Aliases for ARAP3 Gene
Aliases for ARAP3 Gene
External Ids for ARAP3 Gene
- HGNC: 24097
- Entrez Gene: 64411
- Ensembl: ENSG00000120318
- OMIM: 606647
- UniProtKB: Q8WWN8
Previous HGNC Symbols for ARAP3 Gene
- CENTD3
Previous GeneCards Identifiers for ARAP3 Gene
- GC05M140849
- GC05M141615
- GC05M141016
- GC05M141061
- GC05M141013
- GC05M136177
- GC05M141032
Summaries for ARAP3 Gene
-
This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangements in the cell cytoskeleton and cell shape. It is a specific PtdIns(3,4,5)P3/PtdIns(3,4)P2-stimulated Arf6-GAP protein. An alternatively spliced transcript has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Sep 2015]
GeneCards Summary for ARAP3 Gene
ARAP3 (ArfGAP With RhoGAP Domain, Ankyrin Repeat And PH Domain 3) is a Protein Coding gene. Among its related pathways are Class I PI3K signaling events and Ras signaling pathway. GO annotations related to this gene include GTPase activator activity and phosphatidylinositol-3,4-bisphosphate binding. An important paralog of this gene is ARAP2.
UniProtKB/Swiss-Prot for ARAP3 Gene
-
Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARAP3 Gene
Genomics for ARAP3 Gene
Regulatory Elements for ARAP3 Gene
Enhancers for ARAP3 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around ARAP3 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the ARAP3 gene promoter:
Regulatory Element Products
Genomic Location for ARAP3 Gene
- Chromosome:
- 5
- Start:
- 141,653,401 bp from pter
- End:
- 141,682,233 bp from pter
- Size:
- 28,833 bases
- Orientation:
- Minus strand
Genomic View for ARAP3 Gene
Genes around ARAP3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 5q31.3 by Ensembl
- 5q31.3 by Entrez Gene
- 5q31.3 by HGNC
ARAP3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ARAP3 Gene
Proteins for ARAP3 Gene
-
Protein details for ARAP3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8WWN8-ARAP3_HUMAN
- Recommended name:
- Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
- Protein Accession:
- Q8WWN8
- B4DIT1
- D3DQE3
Protein attributes for ARAP3 Gene
- Size:
- 1544 amino acids
- Molecular mass:
- 169844 Da
- Quaternary structure:
-
- Interacts (via SAM domain) with INPPL1/SHIP2.
Three dimensional structures from OCA and Proteopedia for ARAP3 Gene
Protein Expression for ARAP3 Gene
Post-translational modifications for ARAP3 Gene
- Tyrosine phosphorylated at a low basal level. PDGF treatment stimulates phosphorylation. Tyrosine phosphorylation is increased in cells that are in the process of becoming attached to a substrate and that start spreading and flattening (By similarity).
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for ARAP3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for ARAP3
-
Custom Antibody ServicesOriGene Antibodies for ARAP3
- Novus Biologicals Antibodies for ARAP3
- Invitrogen Antibodies for ARAP3
- antibodies-online Antibodies for ARAP3: See all 23
- GeneTex ARAP3 antibody for ARAP3
Protein Products
-
OriGene Purified Proteins for ARAP3
- Search Origene for MassSpec and Protein Over-expression Lysates for ARAP3
- Origene Custom Protein Services for ARAP3
- Search GeneTex for Proteins for ARAP3
Assay Products
- antibodies-online Kits for ARAP3: See all 5
No data available for DME Specific Peptides for ARAP3 Gene
Domains & Families for ARAP3 Gene
Gene Families for ARAP3 Gene
Protein Domains for ARAP3 Gene
Suggested Antigen Peptide Sequences for ARAP3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for ARAP3 Gene
Function for ARAP3 Gene
Molecular function for ARAP3 Gene
- UniProtKB/Swiss-Prot Function:
- Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005096 | GTPase activator activity | IEA,TAS | -- |
| GO:0005515 | protein binding | IPI | 15090612 |
| GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding | IDA | 11804589 |
| GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding | IDA | 11804589 |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for ARAP3 Gene
- MGI mutant phenotypes for ARAP3:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for ARAP3:
-
- Decreased ionizing radiation sensitivity
- Increased shRNA abundance (Z-score > 2)
- Dynamic nuclei (hole, folded or small irregular)
- Decreased shRNA abundance (Z-score < -2)
- Decreased focal adhesion (FA) area, decreased FA length, decreased FA mean intensity, increased number of small and round FAs, increased FA abundance
- Decreased shRNA abundance
Animal Models for ARAP3 Gene
- MGI Knock Outs for ARAP3:
-
- Arap3 tm1.2Sve
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ARAP3
-
-
ViGene Biosciences lentiviral particle packaged cDNA for ARAP3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ARAP3 gene
- Search ViGene Biosciences for ARAP3
CRISPR Products
-
OriGene CRISPR knockouts for ARAP3
-
Santa Cruz Biotechnology (SCBT) CRISPR for ARAP3
