External Ids for AQP5 Gene
Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13. [provided by RefSeq, Jul 2008]
GeneCards Summary for AQP5 Gene
AQP5 (Aquaporin 5) is a Protein Coding gene. Diseases associated with AQP5 include palmoplantar keratoderma, bothnian type and unna-thost palmoplantar keratoderma. Among its related pathways are Nanog in Mammalian ESC Pluripotency and Stabilization and expansion of the E-cadherin adherens junction. GO annotations related to this gene include water channel activity. An important paralog of this gene is AQP1.
UniProtKB/Swiss-Prot for AQP5 Gene
Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions