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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

APOF Gene

protein-coding   GIFtS: 52
GCID: GC12M056754

Apolipoprotein F

Alzheimer's & Parkinson's Diseases Congress
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Apolipoprotein F1 2
Lipid Transfer Inhibitor Protein2 3
Apo-F2 3
LTIP2 3

External Ids:    HGNC: 6151   Entrez Gene: 3192   Ensembl: ENSG000001753367   OMIM: 1077605   UniProtKB: Q137903   

Export aliases for APOF gene to outside databases

Previous GC identifers: GC12P056570 GC12P056542 GC12M056471 GC12M055040 GC12M055010 GC12M053793


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for APOF Gene:
The product of this gene is one of the minor apolipoproteins found in plasma. This protein forms complexes with
lipoproteins and may be involved in transport and/or esterification of cholesterol. (provided by RefSeq, Jul
2008)

GeneCards Summary for APOF Gene: 
APOF (apolipoprotein F) is a protein-coding gene. Diseases associated with APOF include dacryoadenitis, and ossifying fibroma. GO annotations related to this gene include lipid transporter activity and receptor binding.

UniProtKB/Swiss-Prot: APOF_HUMAN, Q13790
Function: Minor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein (CETP)
activity and appears to be an important regulator of cholesterol transport. Also associates to a lesser degree
with VLDL, Apo-AI and Apo-AII

Gene Wiki entry for APOF Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.2  NT_029419.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the APOF gene promoter:
         USF1   RP58   Sp1   p53   SRF (504 AA)   Pax-2   Pax-2a   Pax-2b   USF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAPOF promoter sequence
   Search SABiosciences Chromatin IP Primers for APOF

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat APOF


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.3   Ensembl cytogenetic band:  12q13.3   HGNC cytogenetic band: 12q13

APOF Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
APOF gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M056754:  view genomic region     (about GC identifiers)

Start:
56,754,353 bp from pter      End:
56,756,607 bp from pter
Size:
2,255 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: APOF_HUMAN, Q13790 (See protein sequence)
Recommended Name: Apolipoprotein F precursor  
Size: 326 amino acids; 35399 Da
Subcellular location: Secreted
Caution: It is uncertain whether Met-1 or Met-12 is the initiator
Secondary accessions: Q8TC13

Explore the universe of human proteins at neXtProt for APOF: NX_Q13790

Explore proteomics data for APOF at MOPED 

Post-translational modifications:

  • UniProtKB: O-glycosylated with core 1 or possibly core 8 glycans
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q13790

  • APOF Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    APOF Protein Expression
    REFSEQ proteins: NP_001629.1  
    ENSEMBL proteins: 
     ENSP00000381250   ENSP00000440997  

    Human Recombinant Protein Products for APOF: 
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    OriGene Protein Over-expression Lysate for APOF
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for APOF
    GenScript Custom Purified and Recombinant Proteins Services for APOF
    Novus Biologicals APOF Protein
    Novus Biologicals APOF Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for APOF 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region NAS14718574
    GO:0034362low-density lipoprotein particle IEA--
    GO:0034364high-density lipoprotein particle IEA--

    APOF for ontologies           About GeneDecksing



    APOF Antibody Products: 
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    Abcam antibodies for APOF
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    ThermoFisher Antibodies for APOF
    LSBio Antibodies in human, mouse, rat for APOF 

    Assay Products for APOF: 
    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for APOF
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for APOF 
    Cloud-Clone Corp. CLIAs for APOF


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    APOLIPO: Apolipoproteins

    1 InterPro protein domain:
     IPR026114 APOF

    Graphical View of Domain Structure for InterPro Entry Q13790

    ProtoNet protein and cluster: Q13790


    APOF for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: APOF_HUMAN, Q13790
    Function: Minor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein (CETP)
    activity and appears to be an important regulator of cholesterol transport. Also associates to a lesser degree
    with VLDL, Apo-AI and Apo-AII

         Genatlas biochemistry entry for APOF:
    apoliprotein F,high density,29kDa,only expressed in liver

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005102receptor binding TAS8093033
    GO:0005319lipid transporter activity TAS6816269
    GO:0015485cholesterol binding TAS6816269
         
    APOF for ontologies           About GeneDecksing


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Apof):
     cellular  homeostasis/metabolism  liver/biliary system 

    APOF for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Apoftm1(KOMP)Vlcg for APOF

       inGenious Targeting Laboratory - Custom generated mouse model solutions for APOF 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for APOF

