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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ARF3 Gene

protein-coding   GIFtS: 62
GCID: GC12M049299

ADP-ribosylation factor 3

 Explore 12 diseases affiliated with
ARF3 via our new
 Human Malady Compendium 
Biological research products
for ARF3
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
ADP-Ribosylation Factor 31 2
Small GTP Binding Protein2

External Ids:    HGNC: 6541   Entrez Gene: 3772   Ensembl: ENSG000001342877   OMIM: 1031905   UniProtKB: P612043   

Export aliases for ARF3 gene to outside databases

Previous GC identifers: GC12M049256 GC12M049556 GC12M049046 GC12M047616 GC12M049329 GC12M046361


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ARF3:
ADP-ribosylation factor 3 (ARF3) is a member of the human ARF gene family. These genes encode small guanine
nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in
vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like
proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and
ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization. The
ARF3 gene contains five exons and four introns. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: ARF3_HUMAN, P61204
Function: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an
ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi
apparatus

Gene Wiki entry for ARF3


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.1  NT_029419.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ARF3 gene promoter:
         SREBP-1c   E2F-2   HNF-4alpha2   HNF-4alpha1   SREBP-1b   SREBP-1a   E2F-1   E2F   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidARF3 promoter sequence
   Search SABiosciences Chromatin IP Primers for ARF3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARF3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13   Ensembl cytogenetic band:  12q13.12   HGNC cytogenetic band: 12q13.12

ARF3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARF3 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M049299:  view genomic region     (about GC identifiers)

Start:
49,297,286 bp from pter      End:
49,351,334 bp from pter
Size:
54,049 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ARF3_HUMAN, P61204 (See protein sequence)
Recommended Name: ADP-ribosylation factor 3  
Size: 181 amino acids; 20601 Da
Subunit: Interacts with PRKCABP. Interacts with PI4KB and NCS1/FREQ at the Golgi complex
Subcellular location: Golgi apparatus. Cytoplasm, perinuclear region
Secondary accessions: A8K6G8 P16587

Explore the universe of human proteins at neXtProt for ARF3: NX_P61204

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P61204

  • ARF3 Protein expression data from MOPED and PaxDb:    About this image 
    ARF3 Protein Expression
    REFSEQ proteins: NP_001650.1  
    ENSEMBL proteins: 
     ENSP00000438507   ENSP00000256682   ENSP00000395370   ENSP00000438510   ENSP00000438063  
     ENSP00000437374   ENSP00000446353  
    Reactome Protein details: P61204
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    Uscn Proteins for ARF3

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane TAS--
    GO:0005622intracellular ----
    GO:0005794Golgi apparatus ----
    GO:0048471perinuclear region of cytoplasm IEA--

    ARF3 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ARF3 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR006689 Small_GTPase_ARF/SAR
     IPR024156 Small_GTPase_ARF
     IPR005225 Small_GTP-bd_dom

    Graphical View of Domain Structure for InterPro Entry P61204

    ProtoNet protein and cluster: P61204

    UniProtKB/Swiss-Prot: ARF3_HUMAN, P61204
    Similarity: Belongs to the small GTPase superfamily. Arf family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ARF3_HUMAN, P61204
    Function: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an
    ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi
    apparatus

         Genatlas biochemistry entry for ARF3:
    ADP ribosylation factor 3,class I,low molecular weight GTP binding protein,a guanine nucleotide dependent protein
    activator of cholera toxin,with two transcripts resulting from alternative use of polyadenylation
    transcripts,(20kDa),widely expressed,especially in brain,Ras superfamily member,involved in vesicular trafficking and
    activation of phospholipase D

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity TAS1744102
    GO:0005525GTP binding IEA--
         
    ARF3 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ARF3:
     Upregulation of Wnt/beta-caten 

    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/6 super-pathways (see all 6About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Metabolism
    Metabolism1.00
    Metabolism of lipids and lipoproteins0.34
    2PI Metabolism
    PI Metabolism1.00
    3Glycerophospholipid biosynthesis
    Phospholipid metabolism0.64
    4GPCR Pathway
    Paxillin Interactions0.53
    5Neuropathic Pain-Signaling in Dorsal Horn Neurons
    Cholera Infection0.40

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for ARF3
        Cholera Infection
    Paxillin Interactions

    5        Reactome Pathways for ARF3
        Metabolism
    Phospholipid metabolism
    Metabolism of lipids and lipoproteins
    PI Metabolism
    Synthesis of PIPs at the Golgi membrane



    ARF3 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ARF3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/15 Interacting proteins for ARF3 (P612043 ENSP000002566824) via UniProtKB, MINT, STRING, and/or I2D (see all 15)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARFIP2P533653, ENSP000002545844I2D: score=3 STRING: ENSP00000254584
    ARFIP1P533673, ENSP000002965574I2D: score=2 STRING: ENSP00000296557
    KIF23Q022413, ENSP000002603634I2D: score=2 STRING: ENSP00000260363
    GGA1Q9UJY53, ENSP000003413444I2D: score=1 STRING: ENSP00000341344
    GGA3Q9NZ523, ENSP000002455414I2D: score=1 STRING: ENSP00000245541
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006184GTP catabolic process TAS1744102
    GO:0006644phospholipid metabolic process TAS--
    GO:0006661phosphatidylinositol biosynthetic process TAS--
    GO:0007264small GTPase mediated signal transduction IEA--
    GO:0015031protein transport IEA--

    ARF3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    ARF3 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for ARF3

    1 HMDB Compound for ARF3    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--
    4 Novoseek chemical compound relationships for ARF3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    gdp 62.4 5 11150519 (2), 9050849 (1), 17227842 (1)
    gtp 58.3 2 8290961 (1), 17227842 (1)
    lipoteichoic acid 56.1 1 15064466 (1)
    lipid 0 1 7575443 (1)

    Search CenterWatch for drugs/clinical trials and news about ARF3 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ARF3 gene: 
    NM_001659.2  

    Unigene Cluster for ARF3:

    ADP-ribosylation factor 3
    Hs.119177  [show with all ESTs]
    Unigene Representative Sequence: M74491
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000398092 ENST00000256682(uc001rsr.2 uc010smc.1) ENST00000485410
    ENST00000447318 ENST00000541959 ENST00000541236 ENST00000539611 ENST00000545855
    ENST00000541967 ENST00000472621 ENST00000536283

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    hsa-miR-21* hsa-miR-3130-5p hsa-miR-513a-5p hsa-miR-128 hsa-miR-4330 hsa-miR-509-3-5p hsa-miR-324-5p hsa-miR-181b
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    Additional cDNA sequence: 

    AF493882.1 AK291633.1 AK300080.1 AK303726.1 AK309899.1 AK315970.1 AK316528.1 BC007647.1 
    BC007762.2 BC017565.2 BC028402.2 BT006670.1 M74491.1 

    24/32 DOTS entries (see all 32):

    DT.92403904  DT.75113000  DT.100826563  DT.219676  DT.95087025  DT.100826559  DT.75135167  DT.100045064 
    DT.100045065  DT.121151631  DT.92455636  DT.97799479  DT.100826557  DT.121151576  DT.92455631  DT.95342211 
    DT.100826560  DT.121151541  DT.121151584  DT.121151612  DT.121151617  DT.121151629  DT.121151640  DT.95189350 

    10 AceView cDNA sequences:

    CR607986 BC007762 BC017565 M74491 BT006670 BC007647 BC028402 AF493882 
    NM_001659 M33384 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for ARF3 (see all 10)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b · 4c · 4d · 4e · 4f ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11a · 11b · 11c
    SP1:                                -     -     -     -     -     -     -     -     -                                                                     
    SP2:                                -     -     -     -     -     -     -     -     -                 -     -                                             
    SP3:                                -     -     -     -     -     -     -     -     -                       -     -                                       
    SP4:                                -     -     -     -     -                 -                                                                           
    SP5:                                      -     -     -                       -     -                                                                     


    ECgene alternative splicing isoforms for ARF3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ARF3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AGGACTTTGC
    ARF3 Expression
    About this image
    See ARF3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ARF3

    SOURCE GeneReport for Unigene cluster: Hs.119177
        SABiosciences Custom PCR Arrays for ARF3

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ARF3 gene from 7/30 species (see all 30)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    lizard
    (Anolis carolinensis)
    Reptilia ARF36
    --
    100(a)
    1 ↔ 1
    2(94135780-94145286)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.65392 Xenopus laevis transcribed sequence with strong similarity more 83.57(n)    BU914466.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BC050487.12   -- 83.07(n)    BC050487.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Arf79F3 protein amino acid ADP-ribosylation GTP
    binding
    94(a)
    (best of 2)
      80B2   --
    worm
    (Caenorhabditis elegans)
    Secernentea arf-13 ARF 92(a)
    (best of 5)
      III(5787540-5788738)   --
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons ATARFA1E6
    ATARF16
    (see all 6)
    ADP-ribosylation factor 2
    (see all 6)
    88(a)
    87(a)
    (see all 6)
    many ↔ many
    many ↔ many
    (see all 6)
    3(23051544-23053817)
    1(8336683-8338672)
    rice
    (Oryza sativa)
    Liliopsida AK105508.12   -- 81.43(n)    AK105508.1 


