Aliases for AQR Gene
Aliases for AQR Gene
External Ids for AQR Gene
- HGNC: 29513
- Entrez Gene: 9716
- Ensembl: ENSG00000021776
- OMIM: 610548
- UniProtKB: O60306
Previous GeneCards Identifiers for AQR Gene
- GC15M030490
- GC15M028043
- GC15M032726
- GC15M032863
- GC15M032935
- GC15M035147
- GC15M011994
Summaries for AQR Gene
GeneCards Summary for AQR Gene
AQR (Aquarius Intron-Binding Spliceosomal Factor) is a Protein Coding gene. Among its related pathways are mRNA Splicing - Major Pathway and Transcription-Coupled Nucleotide Excision Repair (TC-NER). GO annotations related to this gene include poly(A) RNA binding. An important paralog of this gene is ZNFX1.
UniProtKB/Swiss-Prot for AQR Gene
-
Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AQR Gene
Genomics for AQR Gene
Regulatory Elements for AQR Gene
Enhancers for AQR Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around AQR on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the AQR gene promoter:
Regulatory Element Products
Genomic Location for AQR Gene
- Chromosome:
- 15
- Start:
- 34,851,782 bp from pter
- End:
- 34,969,839 bp from pter
- Size:
- 118,058 bases
- Orientation:
- Minus strand
Genomic View for AQR Gene
Genes around AQR on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 15q14 by Ensembl
- 15q14 by Entrez Gene
- 15q14 by HGNC
AQR Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for AQR Gene
Proteins for AQR Gene
-
Protein details for AQR Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O60306-AQR_HUMAN
- Recommended name:
- Intron-binding protein aquarius
- Protein Accession:
- O60306
- A0JP17
- A5YKK3
- Q2YDX9
- Q6IRU8
- Q6PIC8
Protein attributes for AQR Gene
- Size:
- 1485 amino acids
- Molecular mass:
- 171295 Da
- Quaternary structure:
-
- Identified in the spliceosome C complex. Component of the XAB2 complex, a multimeric protein complex composed of XAB2, PRPF19, AQR, ZNF830, ISY1, and PPIE.
- SequenceCaution:
-
- Sequence=BAA25486.3; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
Protein Expression for AQR Gene
Post-translational modifications for AQR Gene
Other Protein References for AQR Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for AQR
- Novus Biologicals Antibodies for AQR
- Invitrogen Antibodies for AQR
- antibodies-online Antibodies for AQR: See all 23
- GeneTex AQR antibody for AQR
Protein Products
-
OriGene Purified Proteins for AQR
- Search Origene for MassSpec and Protein Over-expression Lysates for AQR
- Origene Custom Protein Services for AQR
- Novus Biologicals proteins for AQR
- Search GeneTex for Proteins for AQR
Assay Products
No data available for DME Specific Peptides for AQR Gene
Domains & Families for AQR Gene
Gene Families for AQR Gene
Protein Domains for AQR Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for AQR Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O60306- Family:
-
- Belongs to the CWF11 family.
Function for AQR Gene
Molecular function for AQR Gene
- UniProtKB/Swiss-Prot Function:
- Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003723 | RNA binding | IDA,IEA | 22658674 |
| GO:0005515 | protein binding | IPI | 22365833 |
Phenotypes for AQR Gene
- MGI mutant phenotypes for AQR:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for AQR:
-
- Increased gamma-H2AX phosphorylation
- Decreased hepcidin::fluc mRNA expression
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased NF-kappaB reporter expression
- FOXO1 nuclear localization
- Increased shRNA abundance (Z-score > 2)
- Increased G1 DNA content
- Decreased IL-8 secretion
- Decreased viability
- Decreased shRNA abundance (Z-score < -2)
- Decreased shRNA abundance
- Weakly decreased NFAT1-GFP nuclear translocation
- Decreased cell number
- Decreased influenza A virus infection
- Negative genetic interaction between BLM-/- and BLM+/+
- Decreased HIV-1 infection
- HIV Rev nuclear localization
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for AQR
-
-
ViGene Biosciences lentiviral particle packaged cDNA for AQR gene
-
ViGene Biosciences ready-to-package AAV shRNAs for AQR gene
- Search ViGene Biosciences for AQR
CRISPR Products
-
OriGene CRISPR knockouts for AQR
-
Santa Cruz Biotechnology (SCBT) CRISPR for AQR
- GenScript: Design CRISPR guide RNA sequences for AQR
miRNA for AQR Gene
- miRTarBase miRNAs that target AQR
-
- hsa-mir-4326 (MIRT052840)
- hsa-mir-6513-5p (MIRT450612)
- hsa-mir-887-5p (MIRT450613)
- hsa-mir-3122 (MIRT450614)
- hsa-mir-3913-5p (MIRT450615)
- hsa-mir-450a-1-3p (MIRT450616)
- hsa-mir-6780a-5p (MIRT450617)
- hsa-mir-6779-5p (MIRT450618)
- hsa-mir-3689c (MIRT450619)
- hsa-mir-3689b-3p (MIRT450620)
- hsa-mir-3689a-3p (MIRT450621)
- hsa-mir-30b-3p (MIRT450622)
- hsa-mir-1273h-5p (MIRT450623)
- hsa-mir-6788-5p (MIRT450624)
- hsa-mir-30c-2-3p (MIRT450625)
- hsa-mir-30c-1-3p (MIRT450626)
- hsa-mir-3682-3p (MIRT450627)
- hsa-mir-4294 (MIRT450628)
- hsa-mir-924 (MIRT450629)
- hsa-mir-6807-5p (MIRT519552)
- hsa-mir-7151-3p (MIRT519553)
- hsa-mir-5095 (MIRT519554)
- hsa-mir-4252 (MIRT519555)
- hsa-mir-3130-3p (MIRT519556)
- hsa-mir-1273g-3p (MIRT519557)
- hsa-mir-941 (MIRT519558)
- hsa-mir-4438 (MIRT519560)
- hsa-mir-4465 (MIRT624695)
- hsa-mir-26b-5p (MIRT624696)
- hsa-mir-26a-5p (MIRT624697)
- hsa-mir-1297 (MIRT624698)
- hsa-mir-4772-3p (MIRT624699)
- hsa-mir-6787-3p (MIRT624700)
- hsa-mir-1304-3p (MIRT624701)
- hsa-mir-4532 (MIRT624702)
- hsa-mir-1247-3p (MIRT624703)
- hsa-mir-6736-3p (MIRT624704)
- hsa-mir-6890-3p (MIRT624705)
- hsa-mir-3180-5p (MIRT636717)
- hsa-mir-4314 (MIRT636718)
- hsa-mir-5195-3p (MIRT636719)
- hsa-mir-145-5p (MIRT636720)
- hsa-mir-4277 (MIRT636721)
- hsa-mir-6874-3p (MIRT636722)
- hsa-mir-148b-5p (MIRT636723)
- hsa-mir-3649 (MIRT642150)
- hsa-mir-659-5p (MIRT642151)
- hsa-mir-767-5p (MIRT642152)
- hsa-mir-1915-3p (MIRT642153)
- hsa-mir-6764-5p (MIRT642154)
- hsa-mir-6872-3p (MIRT642155)
- hsa-mir-7113-5p (MIRT642156)
- hsa-mir-211-3p (MIRT642157)
- hsa-mir-6892-5p (MIRT660563)
- hsa-mir-8085 (MIRT660564)
- hsa-mir-6731-5p (MIRT660565)
- hsa-mir-627-3p (MIRT660566)
- hsa-mir-6760-5p (MIRT660567)
- hsa-mir-4475 (MIRT660568)
- hsa-mir-551b-5p (MIRT660569)
- hsa-mir-548c-3p (MIRT660570)
- hsa-mir-8061 (MIRT660571)
- hsa-mir-665 (MIRT660572)
- hsa-mir-4760-5p (MIRT660573)
- hsa-mir-7106-3p (MIRT660574)
- hsa-mir-6756-3p (MIRT660575)
- hsa-mir-3127-3p (MIRT660576)
miRNA Products
- Search ViGene Biosciences for AQR
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for AQR
- Browse OriGene Inhibitory RNA Products For AQR
-
ViGene Biosciences ready-to-package AAV shRNAs for AQR gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for AQR
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AQR
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for AQR gene
-
ViGene Biosciences lentiviral particle packaged cDNA for AQR gene
-
ViGene Biosciences ready-to-package AAV shRNAs for AQR gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for AQR Gene
Localization for AQR Gene
Subcellular locations from UniProtKB/Swiss-Prot for AQR Gene
