Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

APOBEC4 Gene

protein-coding   GIFtS: 42
GCID: GC01M183615

Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like...

(Previous name: chromosome 1 open reading frame 169)
(Previous symbol: C1orf169)
  Search for APOBEC4
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 4
(Putative)1 2
C1orf1691 2 3
Apolipoprotein B MRNA-Editing Enzyme Catalytic Polypeptide-Like 42 3
Chromosome 1 Open Reading Frame 1691
Putative C->U-Editing Enzyme APOBEC-42
EC 3.5.4.-3

External Ids:    HGNC: 321521   Entrez Gene: 4033142   Ensembl: ENSG000001736277   OMIM: 6099085   UniProtKB: Q8WW273   

Export aliases for APOBEC4 gene to outside databases

Previous GC identifers: GC01M180349 GC01M181882 GC01M154851


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for APOBEC4 Gene:
This gene encodes a member of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases, which convert
cytidine to uridine. Other AID/APOBEC family members are involved in mRNA editing, somatic hypermutation and
recombination of immunoglobulin genes, and innate immunity to retroviral infection. (provided by RefSeq, Jul
2008)

GeneCards Summary for APOBEC4 Gene: 
APOBEC4 (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)) is a protein-coding gene. GO annotations related to this gene include hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines and zinc ion binding.

UniProtKB/Swiss-Prot: ABEC4_HUMAN, Q8WW27
Function: Putative C to U editing enzyme whose physiological substrate is not yet known (By similarity)

Gene Wiki entry for APOBEC4 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the APOBEC4 gene promoter:
         USF1   Sox5   MEF-2A   FAC1   SREBP-1a   USF-1   FOXJ2 (long isoform)   ZID   aMEF-2   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAPOBEC4 promoter sequence
   Search SABiosciences Chromatin IP Primers for APOBEC4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat APOBEC4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q25.3   Ensembl cytogenetic band:  1q25.3   HGNC cytogenetic band: 1q25.3

APOBEC4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
APOBEC4 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M183615:  view genomic region     (about GC identifiers)

Start:
183,615,410 bp from pter      End:
183,622,451 bp from pter
Size:
7,042 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ABEC4_HUMAN, Q8WW27 (See protein sequence)
Recommended Name: Putative C->U-editing enzyme APOBEC-4  
Size: 367 amino acids; 41581 Da
Cofactor: Zinc (By similarity)
Secondary accessions: Q8N7F6

Explore the universe of human proteins at neXtProt for APOBEC4: NX_Q8WW27

Explore proteomics data for APOBEC4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8WW27

  • APOBEC4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    APOBEC4 Protein Expression
    REFSEQ proteins: NP_982279.1  
    ENSEMBL proteins: 
     ENSP00000310622  

    Human Recombinant Protein Products for APOBEC4: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for APOBEC4
    GenScript Custom Purified and Recombinant Proteins Services for APOBEC4
    Novus Biologicals APOBEC4 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for APOBEC4 


    APOBEC4 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for APOBEC4
    GenScript Custom Superior Antibodies Services for APOBEC4
    Novus Biologicals APOBEC4 Antibodies
    Abcam antibodies for APOBEC4
    Cloud-Clone Corp. Antibodies for APOBEC4 
    Search ThermoFisher Antibodies for APOBEC4
    LSBio Antibodies in human, mouse, rat for APOBEC4 

    Assay Products for APOBEC4: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for APOBEC4
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for APOBEC4
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for APOBEC4 
    Cloud-Clone Corp. CLIAs for APOBEC4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    APOBEC: Apolipoprotein B mRNA editing enzymes

    1 InterPro protein domain:
     IPR013158 APOBEC_N

    Graphical View of Domain Structure for InterPro Entry Q8WW27

    ProtoNet protein and cluster: Q8WW27

    1 Blocks protein domain: IPB002125 Cytidine/deoxycytidylate deaminase

    UniProtKB/Swiss-Prot: ABEC4_HUMAN, Q8WW27
    Similarity: Belongs to the cytidine and deoxycytidylate deaminase family


    APOBEC4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ABEC4_HUMAN, Q8WW27
    Function: Putative C to U editing enzyme whose physiological substrate is not yet known (By similarity)

