Aliases for APOL2 Gene
Aliases for APOL2 Gene
External Ids for APOL2 Gene
- HGNC: 619
- Entrez Gene: 23780
- Ensembl: ENSG00000128335
- OMIM: 607252
- UniProtKB: Q9BQE5
Previous GeneCards Identifiers for APOL2 Gene
- GC22M033265
- GC22M034894
- GC22M034946
- GC22M036622
- GC22M019590
Summaries for APOL2 Gene
-
This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for APOL2 Gene
APOL2 (Apolipoprotein L2) is a Protein Coding gene. Diseases associated with APOL2 include Schizophrenia and Phencyclidine Abuse. Among its related pathways are Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF). GO annotations related to this gene include receptor binding and high-density lipoprotein particle binding. An important paralog of this gene is APOL1.
UniProtKB/Swiss-Prot for APOL2 Gene
-
May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for APOL2 Gene
Genomics for APOL2 Gene
Regulatory Elements for APOL2 Gene
Enhancers for APOL2 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH22G036449 | 1.7 | FANTOM5 ENCODE dbSUPER | 9.3 | -212.9 | -212898 | 7.4 | HDGF PKNOX1 MLX CREB3L1 ARID4B SIN3A FEZF1 ZNF2 YY1 ZNF766 | CSF2RB APOL3 APOL2 NCF4 FOXRED2 ENSG00000228719 TXN2 APOL1 ENSG00000252225 |
| GH22G036348 | 2.1 | FANTOM5 Ensembl ENCODE dbSUPER | 3.6 | -128.9 | -128867 | 40.9 | MLX CREB3L1 DMAP1 YBX1 FEZF1 YY1 SLC30A9 ZNF143 ZNF263 SP3 | TXN2 ENSG00000252225 FOXRED2 MYH9 LOC105377199 APOL3 EIF3D ENSG00000228719 APOL2 NCF4 |
| GH22G036206 | 0.3 | FANTOM5 | 6.5 | +33.5 | 33462 | 0.2 | APOL4 APOL3 APOL2 APOL1 | |
| GH22G036236 | 1.3 | ENCODE dbSUPER | 0.7 | +1.3 | 1344 | 3.7 | HDGF FOXA2 MLX CREB3L1 ARNT WRNIP1 ARID4B SIN3A DMAP1 ZNF2 | APOL4 ENSG00000273176 APOL2 |
| GH22G036249 | 1.5 | FANTOM5 ENCODE dbSUPER | 0.4 | -10.9 | -10907 | 2.7 | PKNOX1 FOXA2 MLX ARID4B ZNF48 ZNF143 SP5 MIER2 PPARG TBX21 | APOL3 MYH9 APOL1 APOL2 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around APOL2 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the APOL2 gene promoter:
Regulatory Element Products
Genomic Location for APOL2 Gene
- Chromosome:
- 22
- Start:
- 36,226,203 bp from pter
- End:
- 36,239,954 bp from pter
- Size:
- 13,752 bases
- Orientation:
- Minus strand
Genomic View for APOL2 Gene
Genes around APOL2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 22q12.3 by Ensembl
- 22q12.3 by Entrez Gene
- 22q12.3 by HGNC
APOL2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for APOL2 Gene
Proteins for APOL2 Gene
-
Protein details for APOL2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9BQE5-APOL2_HUMAN
- Recommended name:
- Apolipoprotein L2
- Protein Accession:
- Q9BQE5
- B0QYK7
- O95915
- Q59GW9
- Q5TH96
- Q969T6
- Q9BT28
- Q9UGT1
- Q9UH10
Protein attributes for APOL2 Gene
- Size:
- 337 amino acids
- Molecular mass:
- 37092 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAD92227.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for APOL2 Gene
Post-translational modifications for APOL2 Gene
Other Protein References for APOL2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for APOL2
-
Abcam antibodies for APOL2
-
Cloud-Clone Corp. Antibodies for APOL2
- Invitrogen Antibodies for APOL2
- antibodies-online Antibodies for APOL2: See all 49
- GeneTex APOL2 antibody for APOL2
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for APOL2
- Origene Custom Protein Services for APOL2
-
Cloud-Clone Corp. Proteins for APOL2
- antibodies-online Proteins for APOL2: See all 3
- Search antibodies-online for peptides
- Search GeneTex for Proteins for APOL2
-
Abcam proteins for APOL2
No data available for DME Specific Peptides for APOL2 Gene
Domains & Families for APOL2 Gene
Gene Families for APOL2 Gene
- HGNC:
Protein Domains for APOL2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for APOL2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9BQE5- Family:
-
- Belongs to the apolipoprotein L family.