- Nucleus. Note=Localizes to speckle-like regions of the nucleoplasm. {ECO:0000269 PubMed:16949364}.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 2 |
| extracellular | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005681 | spliceosomal complex | IEA | -- |
| GO:0016020 | membrane | IDA | 19946888 |
| GO:0071013 | catalytic step 2 spliceosome | IDA | 11991638 |
Pathways & Interactions for AQR Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Transcription-Coupled Nucleotide Excision Repair (TC-NER) | ||
| 2 | mRNA Splicing - Major Pathway |
.79
|
.50
|
| 3 | DNA Double-Strand Break Repair |
.53
|
|
| 4 | Gene Expression |
.48
|
|
Pathways by source for AQR Gene
10 Reactome pathways for AQR Gene
1 KEGG pathway for AQR Gene
Interacting Proteins for AQR Gene
Selected Interacting proteins:
ENSP00000156471
O60306-AQR_HUMAN
for AQR Gene via
STRING
IID
MINT
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000398 | mRNA splicing, via spliceosome | TAS | -- |
| GO:0006283 | transcription-coupled nucleotide-excision repair | TAS | -- |
| GO:0006397 | mRNA processing | IEA | -- |
| GO:0008380 | RNA splicing | IEA | -- |
No data available for SIGNOR curated interactions for AQR Gene
Transcripts for AQR Gene
mRNA/cDNA for AQR Gene
- (1) REFSEQ mRNAs :
- (11) Additional mRNA sequences :
- (156) Selected AceView cDNA sequences:
- (6) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for AQR Gene
CRISPR Products
-
OriGene CRISPR knockouts for AQR
-
Santa Cruz Biotechnology (SCBT) CRISPR for AQR
- GenScript: Design CRISPR guide RNA sequences for AQR
miRNA Products
- Search ViGene Biosciences for AQR
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for AQR
- Browse OriGene Inhibitory RNA Products For AQR
-
ViGene Biosciences ready-to-package AAV shRNAs for AQR gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for AQR
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AQR
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18a | · | 18b | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: |
| ExUns: | 23 | ^ | 24 | ^ | 25 | ^ | 26 | ^ | 27 | ^ | 28 | ^ | 29a | · | 29b | ^ | 30 | ^ | 31 | ^ | 32 | ^ | 33a | · | 33b | ^ | 34a | · | 34b | ^ | 35 | ^ | 36a | · | 36b | · | 36c | · | 36d |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||||||||||||||||||
| SP6: |
Expression for AQR Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
This gene is overexpressed in Peripheral blood mononuclear cells (14.3), CD8 Tcells (7.3), and Lymph node (6.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for AQR Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of AQR Gene:
AQRSOURCE GeneReport for Unigene cluster for AQR Gene:
Hs.510958Evidence on tissue expression from TISSUES for AQR Gene
- Nervous system(4.5)
- Liver(4.2)
- Skin(2.5)
- Blood(2.3)
- Spleen(2.1)
Primer Products
-
OriGene qPCR primer pairs for AQR
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for AQR Gene
Orthologs for AQR Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | AQR 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | AQR 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | AQR 34 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | AQR 35 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Aqr 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Aqr 34 16 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | AQR 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | AQR 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | AQR 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | aqr 34 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.24067 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | aqr 34 35 |
|
||
| zgc63611 34 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.10294 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG31368 34 35 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP004028 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | emb-4 34 35 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | SEN1 35 |
|
OneToMany | |
| thale cress (Arabidopsis thaliana) |
eudicotyledons | EMB2765 34 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os03g0387000 34 |
|
||
| Os.20288 34 |
|
||||
| barley (Hordeum vulgare) |
Liliopsida | Hv.5034 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.5743 35 |
|
OneToOne | |
| bread mold (Neurospora crassa) |
Ascomycetes | NCU07866 34 |
|
||
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.3384 34 |
|
- Species where no ortholog for AQR was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for AQR Gene
Variants for AQR Gene
| SNP ID | Clin | Chr 15 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000038535 | -- | 34,901,284(+) | TAATG(C/T)TAAAG | intron-variant | |
| rs1000039319 | -- | 34,904,799(+) | GTACT(A/T)AGAAG | intron-variant | |
| rs1000091961 | -- | 34,901,630(+) | TTTTT(A/G)AATCA | intron-variant | |
| rs1000098142 | -- | 34,898,243(+) | GCAGA(G/T)GGTCA | intron-variant | |
| rs1000123959 | -- | 34,920,171(+) | GATGA(A/G)AAAAC | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2668318 | CNV | deletion | 23128226 |
| esv2749560 | CNV | deletion | 23290073 |
| esv2761865 | CNV | gain | 21179565 |
| esv28857 | CNV | loss | 19812545 |
| esv3569431 | CNV | gain | 25503493 |
| esv3636126 | CNV | loss | 21293372 |
| esv3636127 | CNV | gain | 21293372 |
| nsv1134428 | CNV | deletion | 24896259 |
| nsv457106 | CNV | gain | 19166990 |
| nsv507772 | OTHER | sequence alteration | 20534489 |
| nsv522411 | CNV | gain | 19592680 |
| nsv569153 | CNV | gain | 21841781 |
| nsv569154 | CNV | loss | 21841781 |
| nsv832967 | CNV | loss | 17160897 |
| nsv977699 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
3.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.51;
55.43% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for AQR Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- AQR
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for AQR Gene
Disorders for AQR Gene
Relevant External Links for AQR
No disorders were found for AQR Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for AQR Gene
Publications for AQR Gene
- A spliceosomal intron binding protein, IBP160, links Position- dependent assembly of intron-encoded box C/D snoRNP to pre-mRNA splicing. (PMID: 16949364) Hirose T. … Steitz J.A. (Mol. Cell 2006) 2 3 4 64
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
- Dengue hemorrhagic fever is associated with polymorphisms in JAK1. (PMID: 20588308) Silva L.K. … Teixeira M.G. (Eur. J. Hum. Genet. 2010) 3 46 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. (PMID: 11991638) Jurica M.S. … Moore M.J. (RNA 2002) 3 4 64
Products for AQR Gene
- Browse R&D Systems for Antibodies
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- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
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- Browse Cell Culture Products
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- Custom Antibody ServicesOriGene Antibodies for AQR
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for AQR
- Search Origene for MassSpec and Protein Over-expression Lysates for AQR
- Origene Custom Protein Services for AQR
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for AQR
- Browse OriGene Inhibitory RNA Products For AQR
- OriGene qPCR primer pairs for AQR
- OriGene CRISPR knockouts for AQR
- OriGene ORF clones in human for AQR
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For AQR
- GenScript: Next-day shipping cDNA ORF clone for AQR in any vector
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- GenScript: Design CRISPR guide RNA sequences for AQR
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
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- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for AQR
- Novus Biologicals proteins for AQR
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ViGene Biosciences adenoviral particle packaged cDNA for AQR gene
- ViGene Biosciences lentiviral particle packaged cDNA for AQR gene
- ViGene Biosciences ready-to-package AAV shRNAs for AQR gene
- Search ViGene Biosciences for AQR
- Cyagen custom Knockout/knockin (KOKI) mouse models for AQR
- VectorBuilder custom plasmid, inducible vectors for AQR
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AQR
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for AQR Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer