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APOBEC3D Gene

protein-coding   GIFtS: 47
GCID: GC22P039418

Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like...

(Previous names: apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like...)
(Previous symbol: APOBEC3E)
Microbiology & Infectious Diseases Congress
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3D1 2     ARP62
APOBEC3E1 2     DNA DC->DU-Editing Enzyme APOBEC-3D2
Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3E
Pseudogene1 2
     Probable DNA DC->DU-Editing Enzyme APOBEC-3D2
A3D2 3     EC 3.5.4.-3
Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3D
(Putative)1
     EC 3.5.48
APOBEC3DE2     

External Ids:    HGNC: 173541   Entrez Gene: 1405642   Ensembl: ENSG000002438117   OMIM: 6099005   UniProtKB: Q96AK33   

Export aliases for APOBEC3D gene to outside databases

Previous GC identifers: GC22U990236 GC22P036032 GC22P037660 GC22P037741 GC22P039380 GC22P022391 GC22P039411 GC22P039412 GC22P039414


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for APOBEC3D Gene:
This gene is a member of the cytidine deaminase gene family. It is one of a group of related genes found in a
cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that
are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1 and inhibit
retroviruses, such as HIV, by deaminating cytosine residues in nascent retroviral cDNA. (provided by RefSeq, Jul
2008)

GeneCards Summary for APOBEC3D Gene:
APOBEC3D (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D) is a protein-coding gene. Diseases associated with APOBEC3D include albinism, and hiv-1. GO annotations related to this gene include hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines. An important paralog of this gene is APOBEC3G.

UniProtKB/Swiss-Prot: ABC3D_HUMAN, Q96AK3
Function: DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and
retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against
vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the
initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense
single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant
detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works
prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells.
Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded
RNA. May inhibit the mobility of LTR and non-LTR retrotransposons

Gene Wiki entry for APOBEC3D Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000022.11  NT_011520.13  NC_018933.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the APOBEC3D gene promoter:
         Max1   GR   USF1   SREBP-1c   SREBP-1b   Max   SREBP-1a   ZID   GR-alpha   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAPOBEC3D promoter sequence
   Search Chromatin IP Primers for APOBEC3D

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat APOBEC3D


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.1   Ensembl cytogenetic band:  22q13.1   HGNC cytogenetic band: 22q13.1

APOBEC3D Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
APOBEC3D gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P039418:  view genomic region     (about GC identifiers)

Start:
39,410,368 bp from pter      End:
39,429,281 bp from pter
Size:
18,914 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: ABC3D_HUMAN, Q96AK3 (See protein sequence)
Recommended Name: DNA dC->dU-editing enzyme APOBEC-3D  
Size: 386 amino acids; 46598 Da
Cofactor: Zinc (By similarity)
Miscellaneous: It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene
duplication, on chromosome 22
Secondary accessions: Q5JZ91 Q7Z2N2 Q7Z2N5 Q7Z2N6

Explore the universe of human proteins at neXtProt for APOBEC3D: NX_Q96AK3

Explore proteomics data for APOBEC3D at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • 2 DME Specific Peptides for APOBEC3D (Q96AK3)
     CFLSWFC  WLCYEVK 


    See APOBEC3D Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_689639.2  
    ENSEMBL proteins: 
     ENSP00000216099   ENSP00000370980   ENSP00000388017  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    APOBEC: Apolipoprotein B mRNA editing enzymes

    3 InterPro protein domains:
     IPR016192 APOBEC/CMP_deaminase_Zn-bd
     IPR007904 APOBEC_C
     IPR016193 Cytidine_deaminase-like

    Graphical View of Domain Structure for InterPro Entry Q96AK3

    ProtoNet protein and cluster: Q96AK3

    3 Blocks protein domains:
    IPB002125 Cytidine/deoxycytidylate deaminase
    IPB006121 Heavy metal transport/detoxification protein
    IPB007904 APOBEC-like


    UniProtKB/Swiss-Prot: ABC3D_HUMAN, Q96AK3
    Domain: The CMP/dCMP deaminase zinc-binding 1 domain mediates RNA binding, RNA-dependent oligomerization and
    virion incorporation whereas the CMP/dCMP deaminase zinc-binding 2 domain confers deoxycytidine deaminase
    activity and substrate sequence specificity
    Similarity: Belongs to the cytidine and deoxycytidylate deaminase family
    Similarity: Contains 2 CMP/dCMP deaminase zinc-binding domains


    APOBEC3D for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ABC3D_HUMAN, Q96AK3
    Function: DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and
    retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against
    vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the
    initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense
    single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant
    detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works
    prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells.
    Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded
    RNA. May inhibit the mobility of LTR and non-LTR retrotransposons
    Catalytic activity: Cytidine + H(2)O = uridine + NH(3)
    Enzyme regulation: Antiviral activity is neutralized by the HIV-1 virion infectivity factor (VIF), that prevents
    its incorporation into progeny virions by both inhibiting its translation and/or by inducing its ubiquitination
    and subsequent degradation by the 26S proteasome

         Enzyme Numbers (IUBMB): EC 3.5.42 EC 3.5.4.-1

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0008270zinc ion binding IEA--
    GO:0016814hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines IEA--
         
    APOBEC3D for ontologies           About GeneDecksing


    Animal Models:
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ABC3D_HUMAN, Q96AK3: Cytoplasm. Cytoplasm, P-body
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4
    cytosol2
    extracellular1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000932cytoplasmic mRNA processing body IDA--
    GO:0005737cytoplasm IDA--

    APOBEC3D for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for APOBEC3D
    Interactions:

        Search GeneGlobe Interaction Network for APOBEC3D

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for APOBEC3D (ENSP000002160994) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    A1CFENSP000002826414STRING: ENSP00000282641
    APOBEC3FENSP000003097494STRING: ENSP00000309749
    APOBEC3GENSP000003850574STRING: ENSP00000385057
    SHBGENSP000003698164STRING: ENSP00000369816
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0010529negative regulation of transposition IDA--
    GO:0045087innate immune response IEA--
    GO:0045869negative regulation of single stranded viral RNA replication via double stranded DNA intermediate IDA--
    GO:0051607defense response to virus IDA--
    GO:0070383DNA cytosine deamination IDA--

    APOBEC3D for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for APOBEC3D (ABC3D)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for APOBEC3D gene: 
    NM_152426.3  

    Unigene Cluster for APOBEC3D:

    Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
    Hs.658626  [show with all ESTs]
    Unigene Representative Sequence: NM_152426
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000216099(uc021wpq.1 uc003awt.4 uc010gxu.3 uc003awu.4)
    ENST00000381568 ENST00000427494
    Congresses - knowledge worth sharing:
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

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      QuantiFast Probe-based Assays in human, mouse, rat APOBEC3D

    Additional mRNA sequence: 

    BC017022.1 CR456396.1 EU527884.1 

    5 DOTS entries:

    DT.100740775  DT.86837797  DT.120661970  DT.75169912  DT.95087702 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    APOBEC3D expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CACCTGTAGT
    APOBEC3D Expression
    About this image

    APOBEC3D Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    APOBEC3D Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.658626

    UniProtKB/Swiss-Prot: ABC3D_HUMAN, Q96AK3
    Tissue specificity: Expressed in lymphoid organs. Also detected in non-lymphoid tissues including lung

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and chimp.

    Orthologs for APOBEC3D gene from 1 species (see representative species )    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chimpanzee
    (Pan troglodytes)
    Mammalia APOBEC3D1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like more 96.37(n)
    90.93(a)
      470274  XM_525657.4  XP_525657.4 


    ENSEMBL Gene Tree for APOBEC3D (if available)
    TreeFam Gene Tree for APOBEC3D (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for APOBEC3D gene
    APOBEC3G2  APOBEC3F2  APOBEC12  APOBEC22  APOBEC3B2  APOBEC3C2  APOBEC3A2  APOBEC3H2  
    AICDA2  
    9 SIMAP similar genes for APOBEC3D using alignment to 1 protein entry:     ABC3D_HUMAN:
    APOBEC3DE    APOBEC3C    APOBEC3F    APOBEC3B    AICDA    AID
    APOBEC3G    APOBEC2    APOBEC3A

    APOBEC3D for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for APOBEC3D
    PGOHUM00000246586


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for APOBEC3D (see all 463)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs358223331,2
    C--23334288(+) TCACTT/-TTTTT 1 -- us2k11Minor allele frequency- -:0.00NA 2
    rs1447411041,2
    C--39415413(+) TCAACA/GTGGTG 1 -- us2k10--------
    rs776574541,2
    F--39415587(+) CTGTGG/ACCTCC 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1873084491,2
    --39415593(+) CCTCCA/GTAGAA 1 -- us2k10--------
    rs57574241,2
    C,A--39415780(+) CTGGGA/GTCTCT 1 -- us2k14Minor allele frequency- G:0.37NA WA EA 360
    rs1485732081,2
    --39415800(+) AATAT-/CATC  
            
    TTTTT
    1 -- us2k10--------
    rs1165710571,2
    C,F--39415830(+) TTTGAG/CACAGA 1 -- us2k11Minor allele frequency- C:0.04WA 118
    rs11397281,2
    A--39415905(+) tcccgA/Ggttta 1 -- us2k11Minor allele frequency- G:0.00NA 2
    rs1917098551,2
    --39415915(+) AAGCGA/TTTCTT 1 -- us2k10--------
    rs2013029411,2
    C--39415940(+) GAGTA-/CCT   
      GGGACT
    AAAGG
    1 -- cds10--------

    HapMap Linkage Disequilibrium report for APOBEC3D (39410368 - 39429281 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for APOBEC3D (see all 12):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2676044CNV Deletion23128226
    esv2724241CNV Deletion23290073
    esv2724243CNV Deletion23290073
    esv2724242CNV Deletion23290073
    nsv834196CNV Loss17160897
    nsv915084CNV Loss21882294
    nsv915080CNV Loss21882294
    nsv915083CNV Loss21882294
    nsv915079CNV Gain21882294
    nsv915081CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing APOBEC3D
    DNA2.0 Custom Variant and Variant Library Synthesis for APOBEC3D

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609900    OMIM disorders: --

    2 diseases for APOBEC3D:    
    About MalaCards
    albinism    hiv-1


    APOBEC3D for disorders           About GeneDecksing


    Export disorders for APOBEC3D gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for APOBEC3D gene, integrated from 10 sources (see all 40):
    (articles sorted by number of sources associating them with APOBEC3D)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22. (PubMed id 11863358)1, 2, 3 Jarmuz A....Navaratnam N. (Genomics 2002)
    2. APOBEC3G restricts HIV-1 to a greater extent than APOBEC3F and APOBEC3DE in human primary CD4+ t cells and macrophages. (PubMed id 23097438)1, 2 Chaipan C.... Pathak V.K. (J. Virol. 2013)
    3. Endogenous origins of HIV-1 G-to-A hypermutation and restriction in the nonpermissive T cell line CEM2n. (PubMed id 22807680)1, 2 Refsland E.W.... Harris R.S. (PLoS Pathog. 2012)
    4. Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1. (PubMed id 21835787)1, 2 Hultquist J.F.... Harris R.S. (J. Virol. 2011)
    5. The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelements. (PubMed id 18304004)1, 2 Chiu Y.L. and Greene W.C. (Annu. Rev. Immunol. 2008)
    6. Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business. (PubMed id 12683974)1, 2 Wedekind J.E.... Smith H.C. (Trends Genet. 2003)
    7. Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif. (PubMed id 12859895)1, 2 Mariani R.... Landau N.R. (Cell 2003)
    8. The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I.... Wright H. (Nature 1999)
    9. The suppression of HIV-1 infection by APOBEC3 proteins in primary human CD4+ T cells is associated with the inhibition of processive reverse transcription as well as excessive cytidine deamination. (PubMed id 23152537)2 Gillick K....Malim M.H. (J. Virol. 2013)
    10. Identification and antiviral activity of common polymorphisms in the APOBEC3 locus in human populations. (PubMed id 23755966)1 Duggal N.K....Emerman M. (Virology 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 140564 HGNC: 17354 Ensembl:ENSG00000243811 euGenes: HUgn140564 ECgene: APOBEC3D
    H-InvDB: APOBEC3D

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for APOBEC3D Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for APOBEC3D gene:
    Search GeneIP for patents involving APOBEC3D

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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