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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

AQP11 Gene

protein-coding   GIFtS: 48
GCID: GC11P077300

Aquaporin 11

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Aquaporin 111 2
AQPX12 3 5
AQP-112 3
aquaporin-112

External Ids:    HGNC: 199401   Entrez Gene: 2826792   Ensembl: ENSG000001783017   OMIM: 6099145   UniProtKB: Q8NBQ73   

Export aliases for AQP11 gene to outside databases

Previous GC identifers: GC11M078840 GC11P077523 GC11P077027 GC11P077028 GC11P076978 GC11P073599


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for AQP11 Gene: 
AQP11 (aquaporin 11) is a protein-coding gene. Diseases associated with AQP11 include background diabetic retinopathy, and oligohydramnios, and among its related super-pathways are Regulation of Water Balance by Renal Aquaporins and SLC-mediated transmembrane transport. GO annotations related to this gene include transporter activity and molecular_function. An important paralog of this gene is AQP12B.

UniProtKB/Swiss-Prot: AQP11_HUMAN, Q8NBQ7
Function: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NT_167190.1  NC_018922.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the AQP11 gene promoter:
         STAT5B   USF1   Sox5   XBP-1   MIF-1   C/EBPalpha   Max   USF-1   Pax-4a   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAQP11 promoter sequence
   Search SABiosciences Chromatin IP Primers for AQP11

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AQP11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q14.1   Ensembl cytogenetic band:  11q14.1   HGNC cytogenetic band: 11q13.5

AQP11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AQP11 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P077300:  view genomic region     (about GC identifiers)

Start:
77,300,436 bp from pter      End:
77,321,401 bp from pter
Size:
20,966 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: AQP11_HUMAN, Q8NBQ7 (See protein sequence)
Recommended Name: Aquaporin-11  
Size: 271 amino acids; 30203 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)

Explore the universe of human proteins at neXtProt for AQP11: NX_Q8NBQ7

Explore proteomics data for AQP11 at MOPED 

AQP11 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

AQP11 Protein Expression

REFSEQ proteins: NP_766627.1  
ENSEMBL proteins: 
 ENSP00000318770  
Reactome Protein details: Q8NBQ7
Human Recombinant Protein Products for AQP11: 
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OriGene Protein Over-expression Lysate for AQP11
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Novus Biologicals AQP11 Lysate
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates 
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for AQP11 

Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005737cytoplasm ----
GO:0005783endoplasmic reticulum IEA--
GO:0005829cytosol IEA--
GO:0005886plasma membrane TAS--
GO:0009986cell surface IDA16650285

AQP11 for ontologies           About GeneDecksing



AQP11 Antibody Products: 
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Search for Antibodies for AQP11 at Abcam
Cloud-Clone Corp. Antibodies for AQP11 
ThermoFisher Antibodies for AQP11
LSBio Antibodies in human, mouse, rat for AQP11 

Assay Products for AQP11: 
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GenScript Custom Assay Services for AQP11
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for AQP11 
Cloud-Clone Corp. CLIAs for AQP11


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
HGNC Gene Families: 
AQP: Ion channels / Aquaporins

4 InterPro protein domains:
 IPR016697 Aquaporin_11/12
 IPR023271 Aquaporin-like
 IPR023266 Aquaporin_11
 IPR000425 MIP

Graphical View of Domain Structure for InterPro Entry Q8NBQ7

ProtoNet protein and cluster: Q8NBQ7

1 Blocks protein domain: IPB000425 MIP family

UniProtKB/Swiss-Prot: AQP11_HUMAN, Q8NBQ7
Domain: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming
loop with the signature motif Asn-Pro-Ala (NPA)
Similarity: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily


AQP11 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: AQP11_HUMAN, Q8NBQ7
Function: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By
similarity)

     Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003674molecular_function ND--
GO:0005215transporter activity IEA--
GO:0015250water channel activity ----
     
AQP11 for ontologies           About GeneDecksing


Phenotypes:
     6 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Aqp11):
 cellular  growth/size  homeostasis/metabolism  liver/biliary system  mortality/aging 
 renal/urinary system 

AQP11 for phenotypes           About GeneDecksing

Animal Models:
     MGI mouse knock-out Aqp11tm1Lex for AQP11

   inGenious Targeting Laboratory - Custom generated mouse model solutions for AQP11 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for AQP11

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for AQP11 
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for AQP11 

miRNA
Products:
    
