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APOBEC3H Gene

protein-coding   GIFtS: 45
GCID: GC22P039493

Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like...

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3H1 2     ARP102 5
Apolipoprotein B MRNA-Editing Enzyme Catalytic Polypeptide-Like 3H2 3     Apolipoprotein B Editing Enzyme Catalytic Polypeptide-Like 3H2
A3H2 3     DNA DC->DU-Editing Enzyme APOBEC-3H2
ARP-102 3     EC 3.5.4.-3
APOBEC-Related Protein 102 3     

External Ids:    HGNC: 241001   Entrez Gene: 1646682   Ensembl: ENSG000001002987   OMIM: 6109765   UniProtKB: Q6NTF73   

Export aliases for APOBEC3H gene to outside databases

Previous GC identifers: GC22P037823 GC22P022460


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for APOBEC3H Gene:
This gene encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins.
The encoded protein is a cytidine deaminase that has antiretroviral activity by generating lethal hypermutations
in viral genomes. Polymorphisms and alternative splicing in this gene influence its antiretroviral activity and
are associated with increased resistence to human immunodeficiency virus type 1 infection in certain populations.
Alternative splicing results in multiple transcript variants.(provided by RefSeq, Oct 2009)

GeneCards Summary for APOBEC3H Gene:
APOBEC3H (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H) is a protein-coding gene. GO annotations related to this gene include cytidine deaminase activity. An important paralog of this gene is APOBEC3G.

UniProtKB/Swiss-Prot: ABC3H_HUMAN, Q6NTF7
Function: DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and
retrotransposon mobility via deaminase-dependent and -independent mechanisms. The A3H-var/haplotype 2 exhibits
antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target
cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to
uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand
viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a
deamination-independent mechanism that works prior to the proviral integration, together exert efficient
antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate
double-stranded DNA or single- or double-stranded RNA. Exhibits antiviral activity also against T-cell leukemia
virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons

Gene Wiki entry for APOBEC3H Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000022.10  NC_018933.2  NT_011520.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the APOBEC3H gene promoter:
         GR   SREBP-1c   XBP-1   MIF-1   SREBP-1b   C/EBPalpha   Max   SREBP-1a   GR-alpha   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAPOBEC3H promoter sequence
   Search Chromatin IP Primers for APOBEC3H

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat APOBEC3H


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.1   Ensembl cytogenetic band:  22q13.1   HGNC cytogenetic band: 22q13.1

APOBEC3H Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
APOBEC3H gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P039493:  view genomic region     (about GC identifiers)

Start:
39,493,229 bp from pter      End:
39,500,072 bp from pter
Size:
6,844 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ABC3H_HUMAN, Q6NTF7 (See protein sequence)
Recommended Name: DNA dC->dU-editing enzyme APOBEC-3H  
Size: 200 amino acids; 23531 Da
Cofactor: Zinc (By similarity)
Subunit: Interacts with AGO1, AGO2 and AGO3
Miscellaneous: APOBEC3H from old world monkeys has retained its antiviral activity, while it is lost in other
primates
Miscellaneous: It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene
duplication, on chromosome 22
Secondary accessions: B0QYP0 B0QYP1 B7TQM5 E9PF38 Q5JYL9 Q6IC87
Alternative splicing: 4 isoforms:  Q6NTF7-1   Q6NTF7-2   Q6NTF7-3   Q6NTF7-4   (Gene prediction based on EST data)

Explore the universe of human proteins at neXtProt for APOBEC3H: NX_Q6NTF7

Explore proteomics data for APOBEC3H at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See APOBEC3H Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001159474.1  NP_001159475.1  NP_001159476.1  NP_861438.2  

    ENSEMBL proteins: 
     ENSP00000216123   ENSP00000385741   ENSP00000411754   ENSP00000393520  

    APOBEC3H Human Recombinant Protein Products:

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    antibodies-online proteins for APOBEC3H (2 products) 

     
    antibodies-online peptides for APOBEC3H

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    antibodies-online kits for APOBEC3H (3 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    APOBEC: Apolipoprotein B mRNA editing enzymes

    4 InterPro protein domains:
     IPR016192 APOBEC/CMP_deaminase_Zn-bd
     IPR002125 CMP_dCMP_Zn-bd
     IPR007904 APOBEC_C
     IPR016193 Cytidine_deaminase-like

    Graphical View of Domain Structure for InterPro Entry Q6NTF7

    ProtoNet protein and cluster: Q6NTF7

    2 Blocks protein domains:
    IPB002125 Cytidine/deoxycytidylate deaminase
    IPB007904 APOBEC-like


    UniProtKB/Swiss-Prot: ABC3H_HUMAN, Q6NTF7
    Similarity: Belongs to the cytidine and deoxycytidylate deaminase family
    Similarity: Contains 1 CMP/dCMP deaminase zinc-binding domain


    Find genes that share domains with APOBEC3H           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ABC3H_HUMAN, Q6NTF7
    Function: DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and
    retrotransposon mobility via deaminase-dependent and -independent mechanisms. The A3H-var/haplotype 2 exhibits
    antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target
    cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to
    uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand
    viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a
    deamination-independent mechanism that works prior to the proviral integration, together exert efficient
    antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate
    double-stranded DNA or single- or double-stranded RNA. Exhibits antiviral activity also against T-cell leukemia
    virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons
    Catalytic activity: Cytidine + H(2)O = uridine + NH(3)
    Enzyme regulation: Antiviral activity is neutralized by the HIV-1 virion infectivity factor (VIF), that prevents
    its incorporation into progeny virions by both inhibiting its translation and/or by inducing its ubiquitination
    and subsequent degradation by the 26S proteasome

         Enzyme Number (IUBMB): EC 3.5.4.-1

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0004126cytidine deaminase activity IDA16571802
    GO:0005515protein binding IPI--
    GO:0008270zinc ion binding IEA--
    GO:0016787hydrolase activity ----
         
    Find genes that share ontologies with APOBEC3H           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for APOBEC3H

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ABC3H_HUMAN, Q6NTF7: Nucleus. Cytoplasm. Cytoplasm, P-body. Note=Haplotype 1 is distributed in both the nucleus
    and cytoplasm, whereas haplotype 2 is predominantly cytoplasmic
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    extracellular2
    mitochondrion2

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000932cytoplasmic mRNA processing body IDA--
    GO:0005634nucleus IDA18779051
    GO:0005737cytoplasm IDA18779051

    Find genes that share ontologies with APOBEC3H           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for APOBEC3H
    Interactions:

        Search GeneGlobe Interaction Network for APOBEC3H

    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0009972cytidine deamination IDA16571802
    GO:0010529negative regulation of transposition IMP18827027
    GO:0045087innate immune response IEA--
    GO:0045869negative regulation of single stranded viral RNA replication via double stranded DNA intermediate IDA18779051
    GO:0048525negative regulation of viral process IMP18827027

    Find genes that share ontologies with APOBEC3H           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for APOBEC3H (ABC3H)

    1 HMDB Compound for APOBEC3H    About this table
    CompoundSynonyms CAS #PubMed Ids
    Cytidine1-(b-D-Ribofuranosyl)-2-oxo-4-amino-1,2-dihydro-1,3-diazine (see all 20)65-46-3--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for APOBEC3H gene (4 alternative transcripts): 
    NM_001166002.1  NM_001166003.1  NM_001166004.1  NM_181773.3  

    Unigene Cluster for APOBEC3H:

    Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
    Hs.440515  [show with all ESTs]
    Unigene Representative Sequence: NM_001166003
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000348946(uc021wpv.1) ENST00000474235 ENST00000401756 ENST00000442487(uc021wpt.1 uc021wpu.1)
    ENST00000421988(uc021wps.1)
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      QuantiFast Probe-based Assays in human, mouse, rat APOBEC3H

    Additional mRNA sequence: 

    BC069023.1 CR456481.3 FJ376611.1 FJ376612.1 FJ376613.1 FJ376614.1 FJ376615.1 FJ376616.1 
    FJ376617.1 

    2 DOTS entries:

    DT.97797484  DT.75167672 

    Selected AceView cDNA sequences (see all 25):

    BC069023 BU584253 BQ052182 AI768819 BU584220 BX403778 NM_181773 BU585251 
    BU585256 BM563403 AW294386 BQ054330 BX283784 BV188196 BX453936 BX449285 
    CR456481 BX449284 BU585257 BU585255 AI492244 BU584484 BU585254 BX430257 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    APOBEC3H expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCAGTTGCCT
    APOBEC3H Expression
    About this image

    APOBEC3H Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    APOBEC3H Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.440515

    UniProtKB/Swiss-Prot: ABC3H_HUMAN, Q6NTF7
    Tissue specificity: Expressed in lymphoid organs. Also detected in non-lymphoid tissues including lung, testis,
    ovary, fetal liver and skin

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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      --

    ENSEMBL Gene Tree for APOBEC3H (if available)
    TreeFam Gene Tree for APOBEC3H (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for APOBEC3H gene
    APOBEC3G2  APOBEC3F2  APOBEC12  APOBEC22  APOBEC3B2  APOBEC3D2  APOBEC3C2  APOBEC3A2  
    AICDA2  
    6 SIMAP similar genes for APOBEC3H using alignment to 9 protein entries:     ABC3H_HUMAN (see all proteins):
    bK150C2.9    AICDA    APOBEC3G    AID    APOBEC3A    APOBEC3F