    ENSEMBL Gene Tree for ARF3 (if available)
    TreeFam Gene Tree for ARF3 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ARF3 gene
    ARL4A2  ARL112  ARF42  ARF52  ARF12  ARL4D2  ARL142  ARF62  
    ARL92  ARL17B2  ARL4C2  TRIM232  ARL102  
    18/40 SIMAP similar genes for ARF3 using alignment to 6 protein entries:     ARF3_HUMAN (see all proteins) (see all similar genes):
    ARF1    ARL17B    ARL17A    FKBP3    ARF4    TCEB1
    ARF5    ARL1    ARF6    TRIM23    ARL14    SHANK2
    UTY    ARL4D    ARL2    ARL11    DKFZp434B2017    ARL4A

    ARF3 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for ARF3
    PGOHUM00000248484 PGOHUM00000259233


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/382 NCBI SNPs in ARF3 are shown (see all 382    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs797446991,2
    C--49329509(+) CAGACG/ATTTAT 1 -- ds50012Minor allele frequency- A:0.08NA 122
    rs171233981,2
    C,F,H--49329527(+) GTTTAT/CTCACT 1 -- ds50018Minor allele frequency- C:0.05NA NS EA WA 668
    rs1497393861,2
    C--49329557(+) AGTGA-/GGGGGG 1 -- ds50010--------
    rs1810970401,2
    --49329563(+) AGGGGA/GTCTCT 1 -- ds50010--------
    rs1140752871,2
    F--49329609(+) GAGATC/TTGAGA 1 -- ds50011Minor allele frequency- T:0.07WA 118
    rs22723111,2
    C,F,A,H--49329695(+) AATACA/GGCTGA 1 -- ds500121Minor allele frequency- G:0.38EA NS NA CSA WA 3832
    rs795237991,2
    F--49329907(+) GGAGAG/AAGGGA 1 -- ds50011Minor allele frequency- A:0.13WA 118
    rs577287081,2
    --49329954(+) CCCACG/AGCTGC 1 -- ds50012Minor allele frequency- A:0.11CSA WA 120
    rs1868458761,2
    --49330124(+) CCACTA/GTAACA 1 -- ut310--------
    rs412919731,2
    --49330151(+) GGGTGC/GGGGGA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for ARF3 (49297286 - 49351334 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for ARF3
         1 CNV: 4777

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ARF3 for disorders           About GeneDecksing

    OMIM gene information: 103190    OMIM disorders: --

    12 diseases for ARF3:    About MalaCards
    distal hereditary motor neuropathy    distal hereditary motor neuropathy, type ii    cholera    platelet storage pool deficiency
    chronic lymphocytic leukemia    lymphocytic leukemia    neuropathy    gout
    gastric cancer    leukemia    ataxia    malaria

    2 diseases from the University of Copenhagen DISEASES database for ARF3:
    Platelet storage pool deficiency     Cholera

    1 Novoseek disease relationship for ARF3 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cholera 53.9 1 1744102 (1)

    Human Genome Epidemiology (HuGE) Navigator: ARF3 (3 documents)

    Export disorders for ARF3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ARF3 gene, integrated from 9 sources (see all 70):
    (articles sorted by number of sources associating them with ARF3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Assignment of human ADP ribosylation factor (ARF) genes ARF1 and ARF3 to chromosomes 1q42 and 12q13, respectively. (PubMed id 8661066)1, 3, 9 Hirai M....Hashimoto K. (1996)
    2. Isolation and characterization of the human gene for ADP-ribosylation factor 3, a 20-kDa guanine nucleotide-binding protein activator of cholera toxin. (PubMed id 1744102)1, 2, 9 Tsai S.C.... Vaughan M. (1991)
    3. Interaction of the PDZ domain of human PICK1 with class I ADP- ribosylation factors. (PubMed id 10623590)1, 2, 9 Takeya R.... Sumimoto H. (2000)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Molecular cloning, characterization, and expression of human ADP- ribosylation factors: two guanine nucleotide-dependent activators of cholera toxin. (PubMed id 2474826)1, 2 Bobak D.A....Vaughan M. (1989)
    6. Characterization of the human ADP-ribosylation factor 3 promoter. Transcriptional regulation of a TATA-less promoter. (PubMed id 8473323)1, 9 Haun R.S....Vaughan M. (1993)
    7. A family of ADP-ribosylation factor effectors that can alter transport through the trans-Golgi. (PubMed id 10749927)1, 9 Boman A.L.... Kahn R.A. (2000)
    8. Arfaptin 1 forms a complex with ADP-ribosylation factor and inhibits phospholipase D. (PubMed id 10413101)1, 9 Williger B.-T.... Exton J.H. (1999)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    10. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 377 HGNC: 654 AceView: ARF3 Ensembl:ENSG00000134287 euGenes: HUgn377
    ECgene: ARF3 H-InvDB: ARF3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ARF3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ARF3 gene:
    Search GeneIP for patents involving ARF3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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