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APOBEC3C Gene

protein-coding   GIFtS: 50
GCID: GC22P039410

Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like...

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3C1 2     ARP52
Phorbolin I2 3     Apolipoprotein B Editing Enzyme Catalytic Polypeptide-Like 3C2
A3C2 3     bK150C2.32
APOBEC1L2 3     DNA DC->DU-Editing Enzyme APOBEC-3C2
PBI2 3     Probable DNA DC->DU-Editing Enzyme APOBEC-3C2
ARDC22     APOBEC1-like3
ARDC42     EC 3.5.4.-3

External Ids:    HGNC: 173531   Entrez Gene: 273502   Ensembl: ENSG000002445097   OMIM: 6077505   UniProtKB: Q9NRW33   

Export aliases for APOBEC3C gene to outside databases

Previous GC identifers: GC22U990105 GC22P036025 GC22P037653 GC22P037734 GC22P039379 GC22P022378


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for APOBEC3C Gene:
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found
in a cluster thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins
that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is
thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. (provided by
RefSeq, Jul 2008)

GeneCards Summary for APOBEC3C Gene:
APOBEC3C (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C) is a protein-coding gene. GO annotations related to this gene include hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines. An important paralog of this gene is APOBEC3G.

UniProtKB/Swiss-Prot: ABC3C_HUMAN, Q9NRW3
Function: DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and
retrotransposon mobility via deaminase-dependent and -independent mechanisms. After the penetration of retroviral
nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the
conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in
the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along
with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient
antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate
double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity against simian immunodeficiency
virus (SIV), hepatitis B virus (HBV), herpes simplex virus 1 (HHV-1) and Epstein-Barr virus (EBV) and may inhibit
the mobility of LTR and non-LTR retrotransposons. May also play a role in the epigenetic regulation of gene
expression through the process of active DNA demethylation

Gene Wiki entry for APOBEC3C Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000022.10  NC_018933.2  NT_011520.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the APOBEC3C gene promoter:
         Max1   GR   USF1   SREBP-1c   SREBP-1b   Max   SREBP-1a   ZID   GR-alpha   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAPOBEC3C promoter sequence
   Search Chromatin IP Primers for APOBEC3C

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat APOBEC3C


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.1   Ensembl cytogenetic band:  22q13.1   HGNC cytogenetic band: 22q13.1-q13.2

APOBEC3C Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
APOBEC3C gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P039410:  view genomic region     (about GC identifiers)

Start:
39,410,088 bp from pter      End:
39,416,357 bp from pter
Size:
6,270 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ABC3C_HUMAN, Q9NRW3 (See protein sequence)
Recommended Name: DNA dC->dU-editing enzyme APOBEC-3C  
Size: 190 amino acids; 22826 Da
Cofactor: Zinc (By similarity)
Subunit: Homodimer. Interacts with human foamy virus protein Bet; this interaction does not induce APOBEC3C
degradation, but prevents dimerization and incorporation into virion of the latter. Interacts with TRIB3 and AGO2
Miscellaneous: It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene
duplication, on chromosome 22
Sequence caution: Sequence=AAF86650.1; Type=Frameshift; Positions=172;
2 PDB 3D structures from and Proteopedia for APOBEC3C:
3VM8 (3D)        3VOW (3D)    
Secondary accessions: B2R884 Q5JZ92 Q7Z2N7 Q96F12

Explore the universe of human proteins at neXtProt for APOBEC3C: NX_Q9NRW3

Explore proteomics data for APOBEC3C at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys10, Lys51
  • Modification sites at PhosphoSitePlus

  • See APOBEC3C Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055323.2  
    ENSEMBL proteins: 
     ENSP00000355340   ENSP00000390855  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    APOBEC: Apolipoprotein B mRNA editing enzymes

    3 InterPro protein domains:
     IPR016192 APOBEC/CMP_deaminase_Zn-bd
     IPR007904 APOBEC_C
     IPR016193 Cytidine_deaminase-like