         Enzyme Number (IUBMB): EC 3.5.4.-1

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008270zinc ion binding IEA--
    GO:0016814hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines IEA--
         
    APOBEC4 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for APOBEC4 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for APOBEC4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for APOBEC4 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for APOBEC4 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat APOBEC4
    8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate APOBEC4 (see all 10):
    hsa-miR-2052 hsa-miR-374b hsa-miR-4306 hsa-miR-374a hsa-miR-29b-1* hsa-miR-223 hsa-miR-4261 hsa-miR-185
    SwitchGear 3'UTR luciferase reporter plasmidAPOBEC4 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for APOBEC4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat APOBEC4

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for APOBEC4
    Sirion Biotech Customized adenovirus for overexpression of APOBEC4

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for APOBEC4 (see all 7)
    OriGene ORF clones in mouse, rat for APOBEC4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: APOBEC4 (NM_203454)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for APOBEC4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat APOBEC4
    Sirion Biotech Customized lentivirus for stable overexpression of APOBEC4 
                         Customized lentivirus expression plasmids for stable overexpression of APOBEC4 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for APOBEC4
    Search LifeMap BioReagents cell lines for APOBEC4
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for APOBEC4


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for APOBEC4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    5/14 Interacting proteins for APOBEC4 (ENSP000003106224) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CACYBPENSP000003566524STRING: ENSP00000356652
    COL11A1ENSP000003511634STRING: ENSP00000351163
    CTSKENSP000002716514STRING: ENSP00000271651
    ENSG00000236342ENSP000004125534STRING: ENSP00000412553
    HORMAD1ENSP000003551674STRING: ENSP00000355167
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006397mRNA processing IEA--

    APOBEC4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for APOBEC4 (ABEC4)

    Search CenterWatch for drugs/clinical trials and news about APOBEC4 / ABEC4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for APOBEC4 gene: 
    NM_203454.2  

    Unigene Cluster for APOBEC4:

    Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
    Hs.97335  [show with all ESTs]
    Unigene Representative Sequence: NM_203454
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000308641(uc001gqn.3) ENST00000481562
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat APOBEC4
    8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate APOBEC4 (see all 10):
    hsa-miR-2052 hsa-miR-374b hsa-miR-4306 hsa-miR-374a hsa-miR-29b-1* hsa-miR-223 hsa-miR-4261 hsa-miR-185
    SwitchGear 3'UTR luciferase reporter plasmidAPOBEC4 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for APOBEC4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat APOBEC4
    Clone
    Products:
         
    OriGene clones in human, mouse for APOBEC4 (see all 7)
    OriGene ORF clones in mouse, rat for APOBEC4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: APOBEC4 (NM_203454)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for APOBEC4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat APOBEC4
    Sirion Biotech Customized lentivirus for stable overexpression of APOBEC4 
                         Customized lentivirus expression plasmids for stable overexpression of APOBEC4 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for APOBEC4
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat APOBEC4
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat APOBEC4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat APOBEC4

    Additional mRNA sequence: 

    AK098557.1 BC021711.2 

    1 DOTS entry:

    DT.40224150 

    17 AceView cDNA sequences:

    NM_203454 BX094690 AI961390 AA292880 AA382354 BC021711 BU676426 AK098557 
    AA406043 BI770442 AA496090 BI828948 AA401696 BG722665 CD684537 CD710557 
    BI770969 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    APOBEC4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATAAAAATT
    APOBEC4 Expression
    About this image


    See APOBEC4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for APOBEC4

    SOURCE GeneReport for Unigene cluster: Hs.97335

    UniProtKB/Swiss-Prot: ABEC4_HUMAN, Q8WW27
    Tissue specificity: Predominantly expressed in testis

        SABiosciences Custom PCR Arrays for APOBEC4
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for APOBEC4
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat APOBEC4
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat APOBEC4
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat APOBEC4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for APOBEC4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for APOBEC4 gene from 3/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Apobec41 , 5 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like more1, 5 74.67(n)1
    63.41(a)1
      1 (65.01 cM)5
    712811  NM_001081197.11  NP_001074666.11 
     1527505515 
    chicken
    (Gallus gallus)
    Aves LOC1008589261 putative C->U-editing enzyme APOBEC-4-like 63.61(n)
    60.87(a)
      100858926  XM_003641679.1  XP_003641727.1 
    lizard
    (Anolis carolinensis)
    Reptilia APOBEC46
    Uncharacterized protein
    53(a)
    1 ↔ 1
    GL343203.1(4021684-4022733)


