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APTR Gene(RNA Gene)

Alu-Mediated CDKN1A/P21 Transcriptional Regulator (Non-Protein Coding)

GCID:
GC07M077657
GIFtS:
17
Genes Participants
UDN Logo

Aliases for APTR Gene

Subcategory (RNA class) for APTR Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for APTR Gene

  • Alu-Mediated CDKN1A/P21 Transcriptional Regulator (Non-Protein Coding) 2 3 5
  • RSBN1L Antisense RNA 1 (Non-Protein Coding) 2 3
  • RSBN1L-AS1 3

External Ids for APTR Gene

Previous HGNC Symbols for APTR Gene

  • RSBN1L-AS1

Summaries for APTR Gene

GeneCards Summary for APTR Gene

APTR (Alu-Mediated CDKN1A/P21 Transcriptional Regulator (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for APTR Gene

Genomics for APTR Gene

Products:

  1. Regulatory Element

Regulatory Elements for APTR Gene

Enhancers for APTR Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07G077720 0.9 Ensembl ENCODE 51.5 -23.4 -23383 0.7 ZNF362 ZNF146 ZNF394 OSR2 ZSCAN21 ZFHX2 GLIS1 ZNF629 ZNF600 PRDM10 APTR RSBN1L TMEM60 PHTF2 PTPN12
GH07G077684 1 Ensembl ENCODE 41 +12.4 12389 1.9 CTCF MXI1 TEAD4 INSM2 MAX YY1 ZBTB48 SCRT2 ZNF10 HLF APTR PTPN12 PHTF2 TMEM60 RSBN1L GC07P077654
GH07G077695 1.1 ENCODE 36.9 -0.2 -249 4.4 HDGF PKNOX1 FOXA2 MLX ARNT AGO1 ZFP64 WRNIP1 ARID4B SIN3A APTR PMS2P9 TMEM60 DTX2P1 FAM185BP SPDYE18 PHTF2 PTPN12
GH07G077727 1 Ensembl ENCODE 38.5 -31.3 -31256 2.8 PKNOX1 TAL1 SIN3A TCF12 ZNF121 GATA3 FOXK2 NCOR1 NFE2 RFX1 APTR PTPN12 TMEM60
GH07G077569 1.5 FANTOM5 Ensembl ENCODE dbSUPER 25.3 +126.8 126813 2.1 CTCF HDGF PKNOX1 RAD21 ZNF316 HMBOX1 NFE2 EMSY ZBTB17 PTPN12 GSAP APTR FGL2 LOC105375363
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around APTR on UCSC Golden Path with GeneCards custom track

Promoters for APTR Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000214080 845 4201 HDGF PKNOX1 FOXA2 MLX ARNT AGO1 ZFP64 WRNIP1 ARID4B SIN3A

Genomic Location for APTR Gene

Chromosome:
7
Start:
77,657,660 bp from pter
End:
77,697,345 bp from pter
Size:
39,686 bases
Orientation:
Minus strand

Genomic View for APTR Gene

Genes around APTR on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
APTR Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for APTR Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for APTR Gene

Proteins for APTR Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for APTR Gene

No Post-translational modifications

No data available for DME Specific Peptides for APTR Gene

Domains & Families for APTR Gene

Gene Families for APTR Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with APTR: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for APTR Gene

Function for APTR Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Animal Model Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for APTR Gene

Localization for APTR Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for APTR Gene

Pathways & Interactions for APTR Gene

SuperPathways for APTR Gene

PathCards logo More details on SuperPathways for APTR
No Data Available

Interacting Proteins for APTR Gene

Gene Ontology (GO) - Biological Process for APTR Gene

None

No data available for Pathways by source and SIGNOR curated interactions for APTR Gene

Drugs & Compounds for APTR Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for APTR Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

mRNA/cDNA for APTR Gene

(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for APTR Gene

No ASD Table

Relevant External Links for APTR Gene

GeneLoc Exon Structure for
APTR
ECgene alternative splicing isoforms for
APTR

Expression for APTR Gene

Products:

  1. Primer

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for APTR Gene

mRNA expression in normal human tissues for APTR Gene
mRNA expression by GTEx for APTR Gene

NURSA nuclear receptor signaling pathways regulating expression of APTR Gene:

APTR
genes like me logo Genes that share expression patterns with APTR: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for APTR Gene

Orthologs for APTR Gene

Evolution for APTR Gene

ENSEMBL:
Gene Tree for APTR (if available)
TreeFam:
Gene Tree for APTR (if available)

No data available for Orthologs for APTR Gene

Paralogs for APTR Gene

No data available for Paralogs for APTR Gene

Variants for APTR Gene

Sequence variations from dbSNP and Humsavar for APTR Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1000181461 -- 77,672,179(+) GCATG(A/G)TGGCA intron-variant
rs1000339579 -- 77,675,818(+) AATCC(C/G)AGCAC intron-variant
rs1000350679 -- 77,686,586(+) TGAAT(A/C)TGAGG intron-variant
rs1000405551 -- 77,688,260(+) CAGAG(C/G)CTGCA intron-variant
rs1000487980 -- 77,686,395(+) CCGCC(A/C)CTGCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for APTR Gene

Variant ID Type Subtype PubMed ID
esv2657737 CNV deletion 23128226
esv2661869 CNV deletion 23128226
esv2675970 CNV deletion 23128226
esv2734703 CNV deletion 23290073
esv3613804 CNV loss 21293372
esv3613805 CNV loss 21293372
esv3613806 CNV loss 21293372
nsv1114979 CNV deletion 24896259
nsv831039 CNV gain 17160897

Relevant External Links for APTR Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
APTR

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for APTR Gene

Disorders for APTR Gene

Relevant External Links for APTR

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
APTR

No disorders were found for APTR Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for APTR Gene

Publications for APTR Gene

  1. A new lncRNA, APTR, associates with and represses the CDKN1A/p21 promoter by recruiting polycomb proteins. (PMID: 24748121) Negishi M. … Dutta A. (PLoS ONE 2014) 2 3 64

Products for APTR Gene

Sources for APTR Gene

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