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for APOF 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for APOF 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat APOF
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate APOF:
    hsa-miR-409-5p hsa-miR-570
    SwitchGear 3'UTR luciferase reporter plasmidAPOF 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for APOF
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    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for APOF
    Sirion Biotech Customized adenovirus for overexpression of APOF

    Clone
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    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for APOF (see all 8)
    OriGene ORF clones in mouse, rat for APOF
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: APOF (NM_001638)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for APOF
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat APOF
    Sirion Biotech Customized lentivirus for stable overexpression of APOF 
                         Customized lentivirus expression plasmids for stable overexpression of APOF 

    Cell Line
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    Search LifeMap BioReagents cell lines for APOF
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for APOF


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for APOF

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for APOF (Q137903 ENSP000003812504) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APOA1P026473, ENSP000002368504I2D: score=2 STRING: ENSP00000236850
    APOA2P026523, ENSP000003569694I2D: score=2 STRING: ENSP00000356969
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006629lipid metabolic process TAS8093033
    GO:0006641triglyceride metabolic process IEA--
    GO:0006869lipid transport TAS6816269
    GO:0008203cholesterol metabolic process IEA--
    GO:0033344cholesterol efflux IEA--

    APOF for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    APOF for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for APOF

    4 Novoseek inferred chemical compound relationships for APOF gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    sodium oleate 79.3 2 9409291 (1), 10903478 (1)
    oleic acid 62 11 10903478 (3), 9409291 (2), 12951364 (2), 9880564 (1) (see all 5)
    lipid 51.1 46 7868987 (5), 10903478 (3), 12907677 (3), 8241106 (3) (see all 15)
    cholesterol 25.8 15 19008531 (5), 19008550 (2), 9327768 (1), 11597939 (1) (see all 5)

    Search CenterWatch for drugs/clinical trials and news about APOF

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for APOF gene: 
    NM_001638.2  

    Unigene Cluster for APOF:

    Apolipoprotein F
    Hs.534302  [show with all ESTs]
    Unigene Representative Sequence: BC026257
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000398189(uc001sle.1) ENST00000541105

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat APOF
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate APOF:
    hsa-miR-409-5p hsa-miR-570
    SwitchGear 3'UTR luciferase reporter plasmidAPOF 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for APOF
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat APOF
    Clone
    Products:
         
    OriGene clones in human, mouse for APOF (see all 8)
    OriGene ORF clones in mouse, rat for APOF
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: APOF (NM_001638)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for APOF
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat APOF
    Sirion Biotech Customized lentivirus for stable overexpression of APOF 
                         Customized lentivirus expression plasmids for stable overexpression of APOF 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for APOF
    OriGene qSTAR qPCR primer pairs in human, mouse for APOF
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat APOF
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat APOF
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat APOF

    Additional mRNA sequence: 

    AK314892.1 BC026257.1 CR936663.1 

    1 DOTS entry:

    DT.100741662 

    10 AceView cDNA sequences:

    CB111959 CB157009 NM_001638 CB162822 T58816 BG566119 BC026257 AI075820 
    L27050 T58748 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    APOF expression in normal human tissues (normalized intensities)      APOF embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTCAAAAAA
    APOF Expression
    About this image


    APOF expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Liver (Hepatobiliary System)
             Liver Lobule
     
     Bone (Muscoskeletal System)
             Zeugopod Growth Plate
     
     Blood (Cardiovascular System)
             Conventional Dendritic Cells II Spleen
     
     Spleen (Hematopoietic System)
             Conventional Dendritic Cells II Spleen
     
     Prostate (Endocrine System)

    See APOF Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for APOF

    SOURCE GeneReport for Unigene cluster: Hs.534302

    UniProtKB/Swiss-Prot: APOF_HUMAN, Q13790
    Tissue specificity: Expressed by the liver and secreted in plasma

        SABiosciences Expression via Pathway-Focused PCR Arrays including APOF: 
              Lipoprotein Signaling & Cholesterol Metabolism in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for APOF

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for APOF gene from 3/7 species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Apof1 , 5 apolipoprotein F1, 5 74.01(n)1
    62.94(a)1
      10 (76.50 cM)5
    1031611  NM_133997.21  NP_598758.11 
     1282679975 
    lizard
    (Anolis carolinensis)
    Reptilia APOF6
    Uncharacterized protein
    33(a)
    1 ↔ 1
    2(93293335-93297173)
    zebrafish
    (Danio rerio)
    Actinopterygii apof6
    apolipoprotein F
    19(a)
    1 ↔ 1
    6(39094320-39095498)