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat AQP11
8/36 QIAGEN miScript miRNA Assays for microRNAs that regulate AQP11 (see all 36):
hsa-miR-3607-3p hsa-miR-15a hsa-miR-503 hsa-miR-4267 hsa-miR-374c hsa-miR-424 hsa-miR-15b hsa-miR-1294
SwitchGear 3'UTR luciferase reporter plasmidAQP11 3' UTR sequence
Inhib. RNA
Products:
    
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for AQP11
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AQP11

Gene Editing
Products:
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Sirion Biotech Customized adenovirus for overexpression of AQP11

Clone
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OriGene ORF clones in mouse, rat for AQP11
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: AQP11 (NM_173039)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for AQP11
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AQP11
Sirion Biotech Customized lentivirus for stable overexpression of AQP11 
                     Customized lentivirus expression plasmids for stable overexpression of AQP11 

Cell Line
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GenScript Custom overexpressing Cell Line Services for AQP11
Search LifeMap BioReagents cell lines for AQP11
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AQP11


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for AQP11 About                                                                                                See pathways by source

SuperPathContained pathways About
1Regulation of Water Balance by Renal Aquaporins
Aquaporin-mediated transport0.84
2SLC-mediated transmembrane transport
Transmembrane transport of small molecules0.50
3Nanog in Mammalian ESC Pluripotency
eNOS Signaling0.48
4Passive Transport by Aquaporins
Passive Transport by Aquaporins

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways

1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for AQP11
    eNOS Signaling

3        Reactome Pathways for AQP11
    Transmembrane transport of small molecules
Aquaporin-mediated transport
Passive Transport by Aquaporins



AQP11 for pathways           About GeneDecksing

Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AQP11

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for AQP11 (ENSP000003187704) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
STAT5AENSP000003412084STRING: ENSP00000341208
About this table

Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0001822kidney development ----
GO:0006810transport ----
GO:0006811NOT ion transport IDA16650285
GO:0006833water transport TAS--
GO:0015793NOT glycerol transport IDA16650285

AQP11 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for AQP11

Search CenterWatch for drugs/clinical trials and news about AQP11

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for AQP11 gene: 
NM_173039.2  

Unigene Cluster for AQP11:

Aquaporin 11
Hs.503345  [show with all ESTs]
Unigene Representative Sequence: NM_173039
2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000528638 ENST00000313578(uc009yuu.3 uc001oyj.3)
miRNA
Products:
     
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat AQP11
8/36 QIAGEN miScript miRNA Assays for microRNAs that regulate AQP11 (see all 36):
hsa-miR-3607-3p hsa-miR-15a hsa-miR-503 hsa-miR-4267 hsa-miR-374c hsa-miR-424 hsa-miR-15b hsa-miR-1294
SwitchGear 3'UTR luciferase reporter plasmidAQP11 3' UTR sequence
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for AQP11
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AQP11
Clone
Products:
     
OriGene clones in human, mouse for AQP11 (see all 7)
OriGene ORF clones in mouse, rat for AQP11
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GenScript: all cDNA clones in your preferred vector: AQP11 (NM_173039)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for AQP11
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AQP11
Sirion Biotech Customized lentivirus for stable overexpression of AQP11 
                     Customized lentivirus expression plasmids for stable overexpression of AQP11 
Primer
Products:
    
OriGene qPCR primer pairs and template standards for AQP11
OriGene qSTAR qPCR primer pairs in human, mouse for AQP11
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat AQP11
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AQP11
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AQP11

Additional mRNA sequence: 

AB028147.1 AK075346.1 AK311096.1 BC040443.1 

3 DOTS entries:

DT.100018577  DT.97769364  DT.91755985 

24/29 AceView cDNA sequences (see all 29):

H92059 BC040443 AI261193 AA843769 AI886656 AK075346 NM_173039 AA322527 
AI807380 BG202356 AI371809 AI471857 BX101015 AW298217 AB028147 CA868496 
BQ025213 BG182704 AW901175 BG204427 BG192631 BF510172 W26419 BF510177 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

AQP11 expression in normal human tissues (normalized intensities)      AQP11 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
AQP11 Expression
About this image


AQP11 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database 
 5/3 selected tissues (see all 3) fully expand
 
 Ovary (Reproductive System)
         Human Ovarian Fibroblasts (HOF)   
 
 Kidney (Urinary System)
         Ureteric Bud
 
 Fibroblast (Uncategorized)
         Human Ovarian Fibroblasts (HOF)   

See AQP11 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for AQP11

SOURCE GeneReport for Unigene cluster: Hs.503345
    SABiosciences Custom PCR Arrays for AQP11
Primer
Products:
OriGene qPCR primer pairs and template standards for AQP11
OriGene qSTAR qPCR primer pairs in human, mouse for AQP11
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QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AQP11
QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AQP11
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AQP11

