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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ARCN1 Gene

protein-coding GIFtS: 62
GCID: GC11P118444

archain 1

(Previous names: coatomer protein complex, subunit delta )
(Previous symbol: COPD)

Explore 5 diseases affiliated with
ARCN1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Archain 1¹ ²		Coatomer Protein Delta-COP²
COPD¹ ² ³		Coatomer Subunit Delta²
Coatomer Protein Complex, Subunit Delta¹ ²		Delta-COP³
Delta-Coat Protein² ³		Archain³
Archain Vesicle Transport Protein 1²		Delta-COP³
Coatomer Delta Subunit²

External Ids:	HGNC: 649¹	Entrez Gene: 372²	Ensembl: ENSG00000095139⁷	OMIM: 600820⁵	UniProtKB: P48444³

Export aliases for ARCN1 gene to outside databases

Previous GC identifers: GC11P120799 GC11P119954 GC11P118477 GC11P117980 GC11P117948 GC11P114380

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ARCN1:

This gene maps in a region, which include the mixed lineage leukemia and Friend leukemia virus integration 1 genes,

where multiple disease-associated chromosome translocations occur. It is an intracellular protein. Archain sequences

are well conserved among eukaryotes and this protein may play a fundamental role in eukaryotic cell biology. It has

similarities to heat shock proteins and clathrin-associated proteins, and may be involved in vesicle structure or

trafficking. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: COPD_HUMAN, P48444

Function: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with

Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up

to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the

retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by

membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also

influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL

receptors (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000011.9 NC_018922.1 NT_033899.8

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ARCN1 gene promoter:
Elk-1 AML1a AP-4 Evi-1 AREB6 NRF-2 POU2F1 POU2F1a Msx-1 TGIF
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ARCN1 promoter sequence

Search SABiosciences Chromatin IP Primers for ARCN1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARCN1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q23.3 Ensembl cytogenetic band: 11q23.3 HGNC cytogenetic band: 11q23.3

ARCN1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARCN1 gene location

GeneLoc information about chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11P118444: view genomic region (about GC identifiers)

Start:	118,443,102 bp from pter	End:	118,473,748 bp from pter
Size:	30,647 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: COPD_HUMAN, P48444 (See protein sequence)

Recommended Name: Coatomer subunit delta

Size: 511 amino acids; 57210 Da

Subunit: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits

Subcellular location: Cytoplasm (By similarity). Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic

side (By similarity). Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side

(By similarity). Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on

the vesicles/buds originating from it (By similarity)

Sequence caution: Sequence=CAA57072.1; Type=Erroneous initiation;

Secondary accessions: B4E1X2 E9PEU4 Q52M80

Alternative splicing: 2 isoforms: P48444-1 P48444-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ARCN1: NX_P48444

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P48444

ARCN1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001135753.1 NP_001646.2

ENSEMBL proteins:

ENSP00000376599 ENSP00000352385 ENSP00000431676 ENSP00000264028

Reactome Protein details: P48444
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	Uscn Proteins for ARCN1

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005829	cytosol	TAS	--
GO:0030126	COPI vesicle coat	ISS	--
GO:0030131	clathrin adaptor complex	IEA	--

ARCN1 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ARCN1 for domains About GeneDecksing

4 InterPro domains/families:

IPR008968 Clathrin_mu_C

IPR022775 AP_mu_sigma_su

IPR011012 Longin-like_dom

IPR027059 Coatomer_dsu

Graphical View of Domain Structure for InterPro Entry P48444

ProtoNet protein and cluster: P48444

1 Blocks protein family: IPB001392 Clathrin adaptor complex

UniProtKB/Swiss-Prot: COPD_HUMAN, P48444

Similarity: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily

Similarity: Contains 1 MHD (mu homology) domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: COPD_HUMAN, P48444

Function: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with

Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up

to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the

retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by

membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also

influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL

receptors (By similarity)

Genatlas biochemistry entry for ARCN1:

archain,homologous to DNA sequences from Drosophila and mice

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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARCN1

12 GenomeRNAi human phenotypes for ARCN1:

Decreased Hepatitis C virus re	Decreased Salmonella enterica	Decreased Salmonella-containin	Decreased Wnt reporter activit
Decreased cell number, increas	Decreased homologous recombina	Decreased influenza A virus in	Decreased influenza A/WSN/33 r
Decreased viability	G0/1 arrest	Increased Salmonella enterica	Increased gamma-H2AX phosphory

Animal Models:
8 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Arcn1):

behavior/neurological	cellular	growth/size	hematopoietic system	integument
limbs/digits/tail	nervous system	pigmentation

ARCN1 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Coatomer:Arf1-GTP:GAP lattice formation on golgi membrane

Coatomer:Arf1-GTP:GAP lattice formation on golgi membrane	1.00	COPI Mediated Transport	0.90
Hydrolysis of Arf1-GTP to Arf1-GDP	1.00	Golgi vesicle lattice disassociation	0.89
Diffusion of inactive Arf1-GDP from membrane	1.00	Cholesterol and Sphingolipids transport / Transport from Golgi and ER to the apical membrane (normal and CF)	0.32
Golgi to ER Retrograde Transport	0.90

Clathrin-dependent protein traffic

	Clathrin-dependent protein traffic	1.00			wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF)	0.37
	Transport_Clathrin-coated vesicle cycle	0.66

COPII (Coat Protein 2) Mediated Vesicle Transport

Normal wtCFTR traffic / ER-to-Golgi

0.36

Delta508-CFTR traffic / ER-to-Golgi in CF

0.36

Membrane Trafficking

Membrane Trafficking

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

1 EMD Millipore Pathway for ARCN1

Clathrin-dependent protein traffic

5 GeneGo (Thomson Reuters) Pathways for ARCN1

	wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF)
	Delta508-CFTR traffic / ER-to-Golgi in CF
	Cholesterol and Sphingolipids transport / Transport from Golgi and ER to the apical membrane (normal and CF)
	Normal wtCFTR traffic / ER-to-Golgi
	Transport Clathrin-coated vesicle cycle

5/7 Reactome Pathways for ARCN1 (see all 7)

	Hydrolysis of Arf1-GTP to Arf1-GDP
	Diffusion of inactive Arf1-GDP from membrane
	Membrane Trafficking
	COPI Mediated Transport
	Golgi to ER Retrograde Transport

ARCN1 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for ARCN1

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/888 Interacting proteins for ARCN1 (P48444^{2, 3} ENSP00000264028⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 888)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
COPA	P53621²^,³, ENSP00000357048⁴	MINT-7945693 MINT-8217717 MINT-7947479 I2D: score=7 STRING: ENSP00000357048
COPB1	P53618²^,³, ENSP00000249923⁴	MINT-7945693 MINT-8217717 MINT-7947479 I2D: score=12 STRING: ENSP00000249923
COPG1	Q9Y678²^,³, ENSP00000325002⁴	MINT-7945693 MINT-8217717 MINT-7947479 I2D: score=1 STRING: ENSP00000325002
COPB2	P35606²^,³, ENSP00000329419⁴	MINT-7945693 MINT-7947479 I2D: score=2 STRING: ENSP00000329419
ACTB	P60709²^,³	MINT-7945693 MINT-7947479 I2D: score=1

About this table

Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006886	intracellular protein transport	IEA	--
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	TAS	--
GO:0016044	cellular membrane organization	TAS	--
GO:0016192	vesicle-mediated transport	--	--
GO:0048205	COPI coating of Golgi vesicle	TAS	--

ARCN1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ARCN1

1 HMDB Compound for ARCN1 About this table

Compound	Synonyms	CAS #	PubMed Ids
Guanosine triphosphate	5'-GTP (see all 10)	86-01-1	--

Search CenterWatch for drugs/clinical trials and news about ARCN1 / COPD

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ARCN1 gene (2 alternative transcripts):

NM_001142281.1 NM_001655.4

Unigene Cluster for ARCN1:

Archain 1

Hs.33642 [show with all ESTs]

Unigene Representative Sequence: BX640860

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000392859 ENST00000359415(uc001ptq.3 uc010ryg.2 uc009zag.3)

ENST00000533452 ENST00000534182 ENST00000264028

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		hsa-miR-548j hsa-miR-3938 hsa-miR-361-5p hsa-miR-517a hsa-miR-374a hsa-miR-578 hsa-miR-877* hsa-miR-1243

		SwitchGear 3'UTR luciferase reporter plasmid: ARCN1 3' UTR sequence

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Additional cDNA sequence:

AK304019.1 AK312298.1 BC064936.1 BC080638.1 BC093636.1 BC093638.1 BX640860.1 X81197.1

18 DOTS entries:

DT.100797134 DT.100735790 DT.95118968 DT.101981263 DT.100797132 DT.100865355 DT.455908 DT.91811393

DT.120717195 DT.100797137 DT.86844962 DT.91759191 DT.100836269 DT.120717246 DT.100027800 DT.100797135

DT.120717272 DT.120717209

24/755 AceView cDNA sequences (see all 755):

BU556780 AK074918 BF313771 BM997045 AI886101 CB123755 AW474078 AK125783

BM972233 AA826917 CR619909 BE276640 AI022977 AI961853 BU682165 AU129758

BG389923 BU184041 F02357 W38321 AW003672 CA412272 BM703475 BU172151

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ARCN1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTAGTTAAGC

About this image

ARCN1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

HSF-1 (UC01) (Embryonic Stem Cell)

Early Embryo, Inner Cell Mass

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See ARCN1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ARCN1

