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Aliases for APOB-ICR Gene

Aliases for APOB-ICR Gene

  • APOB Intestinal Control Region (ICR) 3

External Ids for APOB-ICR Gene

Summaries for APOB-ICR Gene

Entrez Gene Summary for APOB-ICR Gene

  • This region represents a portion of a larger DNase I sensitive domain in intestinal cells. It contains DNase I hypersensitive sites corresponding to intestinal enhancers and other regulators of the apolipoprotein B (APOB) gene, located greater than 50 kb downstream. Enhancer activity is associated with binding by C/EBP, forkhead, and nuclear receptor family proteins, and responds to signalling by transforming growth factor beta. An additional regulatory sequence binds transcriptional repressor CTCF and can act as an insulator and an enhancer blocker. This region also includes a putative scaffold/matrix attachment region (S/MAR). [provided by RefSeq, Oct 2015]

GeneCards Summary for APOB-ICR Gene

APOB-ICR (APOB Intestinal Control Region (ICR)) is an Uncategorized gene.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for APOB-ICR Gene

Genomics for APOB-ICR Gene

Genomic Location for APOB-ICR Gene

Chromosome:
2
Orientation:
Unknown strand

Genomic View for APOB-ICR Gene

No data available for Regulatory Elements , Cytogenetic band and RefSeq DNA sequence for APOB-ICR Gene

Proteins for APOB-ICR Gene

Post-translational modifications for APOB-ICR Gene

No Post-translational modifications

No data available for DME Specific Peptides for APOB-ICR Gene

Domains & Families for APOB-ICR Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for APOB-ICR Gene

Function for APOB-ICR Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for APOB-ICR Gene

Localization for APOB-ICR Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for APOB-ICR Gene

Pathways & Interactions for APOB-ICR Gene

SuperPathways for APOB-ICR Gene

No Data Available

Interacting Proteins for APOB-ICR Gene

Gene Ontology (GO) - Biological Process for APOB-ICR Gene

None

No data available for Pathways by source and SIGNOR curated interactions for APOB-ICR Gene

Drugs & Compounds for APOB-ICR Gene

No Compound Related Data Available

Transcripts for APOB-ICR Gene

Alternative Splicing Database (ASD) splice patterns (SP) for APOB-ICR Gene

No ASD Table

No data available for mRNA/cDNA for APOB-ICR Gene

Expression for APOB-ICR Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for APOB-ICR Gene

Orthologs for APOB-ICR Gene

No data available for Orthologs and Evolution for APOB-ICR Gene

Paralogs for APOB-ICR Gene

No data available for Paralogs for APOB-ICR Gene

Variants for APOB-ICR Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for APOB-ICR Gene

Disorders for APOB-ICR Gene

No disorders were found for APOB-ICR Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for APOB-ICR Gene

Publications for APOB-ICR Gene

  1. Regulation of human apolipoprotein B gene expression at multiple levels. (PMID: 14516783) Wang A.B. … Liang C.C. (Exp. Cell Res. 2003) 3 64
  2. Differential, tissue-specific, transcriptional regulation of apolipoprotein B secretion by transforming growth factor beta. (PMID: 12177061) Singh K. … Hussain M.M. (J. Biol. Chem. 2002) 3 64
  3. The 5' boundary of the human apolipoprotein B chromatin domain in intestinal cells. (PMID: 11389587) Antes T.J. … Levy-Wilson B. (Biochemistry 2001) 3 64
  4. Human apolipoprotein B gene intestinal control region. (PMID: 11389586) Antes T.J. … Levy-Wilson B. (Biochemistry 2001) 3 64
  5. HNF-3 beta, C/EBP beta, and HNF-4 act in synergy to enhance transcription of the human apolipoprotein B gene in intestinal cells. (PMID: 11244563) Antes T.J. … Levy-Wilson B. (DNA Cell Biol. 2001) 3 64

Products for APOB-ICR Gene

Sources for APOB-ICR Gene

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