    Find genes that share paralogs with APOBEC3H           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Polymorphic Variants from UniProtKB/Swiss-Prot
    ABC3H_HUMAN, Q6NTF7: There are at least 4 different haplotypes in the human population. The allele A3H-var/haplotype 2
    encodes a more stable protein which is able to block HIV-1 replication. The displayed allele (haplotype 1) is
    unstable and inefficient to block HIV-1 replication


    Selected SNPs for APOBEC3H (see all 297)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs784416651,2
    C,F--39491233(+) AGGAAA/GGGGTT 4 -- us2k12Minor allele frequency- G:0.14CSA WA 120
    rs1883728511,2
    --39491378(+) CCCCAA/GCATTT 4 -- us2k10--------
    rs60014281,2
    C,F,A,H--39491379(+) CCCAAC/TATTTA 4 -- us2k17Minor allele frequency- T:0.09NS NA EA 604
    rs578522541,2
    C--39491381(+) ACATT-/TAGGAC 4 -- us2k10--------
    rs1865034911,2
    --39491416(+) TTCCCA/CGGAAC 4 -- us2k10--------
    rs734235481,2
    C--39491572(+) GTGACC/TGCCCC 4 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1401044531,2
    C--39491600(+) ATTCAA/GCTTTC 4 -- us2k10--------
    rs1120157031,2
    C,F--39491904(+) CAGGCG/ATGAGC 4 -- us2k11Minor allele frequency- A:0.50WA 2
    rs1454990261,2
    --39491957(+) GTGTTG/TGTTGA 4 -- us2k10--------
    rs1913445191,2
    --39492037(+) GGAGGC/TCCTTT 4 -- us2k10--------

    HapMap Linkage Disequilibrium report for APOBEC3H (39493229 - 39500072 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for APOBEC3H:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv915090CNV Loss21882294
    nsv510807CNV Loss20534489
    nsv834196CNV Loss17160897
    dgv4973n71CNV Loss21882294
    nsv834197CNV Gain17160897

    Human Gene Mutation Database (HGMD): APOBEC3H
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing APOBEC3H
    DNA2.0 Custom Variant and Variant Library Synthesis for APOBEC3H

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610976    OMIM disorders: --


    Find genes that share disorders with APOBEC3H           About GenesLikeMe


    Export disorders for APOBEC3H gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for APOBEC3H gene, integrated from 10 sources (see all 41):
    (articles sorted by number of sources associating them with APOBEC3H)
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    1. Adaptive evolution and antiviral activity of the conserved mammalian cytidine deaminase APOBEC3H. (PubMed id 16571802)1, 2, 3 OhAinle M.... Emerman M. (J. Virol. 2006)
    2. APOBEC3A, APOBEC3B, and APOBEC3H haplotype 2 restrict human T- lymphotropic virus type 1. (PubMed id 22457529)1, 2 Ooms M.... Muenk C. (J. Virol. 2012)
    3. Polymorphism in human APOBEC3H affects a phenotype dominant for subcellular localization and antiviral activity. (PubMed id 21653666)1, 2 Li M.M. and Emerman M. (J. Virol. 2011)
    4. Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1. (PubMed id 21835787)1, 2 Hultquist J.F.... Harris R.S. (J. Virol. 2011)
    5. Sole copy of Z2-type human cytidine deaminase APOBEC3H has inhibitory activity against retrotransposons and HIV-1. (PubMed id 18827027)1, 2 Tan L.... Yu X.F. (FASEB J. 2009)
    6. Polymorphisms and splice variants influence the antiretroviral activity of human APOBEC3H. (PubMed id 18945781)1, 2 Harari A.... Simon V. (J. Virol. 2009)
    7. Human cytidine deaminase APOBEC3H restricts HIV-1 replication. (PubMed id 18299330)1, 2 Dang Y.... Zheng Y.H. (J. Biol. Chem. 2008)
    8. Antiretroelement activity of APOBEC3H was lost twice in recent human evolution. (PubMed id 18779051)1, 2 OhAinle M.... Emerman M. (Cell Host Microbe 2008)
    9. A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (Genome Biol. 2004)
    10. Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business. (PubMed id 12683974)1, 2 Wedekind J.E.... Smith H.C. (Trends Genet. 2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 164668 HGNC: 24100 AceView: ARP10 Ensembl:ENSG00000100298 euGenes: HUgn164668
    ECgene: APOBEC3H H-InvDB: APOBEC3H

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for APOBEC3H Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for APOBEC3H gene:
    Search GeneIP for patents involving APOBEC3H

    GeneCards and IP:
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