    ENSEMBL Gene Tree for APOBEC4 (if available)
    TreeFam Gene Tree for APOBEC4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    6 SNPs in APOBEC4 are shown    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0266424
    ----see VAR_0266422 K E mis40--------
    VAR_0266394
    ----see VAR_0266392 S F mis40--------
    VAR_0266404
    ----see VAR_0266402 F S mis40--------
    VAR_0266414
    ----see VAR_0266412 P S mis40--------
    VAR_0266434
    ----see VAR_0266432 V M mis40--------
    VAR_0487244
    ----see VAR_0487242 D G mis40--------

    HapMap Linkage Disequilibrium report for APOBEC4 (183615410 - 183622451 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for APOBEC4:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv872582CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing APOBEC4
    DNA2.0 Custom Variant and Variant Library Synthesis for APOBEC4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    APOBEC4 for disorders           About MalaCards
    OMIM gene information: 609908    OMIM disorders: --


    APOBEC4 for disorders           About GeneDecksing


    Export disorders for APOBEC4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for APOBEC4 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with APOBEC4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. APOBEC4, a new member of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases predicted by computational analysis. (PubMed id 16082223)1, 2, 3 Rogozin I.B.... Koonin E.V. (2005)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lup us erythematosus in Asians. (PubMed id 23273568)1 Yang W....Lau Y.L. (2013)
    6. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
    7. APOBEC deaminases-mutases with defensive roles for im munity. (PubMed id 19911124)1 Prochnow C....Chen X.S. (2009)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 403314 HGNC: 32152 AceView: MGC26594 Ensembl:ENSG00000173627 euGenes: HUgn403314
    ECgene: APOBEC4 H-InvDB: APOBEC4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for APOBEC4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for APOBEC4 gene:
    Search GeneIP for patents involving APOBEC4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for APOBEC4  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for APOBEC4  
     OriGene qSTAR qPCR primer pairs in human, mouse for APOBEC4   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for APOBEC4   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for APOBEC4   OriGene Custom Protein Services for APOBEC4  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat APOBEC4
     QIAGEN SeqTarget long-range PCR primers for resequencing APOBEC4
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat APOBEC4
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat APOBEC4
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat APOBEC4
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat APOBEC4
     GenScript Custom Purified and Recombinant Proteins Services for APOBEC4 GenScript cDNA clones with any tag delivered in your preferred vector for APOBEC4
     GenScript Custom Assay Services for APOBEC4 GenScript Custom Superior Antibodies Services for APOBEC4
     GenScript Custom overexpressing Cell Line Services for APOBEC4 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in APOBEC4 promoter
     Search Chromatin IP Primers for APOBEC4
     RT2 qPCR Primer Assay in human, mouse, rat APOBEC4
     Search GNC Networks for APOBEC4
     SABiosciences Custom PCR Arrays for APOBEC4
     Search Tocris compounds for APOBEC4 (ABEC4)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     APOBEC4 antibodies
     APOBEC4 proteins
     Antibodies for APOBEC4
     See all of Abcam's Antibodies, Kits and Proteins for APOBEC4
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for APOBEC4
     Antibodies for APOBEC4
     ELISAs for APOBEC4
     CLIAs for APOBEC4
     Search LifeMap BioReagents cell lines for APOBEC4
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for APOBEC4
     SwitchGear 3'UTR luciferase reporter plasmids for APOBEC4
     SwitchGear Promoter luciferase reporter plasmids for APOBEC4
     Search ThermoFisher Antibodies for APOBEC4
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat APOBEC4
     inGenious Targeting Laboratory - Custom generated mouse model solutions for APOBEC4
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for APOBEC4
    Customized:
     lentivirus for stable overexpression of APOBEC4
     lentivirus expression plasmids for stable overexpression of APOBEC4
     adenovirus for overexpression of APOBEC4
     LSBio Antibodies in human, mouse, rat for APOBEC4
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      APOBEC4 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4