Aliases for APOPT1 Gene
Aliases for APOPT1 Gene
External Ids for APOPT1 Gene
- HGNC: 20492
- Entrez Gene: 84334
- Ensembl: ENSG00000256053
- OMIM: 616003
- UniProtKB: Q96IL0
Previous HGNC Symbols for APOPT1 Gene
- C14orf153
Previous GeneCards Identifiers for APOPT1 Gene
- GC14P104032
Summaries for APOPT1 Gene
-
This gene encodes a protein that localizes to the mitochondria, where it stimulates the release of cytochrome c, thereby promoting programmed cell death. Mutations in this gene have been found in individuals with mitochondrial complex IV deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
GeneCards Summary for APOPT1 Gene
APOPT1 (Apoptogenic 1, Mitochondrial) is a Protein Coding gene. Diseases associated with APOPT1 include Non-Progressive Predominantly Posterior Cavitating Leukoencephalopathy With Peripheral Neuropathy and Mitochondrial Complex Iv Deficiency.
UniProtKB/Swiss-Prot for APOPT1 Gene
-
Plays a role in the regulation of apoptosis. Mediates mitochondria-induced cell death in vascular smooth muscle cells through the release of cytochrome c from mitochondria, followed by the activation of the caspase cascade.
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for APOPT1 Gene
Genomics for APOPT1 Gene
Regulatory Elements for APOPT1 Gene
Enhancers for APOPT1 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around APOPT1 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for APOPT1 Gene
- Chromosome:
- 14
- Start:
- 103,562,957 bp from pter
- End:
- 103,607,523 bp from pter
- Size:
- 44,567 bases
- Orientation:
- Plus strand
Genomic View for APOPT1 Gene
Genes around APOPT1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 14q32.33 by Ensembl
- 14q32.33 by Entrez Gene
- 14q32.33 by HGNC
APOPT1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for APOPT1 Gene
Proteins for APOPT1 Gene
-
Protein details for APOPT1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96IL0-APOP1_HUMAN
- Recommended name:
- Apoptogenic protein 1, mitochondrial
- Protein Accession:
- Q96IL0
- Q53G28
Protein attributes for APOPT1 Gene
- Size:
- 206 amino acids
- Molecular mass:
- 24153 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAH07412.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAD96812.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAD96823.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Post-translational modifications for APOPT1 Gene
Other Protein References for APOPT1 Gene
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for APOPT1
-
Abcam antibodies for APOPT1
- antibodies-online Antibodies for APOPT1: See all 2
- Search GeneTex for Antibodies for APOPT1
Protein Products
-
OriGene Purified Proteins for APOPT1
- Search Origene for MassSpec and Protein Over-expression Lysates for APOPT1
- Origene Custom Protein Services for APOPT1
- antibodies-online Proteins for APOPT1: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Proteins for APOPT1
Assay Products
No data available for DME Specific Peptides for APOPT1 Gene
Domains & Families for APOPT1 Gene
Suggested Antigen Peptide Sequences for APOPT1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q96IL0- Family:
-
- Belongs to the APOPT family.
No data available for Gene Families for APOPT1 Gene
Function for APOPT1 Gene
Molecular function for APOPT1 Gene
- UniProtKB/Swiss-Prot Function:
- Plays a role in the regulation of apoptosis. Mediates mitochondria-induced cell death in vascular smooth muscle cells through the release of cytochrome c from mitochondria, followed by the activation of the caspase cascade.
Phenotypes for APOPT1 Gene
- GenomeRNAi human phenotypes for APOPT1:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for APOPT1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for APOPT1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for APOPT1 gene
- Search ViGene Biosciences for APOPT1
CRISPR Products
-
OriGene CRISPR knockouts for APOPT1
-
Santa Cruz Biotechnology (SCBT) CRISPR for APOPT1
- GenScript: Design CRISPR guide RNA sequences for APOPT1
miRNA for APOPT1 Gene
- miRTarBase miRNAs that target APOPT1
-
- hsa-mir-615-3p (MIRT039923)
- hsa-mir-331-3p (MIRT043520)
- hsa-mir-5582-3p (MIRT444041)
- hsa-mir-548x-3p (MIRT444042)
- hsa-mir-548j-3p (MIRT444043)
- hsa-mir-548aq-3p (MIRT444044)
- hsa-mir-548am-3p (MIRT444045)
- hsa-mir-548aj-3p (MIRT444046)
- hsa-mir-548ah-3p (MIRT444047)
- hsa-mir-548ae-3p (MIRT444048)
- hsa-mir-7150 (MIRT573434)
- hsa-mir-3692-3p (MIRT573435)
- hsa-mir-548au-3p (MIRT573436)
- hsa-mir-449b-5p (MIRT573437)
- hsa-mir-449a (MIRT573438)
- hsa-mir-34c-5p (MIRT573439)
- hsa-mir-34a-5p (MIRT573440)
- hsa-mir-2115-5p (MIRT573441)
- hsa-mir-382-3p (MIRT573442)
- hsa-mir-640 (MIRT642608)
- hsa-mir-6778-3p (MIRT642609)
- hsa-mir-150-5p (MIRT642610)
- hsa-mir-7107-5p (MIRT642611)
- hsa-mir-1234-3p (MIRT642612)
- hsa-mir-186-3p (MIRT642613)
- hsa-mir-6513-3p (MIRT642614)
- hsa-mir-8079 (MIRT642615)
- hsa-mir-1245a (MIRT642616)
- hsa-mir-4284 (MIRT661277)
- hsa-mir-4772-3p (MIRT661278)
- hsa-mir-1307-3p (MIRT661279)
- hsa-mir-4638-5p (MIRT661280)
- hsa-mir-1304-3p (MIRT661281)
- hsa-mir-6741-3p (MIRT661282)
- hsa-mir-6890-3p (MIRT661283)
- hsa-mir-4655-5p (MIRT661284)
miRNA Products
- Search ViGene Biosciences for APOPT1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for APOPT1
- Browse OriGene Inhibitory RNA Products For APOPT1
-
ViGene Biosciences ready-to-package AAV shRNAs for APOPT1 gene
Clone Products
- Sino Biological Human cDNA Clone for APOPT1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for APOPT1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for APOPT1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for APOPT1
-
ViGene Biosciences adenoviral particle packaged cDNA for APOPT1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for APOPT1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for APOPT1 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for APOPT1 Gene
Localization for APOPT1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for APOPT1 Gene
- Mitochondrion.
| Compartment | Confidence |
|---|---|
| mitochondrion | 3 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005739 | mitochondrion | IBA | -- |
Pathways & Interactions for APOPT1 Gene
No Data Available
Interacting Proteins for APOPT1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006915 | apoptotic process | IEA | -- |
| GO:0034393 | positive regulation of smooth muscle cell apoptotic process | IEA | -- |
| GO:0043280 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | IEA,IBA | -- |
| GO:0090200 | positive regulation of release of cytochrome c from mitochondria | IEA,IBA | -- |
| GO:0097193 | intrinsic apoptotic signaling pathway | IBA,IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for APOPT1 Gene
Transcripts for APOPT1 Gene
mRNA/cDNA for APOPT1 Gene
- (4) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (140) Selected AceView cDNA sequences:
- (16) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for APOPT1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for APOPT1
-
Santa Cruz Biotechnology (SCBT) CRISPR for APOPT1
- GenScript: Design CRISPR guide RNA sequences for APOPT1
miRNA Products
- Search ViGene Biosciences for APOPT1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for APOPT1
- Browse OriGene Inhibitory RNA Products For APOPT1
-
ViGene Biosciences ready-to-package AAV shRNAs for APOPT1 gene
Clone Products
- Sino Biological Human cDNA Clone for APOPT1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for APOPT1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for APOPT1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for APOPT1 Gene
NURSA nuclear receptor signaling pathways regulating expression of APOPT1 Gene:
APOPT1SOURCE GeneReport for Unigene cluster for APOPT1 Gene:
Hs.598441Phenotype-based relationships between genes and organs from Gene ORGANizer for APOPT1 Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- digestive
- immune
- integumentary
- nervous
- respiratory
- skeletal muscle
- urinary
Organs:
Head and neck:
- brain
- cerebrospinal fluid
- cranial nerve
- ear
- eye
- eyelid
- face
- head
- meninges
- neck
Thorax:
- bronchus
- heart
- heart valve
- lung
- trachea
Abdomen:
- kidney
- liver
General:
- blood
- blood vessel
- coagulation system
- peripheral nervous system
- red blood cell
- skin
Primer Products
-
OriGene qPCR primer pairs for APOPT1
-
OriGene qPCR primer pairs and template standards for APOPT1
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Evidence on tissue expression from TISSUES for APOPT1 Gene
Orthologs for APOPT1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| dog (Canis familiaris) |