Function for APOL2 Gene
Molecular function for APOL2 Gene
- GENATLAS Biochemistry:
- apolipoprotein L,2
- UniProtKB/Swiss-Prot Function:
- May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005102 | receptor binding | NAS | 11374903 |
| GO:0008035 | high-density lipoprotein particle binding | NAS | 11374903 |
| GO:0008289 | lipid binding | IEA,NAS | 11374903 |
Phenotypes for APOL2 Gene
- GenomeRNAi human phenotypes for APOL2:
-
- Increased vaccinia virus (VACV) infection
- Decreased viability in esophageal squamous lineage
- Decreased human papilloma virus 16 (HPV16) pseudovirus infection
- Resistant to vaccinia virus (VACV-A4L) infection
- Increased transferrin (TF) endocytosis
- Negative genetic interaction between KRASG13D/+ and KRAS+/-
- Decreased Salmonella enterica Typhimurium invasion
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for APOL2
-
-
ViGene Biosciences lentiviral particle packaged cDNA for APOL2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for APOL2 gene
- Search ViGene Biosciences for APOL2
CRISPR Products
-
OriGene CRISPR knockouts for APOL2
-
Santa Cruz Biotechnology (SCBT) CRISPR for APOL2
- GenScript: Design CRISPR guide RNA sequences for APOL2
miRNA for APOL2 Gene
- miRTarBase miRNAs that target APOL2
-
- hsa-mir-335-5p (MIRT017248)
- hsa-mir-221-3p (MIRT024143)
- hsa-mir-34a-5p (MIRT025355)
- hsa-mir-1273e (MIRT497229)
- hsa-mir-4302 (MIRT497230)
- hsa-mir-6733-3p (MIRT497231)
- hsa-mir-5094 (MIRT497232)
- hsa-mir-5694 (MIRT497233)
- hsa-mir-383-5p (MIRT497234)
- hsa-mir-3187-3p (MIRT671847)
- hsa-mir-4435 (MIRT671848)
- hsa-mir-588 (MIRT671849)
- hsa-mir-4701-5p (MIRT671850)
- hsa-mir-548s (MIRT671851)
- hsa-mir-7977 (MIRT671852)
- hsa-mir-24-3p (MIRT671853)
- hsa-mir-4284 (MIRT671854)
- hsa-mir-4755-3p (MIRT671855)
miRNA Products
- Search ViGene Biosciences for APOL2
Inhibitory RNA Products
- Origene shRNA, RNAi, and siRNA products in human, mouse, rat for APOL2
- Browse OriGene Inhibitory RNA Products For APOL2
-
ViGene Biosciences ready-to-package AAV shRNAs for APOL2 gene
Clone Products
- Sino Biological Human cDNA Clone for APOL2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for APOL2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for APOL2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for APOL2
-
ViGene Biosciences adenoviral particle packaged cDNA for APOL2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for APOL2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for APOL2 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for APOL2 Gene
Localization for APOL2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for APOL2 Gene
- Cytoplasm.
| Compartment | Confidence |
|---|---|
| endoplasmic reticulum | 5 |
| plasma membrane | 3 |
| cytosol | 3 |
| extracellular | 2 |
| nucleus | 2 |
| peroxisome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005789 | endoplasmic reticulum membrane | NAS | 11374903 |
| GO:0016020 | membrane | IDA,IEA | 19946888 |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for APOL2 Gene
Pathways by source for APOL2 Gene
1 GeneGo (Thomson Reuters) pathway for APOL2 Gene
Interacting Proteins for APOL2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006629 | lipid metabolic process | NAS | 11374903 |
| GO:0006810 | transport | IEA | -- |
| GO:0006869 | lipid transport | IEA,NAS | 11374903 |
| GO:0006953 | acute-phase response | NAS | 11374903 |
| GO:0007275 | multicellular organism development | NAS | 11374903 |
No data available for SIGNOR curated interactions for APOL2 Gene
Transcripts for APOL2 Gene
mRNA/cDNA for APOL2 Gene
- (8) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (164) Selected AceView cDNA sequences:
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for APOL2
-
Santa Cruz Biotechnology (SCBT) CRISPR for APOL2
- GenScript: Design CRISPR guide RNA sequences for APOL2
miRNA Products
- Search ViGene Biosciences for APOL2
Inhibitory RNA Products
- Origene shRNA, RNAi, and siRNA products in human, mouse, rat for APOL2
- Browse OriGene Inhibitory RNA Products For APOL2
-
ViGene Biosciences ready-to-package AAV shRNAs for APOL2 gene
Clone Products
- Sino Biological Human cDNA Clone for APOL2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for APOL2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for APOL2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | · | 4d | · | 4e | · | 4f | · | 4g | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10a | · | 10b | · | 10c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP6: | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - |
Expression for APOL2 Gene
This gene is overexpressed in Nasal epithelium (26.1) and Bone (19.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for APOL2 Gene
NURSA nuclear receptor signaling pathways regulating expression of APOL2 Gene:
APOL2SOURCE GeneReport for Unigene cluster for APOL2 Gene:
Hs.474740mRNA Expression by UniProt/SwissProt for APOL2 Gene:
Q9BQE5-APOL2_HUMAN
Tissue specificity:
Widely expressed; the highest levels are found in lung, thymus, pancreas, placenta, adult brain and prostate; also detected in spleen, liver, kidney, colon, small intestine, uterus, spinal cord, adrenal gland, salivary gland, trachea, mammary gland, skeletal muscle, testis and fetal brain and liver.