SOURCE GeneReport for Unigene cluster: Hs.33642

UniProtKB/Swiss-Prot: COPD_HUMAN, P48444

Tissue specificity: Ubiquitously expressed

SABiosciences Custom PCR Arrays for ARCN1

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In Situ
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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for ARCN1 gene from 9/37 species (see all 37) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Arcn1^{1 , 5}	archain 1^{1, 5}	92.5(n)¹ 99.02(a)¹		9 (24.84 cM)⁵ 213827¹ NM_145985.4¹ NP_666097.3¹ 44741564⁵
chicken (Gallus gallus)	Aves	ARCN1¹	archain 1	81.44(n) 94.9(a)		770561 NM_001079499.1 NP_001072967.1
lizard (Anolis carolinensis)	Reptilia	ARCN1⁶	--	92(a)	1 ↔ 1	GL343767.1(16056-23001)
African clawed frog (Xenopus laevis)	Amphibia	arcn1-prov²	archain 1	77.93(n)		BC056030.1
zebrafish (Danio rerio)	Actinopterygii	BC050499.1²	--	75.84(n)		BC050499.1
fruit fly (Drosophila melanogaster)	Insecta	&dgr;COP³ deltaCOP¹	retrograde (Golgi to ER) transport³ delta-coatomer protein¹	56(a)³ 58.22(n)¹ 61.1(a)¹		45250¹ NM_001169171.1¹ NP_001162642.1¹
worm (Caenorhabditis elegans)	Secernentea	C13B9.3^{1 , 3}	Protein C13B9.3¹	47(a)³ 54.48(n)¹ 52.81(a)¹		III(6694709-6696721)³ 175940¹ NM_066062.3¹ NP_498463.1¹
thale cress (Arabidopsis thaliana)	eudicotyledons	AT5G05010¹	coatomer subunit delta	53.17(n) 41.47(a)		830383 NM_001036759.2 NP_001031836.1
rice (Oryza sativa)	Liliopsida	NM_190465.1²	--	73.94(n)		NM_190465.1

ENSEMBL Gene Tree for ARCN1 (if available)
TreeFam Gene Tree for ARCN1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 11 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs147682852^1,2		--	118441228(+)	`GCACTC/GAATTA`	2	--	us2k¹		0	--	--	--	--
rs116159478^1,2	F,	--	118441262(+)	`TGGACA/CTACAG`	2	--	us2k¹		1		WA	118
rs142436559^1,2		--	118441470(+)	`TTTTCA/GCCATT`	2	--	us2k¹		0	--	--	--	--
rs186600712^1,2		--	118441538(+)	`TTAAAC/GATATA`	2	--	us2k¹		0	--	--	--	--
rs192020608^1,2		--	118441554(+)	`CAAATA/CATAAA`	2	--	us2k¹		0	--	--	--	--
rs504193^1,2	C,H	--	118441582(-)	`TAAATT/GGTATA`	2	--	us2k¹		5		EA NS NA	270
rs183783557^1,2		--	118441620(+)	`TAGTTC/TCAGAA`	2	--	us2k¹		0	--	--	--	--
rs187664191^1,2		--	118441695(+)	`AAGCCA/GTCCTC`	2	--	us2k¹		0	--	--	--	--
rs75800397^1,2		--	118441783(+)	`TTCCAG/TAAATA`	2	--	us2k¹		2		CSA WA	120
rs10892243^1,2	C,F,A,H,	--	118441846(+)	`GGAAAT/CCACTA`	2	--	us2k¹ tfbs³		20		NS EA NA CSA WA	2377

HapMap Linkage Disequilibrium report for ARCN1 (118443102 - 118473748 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ARCN1: --

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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ARCN1 for disorders           About GeneDecksing

OMIM gene information: 600820    OMIM disorders: --

5 diseases for ARCN1:    About MalaCards

leukemia copd cholesterol thyroiditis

malaria

Export disorders for ARCN1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for ARCN1 gene, integrated from 9 sources (see all 40):
(articles sorted by number of sources associating them with ARCN1)

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The human archain gene, ARCN1, has highly conserved homologs in rice and Drosophila. (PubMed id 7782067)^{1, 2, 3, 9} Radice P....Tunnacliffe A. (1995)
The coatomer protein delta-COP, encoded by the archain gene, is conserved across diverse eukaryotes. (PubMed id 8854871)^{1, 3, 9} Tunnacliffe A....Radice P. (1996)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (2012)
Crystallization and preliminary X-ray analysis of the C-terminal domain of d-COP, a medium-sized subunit of the COPI complex involved in membrane trafficking. (PubMed id 22750876)¹ Deng K....Sun Z. (2012)
Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)¹ Udeshi N.D....Carr S.A. (2012)
A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)¹ Kristensen A.R....Foster L.J. (2012)
Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)¹ Oshikawa K....Nakayama K.I. (2012)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 372	HGNC: 649	AceView: ARCN1andPHLDB1	Ensembl:ENSG00000095139	euGenes: HUgn372
ECgene: ARCN1	H-InvDB: ARCN1

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for ARCN1	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for ARCN1	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for ARCN1 gene
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Patent Information for ARCN1 gene:
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