Mammalia | APOPT1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | APOPT1 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Apopt1 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | APOPT1 35 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Apopt1 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | APOPT1 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | APOPT1 34 35 |
|
||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | apopt1 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | apopt1 34 35 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG14806 35 |
|
OneToOne | |
| worm (Caenorhabditis elegans) |
Secernentea | Y39B6A.34 35 |
|
OneToOne |
- Species where no ortholog for APOPT1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chimpanzee (Pan troglodytes)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for APOPT1 Gene
(33) SIMAP similar genes for APOPT1 Gene using alignment to 7 proteins:
No data available for Paralogs for APOPT1 Gene
Variants for APOPT1 Gene
| SNP ID | Clin | Chr 14 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs587777784 | Pathogenic | 103,571,695(+) | ACCTT(C/G/T)GACCT | nc-transcript-variant, reference, stop-gained | |
| rs587777785 | Pathogenic | 103,571,622(+) | TTAAA(A/G)GTCTC | splice-acceptor-variant | |
| rs587777786 | Pathogenic | 103,571,813(+) | GACTT(C/T)TAGTA | nc-transcript-variant, reference, missense | |
| rs587777787 | Pathogenic | 103,574,116(+) | AAGAA(-/GAA)TTTAT | intron-variant, nc-transcript-variant, cds-indel | |
| rs35960830 | Likely benign | 103,571,723(+) | TGAAA(A/G)TGAAT | nc-transcript-variant, reference, missense |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3635599 | CNV | gain | 21293372 |
| nsv1054574 | CNV | loss | 25217958 |
| nsv1122931 | CNV | deletion | 24896259 |
| nsv1131165 | CNV | deletion | 24896259 |
| nsv566022 | CNV | loss | 21841781 |
| nsv832883 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
46.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.85;
74.00% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for APOPT1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for APOPT1 Gene
Disorders for APOPT1 Gene
(6) MalaCards diseases for APOPT1 Gene - From: OMIM, ClinVar, GeneTests, Orphanet, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| non-progressive predominantly posterior cavitating leukoencephalopathy with peripheral neuropathy |
|
|
| mitochondrial complex iv deficiency |
|
|
| human monocytic ehrlichiosis |
|
|
| leukodystrophy, adult-onset, autosomal dominant |
|
|
| ptosis, congenital |
|
|
Search APOPT1 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for APOPT1
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- APOPT1
No data available for UniProtKB/Swiss-Prot and Genatlas for APOPT1 Gene
Publications for APOPT1 Gene
- Akt activation prevents Apop-1-induced death of cells. (PMID: 18977203) Sun X. … Rakugi H. (Biochem. Biophys. Res. Commun. 2008) 2 3 64
- Apop-1, a novel protein inducing cyclophilin D-dependent but Bax/Bak-related channel-independent apoptosis. (PMID: 16782708) Yasuda O. … Ogihara T. (J. Biol. Chem. 2006) 2 3 64
- Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PMID: 16712791) Wang A.G. … Kim N.S. (Biochem. Biophys. Res. Commun. 2006) 3 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
Products for APOPT1 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for APOPT1
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for APOPT1
- Search Origene for MassSpec and Protein Over-expression Lysates for APOPT1
- Origene Custom Protein Services for APOPT1
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for APOPT1
- Browse OriGene Inhibitory RNA Products For APOPT1
- OriGene qPCR primer pairs and template standards for APOPT1
- OriGene qPCR primer pairs for APOPT1
- OriGene CRISPR knockouts for APOPT1
- OriGene ORF clones in human for APOPT1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For APOPT1
- GenScript: Next-day shipping cDNA ORF clone for APOPT1 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for APOPT1
- GenScript Custom Assay Services for APOPT1
- GenScript Custom overexpressing Cell Line Services for APOPT1
- GenScript: Design CRISPR guide RNA sequences for APOPT1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for APOPT1
- Sino Biological Human cDNA Clone for APOPT1
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- antibodies-online Antibodies for APOPT1: See all 2
- Search antibodies-online for kits
- antibodies-online Proteins for APOPT1: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Antibodies for APOPT1
- Search GeneTex for Proteins for APOPT1
- ViGene Biosciences adenoviral particle packaged cDNA for APOPT1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for APOPT1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for APOPT1 gene
- Search ViGene Biosciences for APOPT1
- Horizon Cell Lines for APOPT1
- Cyagen custom Knockout/knockin (KOKI) mouse models for APOPT1
- VectorBuilder custom plasmid, inducible vectors for APOPT1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for APOPT1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for APOPT1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer