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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

APOL2 Gene

protein-coding   GIFtS: 56
GCID: GC22M036622

Apolipoprotein L, 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Apolipoprotein L, 21 2
Apolipoprotein L-II1 2 3
APOL-II2
APOL32
Apolipoprotein L22
ApoL-II3

External Ids:    HGNC: 6191   Entrez Gene: 237802   Ensembl: ENSG000001283357   OMIM: 6072525   UniProtKB: Q9BQE53   

Export aliases for APOL2 gene to outside databases

Previous GC identifers: GC22M033265 GC22M034894 GC22M034946 GC22M019590


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for APOL2 Gene:
This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it
may affect the movement of lipids or allow the binding of lipids to organelles. Two transcript variants encoding
the same protein have been found for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for APOL2 Gene: 
APOL2 (apolipoprotein L, 2) is a protein-coding gene. Diseases associated with APOL2 include phencyclidine abuse, and peritoneal carcinoma. GO annotations related to this gene include high-density lipoprotein particle binding and receptor binding. An important paralog of this gene is APOL4.

UniProtKB/Swiss-Prot: APOL2_HUMAN, Q9BQE5
Function: May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles

Gene Wiki entry for APOL2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000022.10  NT_011520.12  NC_018933.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the APOL2 gene promoter:
         Bach1   GR   RREB-1   GR-beta   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): APOL2 promoter sequence
   Search SABiosciences Chromatin IP Primers for APOL2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat APOL2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q12   Ensembl cytogenetic band:  22q12.3   HGNC cytogenetic band: 22q12.3

APOL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
APOL2 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22M036622:  view genomic region     (about GC identifiers)

Start:
36,622,255 bp from pter      End:
36,636,000 bp from pter
Size:
13,746 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: APOL2_HUMAN, Q9BQE5 (See protein sequence)
Recommended Name: Apolipoprotein L2  
Size: 337 amino acids; 37092 Da
Subcellular location: Cytoplasm (Probable)
Sequence caution: Sequence=BAD92227.1; Type=Erroneous initiation;
Secondary accessions: B0QYK7 O95915 Q59GW9 Q5TH96 Q969T6 Q9BT28 Q9UGT1 Q9UH10

Explore the universe of human proteins at neXtProt for APOL2: NX_Q9BQE5

Explore proteomics data for APOL2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BQE5

  • APOL2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    APOL2 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_112092.1  NP_663612.1  

    ENSEMBL proteins: 
     ENSP00000351292   ENSP00000249066   ENSP00000403153   ENSP00000431231   ENSP00000400486  

    Human Recombinant Protein Products for APOL2: 
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    Novus Biologicals APOL2 Protein
    Novus Biologicals APOL2 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for APOL2 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0005789endoplasmic reticulum membrane NAS11374903

    APOL2 for ontologies           About GeneDecksing



    APOL2 Antibody Products: 
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    Cloud-Clone Corp. CLIAs for APOL2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    APOLIPO: Apolipoproteins

    1 InterPro protein domain:
     IPR008405 ApoL

    Graphical View of Domain Structure for InterPro Entry Q9BQE5

    ProtoNet protein and cluster: Q9BQE5

    1 Blocks protein domain: IPB008405 Apolipoprotein L

    UniProtKB/Swiss-Prot: APOL2_HUMAN, Q9BQE5
    Similarity: Belongs to the apolipoprotein L family


    APOL2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: APOL2_HUMAN, Q9BQE5
    Function: May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles

         Genatlas biochemistry entry for APOL2:
    apolipoprotein L,2

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005102receptor binding NAS11374903
    GO:0008035high-density lipoprotein particle binding NAS11374903
    GO:0008289lipid binding NAS11374903
         
    APOL2 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for APOL2:
     Decreased Salmonella enterica  

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for APOL2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for APOL2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for APOL2 
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    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat APOL2
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    SwitchGear 3'UTR luciferase reporter plasmidAPOL2 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
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                         Customized lentivirus expression plasmids for stable overexpression of APOL2 

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for APOL2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for APOL2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF)
    Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF)

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for APOL2
        Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF)


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for APOL2

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for APOL2 (Q9BQE53 ENSP000002490664) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARP102753, ENSP000003638224I2D: score=1 STRING: ENSP00000363822
    PACSIN1Q9BY113I2D: score=2 
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006629lipid metabolic process NAS11374903
    GO:0006869lipid transport NAS11374903
    GO:0006953acute-phase response NAS11374903
    GO:0007275multicellular organismal development NAS11374903
    GO:0008203cholesterol metabolic process NAS11374903

    APOL2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for APOL2

    Search CenterWatch for drugs/clinical trials and news about APOL2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for APOL2 gene (2 alternative transcripts): 
    NM_030882.2  NM_145637.1  

    Unigene Cluster for APOL2:

    Apolipoprotein L, 2
    Hs.474740  [show with all ESTs]
    Unigene Representative Sequence: AF324224
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000358502(uc011amm.2 uc003aoz.3) ENST00000249066(uc003apa.3)
    ENST00000451256 ENST00000529194 ENST00000454728 ENST00000476579 ENST00000489186
    ENST00000473549 ENST00000484830
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat APOL2
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate APOL2
    SwitchGear 3'UTR luciferase reporter plasmidAPOL2 3' UTR sequence
    Inhib. RNA
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    Browse for Gene Knock-down Tools from EMD Millipore
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    GenScript: all cDNA clones in your preferred vector (see all 2): APOL2 (NM_030882)
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat APOL2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat APOL2

    Additional mRNA sequence: 

    AB208990.1 AF305225.1 AF305429.1 AF324223.1 AF324224.1 AK056938.1 AK092839.1 AK303978.1 
    BC004395.1 

    13 DOTS entries:

    DT.91938360  DT.40299557  DT.92008485  DT.427943  DT.95102291  DT.95198024  DT.97797054  DT.70101552 
    DT.100784675  DT.120666326  DT.91852499  DT.95101152  DT.99938944 

    24/164 AceView cDNA sequences (see all 164):

    CB125020 BF915103 BI547539 BU584416 CD632856 BU584139 BX432248 BU517088 
    BQ948529 BU677850 AL599525 NM_145637 NM_030882 BU584676 AL709165 BU584681 
    AU279422 R80434 BU522058 BX115911 BQ688259 CB108991 AI082211 BU584522 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for APOL2 (see all 10)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e ^ 3a · 3b ^ 4a · 4b · 4c · 4d · 4e · 4f · 4g ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b · 10c
    SP1:                                      -     -     -     -     -     -     -     -     -     -                       -                                 
    SP2:                                      -     -     -     -           -     -     -     -     -     -                 -                                 
    SP3:        -     -     -                 -     -     -     -     -     -     -     -     -     -     -                 -                                 
    SP4:                                      -     -     -     -     -     -     -     -     -     -     -                 -                                 
    SP5:                                                  -     -     -     -     -     -     -     -     -                 -                                 


    ECgene alternative splicing isoforms for APOL2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    APOL2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    APOL2 Expression
    About this image


    See APOL2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for APOL2

    SOURCE GeneReport for Unigene cluster: Hs.474740

    UniProtKB/Swiss-Prot: APOL2_HUMAN, Q9BQE5
    Tissue specificity: Widely expressed; the highest levels are found in lung, thymus, pancreas, placenta, adult
    brain and prostate; also detected in spleen, liver, kidney, colon, small intestine, uterus, spinal cord, adrenal
    gland, salivary gland, trachea, mammary gland, skeletal muscle, testis and fetal brain and liver

        SABiosciences Expression via Pathway-Focused PCR Arrays including APOL2: 
              Lipoprotein Signaling & Cholesterol Metabolism in human mouse rat
              Inflammatory Response & Autoimmunity 384HT in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for APOL2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for APOL2 gene from 3/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Apol81 , 5 apolipoprotein L 81, 5 64.73(n)1
    45.57(a)1
      15 (36.79 cM)5
    2395521  NM_001081970.11  NP_001075439.11 
     777486135 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    44(a)
    29(a)
    many ↔ many
    many ↔ many
    5(21779188-21779424)
    5(21745647-21750643)
    zebrafish
    (Danio rerio)
    Actinopterygii APOL26
    apolipoprotein L, 2
    12(a)
    1 → many
    3(29825427-29839518)


    ENSEMBL Gene Tree for APOL2 (if available)
    TreeFam Gene Tree for APOL2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for APOL2 gene
    APOL42  APOL62  APOL52  APOL12  APOL32  
    5 SIMAP similar genes for APOL2 using alignment to 4 protein entries:     APOL2_HUMAN (see all proteins):
    APOL1    APOL3    APOL4    APOL6    ApoL6

    APOL2 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for APOL2
    PGOHUM00000246323 PGOHUM00000250341


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/487 SNPs in APOL2 are shown (see all 487)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs117036141,2
    C,F,A,H--19590826(+) GGGGGG/CGGGTC 2 -- ut31 ese310Minor allele frequency- C:0.10EA NS WA NA CSA 635
    rs1501996151,2
    --20543206(+) AGGTTA/TAGTCA 2 -- ds50010--------
    rs1843584631,2
    --20543253(+) CAAAGG/TCACAG 2 -- ds50010--------
    rs1897274451,2
    --20543256(+) AGTCAC/TAGCCA 2 -- ds50010--------
    rs1172148701,2
    F--20543268(+) CAGTCA/TGTGCT 2 -- ds50011Minor allele frequency- T:0.01NA 120
    rs1131928711,2
    C,F--20543357(+) CAGCTG/TATGAG 2 -- ds50012Minor allele frequency- T:0.05CSA WA 120
    rs1458423231,2
    C--20543432(+) TCAAGC/GTTCCT 2 -- ds50010--------
    rs22695971,2
    C,F,H--20543610(+) CCACCA/GTCACC 2 -- ds50013Minor allele frequency- G:0.04EA NA CSA 1315
    rs1812483631,2
    --20543627(+) ACGAGA/CAAAAC 2 -- ds50010--------
    rs1858039151,2
    --20543646(+) GATGGC/TCCCCA 2 -- ds50010--------

    HapMap Linkage Disequilibrium report for APOL2 (36622255 - 36636000 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for APOL2:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv1003985CNV Deletion20482838
    nsv834185CNV Loss17160897
    nsv915006CNV Loss21882294
    nsv522931CNV Gain19592680
    esv7844OTHER Inversion19470904

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing APOL2
    DNA2.0 Custom Variant and Variant Library Synthesis for APOL2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607252   
    OMIM disorders: 181500  
    6 diseases for APOL2:    About MalaCards
    phencyclidine abuse    peritoneal carcinoma    peritonitis    velocardiofacial syndrome
    schizophrenia    prostatitis

    1 disease from the University of Copenhagen DISEASES database for APOL2:
    Peritoneal carcinoma

    APOL2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): APOL2
    Human Genome Epidemiology (HuGE) Navigator: APOL2 (3 documents)

    Export disorders for APOL2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for APOL2 gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with APOL2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The human apolipoprotein L gene cluster: identification, classification, and sites of distribution. (PubMed id 11374903)1, 2, 3 Page N.M....Lowry P.J. (2001)
    2. The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2, 3 Dunham I....O'Brien K.P. (1999)
    3. Apolipoprotein L gene family: tissue-specific expression, splicing, promoter regions; discovery of a new gene. (PubMed id 11290834)1, 2, 9 Duchateau P.N.... Kane J.P. (2001)
    4. Physiogenomic analysis of statin-treated patients: do main-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? (PubMed id 20602615)1, 4 RuaA+o G....Wu A.H. (2010)
    5. Association of SNPs and haplotypes in APOL1, 2 and 4 with schizophrenia. (PubMed id 18632255)1, 4 Takahashi S....Tsuang M.T. (2008)
    6. Investigation of the apolipoprotein-L (APOL) gene family and schizophrenia using a novel DNA pooling strategy for public database SNPs. (PubMed id 15949655)1, 4 McGhee K.A....Corvin A. (2005)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    9. The apolipoprotein L gene cluster has emerged recently in evolution and is expressed in human vascular tissue. (PubMed id 11944986)1, 2 Monajemi H.... Horrevoets A.J.G. (2002)
    10. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23780 HGNC: 619 AceView: APOL2 Ensembl:ENSG00000128335 euGenes: HUgn23780
    ECgene: APOL2 H-InvDB: APOL2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for APOL2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for APOL2 gene:
    Search GeneIP for patents involving APOL2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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