Aliases for AREL1 Gene
Aliases for AREL1 Gene
External Ids for AREL1 Gene
- HGNC: 20363
- Entrez Gene: 9870
- Ensembl: ENSG00000119682
- OMIM: 615380
- UniProtKB: O15033
Previous HGNC Symbols for AREL1 Gene
- KIAA0317
Previous GeneCards Identifiers for AREL1 Gene
- GC14M075120
Summaries for AREL1 Gene
GeneCards Summary for AREL1 Gene
AREL1 (Apoptosis Resistant E3 Ubiquitin Protein Ligase 1) is a Protein Coding gene. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. GO annotations related to this gene include ligase activity and ubiquitin-protein transferase activity. An important paralog of this gene is NEDD4L.
UniProtKB/Swiss-Prot for AREL1 Gene
-
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits apoptosis by ubiquitinating and targeting for degradation a number of proapoptotic proteins including DIABLO/SMAC, HTRA2 and SEPT4/ARTS which are released from the mitochondrion into the cytosol following apoptotic stimulation.
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AREL1 Gene
Genomics for AREL1 Gene
Regulatory Elements for AREL1 Gene
Enhancers for AREL1 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around AREL1 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for AREL1 Gene
- Chromosome:
- 14
- Start:
- 74,653,437 bp from pter
- End:
- 74,713,115 bp from pter
- Size:
- 59,679 bases
- Orientation:
- Minus strand
Genomic View for AREL1 Gene
Genes around AREL1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 14q24.3 by Ensembl
- 14q24.3 by Entrez Gene
- 14q24.3 by HGNC
AREL1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for AREL1 Gene
Proteins for AREL1 Gene
-
Protein details for AREL1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O15033-AREL1_HUMAN
- Recommended name:
- Apoptosis-resistant E3 ubiquitin protein ligase 1
- Protein Accession:
- O15033
- B4E2C7
- Q7LDY1
- Q8IYY9
Protein attributes for AREL1 Gene
- Size:
- 823 amino acids
- Molecular mass:
- 94223 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAA20775.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
Protein Expression for AREL1 Gene
Post-translational modifications for AREL1 Gene
- Autoubiquitinated in vitro in the presence of E2 enzyme UBE2D1/UBCH5A.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for AREL1 Gene
Antibody Products
- Novus Biologicals Antibodies for AREL1
- Invitrogen Antibodies for AREL1
- GeneTex AREL1 antibody for AREL1
Protein Products
-
OriGene Purified Proteins for AREL1
- Search Origene for MassSpec and Protein Over-expression Lysates for AREL1
- Origene Custom Protein Services for AREL1
- Search GeneTex for Proteins for AREL1
Assay Products
No data available for DME Specific Peptides for AREL1 Gene
Domains & Families for AREL1 Gene
Protein Domains for AREL1 Gene
Suggested Antigen Peptide Sequences for AREL1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families and UniProtKB/Swiss-Prot for AREL1 Gene
Function for AREL1 Gene
Molecular function for AREL1 Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.
- UniProtKB/Swiss-Prot Function:
- E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits apoptosis by ubiquitinating and targeting for degradation a number of proapoptotic proteins including DIABLO/SMAC, HTRA2 and SEPT4/ARTS which are released from the mitochondrion into the cytosol following apoptotic stimulation.
Enzyme Numbers (IUBMB) for AREL1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004842 | ubiquitin-protein transferase activity | IDA | 23479728 |
| GO:0016740 | transferase activity | IEA | -- |
Phenotypes for AREL1 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for AREL1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for AREL1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for AREL1 gene
- Search ViGene Biosciences for AREL1
CRISPR Products
-
OriGene CRISPR knockouts for AREL1
-
Santa Cruz Biotechnology (SCBT) CRISPR for AREL1
- GenScript: Design CRISPR guide RNA sequences for AREL1
miRNA for AREL1 Gene
- miRTarBase miRNAs that target AREL1
-
- hsa-mir-548b-3p (MIRT016243)
- hsa-mir-193b-3p (MIRT016609)
- hsa-mir-148b-5p (MIRT280158)
- hsa-mir-3168 (MIRT280161)
- hsa-mir-5584-3p (MIRT280164)
- hsa-mir-6874-3p (MIRT280165)
- hsa-mir-1470 (MIRT280167)
- hsa-mir-4667-3p (MIRT380488)
- hsa-mir-135b-3p (MIRT481638)
- hsa-mir-6800-5p (MIRT481639)
- hsa-mir-1294 (MIRT481640)
- hsa-mir-4504 (MIRT481641)
- hsa-mir-6081 (MIRT481642)
- hsa-mir-4710 (MIRT481643)
- hsa-mir-3665 (MIRT481644)
- hsa-mir-202-3p (MIRT481645)
- hsa-mir-98-5p (MIRT481646)
- hsa-mir-4500 (MIRT481647)
- hsa-mir-4458 (MIRT481648)
- hsa-let-7i-5p (MIRT481649)
- hsa-let-7g-5p (MIRT481650)
- hsa-let-7f-5p (MIRT481651)
- hsa-let-7e-5p (MIRT481652)
- hsa-let-7d-5p (MIRT481653)
- hsa-let-7c-5p (MIRT481654)
- hsa-let-7b-5p (MIRT481655)
- hsa-let-7a-5p (MIRT481656)
- hsa-mir-125a-3p (MIRT481657)
- hsa-mir-192-3p (MIRT495102)
- hsa-mir-1256 (MIRT495103)
- hsa-mir-4317 (MIRT495104)
- hsa-mir-4459 (MIRT495105)
- hsa-mir-4695-5p (MIRT495106)
- hsa-mir-6507-3p (MIRT495107)
- hsa-mir-3910 (MIRT495108)
- hsa-mir-302c-5p (MIRT539146)
- hsa-mir-519e-3p (MIRT539147)
- hsa-mir-515-3p (MIRT539148)
- hsa-mir-33b-3p (MIRT539149)
- hsa-mir-371a-3p (MIRT539150)
- hsa-mir-371b-3p (MIRT539151)
- hsa-mir-7-2-3p (MIRT539152)
- hsa-mir-7-1-3p (MIRT539153)
- hsa-mir-5688 (MIRT539154)
- hsa-mir-495-3p (MIRT539155)
- hsa-mir-497-3p (MIRT539156)
- hsa-mir-6749-3p (MIRT626030)
- hsa-mir-6792-3p (MIRT626031)
- hsa-mir-4691-5p (MIRT626032)
- hsa-mir-7162-5p (MIRT626033)
- hsa-mir-516b-3p (MIRT626034)
- hsa-mir-516a-3p (MIRT626035)
- hsa-mir-4469 (MIRT626036)
- hsa-mir-100-3p (MIRT626037)
- hsa-mir-4279 (MIRT660557)
- hsa-mir-1200 (MIRT660558)
- hsa-mir-378a-5p (MIRT660559)
- hsa-mir-3667-3p (MIRT660560)
- hsa-mir-6734-3p (MIRT660561)
miRNA Products
- Search ViGene Biosciences for AREL1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for AREL1
- Browse OriGene Inhibitory RNA Products For AREL1
-
ViGene Biosciences ready-to-package AAV shRNAs for AREL1 gene
Clone Products
-
OriGene ORF clones in human for AREL1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for AREL1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AREL1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for AREL1
-
ViGene Biosciences adenoviral particle packaged cDNA for AREL1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for AREL1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for AREL1 gene
Flow Cytometry Products
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for AREL1 Gene
Localization for AREL1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for AREL1 Gene
- Cytoplasm, cytosol.
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| endoplasmic reticulum | 3 |
| nucleus | 2 |
| mitochondrion | 1 |
| peroxisome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | IDA,IEA | 23479728 |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for AREL1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Class I MHC mediated antigen processing and presentation | ||
| 2 | Innate Immune System |
.61
|
|
Pathways by source for AREL1 Gene
4 Reactome pathways for AREL1 Gene
UniProtKB/Swiss-Prot O15033-AREL1_HUMAN
- Pathway: Protein modification; protein ubiquitination.
Interacting Proteins for AREL1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006915 | apoptotic process | IEA | -- |
| GO:0016567 | protein ubiquitination | IEA | -- |
| GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process | IDA | 23479728 |
| GO:0043066 | negative regulation of apoptotic process | IDA | 23479728 |
No data available for SIGNOR curated interactions for AREL1 Gene
Transcripts for AREL1 Gene
mRNA/cDNA for AREL1 Gene
- (7) REFSEQ mRNAs :
- (254) Selected AceView cDNA sequences:
- (17) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for AREL1
-
Santa Cruz Biotechnology (SCBT) CRISPR for AREL1
- GenScript: Design CRISPR guide RNA sequences for AREL1
miRNA Products
- Search ViGene Biosciences for AREL1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for AREL1
- Browse OriGene Inhibitory RNA Products For AREL1
-
ViGene Biosciences ready-to-package AAV shRNAs for AREL1 gene
Clone Products
-
OriGene ORF clones in human for AREL1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for AREL1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AREL1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | · | 9c | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b | · | 13c | ^ | 14 | ^ | 15a | · | 15b | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
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| SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP13: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP14: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP15: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP16: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP17: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP18: | - | - |
| ExUns: | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20a | · | 20b | ^ | 21a | · | 21b | ^ | 22a | · | 22b | ^ | 23 | ^ | 24 | ^ | 25a | · | 25b | ^ | 26a | · | 26b | ^ | 27a | · | 27b | ^ | 28 | ^ | 29 | ^ | 30 | ^ | 31 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||||||||||||||||||||||
| SP8: | |||||||||||||||||||||||||||||||||||||||||||
| SP9: | |||||||||||||||||||||||||||||||||||||||||||
| SP10: | |||||||||||||||||||||||||||||||||||||||||||
| SP11: | |||||||||||||||||||||||||||||||||||||||||||
| SP12: | |||||||||||||||||||||||||||||||||||||||||||
| SP13: | |||||||||||||||||||||||||||||||||||||||||||
| SP14: | |||||||||||||||||||||||||||||||||||||||||||
| SP15: | |||||||||||||||||||||||||||||||||||||||||||
| SP16: | |||||||||||||||||||||||||||||||||||||||||||
| SP17: | |||||||||||||||||||||||||||||||||||||||||||
| SP18: |
Expression for AREL1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Proerythroblasts Hematopoietic Bone Marrow
This gene is overexpressed in CD8 Tcells (35.6) and Retina (33.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for AREL1 Gene
NURSA nuclear receptor signaling pathways regulating expression of AREL1 Gene:
AREL1Evidence on tissue expression from TISSUES for AREL1 Gene
- Nervous system(4.7)
Primer Products
-
OriGene qPCR primer pairs for AREL1
-
OriGene qPCR primer pairs and template standards for AREL1
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for AREL1 Gene
Orthologs for AREL1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | AREL1 34 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | AREL1 35 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | AREL1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | AREL1 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Arel1 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Arel1 34 16 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
OneToMany | |
| -- 35 |
|
OneToMany | |||
| chicken (Gallus gallus) |
Aves | AREL1 35 |
|
OneToOne | |
| KIAA0317 34 |
|
||||
| lizard (Anolis carolinensis) |
Reptilia | AREL1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | arel1 34 |
|
||
| Str.10388 34 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.12564 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LOC100332031 34 |
|
||
| AREL1 35 |
|
OneToOne | |||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP009516 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG4238 34 35 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.948 35 |
|
OneToOne |
- Species where no ortholog for AREL1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for AREL1 Gene
Paralogs for AREL1 Gene
(20) SIMAP similar genes for AREL1 Gene using alignment to 9 proteins:
Variants for AREL1 Gene
| SNP ID | Clin | Chr 14 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000065189 | -- | 74,677,724(+) | TCTCA(A/G)ACTCC | intron-variant | |
| rs1000124777 | -- | 74,712,467(+) | GAAAA(A/G)AGCTA | intron-variant, upstream-variant-2KB | |
| rs1000147040 | -- | 74,684,280(+) | GACCT(A/C)TTAAA | intron-variant | |
| rs1000153733 | -- | 74,686,758(+) | TTGAG(A/G)AATGA | intron-variant | |
| rs1000237749 | -- | 74,673,543(+) | GATAT(A/G)TTAAA | intron-variant |
Residual Variation Intolerance Score:
11.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.61;
45.20% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for AREL1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for AREL1 Gene
Disorders for AREL1 Gene
Relevant External Links for AREL1
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- AREL1
No disorders were found for AREL1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for AREL1 Gene
Publications for AREL1 Gene
- Identification of a novel anti-apoptotic E3 ubiquitin ligase that ubiquitinates antagonists of inhibitor of apoptosis proteins SMAC, HtrA2, and ARTS. (PMID: 23479728) Kim J.B. … Shin D.Y. (J. Biol. Chem. 2013) 2 3 4 64
- Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PMID: 9205841) Nagase T. … Ohara O. (DNA Res. 1997) 2 3 4 64
- Ubiquitin E3 ligase FIEL1 regulates fibrotic lung injury through SUMO-E3 ligase PIAS4. (PMID: 27162139) Lear T. … Chen B.B. (J. Exp. Med. 2016) 2 3 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R. … Weissenbach J. (Nature 2003) 3 4 64
Products for AREL1 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
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- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
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- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for AREL1
- Search Origene for MassSpec and Protein Over-expression Lysates for AREL1
- Origene Custom Protein Services for AREL1
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for AREL1
- Browse OriGene Inhibitory RNA Products For AREL1
- OriGene qPCR primer pairs for AREL1
- OriGene qPCR primer pairs and template standards for AREL1
- OriGene CRISPR knockouts for AREL1
- OriGene ORF clones in human for AREL1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For AREL1
- GenScript: Next-day shipping cDNA ORF clone for AREL1 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for AREL1
- GenScript Custom Assay Services for AREL1
- GenScript Custom overexpressing Cell Line Services for AREL1
- GenScript: Design CRISPR guide RNA sequences for AREL1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
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- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
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- Novus Biologicals Antibodies for AREL1
- Novus Biologicals proteins and lysates for AREL1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ViGene Biosciences adenoviral particle packaged cDNA for AREL1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for AREL1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for AREL1 gene
- Search ViGene Biosciences for AREL1
- Horizon Cell Lines for AREL1
- Cyagen custom Knockout/knockin (KOKI) mouse models for AREL1
- VectorBuilder custom plasmid, inducible vectors for AREL1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AREL1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for AREL1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
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- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
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- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer