a guanine nucleotide-dependent protein activator of cholera toxin. (PMID: 2107548) Monaco L. … Vaughan M. (Proc. Natl. Acad. Sci. U.S.A. 1990) 2 3 4 64
- Identification of ADP-ribosylation factor 4 as a suppressor of N-(4-hydroxyphenyl)retinamide-induced cell death. (PMID: 19041174) Woo I.S. … Seo H.G. (Cancer Lett. 2009) 3 22 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- Human ADP-ribosylation factor 4 (ARF4) gene. Map position 3p14.1. (PMID: 10099884) Kim H.S. (Chromosome Res. 1998) 3 22 64
Products for ARF4 Gene
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- GenScript: Design CRISPR guide RNA sequences for ARF4
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- Novus Biologicals Antibodies for ARF4
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- Novus Biologicals
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- ProSpec Recombinant Proteins for ARF4
- Addgene plasmids for ARF4
- antibodies-online Antibodies for ARF4: See all 65
- antibodies-online Kits for ARF4: See all 18
- antibodies-online Proteins for ARF4: See all 21
- Search antibodies-online for peptides
- GeneTex ARF4 antibody for ARF4
- Search GeneTex for Proteins for ARF4
- ViGene Biosciences adenoviral particle packaged cDNA for ARF4 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ARF4 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ARF4 gene
- Search ViGene Biosciences for ARF4
- Santa Cruz Biotechnology (SCBT) Antibodies for ARF4
- Search Santa Cruz Biotechnology (SCBT) for ARF4 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ARF4
- Horizon Cell Lines for ARF4
- Cyagen custom Knockout/knockin (KOKI) mouse models for ARF4
- VectorBuilder custom plasmid, inducible vectors for ARF4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ARF4
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ARF4 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
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