    ENSEMBL Gene Tree for APOF (if available)
    TreeFam Gene Tree for APOF (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for APOF gene

    APOF for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for APOF
    PGOHUM00000239476 PGOHUM00000239478


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/59 SNPs in APOF are shown (see all 59)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0555204
    ----see VAR_0555202 A G mis40--------
    rs1458499801,2
    C--56756045(+) AGTTAA/GGGGGA 1 -- int10--------
    rs3727637031,2
    C--56756106(+) AGGGTA/CTGCTC 1 -- int10--------
    rs1387612111,2
    --56756137(+) CAGTGA/CTGGGA 1 -- int10--------
    rs349345551,2
    C,F--56756176(+) GGGCTC/TGAGGG 1 -- int14Minor allele frequency- T:0.38NA 8
    rs1913353451,2
    C--56756265(+) TAGAGA/GCGTGG 1 -- int10--------
    rs1434718131,2
    --56756329(+) ACCTCC/TGCCTC 1 -- int10--------
    rs1124685401,2
    C,F--56756367(+) CCACCG/ACGCCT 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs1850972281,2
    --56756368(+) CACCGC/TGCCTG 1 -- int10--------
    rs787394611,2
    C,F--56756396(-) TTACCT/GAAAAA 1 -- int11Minor allele frequency- G:0.01MN 3380

    HapMap Linkage Disequilibrium report for APOF (56754353 - 56756607 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for APOF:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv482992CNV Complex15286789

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing APOF
    DNA2.0 Custom Variant and Variant Library Synthesis for APOF

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 107760    OMIM disorders: --

    8 diseases for APOF:    About MalaCards
    dacryoadenitis    ossifying fibroma    peritonitis    coronary heart disease
    hepatitis c    atherosclerosis    alzheimer's disease    hepatitis

    1 disease from the University of Copenhagen DISEASES database for APOF:
    Dacryoadenitis

    APOF for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): APOF
    Human Genome Epidemiology (HuGE) Navigator: APOF (6 documents)

    Export disorders for APOF gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for APOF gene, integrated from 9 sources (see all 35):
    (articles sorted by number of sources associating them with APOF)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Purification and molecular cloning of human apolipoprotein F. (PubMed id 8093033)1, 2, 3, 9 Day J.R....Wolfbauer G. (1994)
    2. Molecular cloning and expression of lipid transfer inhibitor protein reveals its identity with apolipoprotein F. (PubMed id 9880564)1, 2, 9 Wang X.... Morton R.E. (1999)
    3. Common genetic variation in multiple metabolic pathwa ys influences susceptibility to low HDL-cholesterol and coronary heart disease. (PubMed id 20855565)1, 4 Peloso G.M....Brousseau M.E. (2010)
    4. Physiogenomic analysis of statin-treated patients: do main-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? (PubMed id 20602615)1, 4 RuaA+o G....Wu A.H. (2010)
    5. Large-scale candidate gene analysis of spontaneous cl earance of hepatitis C virus. (PubMed id 20331378)1, 4 Mosbruger T.L....Thio C.L. (2010)
    6. Joint effects of common genetic variants from multipl e genes and pathways on the risk of premature coronary artery disease. (PubMed id 20691829)1, 4 Anderson J.L....Carlquist J.F. (2010)
    7. Candidate genetic analysis of plasma high-density lip oprotein-cholesterol and severity of coronary atherosclerosis. (PubMed id 19878569)1, 4 Chen S.N....Marian A.J. (2009)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    9. Exclusion of CYP46 and APOM as candidate genes for Alzheimer's disease in a French population. (PubMed id 15172102)1, 4 Kabbara A....Lambert J.C. (2004)
    10. Isolation and partial characterization of a new acidic apolipoprotein (apolipoprotein F) from high density lipoproteins of human plasma. (PubMed id 204339)1, 2 Olofsson S.-O.... Alaupovic P. (1978)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 319 HGNC: 615 AceView: APOF Ensembl:ENSG00000175336 euGenes: HUgn319
    ECgene: APOF H-InvDB: APOF

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for APOF Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for APOF gene:
    Search GeneIP for patents involving APOF

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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