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for AQP11 gene from 5/11 species (see all 11)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Aqp111 , 5 aquaporin 111, 5 85.36(n)1
83.03(a)1
  7 (53.57 cM)5
663331  NM_175105.31  NP_780314.11 
 977263795 
chicken
(Gallus gallus)
Aves AQP111 aquaporin 11 56.61(n)
42.15(a)
  426725  XM_003640598.1  XP_003640646.1 
lizard
(Anolis carolinensis)
Reptilia AQP116
aquaporin 11
37(a)
1 ↔ 1
GL343337.1(750792-759810)
zebrafish
(Danio rerio)
Actinopterygii aqp111 aquaporin 11 49.1(n)
37.6(a)
  553476  XM_001921633.3  XP_001921668.2 
fruit fly
(Drosophila melanogaster)
Insecta AQP6
aquaporin
21(a)
1 → many
2R(9099910-9102001)


ENSEMBL Gene Tree for AQP11 (if available)
TreeFam Gene Tree for AQP11 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for AQP11 gene
AQP12B2  AQP12A2  
2 SIMAP similar genes for AQP11 using alignment to 1 protein entry:     AQP11_HUMAN:
AQP12A    AQP12B

AQP11 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/432 SNPs in AQP11 are shown (see all 432)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 11 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1118893881,2
C--77298815(+) TAGTCT/CCAGCT 1 -- us2k11Minor allele frequency- C:0.00CSA 1
rs1397273721,2
--77298855(+) TGAACC/GCGGGA 1 -- us2k10--------
rs1133778451,2
C--77298886(+) AGATCG/ACGCCA 1 -- us2k11Minor allele frequency- A:0.00CSA 1
rs1822739221,2
--77298917(+) CAGAGC/TGAGAC 1 -- us2k10--------
rs1861494701,2
--77298938(+) AAAAAA/TAATAA 1 -- us2k10--------
rs1892022261,2
C--77299000(+) AAGAGA/GAAAGG 1 -- us2k10--------
rs1166637561,2
F--77299007(+) AAGGTC/TTTGAT 1 -- us2k11Minor allele frequency- T:0.04WA 118
rs1815329541,2
C--77299277(+) TTATCC/TGCCTG 1 -- us2k10--------
rs1858900821,2
--77299351(+) GAATGC/TGGTGG 1 -- us2k10--------
rs1913847111,2
--77299357(+) GGTGGC/TAAGAG 1 -- us2k10--------

HapMap Linkage Disequilibrium report for AQP11 (77300436 - 77321401 bp)

Structural Variations
     Database of Genomic Variants (DGV) 1 variation for AQP11:    About this table     
Variant IDTypeSubtypePubMed ID
nsv468641CNV Gain19166990

SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing AQP11
DNA2.0 Custom Variant and Variant Library Synthesis for AQP11

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 609914    OMIM disorders: --

7 diseases for AQP11:    About MalaCards
background diabetic retinopathy    oligohydramnios    nephrogenic diabetes insipidus    diabetes insipidus
kidney disease    polycystic kidney disease    diabetic retinopathy


AQP11 for disorders           About GeneDecksing


Export disorders for AQP11 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for AQP11 gene, integrated from 9 sources (see all 17):
(articles sorted by number of sources associating them with AQP11)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Disruption of aquaporin-11 produces polycystic kidneys following vacuolization of the proximal tubule. (PubMed id 16107722)1, 3 Morishita Y....Ishibashi K. (2005)
  2. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  4. In silico study of human aquaporin AQP11 and AQP12 cha nnels. (PubMed id 23359558)1 Calvanese L....Oliva R. (2013)
  5. Weight loss after gastric bypass is associated with a variant at 15q26.1. (PubMed id 23643386)1 Hatoum I.J....Kaplan L.M. (2013)
  6. The NPC motif of aquaporin-11, unlike the NPA motif o f known aquaporins, is essential for full expression of molecular function. (PubMed id 21118806)1 Ikeda M....Ishibashi K. (2011)
  7. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)
  8. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
  9. Aquaporin-11: a channel protein lacking apparent transport function expressed in brain. (PubMed id 16650285)1 Gorelick D.A....Agre P. (2006)
  10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 282679 HGNC: 19940 AceView: AQP11 Ensembl:ENSG00000178301 euGenes: HUgn282679
ECgene: AQP11 H-InvDB: AQP11

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for AQP11 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for AQP11 gene:
Search GeneIP for patents involving AQP11

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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Category
(GIFtS: 73)
transforming growth factor, beta 1
GIFtS Group
The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

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