Aliases for AQR Gene
External Ids for AQR Gene
Previous GeneCards Identifiers for AQR Gene
GeneCards Summary for AQR Gene
AQR (Aquarius Intron-Binding Spliceosomal Factor) is a Protein Coding gene. Among its related pathways are DNA Double-Strand Break Repair and mRNA Splicing - Major Pathway. GO annotations related to this gene include poly(A) RNA binding. An important paralog of this gene is SETX.
UniProtKB/Swiss-Prot for AQR Gene
Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.