- GenScript: Design CRISPR guide RNA sequences for ARAP3
miRNA Products
- Search ViGene Biosciences for ARAP3
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for ARAP3
- Browse OriGene Inhibitory RNA Products For ARAP3
-
ViGene Biosciences ready-to-package AAV shRNAs for ARAP3 gene
Clone Products
-
OriGene ORF clones in human for ARAP3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for ARAP3
- VectorBuilder custom plasmid, inducible vectors for ARAP3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ARAP3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for ARAP3
-
ViGene Biosciences adenoviral particle packaged cDNA for ARAP3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ARAP3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ARAP3 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for ARAP3 Gene
Localization for ARAP3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ARAP3 Gene
- Cytoplasm. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein. Cell projection, lamellipodium. Cell projection, ruffle. Note=Cytoplasmic, and associated with F-actin-rich membrane ruffles and lamellipodia. {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| cytoskeleton | 4 |
| plasma membrane | 3 |
| nucleus | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001726 | ruffle | ISS | -- |
| GO:0005737 | cytoplasm | ISS | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0005856 | cytoskeleton | IEA | -- |
| GO:0005886 | plasma membrane | IEA | -- |
Pathways & Interactions for ARAP3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | cAMP signaling pathway | ||
| 2 | Endocytosis | ||
| 3 | Ras signaling pathway | ||
| 4 | p75 NTR receptor-mediated signalling |
.36
|
|
| 5 | Signaling by GPCR | ||
Pathways by source for ARAP3 Gene
2 BioSystems pathways for ARAP3 Gene
3 Reactome pathways for ARAP3 Gene
3 KEGG pathways for ARAP3 Gene
Interacting Proteins for ARAP3 Gene
Selected Interacting proteins:
ENSP00000239440
Q8WWN8-ARAP3_HUMAN
for ARAP3 Gene via
STRING
MINT
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007010 | cytoskeleton organization | TAS | 15569923 |
| GO:0007165 | signal transduction | IEA | -- |
| GO:0008360 | regulation of cell shape | ISS | -- |
| GO:0016192 | vesicle-mediated transport | TAS | 15569923 |
| GO:0030336 | negative regulation of cell migration | ISS | -- |
No data available for SIGNOR curated interactions for ARAP3 Gene
Transcripts for ARAP3 Gene
mRNA/cDNA for ARAP3 Gene
- (7) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (120) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ARAP3 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ARAP3
-
Santa Cruz Biotechnology (SCBT) CRISPR for ARAP3
- GenScript: Design CRISPR guide RNA sequences for ARAP3
miRNA Products
- Search ViGene Biosciences for ARAP3
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for ARAP3
- Browse OriGene Inhibitory RNA Products For ARAP3
-
ViGene Biosciences ready-to-package AAV shRNAs for ARAP3 gene
Clone Products
-
OriGene ORF clones in human for ARAP3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for ARAP3
- VectorBuilder custom plasmid, inducible vectors for ARAP3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ARAP3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ | 14a | · | 14b | · | 14c | ^ | 15 | ^ | 16a | · | 16b | ^ | 17 | ^ | 18 | ^ | 19a | · | 19b | · | 19c | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
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| SP12: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP13: |
| ExUns: | 20 | ^ | 21a | · | 21b | ^ | 22a | · | 22b | ^ | 23a | · | 23b | ^ | 24a | · | 24b | ^ | 25 | ^ | 26a | · | 26b | ^ | 27a | · | 27b | ^ | 28 | ^ | 29a | · | 29b | ^ | 30 | ^ | 31 | ^ | 32 | ^ | 33 | ^ | 34 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | ||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | ||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP10: | |||||||||||||||||||||||||||||||||||||||||||
| SP11: | |||||||||||||||||||||||||||||||||||||||||||
| SP12: | |||||||||||||||||||||||||||||||||||||||||||
| SP13: |
Expression for ARAP3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Skeletal Muscle (Muscoskeletal System)
- Mononuclear Myocytes Hyoid Arch Muscles
- Mononuclear Myocytes Mandibular Arch Muscles
- Paraxial Mesoderm Cells Branchial Arch 1
- Myoblasts Mandibular Arch Muscles
- Muscle Progenitor Cells Mandibular Arch Muscles
- Inner Cell Mass (Early Embryonic Tissues)
-
Head Mesenchyme (Muscoskeletal System)
- Paraxial Mesoderm Cells Branchial Arch 1
-
Bone (Muscoskeletal System)
- Paraxial Mesoderm Cells Branchial Arch 1
-
Dermis (Integumentary System)
- Dermal Fibroblasts Dorsal Dermis
-
Fibroblasts
- Dermal Fibroblasts Dorsal Dermis
mRNA differential expression in normal tissues according to GTEx for ARAP3 Gene
This gene is overexpressed in Whole Blood (x5.4).
This gene is overexpressed in Lavage (35.5) and Serum (30.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ARAP3 Gene
NURSA nuclear receptor signaling pathways regulating expression of ARAP3 Gene:
ARAP3SOURCE GeneReport for Unigene cluster for ARAP3 Gene:
Hs.726187Evidence on tissue expression from TISSUES for ARAP3 Gene
- Nervous system(4.4)
Primer Products
-
OriGene qPCR primer pairs for ARAP3
No data available for Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ARAP3 Gene
Orthologs for ARAP3 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ARAP3 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | ARAP3 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | ARAP3 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Arap3 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Arap3 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | ARAP3 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | ARAP3 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ARAP3 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | ARAP3 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | arap3 34 |
|
||
| Str.16223 34 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | arap3 34 35 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | RhoGAP15B 36 35 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | F23H11.4 35 |
|
OneToMany | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | AGE1 35 |
|
OneToMany |
- Species where no ortholog for ARAP3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for ARAP3 Gene
(6) SIMAP similar genes for ARAP3 Gene using alignment to 6 proteins:
Variants for ARAP3 Gene
| SNP ID | Clin | Chr 05 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs61749636 | A breast cancer sample | 141,654,303(+) | CCGTG(G/T)GGTGG | reference, missense | |
| VAR_036180 | A colorectal cancer sample | ||||
| VAR_036181 | A breast cancer sample | ||||
| rs145752053 | Uncertain significance | 141,662,250(+) | CAGCC(A/G)GAGCC | intron-variant, nc-transcript-variant, reference, missense | |
| rs1000020516 | -- | 141,678,544(+) | CCCTC(-/TTT)TTTTT | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2730848 | CNV | deletion | 23290073 |
| esv3606989 | CNV | loss | 21293372 |
| nsv1109732 | CNV | deletion | 24896259 |
| nsv1154058 | CNV | deletion | 26484159 |
| nsv472203 | CNV | novel sequence insertion | 20440878 |
| nsv5034 | CNV | insertion | 18451855 |
Residual Variation Intolerance Score:
33.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.70;
78.64% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ARAP3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ARAP3
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ARAP3 Gene
Disorders for ARAP3 Gene
Relevant External Links for ARAP3
No disorders were found for ARAP3 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ARAP3 Gene
Publications for ARAP3 Gene
- Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices. (PMID: 11804589) Krugmann S. … Hawkins P.T. (Mol. Cell 2002) 2 3 4 22 64
- EST-based genome-wide gene inactivation identifies ARAP3 as a host protein affecting cellular susceptibility to anthrax toxin. (PMID: 15569923) Lu Q. … Cohen S.N. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 22 64
- GTPase signaling: bridging the GAP between ARF and Rho. (PMID: 12015138) Santy L.C. … Casanova J.E. (Curr. Biol. 2002) 2 3 4 64
- The PI3K effector Arap3 interacts with the PI(3,4,5)P3 phosphatase SHIP2 in a SAM domain-dependent manner. (PMID: 17314030) Raaijmakers J.H. … Bos J.L. (Cell. Signal. 2007) 3 4 64
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
Products for ARAP3 Gene
- Browse R&D Systems for Antibodies
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- Browse R&D Systems for biochemical assays
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- Custom Antibody ServicesOriGene Antibodies for ARAP3
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- OriGene Purified Proteins for ARAP3
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- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for ARAP3
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- OriGene qPCR primer pairs for ARAP3
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Next-day shipping cDNA ORF clone for ARAP3 in any vector
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- GenScript: Design CRISPR guide RNA sequences for ARAP3
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for ARAP3
- Novus Biologicals proteins and lysates for ARAP3
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Addgene plasmids for ARAP3
- antibodies-online Antibodies for ARAP3: See all 23
- antibodies-online Kits for ARAP3: See all 5
- Search antibodies-online for proteins
- Search antibodies-online for peptides
- GeneTex ARAP3 antibody for ARAP3
- Search GeneTex for Proteins for ARAP3
- ViGene Biosciences adenoviral particle packaged cDNA for ARAP3 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ARAP3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ARAP3 gene
- Search ViGene Biosciences for ARAP3
- Horizon Cell Lines for ARAP3
- Cyagen custom Knockout/knockin (KOKI) mouse models for ARAP3
- VectorBuilder custom plasmid, inducible vectors for ARAP3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ARAP3
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ARAP3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer