Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

APOL5 Gene

protein-coding GIFtS: 54
GCID: GC22P036113

apolipoprotein L, 5

Explore 1 disease affiliated with
APOL5 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Apolipoprotein L, 5¹ ²
APOLV¹ ²
Apolipoprotein L-V² ³
APOL-V²
Apolipoprotein L5²
ApoL-V³

External Ids:	HGNC: 14869¹	Entrez Gene: 80831²	Ensembl: ENSG00000128313⁷	OMIM: 607255⁵	UniProtKB: Q9BWW9³

Export aliases for APOL5 gene to outside databases

Previous GC identifers: GC22P032757 GC22P034385 GC22P034438 GC22P019076

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for APOL5:

This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may

affect the movement of lipids or allow the binding of lipids to organelles. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: APOL5_HUMAN, Q9BWW9

Function: May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000022.10 NC_018933.1 NT_011520.12

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the APOL5 gene promoter:
HEN1 c-Myb FOXD1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: APOL5 promoter sequence

Search SABiosciences Chromatin IP Primers for APOL5

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat APOL5

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q12.3 Ensembl cytogenetic band: 22q12.3 HGNC cytogenetic band: 22q12.3

APOL5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
APOL5 gene location

GeneLoc information about chromosome 22 GeneLoc Exon Structure

GeneLoc location for GC22P036113: view genomic region (about GC identifiers)

Start:	36,113,919 bp from pter	End:	36,125,530 bp from pter
Size:	11,612 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: APOL5_HUMAN, Q9BWW9 (See protein sequence)

Recommended Name: Apolipoprotein L5

Size: 433 amino acids; 47044 Da

Subcellular location: Cytoplasm (Probable)

Secondary accessions: Q5TFL9 Q9UGW5

Explore the universe of human proteins at neXtProt for APOL5: NX_Q9BWW9

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9BWW9

APOL5 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_085145.1

ENSEMBL proteins:

ENSP00000249044

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells Browse OriGene Protein Over-expression Lysates OriGene Custom Protein Services for APOL5
	GenScript Custom Purified and Recombinant Proteins Services for APOL5
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for APOL5

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005575	cellular_component	ND	--
GO:0005576	extracellular region	IEA	--
GO:0005737	cytoplasm	IEA	--

APOL5 for ontologies About GeneDecksing

APOL5 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	OriGene Antibodies (see all 2): APOL5 OriGene Custom Antibody Services for APOL5
	GenScript Custom Superior Antibodies Services for APOL5
	Novus Biologicals APOL5 Antibodies
	Abcam antibodies for APOL5
	Uscn Antibodies for APOL5
	ThermoFisher Antibodies for APOL5

Assay Products for APOL5:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for APOL5
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for APOL5

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

APOL5 for domains About GeneDecksing

1 InterPro domain/family:

IPR008405 ApoL

Graphical View of Domain Structure for InterPro Entry Q9BWW9

ProtoNet protein and cluster: Q9BWW9

1 Blocks protein family: IPB008405 Apolipoprotein L

UniProtKB/Swiss-Prot: APOL5_HUMAN, Q9BWW9

Similarity: Belongs to the apolipoprotein L family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: APOL5_HUMAN, Q9BWW9

Function: May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat APOL5
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate APOL5
		SwitchGear 3'UTR luciferase reporter plasmid: APOL5 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for APOL5 (see all 4) OriGene shRNA RFP: APOL5 OriGene siRNA: APOL5
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat APOL5

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for APOL5

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for APOL5 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for APOL5 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: APOL5 (NM_030642)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for APOL5
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat APOL5

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for APOL5
		Search LifeMap BioReagents cell lines for APOL5

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for APOL5

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008035	high-density lipoprotein particle binding	NAS	11374903
GO:0008289	lipid binding	IEA	--

APOL5 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for APOL5:

Decreased viability with pacli

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF)

Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF)

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

1 GeneGo (Thomson Reuters) Pathway for APOL5

Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF)

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for APOL5

STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

5/7 Interacting proteins for APOL5 (Q9BWW9^{1, 2, 3} ENSP00000249044⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 7)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ABL1	P00519¹^,²^,³, ENSP00000361423⁴	EBI-1753592,EBI-375543 MINT-8110033 I2D: score=3 STRING: ENSP00000361423
FYN	P06241¹^,²^,³, ENSP00000357656⁴	EBI-1753592,EBI-515315 MINT-8110923 I2D: score=3 STRING: ENSP00000357656
PIK3R1	P27986¹^,²^,³, ENSP00000274335⁴	EBI-1753592,EBI-79464 MINT-8111691 I2D: score=3 STRING: ENSP00000274335
CRK	P46108¹^,³, ENSP00000300574⁴	EBI-1753592,EBI-886 I2D: score=2 STRING: ENSP00000300574
SRC	P12931¹^,²^,³, ENSP00000350941⁴	EBI-1753592,EBI-621482 MINT-8112903 I2D: score=3 STRING: ENSP00000350941

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006629	lipid metabolic process	NAS	11374903
GO:0006869	lipid transport	IEA	--
GO:0042157	lipoprotein metabolic process	IEA	--

APOL5 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for APOL5
Search CenterWatch for drugs/clinical trials and news about APOL5

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for APOL5 gene:

NM_030642.1

Unigene Cluster for APOL5:

Apolipoprotein L, 5

Hs.326561 [show with all ESTs]

Unigene Representative Sequence: NM_030642

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000249044(uc003aof.3)

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat APOL5
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate APOL5
		SwitchGear 3'UTR luciferase reporter plasmid: APOL5 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for APOL5 (see all 4) OriGene shRNA RFP: APOL5 OriGene siRNA: APOL5
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat APOL5

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for APOL5 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for APOL5 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: APOL5 (NM_030642)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for APOL5
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat APOL5

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for APOL5 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat APOL5
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat APOL5
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat APOL5

Additional cDNA sequence: AY014878.1

2 DOTS entries:

DT.65287960 DT.40270399

9 AceView cDNA sequences:

AY014878 AL045459 H55142 NM_030642 AI277636 BX280778 AW369416 AL045458

AI740692

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

APOL5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGCAGCTTCC

About this image

APOL5 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Bone

Zeugopod Growth Plate

Bone

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See APOL5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for APOL5

SOURCE GeneReport for Unigene cluster: Hs.326561

UniProtKB/Swiss-Prot: APOL5_HUMAN, Q9BWW9

Tissue specificity: Low level of expression; detected in uterus, testis, skeletal muscle and stomach

SABiosciences Expression via Pathway-Focused PCR Array including APOL5:

Lipoprotein Signaling & Cholesterol Metabolism in human mouse rat

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for APOL5 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat APOL5
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat APOL5
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat APOL5

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for APOL5

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for APOL5 gene from 1/5 species (see all 5) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
lizard (Anolis carolinensis)	Reptilia	-- --	--	51(a) 37(a)	many ↔ many many ↔ many	5(21779188-21779424) 5(21749807-21750637)

ENSEMBL Gene Tree for APOL5 (if available)
TreeFam Gene Tree for APOL5 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for APOL5 gene

APOL4² APOL6² APOL2² APOL1² APOL3² APOLD1²

2 SIMAP similar genes for APOL5 using alignment to 1 protein entry: APOL5_HUMAN:

APOL6 ApoL6

APOL5 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 22 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs192247215^1,2		--	36111998(+)	`TATAAA/CAAAAA`	1	--	us2k¹		0	--	--	--	--
rs183402436^1,2		--	36112077(+)	`TTTCTA/GCATCC`	1	--	us2k¹		0	--	--	--	--
rs186580247^1,2		--	36112225(+)	`TGGCAA/GCATTC`	1	--	us2k¹		0	--	--	--	--
rs75779978^1,2	C	--	36112283(+)	`TAATGA/CATAAT`	1	--	us2k¹		0	--	--	--	--
rs113900883^1,2	C,	--	36112477(+)	`ACCACG/ACCTGG`	1	--	us2k¹		1		WA	2
rs117385964^1,2	F,	--	36112681(+)	`AAAAGT/GGCAAA`	1	--	us2k¹		1		EA	120
rs11387924^1,2	C,	--	36112797(+)	`TACTT-/AAAAAA`	1	--	us2k¹		0	--	--	--	--
rs33920862^1,2	C	--	36112798(+)	`ACTTAA/-AAAAA`	1	--	us2k¹		1		NA	2
rs4821434^1,2	C	--	36112879(+)	`TCTAGG/TTCAGT`	1	--	us2k¹		1		NA	2
rs59375100^1,2	C	--	36112958(+)	`AAACAACA/-GTCCC`	1	--	us2k¹		1		NA	2

HapMap Linkage Disequilibrium report for APOL5 (36113919 - 36125530 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for APOL5
1 CNV: 36021

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing APOL5

DNA2.0 Custom Variant and Variant Library Synthesis for APOL5

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

APOL5 for disorders           About GeneDecksing

OMIM gene information: 607255    OMIM disorders: --

1 disease for APOL5:    About MalaCards

cholesterol

Human Genome Epidemiology (HuGE) Navigator: APOL5 (3 documents)

Export disorders for APOL5 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for APOL5 gene integrated from 9 sources:
(articles sorted by number of sources associating them with APOL5)