Evidence on tissue expression from TISSUES for APOL2 Gene
- Nervous system(4.7)
- Liver(4.4)
- Heart(4.3)
- Pancreas(4.2)
Primer Products
-
OriGene qPCR primer pairs and template standards for APOL2
-
OriGene qPCR primer pairs for APOL2
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for APOL2 Gene
Orthologs for APOL2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | APOL2 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | APOL3 34 35 |
|
||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| mouse (Mus musculus) |
Mammalia | Apol8 34 16 |
|
||
| Apol9b 35 |
|
ManyToMany | |||
| Apol9a 35 |
|
ManyToMany | |||
| Apol10b 35 |
|
ManyToMany | |||
| Apol11a 35 |
|
ManyToMany | |||
| Apol10a 35 |
|
ManyToMany | |||
| Apol11b 35 |
|
ManyToMany | |||
| rat (Rattus norvegicus) |
Mammalia | LOC100911804 34 |
|
||
| dog (Canis familiaris) |
Mammalia | -- 35 |
|
ManyToMany | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
OneToMany | |
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
ManyToMany | |
| -- 35 |
|
ManyToMany | |||
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
ManyToMany | |
| -- 35 |
|
ManyToMany | |||
| zebrafish (Danio rerio) |
Actinopterygii | APOL4 35 |
|
OneToMany |
- Species where no ortholog for APOL2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for APOL2 Gene
(5) SIMAP similar genes for APOL2 Gene using alignment to 4 proteins:
Pseudogenes.org Pseudogenes for APOL2 Gene
Variants for APOL2 Gene
| SNP ID | Clin | Chr 22 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000093192 | -- | 36,232,581(+) | AGGGG(A/G)GGTAA | intron-variant | |
| rs1000145457 | -- | 36,230,496(+) | ACCCT(A/G)GTCCC | intron-variant | |
| rs1000271114 | -- | 36,238,514(+) | CATCT(A/G)CCCTT | intron-variant | |
| rs1000609678 | -- | 36,227,887(+) | GCTCG(C/T)GCCCG | reference, synonymous-codon | |
| rs1000816631 | -- | 36,232,921(+) | GACAG(C/G)GTAGG | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv4564n100 | CNV | gain | 25217958 |
| esv1003985 | CNV | deletion | 20482838 |
| esv2760715 | CNV | gain | 21179565 |
| esv3568384 | CNV | loss | 25503493 |
| esv3647680 | CNV | loss | 21293372 |
| esv3647682 | CNV | gain | 21293372 |
| esv3647683 | CNV | loss | 21293372 |
| esv7844 | OTHER | inversion | 19470904 |
| nsv1129335 | OTHER | inversion | 24896259 |
| nsv522931 | CNV | gain | 19592680 |
| nsv834185 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
80% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
9.42;
88.58% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for APOL2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- APOL2
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for APOL2 Gene
Disorders for APOL2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| schizophrenia |
|
|
| phencyclidine abuse |
|
|
Search APOL2 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for APOL2
No data available for UniProtKB/Swiss-Prot and Genatlas for APOL2 Gene
Publications for APOL2 Gene
- The human apolipoprotein L gene cluster: identification, classification, and sites of distribution. (PMID: 11374903) Page N.M. … Lowry P.J. (Genomics 2001) 2 3 4 64
- Apolipoprotein L gene family: tissue-specific expression, splicing, promoter regions; discovery of a new gene. (PMID: 11290834) Duchateau P.N. … Kane J.P. (J. Lipid Res. 2001) 3 4 22 64
- The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I. … Wright H. (Nature 1999) 2 3 4 64
- Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? (PMID: 20602615) RuaA+o G. … Wu A.H. (Pharmacogenomics 2010) 3 46 64
- Association of SNPs and haplotypes in APOL1, 2 and 4 with schizophrenia. (PMID: 18632255) Takahashi S. … Tsuang M.T. (Schizophr. Res. 2008) 3 46 64
Products for APOL2 Gene
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- GenScript: Design CRISPR guide RNA sequences for APOL2
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- Cloud-Clone Corp. Antibodies for APOL2
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- Cloud-Clone Corp Assay Kits for APOL2
- antibodies-online Antibodies for APOL2: See all 49
- antibodies-online Kits for APOL2: See all 16
- antibodies-online Proteins for APOL2: See all 3
- Search antibodies-online for peptides
- GeneTex APOL2 antibody for APOL2
- Search GeneTex for Proteins for APOL2
- ViGene Biosciences adenoviral particle packaged cDNA for APOL2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for APOL2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for APOL2 gene
- Search ViGene Biosciences for APOL2
- Horizon Cell Lines for APOL2
- Cyagen custom Knockout/knockin (KOKI) mouse models for APOL2
- VectorBuilder custom plasmid, inducible vectors for APOL2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for APOL2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for APOL2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer