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APOBEC3A Gene

protein-coding   GIFtS: 49
GCID: GC22P039348

Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like...

  See APOBEC3A-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3A1 2     Phorbolin 12
A3A2 3     phorbolin-12
PHRBN2 5     Probable DNA DC->DU-Editing Enzyme APOBEC-3A2
Phorbolin I1     EC 3.5.4.-3
ARP32     Phorbolin-13
bK150C2.12     EC 3.5.48
DNA DC->DU-Editing Enzyme APOBEC-3A2     

External Ids:    HGNC: 173431   Entrez Gene: 2003152   Ensembl: ENSG000001283837   OMIM: 6071095   UniProtKB: P319413   

Export aliases for APOBEC3A gene to outside databases

Previous GC identifers: GC22P035968 GC22P037591 GC22P037596 GC22P037678 GC22Pr39368


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for APOBEC3A Gene:
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found
in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins
that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein
encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in
immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is
deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other
mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two
transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Jul 2012)

GeneCards Summary for APOBEC3A Gene:
APOBEC3A (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A) is a protein-coding gene. Diseases associated with APOBEC3A include human t-cell leukemia virus type 1, and hepatitis b virus infection. GO annotations related to this gene include cytidine deaminase activity and deoxycytidine deaminase activity. An important paralog of this gene is APOBEC3G.

UniProtKB/Swiss-Prot: ABC3A_HUMAN, P31941
Function: DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility
of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia
virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets
single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic
hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene
expression through the process of active DNA demethylation

Gene Wiki entry for APOBEC3A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the APOBEC3A gene promoter:
         SRF   SRF (504 AA)   LCR-F1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAPOBEC3A promoter sequence
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Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat APOBEC3A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.1-q13.2   Ensembl cytogenetic band:  22q13.1   HGNC cytogenetic band: 22q13.1-q13.2

APOBEC3A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
APOBEC3A gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P039348:  view genomic region     (about GC identifiers)

Start:
39,348,746 bp from pter      End:
39,359,188 bp from pter
Size:
10,443 bases      Orientation:
plus strand

1 alternative location:
Chr22+,NW_003315972 73,230-78,546     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ABC3A_HUMAN, P31941 (See protein sequence)
Recommended Name: DNA dC->dU-editing enzyme APOBEC-3A  
Size: 199 amino acids; 23012 Da
Cofactor: Zinc (By similarity)
Subunit: Interacts with AGO2. Interacts with TRIB3 (via N-terminus)
Miscellaneous: It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene
duplication, on chromosome 22
1 PDB 3D structure from and Proteopedia for APOBEC3A:
2M65 (3D)    
Secondary accessions: A0AVM1 Q12807 Q5JZ93 Q9UH18
Alternative initiation: 2 isoforms:  P31941-1   P31941-2   (Enzymatically active)

Explore the universe of human proteins at neXtProt for APOBEC3A: NX_P31941

Explore proteomics data for APOBEC3A at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • 3 DME Specific Peptides for APOBEC3A (P31941)
     FTSNFNN  PFQPWDGL  EHSQALSGRL 


    See APOBEC3A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001257335.1  NP_663745.1  

    ENSEMBL proteins: 
     ENSP00000384359   ENSP00000249116  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    APOBEC: Apolipoprotein B mRNA editing enzymes

    3 InterPro protein domains:
     IPR016192 APOBEC/CMP_deaminase_Zn-bd
     IPR007904 APOBEC_C
     IPR016193 Cytidine_deaminase-like

    Graphical View of Domain Structure for InterPro Entry P31941

    ProtoNet protein and cluster: P31941

    2 Blocks protein domains:
    IPB002125 Cytidine/deoxycytidylate deaminase
    IPB007904 APOBEC-like


    UniProtKB/Swiss-Prot: ABC3A_HUMAN, P31941
    Similarity: Belongs to the cytidine and deoxycytidylate deaminase family
    Similarity: Contains 1 CMP/dCMP deaminase zinc-binding domain


    Find genes that share domains with APOBEC3A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ABC3A_HUMAN, P31941
    Function: DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility
    of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia
    virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets
    single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic
    hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene
    expression through the process of active DNA demethylation
    Catalytic activity: Cytidine + H(2)O = uridine + NH(3)
    Induction: Up-regulated by interferon and CpG single-stranded DNA (at protein level)

         Enzyme Numbers (IUBMB): EC 3.5.42 EC 3.5.4.-1

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0004126cytidine deaminase activity IMP--
    GO:0005515protein binding IPI--
    GO:0008270zinc ion binding IEA--
    GO:0016814hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines ----
         
    Find genes that share ontologies with APOBEC3A           About GenesLikeMe


    Animal Models:
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ABC3A_HUMAN, P31941: Nucleus. Cytoplasm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    extracellular2
    cytosol1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--

    Find genes that share ontologies with APOBEC3A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for APOBEC3A
    Interactions:

        Search GeneGlobe Interaction Network for APOBEC3A

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for APOBEC3A (ENSP000002491164) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0009972cytidine deamination IMP--
    GO:0010529negative regulation of transposition IDA16527742
    GO:0044356clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine IDA--
    GO:0045071negative regulation of viral genome replication IDA16527742
    GO:0045087innate immune response IDA--

    Find genes that share ontologies with APOBEC3A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for APOBEC3A (ABC3A)

    1 Novoseek inferred chemical compound relationship for APOBEC3A gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cytidine 84.7 3 16720547 (1), 10469298 (1), 20178977 (1)



    Find genes that share compounds with APOBEC3A           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for APOBEC3A gene (2 alternative transcripts): 
    NM_001270406.1  NM_145699.3  

    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000495988 ENST00000402255 ENST00000488758 ENST00000249116(uc003awn.2 uc011aob.1 uc011aoc.1)

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    Selected AceView cDNA sequences (see all 55):

    BX114955 CR456393 BE644606 BI029063 NM_004900 BI029065 BU584024 C00488 
    BM463931 BU178985 BC031803 AA603662 T71211 BU584432 AI281048 BI030278 
    BV197494 U03891 CB218515 BF514663 AI761325 AW368715 BM687484 AI222763 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    APOBEC3A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATTGCAAGA
    APOBEC3A Expression
    About this image


    APOBEC3A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Bone (Muscoskeletal System)
             Bone Marrow
    APOBEC3A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    APOBEC3A Protein Expression

    UniProtKB/Swiss-Prot: ABC3A_HUMAN, P31941
    Tissue specificity: Expressed in peripheral leukocytes with higher expression in CD14-positive phagocytic cells.
    Highly expressed in keratinocytes and in periphery blood monocytes. Also detected in non-lymphoid tissues
    including lung and adipose tissues. Found at high levels in colorectal adenocarcinoma, Burkitt's lymphoma and
    chronic myelogenous leukemia

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of mammals.

    Orthologs for APOBEC3A gene from Selected species (see all 3)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    dog
    (Canis familiaris)
    Mammalia APOBEC3A1 DNA dC->dU-editing enzyme APOBEC-3G-like 65.38(n)
    52.31(a)
      610077  XM_847476.2  XP_852569.1 


    ENSEMBL Gene Tree for APOBEC3A (if available)
    TreeFam Gene Tree for APOBEC3A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for APOBEC3A gene
    APOBEC3G2  APOBEC3F2  APOBEC12  APOBEC22  APOBEC3B2  APOBEC3D2  APOBEC3C2  APOBEC3H2  
    AICDA2  
    10 SIMAP similar genes for APOBEC3A using alignment to 2 protein entries:     ABC3A_HUMAN (see all proteins):
    APOBEC3B    APOBEC3G    AID    AICDA    APOBEC3F    APOBEC3C
    APOBEC2    APOBEC3D    APOBEC3DE    APOBEC3H

    Find genes that share paralogs with APOBEC3A           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for APOBEC3A
    PGOHUM00000259961


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for APOBEC3A (see all 34)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1385871431,2
    --39351744(+) TCTCTC/TCTCTC 2 -- us2k10--------
    rs1164264631,2
    C,F--39351866(+) CATCAG/AATGAG 2 -- us2k11Minor allele frequency- A:0.07WA 118
    rs559351551,2
    C,F--39352175(+) GAGACG/ACCCCA 2 -- us2k11Minor allele frequency- A:0.06NA 120
    rs734199101,2
    C,F--39352232(+) TCCCCA/GTAGAA 2 -- us2k13Minor allele frequency- G:0.11WA CSA 122
    rs573203291,2
    C,F--39352282(+) GTATTT/CGCTCC 2 -- us2k11Minor allele frequency- C:0.12WA 118
    rs1177672091,2
    C,F--39352312(+) TTGAGC/ACAGGG 2 -- us2k11Minor allele frequency- A:0.01NA 120
    rs1505680101,2
    --39352407(+) GTCTC-/TGG   
      CCCAGG
    TGGGC
    2 -- us2k10--------
    rs1400526931,2
    --39352433(+) ACTGCA/GGGGCG 2 -- us2k10--------
    rs1908984931,2
    --39352491(+) TCAGAC/TTCACA 2 -- us2k10--------
    rs1153455641,2
    F--39352565(+) AGGGGA/CCATCT 2 -- us2k11Minor allele frequency- C:0.03WA 118

