APOL1 Gene
protein-coding GIFtS: 61
GCID: GC22P036649
|
|
apolipoprotein L, 1
(Previous symbol: APOL)
| |
Aliases
for APOL1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Apolipoprotein L, 11 2 | | Apo-L3 | | APOL1 2 3 | | ApoL3 | | FSGS42 5 | | ApoL-I3 | | APO-L2 | | Apolipoprotein L3 | | APOL-I2 | | Apolipoprotein L-I3 | | Apolipoprotein L12 | | |
Export aliases for APOL1 gene to outside databasesPrevious GC identifers: GC22P033292 GC22P034920 GC22P034973 GC22P019617 |
Summaries
for APOL1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for APOL1:
This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is arelatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of mostcholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family membermay play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport fromperipheral cells to the liver. Several different transcript variants encoding different isoforms have been found forthis gene. (provided by RefSeq, Nov 2008)
UniProtKB/Swiss-Prot: APOL1_HUMAN, O14791Function: May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesteroltransport from peripheral cells to the liver
Gene Wiki entry for APOL1
|
Genomic Views
for APOL1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000022.10 NC_018933.1 NT_011520.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the APOL1 gene promoter:
Bach1 GR Brachyury RREB-1 GR-beta GR-alpha Roaz
Other transcription factors
Search SABiosciences Chromatin IP Primers for APOL1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat APOL1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q13.1 Ensembl cytogenetic band: 22q12.3 HGNC cytogenetic band: 22q13.1APOL1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22P036649: view genomic region
(about GC identifiers)
Start:
|
36,649,056 bp from pter |
End:
|
36,663,577 bp from pter |
Size:
|
14,522 bases |
Orientation:
|
plus strand |
|
Proteins
for APOL1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: APOL1_HUMAN, O14791 (See
protein sequence)Recommended Name: Apolipoprotein L1 precursor Size: 398 amino acids; 43974 Da
Subunit: In plasma, interacts with APOA1 and mainly associated with large high density lipoprotein particles
Subcellular location: Secreted
Sequence caution: Sequence=AAB81218.2; Type=Erroneous initiation;
Secondary accessions: A5PLQ4 B4DU12 E9PF24 O60804 Q5R3P7 Q5R3P8 Q96AB8 Q96PM4 Q9BQ03Alternative splicing: 3 isoforms: O14791-1 O14791-2 O14791-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for APOL1: NX_O14791
Post-translational modifications:
Phosphorylation sites are present in the extracellular medium1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O14791
APOL1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001130012.1 NP_001130013.1 NP_003652.2 NP_663318.1
ENSEMBL proteins: ENSP00000380448 ENSP00000317674 ENSP00000391206 ENSP00000404525 ENSP00000397141 ENSP00000391302 ENSP00000387372 ENSP00000392514 ENSP00000392857 ENSP00000411507 ENSP00000388477 ENSP00000380449 ENSP00000397625 ENSP00000216178 Reactome Protein details: O14791
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
APOL1 for ontologies About GeneDecksing
APOL1 Antibody Products:
Assay Products for APOL1: |
Protein
Domains /
Families
for APOL1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
APOL1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry O14791ProtoNet protein and cluster: O14791 1 Blocks protein family: IPB008405 Apolipoprotein L
UniProtKB/Swiss-Prot: APOL1_HUMAN, O14791Similarity: Belongs to the apolipoprotein L family |
Function
for APOL1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: APOL1_HUMAN, O14791Function: May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesteroltransport from peripheral cells to the liver
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for APOL1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for APOL1 (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): APOL1 (NM_003661) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for APOL1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat APOL1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for APOL1 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
APOL1 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for APOL1:
|
Pathways & Interactions
for APOL1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cleavage of Alpha-1-Microglobulin | | | 2 | Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF) | | | 3 | African trypanosomiasis | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  GeneGo (Thomson Reuters) Pathway for APOL1
2 
Reactome Pathways for APOL1
1 
Kegg Pathway (Kegg details for APOL1):
APOL1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for APOL1
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
3 Interacting proteins for APOL1 (O147913 ENSP000003176744) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table
APOL1 for ontologies About GeneDecksing
|
Drugs & Compounds
for APOL1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
APOL1 for compounds About GeneDecksing
 Browse Tocris compounds for APOL1
2 Novoseek chemical compound relationships for APOL1 gene About this table
Search CenterWatch for drugs/clinical trials and news about APOL1
|
Transcripts
for APOL1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for APOL1 gene (5 alternative transcripts): NM_001136540.1 NM_001136541.1 NM_003661.3 NM_145343.2 NM_145344.1 Unigene Cluster for APOL1: Apolipoprotein L, 1 Hs.114309 [show with all ESTs]Unigene Representative Sequence: NM_14534315 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000397278 ENST00000319136(uc003ape.3) ENST00000422471 ENST00000475519
ENST00000438034 ENST00000439680 ENST00000427990 ENST00000416338 ENST00000433768
ENST00000431184 ENST00000422706(uc011amn.1 uc021wom.1 uc003apf.3 uc011amp.2 uc010gwx.3)
ENST00000426053(uc011amo.2 uc011amq.2) ENST00000397279 ENST00000440669
ENST00000347595
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for APOL1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for APOL1 (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): APOL1 (NM_003661) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for APOL1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat APOL1 |
Additional cDNA sequence: AF019225.2 AF323540.1 AK296099.1 AK298053.1 AK300454.1 AK303919.1 AK309143.1 AK313752.1 BC112943.1 BC113867.1 BC114475.1 BC127186.1 BC141823.1 BC142720.1 BC143038.1 BC143039.1 14 DOTS entries: DT.97780153 DT.100798675 DT.314461 DT.100798676 DT.100766153 DT.435420 DT.91746769 DT.120655220 DT.100798674 DT.95275477 DT.75127316 DT.91746766 DT.95152345 DT.120655235 24/328 AceView cDNA sequences (see all 328): BG231883 BU584498 AW609789 AW582486 AW582473 BE155758 H55288 AW817142 BE155763 AW817278 AA457728 NM_145344 BE155757 AI123651 AW817138 AW817146 CR626091 H55279 AW817277 BM691318 BU584347 C01172 BF446182 BG164112
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for APOL1 (see all 7) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | · | 6d | ^ | 7a | · | 7b | · | 7c | · | 7d |
|---|
|
| SP1: | | | | | | | | | | | - | | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | - | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for APOL1
|
Expression
for APOL1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| APOL1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAAGCAGTTT
About this image
See APOL1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for APOL1
SOURCE GeneReport for Unigene cluster: Hs.114309
UniProtKB/Swiss-Prot: APOL1_HUMAN, O14791Tissue specificity: Plasma. Found on APOA-I-containing high density lipoprotein (HDL3). Expressed in pancreas, lung,prostate, liver, placenta and spleen
SABiosciences Expression via Pathway-Focused PCR Array including APOL1: | Lipoprotein Signaling & Cholesterol Metabolism in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for APOL1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat APOL1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat APOL1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat APOL1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for APOL1 |
Orthologs
for APOL1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for APOL1 gene from 1/4 species (see all 4) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
---- |
-- |
42(a)35(a) |
many ↔ manymany ↔ many |
5(21779188-21779424) 5(21749807-21750637) |
ENSEMBL Gene Tree for APOL1 (if available)
TreeFam Gene Tree for APOL1 (if available) |
Paralogs
for APOL1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for APOL1 gene
- APOL42 APOL62 APOL22 APOL52 APOL32 APOLD12
5 SIMAP similar genes for APOL1 using alignment to 12 protein entries: APOL1_HUMAN (see all proteins):APOL2 APOL3 APOL4 APOL6 ApoL6
APOL1 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for APOL1
PGOHUM00000246322 PGOHUM00000246325
|
Genomic Variants
for APOL1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 22 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for APOL1 (36649056 - 36663577 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for APOL1
1 Inversion: 59779
Human Gene Mutation Database (HGMD): APOL1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing APOL1 |
|
Disorders
/ Diseases
for APOL1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
APOL1 for disorders About GeneDecksing
OMIM gene information: 603743
OMIM disorders: 612551
UniProtKB/Swiss-Prot: APOL1_HUMAN, O14791
Defects in APOL1 are the cause of focal segmental glomerulosclerosis type 4 (FSGS4) [MIM:612551]. It is arenal pathology defined by the presence of segmental sclerosis in glomeruli and resulting in proteinuria, reducedglomerular filtration rate and edema. Renal insufficiency often progresses to end-stage renal disease, a highly morbidstate requiring either dialysis therapy or kidney transplantation
20  diseases for APOL1: About MalaCardsend-stage renal disease, nondiabetic, susceptibility to glomerulosclerosis, focal segmental, 4 avascular necrosis of femoral head cholesterol
phencyclidine abuse glomerulosclerosis sleeping sickness coronary heart disease
trypanosomiasis hepatitis c nephropathy kidney disease
hyperglycemia alzheimer's disease osteoarthritis schizophrenia
hepatitis fibrosis prostatitis liver fibrosis
2 diseases from the University of Copenhagen DISEASES database for APOL1:Sleeping sickness Kidney disease 2 Novoseek disease relationships for APOL1 gene About this table
Genetic Association Database (GAD): APOL1
Human Genome Epidemiology (HuGE) Navigator: APOL1 (13 documents)
Export disorders for APOL1 gene to outside databases
|
Publications
for APOL1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for APOL1 gene, integrated from 9 sources (see all 90):
(articles sorted by number of sources associating them with APOL1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Apolipoprotein L, a new human high density lipoprotein apolipoprotein expressed by the pancreas. Identification, cloning, characterization, and plasma distribution of apolipoprotein L. (PubMed id 9325276)1, 2, 3, 9 Duchateau P.N.... Kane J.P. (1997)
- The human apolipoprotein L gene cluster: identification, classification, and sites of distribution. (PubMed id 11374903)1, 2, 3, 9 Page N.M....Lowry P.J. (2001)
- Apolipoprotein L gene family: tissue-specific expression, splicing, promoter regions; discovery of a new gene. (PubMed id 11290834)1, 2, 9 Duchateau P.N.... Kane J.P. (2001)
- Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes. (PubMed id 16020735)1, 3, 9 Perez-Morga D....Pays E. (2005)
- Investigation of the apolipoprotein-L (APOL) gene family and schizophrenia using a novel DNA pooling strategy for public database SNPs. (PubMed id 15949655)1, 4, 9 McGhee K.A....Corvin A. (2005)
- Association of trypanolytic ApoL1 variants with kidne y disease in African Americans. (PubMed id 20647424)1, 2 Genovese G....Pollak M.R. (2010)
- Missense mutations in the APOL1 gene are highly assoc iated with end stage kidney disease risk previously attributed to the MYH9 gene . (PubMed id 20635188)1, 2 Tzur S....Skorecki K. (2010)
- Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)1, 2 Liu T.... Smith R.D. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The apolipoprotein L gene cluster has emerged recently in evolution and is expressed in human vascular tissue. (PubMed id 11944986)1, 2 Monajemi H.... Horrevoets A.J.G. (2002)
|
External Searches for APOL1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing APOL1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing APOL1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing APOL1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for APOL1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for APOL1 gene:
Search GeneIP for patents involving APOL1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for APOL1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for APOL1 | | OriGene shRNA RFP for APOL1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for APOL1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for APOL1 | | | OriGene Protein Over-expression Lysate for APOL1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for APOL1 | | OriGene 3'-UTR Clone for APOL1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for APOL1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for APOL1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for APOL1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for APOL1 | | OriGene Custom Protein Services for APOL1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat APOL1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing APOL1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat APOL1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat APOL1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat APOL1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat APOL1 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for APOL1 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | APOL1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for APOL1 |
|  |  |  | | | | ThermoFisher Antibodies for APOL1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat APOL1 |
|
|
|
|