    Graphical View of Domain Structure for InterPro Entry Q9NRW3

    ProtoNet protein and cluster: Q9NRW3

    2 Blocks protein domains:
    IPB002125 Cytidine/deoxycytidylate deaminase
    IPB007904 APOBEC-like


    UniProtKB/Swiss-Prot: ABC3C_HUMAN, Q9NRW3
    Similarity: Belongs to the cytidine and deoxycytidylate deaminase family
    Similarity: Contains 1 CMP/dCMP deaminase zinc-binding domain


    Find genes that share domains with APOBEC3C           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ABC3C_HUMAN, Q9NRW3
    Function: DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and
    retrotransposon mobility via deaminase-dependent and -independent mechanisms. After the penetration of retroviral
    nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the
    conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in
    the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along
    with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient
    antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate
    double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity against simian immunodeficiency
    virus (SIV), hepatitis B virus (HBV), herpes simplex virus 1 (HHV-1) and Epstein-Barr virus (EBV) and may inhibit
    the mobility of LTR and non-LTR retrotransposons. May also play a role in the epigenetic regulation of gene
    expression through the process of active DNA demethylation
    Catalytic activity: Cytidine + H(2)O = uridine + NH(3)
    Induction: Up-regulated by IFN-alpha

         Enzyme Number (IUBMB): EC 3.5.4.-1

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0005515protein binding IPI--
    GO:0008270zinc ion binding IEA--
    GO:0016814hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines IEA--
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with APOBEC3C           About GenesLikeMe


    Animal Models:
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    miRTarBase miRNAs that target APOBEC3C:
    hsa-mir-92a-3p (MIRT049344)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ABC3C_HUMAN, Q9NRW3: Nucleus. Cytoplasm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    extracellular3
    cytosol1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005737cytoplasm IDA--

    Find genes that share ontologies with APOBEC3C           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for APOBEC3C
    Interactions:

        Search GeneGlobe Interaction Network for APOBEC3C

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    Selected Interacting proteins for APOBEC3C (Q9NRW33 ENSP000003553404) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SHBGP042783, ENSP000003698164I2D: score=3 STRING: ENSP00000369816
    CNBPP626333I2D: score=2 
    UBCENSP000003448184STRING: ENSP00000344818
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    TRAF3ENSP000003324684STRING: ENSP00000332468
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0009972cytidine deamination IDA--
    GO:0010529negative regulation of transposition IDA16527742
    GO:0016032viral process IEA--
    GO:0019048modulation by virus of host morphology or physiology ----
    GO:0045071negative regulation of viral genome replication IDA--

    Find genes that share ontologies with APOBEC3C           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for APOBEC3C (ABC3C)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for APOBEC3C gene: 
    NM_014508.2  

    Unigene Cluster for APOBEC3C:

    Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
    Hs.441124  [show with all ESTs]
    Unigene Representative Sequence: BM473129
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000361441(uc003awr.3) ENST00000428892
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      QuantiFast Probe-based Assays in human, mouse, rat APOBEC3C

    Additional mRNA sequence: 

    AB208979.1 AF165520.1 AK313272.1 BC007954.2 BC011739.2 BC021080.1 CR456394.1 

    10 DOTS entries:

    DT.312711  DT.91671443  DT.100797885  DT.100797883  DT.100797884  DT.100740775  DT.100797882  DT.120661979 
    DT.100774417  DT.120661971 

    Selected AceView cDNA sequences (see all 142):

    BQ056344 BF508948 BM564332 AI217046 NM_145298 BQ921509 BX112841 CR456395 
    BF437832 BG744406 BX388243 BX332251 BX326730 BX331204 AI910810 CD656372 
    BU174800 BX367450 AW505140 AI799894 BE892372 CF142810 BM977965 BG758984 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    APOBEC3C expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    APOBEC3C Expression
    About this image

    APOBEC3C Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    APOBEC3C Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.441124

    UniProtKB/Swiss-Prot: ABC3C_HUMAN, Q9NRW3
    Tissue specificity: Expressed in spleen, testes, peripherical blood lymphocytes, heart, thymus, prostate and ovary

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and chimp.

    Orthologs for APOBEC3C gene from 1 species (see representative species )    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chimpanzee
    (Pan troglodytes)
    Mammalia APOBEC3C1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like more 99.12(n)
    97.89(a)
      100611714  NM_001251910.1  NP_001238839.1 


    ENSEMBL Gene Tree for APOBEC3C (if available)
    TreeFam Gene Tree for APOBEC3C (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for APOBEC3C gene
    APOBEC3G2  APOBEC3F2  APOBEC12  APOBEC22  APOBEC3B2  APOBEC3D2  APOBEC3A2  APOBEC3H2  
    AICDA2  
    11 SIMAP similar genes for APOBEC3C using alignment to 3 protein entries:     ABC3C_HUMAN (see all proteins):
    APOBEC3F    APOBEC3D    APOBEC3DE    bK150C2.9    APOBEC3B    APOBEC2
    AID    AICDA    APOBEC1    APOBEC3G    APOBEC3A

    Find genes that share paralogs with APOBEC3C           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for APOBEC3C (see all 239)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs60013791,2
    C,F,A--39408307(+) aaggcG/Acatcc 1 -- us2k12Minor allele frequency- A:0.50NA 4
    rs560509321,2
    C--39408321(+) ACAGCT/CCTAAA 1 -- us2k13Minor allele frequency- C:0.25WA CSA 4
    rs1926658421,2
    --39408364(+) TTCTGC/GGAGCA 1 -- us2k10--------
    rs2019032391,2
    C--39408495(+) ATCTC-/TCTT  
            
    TCTTT
    1 -- us2k10--------
    rs1832444951,2
    --39408507(+) TTCCCC/TCACAA 1 -- us2k10--------
    rs1876367581,2
    --39408596(+) CTTAGA/CTGAAC 1 -- us2k10--------
    rs753461861,2
    --39408686(+) GCCGTA/GAGCCT 1 -- us2k10--------
    rs1913389641,2
    --39408715(+) CCACCA/GCTTGA 1 -- us2k10--------
    rs1844015681,2
    --39408786(+) TCCCCA/GTGTGT 1 -- us2k10--------
    rs1493761731,2
    --39408803(+) GAGAAA/GTCGTA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for APOBEC3C (39410088 - 39416357 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for APOBEC3C:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2724241CNV Deletion23290073
    nsv834196CNV Loss17160897
    esv1001536CNV Loss20482838
    nsv915080CNV Loss21882294
    nsv915083CNV Loss21882294
    nsv915079CNV Gain21882294
    nsv915081CNV Gain21882294
    nsv915082CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 607750    OMIM disorders: --


    Find genes that share disorders with APOBEC3C           About GenesLikeMe


    Export disorders for APOBEC3C gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for APOBEC3C gene, integrated from 10 sources (see all 80):
    (articles sorted by number of sources associating them with APOBEC3C)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22. (PubMed id 11863358)1, 2, 3 Jarmuz A....Navaratnam N. (Genomics 2002)
    2. The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelements. (PubMed id 18304004)1, 2 Chiu Y.L. and Greene W.C. (Annu. Rev. Immunol. 2008)
    3. APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons. (PubMed id 16527742)1, 2 Chen H.... Weitzman M.D. (Curr. Biol. 2006)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (Genome Biol. 2004)
    6. APOBEC3B and APOBEC3C are potent inhibitors of simian immunodeficiency virus replication. (PubMed id 15466872)1, 2 Yu Q.... Landau N.R. (J. Biol. Chem. 2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif. (PubMed id 12859895)1, 2 Mariani R.... Landau N.R. (Cell 2003)
    9. The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I.... Wright H. (Nature 1999)
    10. Species-specific inhibition of APOBEC3C by the prototype foamy virus protein bet. (PubMed id 19074429)2, 9 Perkovic M.... Muenk C. (J. Biol. Chem. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 27350 HGNC: 17353 AceView: APOBEC3F Ensembl:ENSG00000244509 euGenes: HUgn27350
    ECgene: APOBEC3C H-InvDB: APOBEC3C

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for APOBEC3C Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for APOBEC3C gene:
    Search GeneIP for patents involving APOBEC3C

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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