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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

AQR Gene

protein-coding   GIFtS: 53
GCID: GC15M035147

aquarius homolog (mouse)

 Explore 6 diseases affiliated with
AQR via our new
 Human Malady Compendium 
Biological research products
for AQR
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Aquarius Homolog (Mouse)1 2     IBP1602 3
FSAP1641     Functional Spliceosome-Associated Protein 1642
KIAA05601 3     Intron-Binding Protein Aquarius2
Intron-Binding Protein Of 160 KDa2 3     

External Ids:    HGNC: 295131   Entrez Gene: 97162   Ensembl: ENSG000000217767   OMIM: 6105485   UniProtKB: O603063   

Export aliases for AQR gene to outside databases

Previous GC identifers: GC15M030490 GC15M028043 GC15M032726 GC15M032863 GC15M032935 GC15M011994


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: AQR_HUMAN, O60306
Function: Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar
ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP,
splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of
pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40
nucleotides upstream of the branchpoint) during the late stages of splicing




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NC_018926.1  NT_010194.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the AQR gene promoter:
         TBP   AREB6   AML1a   NCX/Ncx   TFIID   FOXD1   CUTL1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAQR promoter sequence
   Search SABiosciences Chromatin IP Primers for AQR

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AQR


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q14   Ensembl cytogenetic band:  15q14   HGNC cytogenetic band: 15q13

AQR Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AQR gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M035147:  view genomic region     (about GC identifiers)

Start:
35,147,732 bp from pter      End:
35,262,040 bp from pter
Size:
114,309 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: AQR_HUMAN, O60306 (See protein sequence)
Recommended Name: Intron-binding protein aquarius  
Size: 1485 amino acids; 171295 Da
Subunit: Identified in the spliceosome C complex
Subcellular location: Nucleus. Note=Localizes to speckle-like regions of the nucleoplasm
Sequence caution: Sequence=BAA25486.3; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A0JP17 A5YKK3 Q2YDX9 Q6IRU8 Q6PIC8

Explore the universe of human proteins at neXtProt for AQR: NX_O60306

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O60306

  • AQR Protein expression data from MOPED and PaxDb:    About this image 
    AQR Protein Expression
    REFSEQ proteins: NP_055506.1  
    ENSEMBL proteins: 
     ENSP00000156471   ENSP00000445700   ENSP00000453278  

    Human Recombinant Protein Products for AQR: 
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    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for AQR

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005681spliceosomal complex ----
    GO:0071013catalytic step 2 spliceosome IDA11991638

    AQR for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for AQR


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    AQR for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR026300 CWF11_fam
     IPR024860 Aquarius

    Graphical View of Domain Structure for InterPro Entry O60306

    ProtoNet protein and cluster: O60306

    UniProtKB/Swiss-Prot: AQR_HUMAN, O60306
    Similarity: Belongs to the CWF11 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: AQR_HUMAN, O60306
    Function: Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar
    ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP,
    splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of
    pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40
    nucleotides upstream of the branchpoint) during the late stages of splicing

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0097157pre-mRNA intronic binding IEA--
         
    AQR for ontologies           About GeneDecksing


    Phenotypes:
         5 GenomeRNAi human phenotypes for AQR:
     Decreased influenza A virus in  Decreased viability  Decreased viability of wild-ty  Increased G2M DNA content 
     Increased gamma-H2AX phosphory 

         1 MGI mutant phenotype (inferred from 2 alleles(MGI details for Aqr):
     normal 

    AQR for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for AQR 

    miRNA
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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate AQR:
    hsa-miR-1303 hsa-miR-7-1* hsa-miR-7-2*
    SwitchGear 3'UTR luciferase reporter plasmidAQR 3' UTR sequence
    Inhib. RNA
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    Clone
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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AQR


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1mRNA Splicing - Major Pathway
    Spliceosome0.31

    Pathway sources
    See GeneCards unified pathways
    Show all pathways



    1         Kegg Pathway  (Kegg details for AQR):
        Spliceosome


    AQR for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AQR

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    5/567 Interacting proteins for AQR (O603062, 3 ENSP000001564714) via UniProtKB, MINT, STRING, and/or I2D (see all 567)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RBM4Q9BWF32, ENSP000003091664MINT-8337277 MINT-7945693 STRING: ENSP00000309166
    ZNF830Q96NB32, ENSP000003545184MINT-8337266 MINT-8332042 STRING: ENSP00000354518
    RBM22Q9NW642, ENSP000001998144MINT-8337002 STRING: ENSP00000199814
    PQBP1O608282, ENSP000003657474MINT-8336947 STRING: ENSP00000365747
    WDR77Q9BQA12, ENSP000002350904MINT-8337288 STRING: ENSP00000235090
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000398mRNA splicing, via spliceosome IC11991638

    AQR for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for AQR
    Search CenterWatch for drugs/clinical trials and news about AQR 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for AQR gene: 
    NM_014691.2  

    Unigene Cluster for AQR:

    Aquarius homolog (mouse)
    Hs.510958  [show with all ESTs]
    Unigene Representative Sequence: EF553519
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000156471(uc001ziv.3) ENST00000543879 ENST00000559090 ENST00000559767
    ENST00000560117 ENST00000558202

    miRNA
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    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat AQR
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate AQR:
    hsa-miR-1303 hsa-miR-7-1* hsa-miR-7-2*
    SwitchGear 3'UTR luciferase reporter plasmidAQR 3' UTR sequence
    Inhib. RNA
    Products:
         
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for AQR (see all 7)
    OriGene shRNA RFP: AQR
    OriGene siRNA: AQR
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    Sirion Biotech Custom design and validation of potent shRNA sequences against AQR 
    Clone
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AQR
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AQR

    Additional cDNA sequence: 

    AB011132.3 AK001173.1 AK291615.1 AK315815.1 BC027452.1 BC036913.2 BC070379.1 BC108262.1 
    BC127111.1 BC127112.1 EF553519.1 

    10 DOTS entries:

    DT.101984214  DT.451517  DT.92018129  DT.65284904  DT.121022589  DT.95323551  DT.121022606  DT.121022619 
    DT.121022626  DT.95360192 

    24/156 AceView cDNA sequences (see all 156):

    CF552371 AA343831 AU125182 AL701083 AA351172 BI761492 AA421031 AI138832 
    BI089220 CD721783 NM_014691 CR608508 BX282519 BM974504 AB011132 W04499 
    AI141109 AU132909 CD652467 CD654522 AL602168 BC036913 CB116098 BX281465 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for AQR (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^ 19 ^ 20 ^ 21 ^ 22 ^
    SP1:              -                                                                                                                 -                           
    SP2:              -                                                                                                                                             
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 23 ^ 24 ^ 25 ^ 26 ^ 27 ^ 28 ^ 29a · 29b ^ 30 ^ 31 ^ 32 ^ 33a · 33b ^ 34a · 34b ^ 35 ^ 36a · 36b · 36c · 36d
    SP1:              -                                                     -           -                                       
    SP2:              -                                                     -           -                                       
    SP3:                                                                                                                        
    SP4:                                                                                                                        
    SP5:                                                                                -                                       


    ECgene alternative splicing isoforms for AQR

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    AQR expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTTTGATCAC
    AQR Expression
    About this image
    See AQR Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for AQR

    SOURCE GeneReport for Unigene cluster: Hs.510958
        SABiosciences Custom PCR Arrays for AQR

    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AQR
    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for AQR gene from 8/32 species (see all 32)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves AQR1 aquarius homolog (mouse) 79.61(n)
    88.18(a)
      423296  XM_421216.3  XP_421216.3 
    lizard
    (Anolis carolinensis)
    Reptilia AQR6
    C4orf216
    (see all 3)
    --
    90(a)
    9(a)
    (see all 3)
    1 ↔ 1
    possible ortholog
    (see all 3)
    1(30369128-30425798)
    5(143005428-143031610)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.240672 Xenopus laevis transcribed sequences 75.37(n)    BU901034.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc636112 hypothetical protein MGC63611 73.58(n)   393436  BC055165.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG313681 CG31368 60.67(n)
    64.32(a)
      41437  NM_169439.3  NP_731647.3 
    worm
    (Caenorhabditis elegans)
    Secernentea emb-41 Protein EMB-4 55.1(n)
    54.52(a)
      180232  NM_075283.4  NP_507684.4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons EMB27651 intron-binding protein aquarius 55.71(n)
    51.01(a)
      818459  NM_179966.1  NP_850297.1 
    rice
    (Oryza sativa)
    Liliopsida Os.202882 Oryza sativa (japonica cultivar-group) cDNA clone0 more 70.95(n)    AK110991.1 


    ENSEMBL Gene Tree for AQR (if available)
    TreeFam Gene Tree for AQR (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for AQR gene
    ZNFX12  UPF12  C4orf212  

    AQR for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1836 NCBI SNPs in AQR are shown (see all 1836    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2002847401,2
    C--12102012(-) TTTAGA/GANNNN 1 -- int10--------
    rs352629221,2
    C--12104172(+) TGGCC-/TTTT  
            
    TTTTT
    1 -- int11Minor allele frequency- TTTT:0.00NA 2
    rs10553561,2
    C,F,O,A,H--35148102(-) CCACAA/GGGAGA 1 -- ds500125Minor allele frequency- G:0.29MN NA NS EA WA CSA 2668
    rs1831681331,2
    --35148134(+) AGGCAG/TAAAAC 1 -- ds50010--------
    rs1149981381,2
    F--35148231(+) CTTGCC/ACAGAT 1 -- ds50011Minor allele frequency- A:0.09WA 118
    rs172372141,2
    C,F--35148249(+) GCAGAG/ATCCTC 1 -- ds50014Minor allele frequency- A:0.02NA 262
    rs1471685901,2
    --35148337(+) TGGTG-/TG    
       GAGAA
    TGGAG
    1 -- ds50010--------
    rs746518001,2
    F--35148376(+) CTAATC/TCTGAG 1 -- ds50011Minor allele frequency- T:0.09WA 118
    rs1876102781,2
    --35148469(+) AAGGAA/GATGCA 1 -- ds50010--------
    rs1925742471,2
    --35148475(+) ATGCAC/TGTAAC 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for AQR (35147732 - 35262040 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for AQR
         1 CNV: 66771
         1 Indel: 87638

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    AQR for disorders           About GeneDecksing

    OMIM gene information: 610548    OMIM disorders: --

    6 diseases for AQR:    About MalaCards
    tick-borne encephalitis    louping ill    dengue hemorrhagic fever    hemorrhagic fever
    encephalitis    malaria

    1 disease from the University of Copenhagen DISEASES database for AQR:
    tick-borne encephalitis
    Human Genome Epidemiology (HuGE) Navigator: AQR (2 documents)

    Export disorders for AQR gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for AQR gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with AQR)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A spliceosomal intron binding protein, IBP160, links Position- dependent assembly of intron-encoded box C/D snoRNP to pre-mRNA splicing. (PubMed id 16949364)1, 2 Hirose T.... Steitz J.A. (2006)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. (PubMed id 11991638)1, 2 Jurica M.S.... Moore M.J. (2002)
    4. Aquarius, a novel gene isolated by gene trapping with an RNA-dependent RNA polymerase motif. (PubMed id 9626505)1, 3 Sam M....Bernstein A. (1998)
    5. Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9628581)1, 2 Nagase T....Ohara O. (1998)
    6. DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation. (PubMed id 22446626)1 Close P.... Svejstrup J.Q. (2012)
    7. Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
    8. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9716 HGNC: 29513 AceView: AQR Ensembl:ENSG00000021776 euGenes: HUgn9716
    ECgene: AQR Kegg: 9716 H-InvDB: AQR

    (According to HUGE)
    About This Section
    HUGE: KIAA0560

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for AQR Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for AQR gene:
    Search GeneIP for patents involving AQR

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 13 May 2013

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