Utopia: connect your pdf to the dynamic
world of online information

The human apolipoprotein L gene cluster: identification, classification, and sites of distribution. (PubMed id 11374903)^{1, 2, 3} Page N.M....Lowry P.J. (2001)
The DNA sequence of human chromosome 22. (PubMed id 10591208)^{1, 2} Dunham I....O'Brien K.P. (1999)
Genetic associations of brain structural networks in schizophrenia: a preliminary study. (PubMed id 20691427)¹ Jagannathan K....Pearlson G.D. (2010)
Physiogenomic analysis of statin-treated patients: do main-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? (PubMed id 20602615)¹ RuaA+o G....Wu A.H. (2010)
Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. (PubMed id 17474147)¹ Wu C....Li S.S. (2007)
Embryo lipoproteins and yolk lipovitellin consumption during embryogenesis in Macrobrachium borellii (Crustacea: Palaemonidae). (PubMed id 18721894)⁹ Garcia F....Heras H. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 80831	HGNC: 14869	AceView: APOL5	Ensembl:ENSG00000128313	euGenes: HUgn80831
ECgene: APOL5	H-InvDB: APOL5

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for APOL5	Pharmacogenomics, SNPs, Pathways

Intellectual Property for APOL5 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for APOL5 gene:
Search GeneIP for patents involving APOL5

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	OriGene Antibodies for APOL5		OriGene shRNA RFP for APOL5
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for APOL5		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for APOL5
	Browse OriGene Protein Over-expression Lysates		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for APOL5		Browse 3'-UTR reporter clones for miRNA target validation
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for APOL5		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for APOL5
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for APOL5		OriGene Custom Protein Services for APOL5
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat APOL5
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing APOL5
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat APOL5
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat APOL5
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat APOL5
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat APOL5

	GenScript Custom Purified and Recombinant Proteins Services for APOL5		GenScript cDNA clones with any tag delivered in your preferred vector for APOL5
	GenScript Custom Assay Services for APOL5		GenScript Custom Superior Antibodies Services for APOL5
	GenScript Custom overexpressing Cell Line Services for APOL5		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in APOL5 promoter
	Search Chromatin IP Primers for APOL5
	RT² qPCR Primer Assay in human, mouse / rat APOL5
	Search GNC Networks for APOL5
	SABiosciences PCR Arrays including human, mouse, rat APOL5

Search Tocris compounds for APOL5

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	APOL5 antibodies

	Antibodies for APOL5
	See all of Abcam's Antibodies, Kits and Proteins for APOL5
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

APOL5 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for APOL5

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for APOL5

	SwitchGear 3'UTR luciferase reporter plasmids for APOL5
	SwitchGear Promoter luciferase reporter plasmids for APOL5

ThermoFisher Antibodies for APOL5

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat APOL5

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes APOL5 gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4

Advanced Search

Export list of displayed genes

APOL5 Gene

apolipoprotein L, 5

Aliases
for APOL5 gene

Summaries
for APOL5 gene

Genomic Views
for APOL5 gene

Proteins
for APOL5 gene

Protein Domains /
Families
for APOL5 gene

Function
for APOL5 gene

Pathways & Interactions
for APOL5 gene

Drugs & Compounds
for APOL5 gene

Transcripts
for APOL5 gene

Expression
for APOL5 gene

Orthologs
for APOL5 gene

Paralogs
for APOL5 gene

Genomic Variants
for APOL5 gene

Disorders / Diseases
for APOL5 gene

Publications
for APOL5 gene

External Searches for APOL5 gene

Genome Databases showing APOL5 gene

Other Databases showing APOL5 gene

Specialized Databases showing APOL5 gene

Intellectual Property
for APOL5 gene

Products
for APOL5 gene

View Random Gene

Advanced Search

Export list of displayed genes

APOL5 Gene

apolipoprotein L, 5

Aliasesfor APOL5 gene

Summariesfor APOL5 gene

Genomic Viewsfor APOL5 gene

Proteinsfor APOL5 gene

Protein Domains /Familiesfor APOL5 gene

Functionfor APOL5 gene

Pathways & Interactionsfor APOL5 gene

Drugs & Compoundsfor APOL5 gene

Transcriptsfor APOL5 gene

Expression for APOL5 gene

Orthologsfor APOL5 gene

Paralogsfor APOL5 gene

Genomic Variantsfor APOL5 gene

Disorders / Diseasesfor APOL5 gene

Publicationsfor APOL5 gene

External Searches for APOL5 gene

Genome Databases showing APOL5 gene

Other Databases showing APOL5 gene

Specialized Databases showing APOL5 gene

Intellectual Propertyfor APOL5 gene

Productsfor APOL5 gene

View Random Gene

Aliases
for APOL5 gene

Summaries
for APOL5 gene

Genomic Views
for APOL5 gene

Proteins
for APOL5 gene

Protein Domains /
Families
for APOL5 gene

Function
for APOL5 gene

Pathways & Interactions
for APOL5 gene

Drugs & Compounds
for APOL5 gene

Transcripts
for APOL5 gene

Expression
for APOL5 gene

Orthologs
for APOL5 gene

Paralogs
for APOL5 gene

Genomic Variants
for APOL5 gene

Disorders / Diseases
for APOL5 gene

Publications
for APOL5 gene

Intellectual Property
for APOL5 gene

Products
for APOL5 gene