    HapMap Linkage Disequilibrium report for APOBEC3A (39348746 - 39359188 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for APOBEC3A (see all 30):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2724240CNV Deletion23290073
    esv2658587CNV Deletion23128226
    esv2724238CNV Deletion23290073
    dgv833e199CNV Deletion23128226
    esv2495318CNV Deletion19546169
    esv998756CNV Deletion20482838
    esv2670964CNV Deletion23128226
    nsv829225CNV Loss20364138
    nsv829221CNV Loss20364138
    nsv829224CNV Loss20364138

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 607109    OMIM disorders: --

    3 diseases for APOBEC3A:    
    About MalaCards
    human t-cell leukemia virus type 1    hepatitis b virus infection    colorectal adenocarcinoma


    Find genes that share disorders with APOBEC3A           About GenesLikeMe

    1 Novoseek inferred disease relationship for APOBEC3A gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    psoriasis 45.7 1 10469298 (1)

    Genetic Association Database (GAD): APOBEC3A
    Human Genome Epidemiology (HuGE) Navigator: APOBEC3A (2 documents)

    Export disorders for APOBEC3A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for APOBEC3A gene, integrated from 10 sources (see all 58):
    (articles sorted by number of sources associating them with APOBEC3A)
        Utopia: connect your pdf to the dynamic
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    1. Psoriasis upregulated phorbolin-1 shares structural but not functional similarity to the mRNA-editing protein apobec-1. (PubMed id 10469298)1, 2, 3, 9 Madsen P.P.... Celis J.E. (J. Invest. Dermatol. 1999)
    2. An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22. (PubMed id 11863358)1, 2, 3 Jarmuz A....Navaratnam N. (Genomics 2002)
    3. APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons. (PubMed id 16527742)1, 2, 9 Chen H.... Weitzman M.D. (Curr. Biol. 2006)
    4. Human Tribbles 3 protects nuclear DNA from cytidine deamination by APOBEC3A. (PubMed id 22977230)1, 2 Aynaud M.M.... Vartanian J.P. (J. Biol. Chem. 2012)
    5. APOBEC3A, APOBEC3B, and APOBEC3H haplotype 2 restrict human T- lymphotropic virus type 1. (PubMed id 22457529)1, 2 Ooms M.... Muenk C. (J. Virol. 2012)
    6. APOBEC3A can activate the DNA damage response and cause cell-cycle arrest. (PubMed id 21460793)1, 2 Landry S.... Weitzman M.D. (EMBO Rep. 2011)
    7. Structure-function analyses point to a polynucleotide-accommodating groove essential for APOBEC3A restriction activities. (PubMed id 21123384)1, 2 Bulliard Y.... Trono D. (J. Virol. 2011)
    8. Innate immune signaling induces high levels of TC-specific deaminase activity in primary monocyte-derived cells through expression of APOBEC3A isoforms. (PubMed id 20615867)1, 2 Thielen B.K....Lingappa J.R. (J. Biol. Chem. 2010)
    9. APOBEC3 proteins mediate the clearance of foreign DNA from human cells. (PubMed id 20062055)1, 2 Stenglein M.D.... Harris R.S. (Nat. Struct. Mol. Biol. 2010)
    10. Effects of structural variations of APOBEC3A and APOBEC3B genes in chronic hepatitis B virus infection. (PubMed id 19788695)1, 4 Abe H....Chayama K. (Hepatol. Res. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 200315 HGNC: 17343 AceView: APOBEC3BandAPOBEC3A Ensembl:ENSG00000128383 euGenes: HUgn200315
    ECgene: APOBEC3A H-InvDB: APOBEC3A

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for APOBEC3A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for APOBEC3A gene:
    Search GeneIP for patents involving APOBEC3A

    GeneCards and IP:
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